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Items: 1 to 50 of 54

1.

Simultaneous Immunoglobulin A and G Glycopeptide Profiling for High-Throughput Applications.

Momčilović A, de Haan N, Hipgrave Ederveen AL, Bondt A, Koeleman CAM, Falck D, de Neef LA, Mesker WE, Tollenaar R, de Ru A, van Veelen P, Wuhrer M, Dotz V.

Anal Chem. 2020 Mar 17;92(6):4518-4526. doi: 10.1021/acs.analchem.9b05722. Epub 2020 Mar 4.

PMID:
32091889
2.

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

Verheyen A, Diels A, Reumers J, Van Hoorde K, Van den Wyngaert I, van Outryve d'Ydewalle C, De Bondt A, Kuijlaars J, De Muynck L, De Hoogt R, Bretteville A, Jaensch S, Buist A, Cabrera-Socorro A, Wray S, Ebneth A, Roevens P, Royaux I, Peeters PJ.

Stem Cell Reports. 2019 Aug 13;13(2):434-435. doi: 10.1016/j.stemcr.2019.07.007. No abstract available.

3.

Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons.

Kreir M, De Bondt A, Van den Wyngaert I, Teuns G, Lu HR, Gallacher DJ.

Eur J Pharmacol. 2019 Sep 5;858:172474. doi: 10.1016/j.ejphar.2019.172474. Epub 2019 Jun 22.

PMID:
31238068
4.

N-Linked Glycans in the Variable Domain of IgG Anti-Citrullinated Protein Antibodies Predict the Development of Rheumatoid Arthritis.

Hafkenscheid L, de Moel E, Smolik I, Tanner S, Meng X, Jansen BC, Bondt A, Wuhrer M, Huizinga TWJ, Toes REM, El-Gabalawy H, Scherer HU.

Arthritis Rheumatol. 2019 Oct;71(10):1626-1633. doi: 10.1002/art.40920. Epub 2019 Sep 2.

5.

Serum protein N-glycosylation changes in multiple myeloma.

Zhang Z, Westhrin M, Bondt A, Wuhrer M, Standal T, Holst S.

Biochim Biophys Acta Gen Subj. 2019 May;1863(5):960-970. doi: 10.1016/j.bbagen.2019.03.001. Epub 2019 Mar 5.

PMID:
30844485
6.

Correction: MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.

Beke L, Kig C, Linders JTM, Boens S, Boeckx A, van Heerde E, Parade M, De Bondt A, Van den Wyngaert I, Bashir T, Ogata S, Meerpoel L, Van Eynde A, Johnson CN, Beullens M, Brehmer D, Bollen M.

Biosci Rep. 2018 Nov 30;38(6). pii: BSR-20150194_COR. doi: 10.1042/BSR-20150194_COR. Print 2018 Dec 21. No abstract available.

7.

Comparative Glycomics of Immunoglobulin A and G From Saliva and Plasma Reveals Biomarker Potential.

Plomp R, de Haan N, Bondt A, Murli J, Dotz V, Wuhrer M.

Front Immunol. 2018 Oct 23;9:2436. doi: 10.3389/fimmu.2018.02436. eCollection 2018.

8.

High-throughput Serum N-Glycomics: Method Comparison and Application to Study Rheumatoid Arthritis and Pregnancy-associated Changes.

Reiding KR, Bondt A, Hennig R, Gardner RA, O'Flaherty R, Trbojević-Akmačić I, Shubhakar A, Hazes JMW, Reichl U, Fernandes DL, Pučić-Baković M, Rapp E, Spencer DIR, Dolhain RJEM, Rudd PM, Lauc G, Wuhrer M.

Mol Cell Proteomics. 2019 Jan;18(1):3-15. doi: 10.1074/mcp.RA117.000454. Epub 2018 Sep 21.

9.

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

Verheyen A, Diels A, Reumers J, Van Hoorde K, Van den Wyngaert I, van Outryve d'Ydewalle C, De Bondt A, Kuijlaars J, De Muynck L, De Hoogt R, Bretteville A, Jaensch S, Buist A, Cabrera-Socorro A, Wray S, Ebneth A, Roevens P, Royaux I, Peeters PJ.

Stem Cell Reports. 2018 Aug 14;11(2):363-379. doi: 10.1016/j.stemcr.2018.06.022. Epub 2018 Jul 26. Erratum in: Stem Cell Reports. 2019 Aug 13;13(2):434-435.

10.

Trace N-glycans including sulphated species may originate from various plasma glycoproteins and not necessarily IgG.

Lauc G, Vučković F, Bondt A, Pezer M, Wuhrer M.

Nat Commun. 2018 Jul 25;9(1):2916. doi: 10.1038/s41467-018-05173-w. No abstract available.

11.

HappyTools: A software for high-throughput HPLC data processing and quantitation.

Jansen BC, Hafkenscheid L, Bondt A, Gardner RA, Hendel JL, Wuhrer M, Spencer DIR.

PLoS One. 2018 Jul 6;13(7):e0200280. doi: 10.1371/journal.pone.0200280. eCollection 2018.

12.

Low amounts of bisecting glycans characterize cerebrospinal fluid-borne IgG.

Knopf J, Magorivska I, Maler JM, Spitzer P, Bilyy R, Biermann MHC, Hychka K, Bondt A, Wuhrer M, Toes REM, Schett G, Herrmann M, Muñoz LE.

J Neuroimmunol. 2018 Jul 15;320:19-24. doi: 10.1016/j.jneuroim.2018.04.010. Epub 2018 Apr 16.

PMID:
29759137
13.

Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women.

Engdahl C, Bondt A, Harre U, Raufer J, Pfeifle R, Camponeschi A, Wuhrer M, Seeling M, Mårtensson IL, Nimmerjahn F, Krönke G, Scherer HU, Forsblad-d'Elia H, Schett G.

Arthritis Res Ther. 2018 May 2;20(1):84. doi: 10.1186/s13075-018-1586-z.

14.

High-Throughput Gene Expression Profiles to Define Drug Similarity and Predict Compound Activity.

De Wolf H, Cougnaud L, Van Hoorde K, De Bondt A, Wegner JK, Ceulemans H, Göhlmann H.

Assay Drug Dev Technol. 2018 Apr;16(3):162-176. doi: 10.1089/adt.2018.845.

PMID:
29658791
15.

ACPA IgG galactosylation associates with disease activity in pregnant patients with rheumatoid arthritis.

Bondt A, Hafkenscheid L, Falck D, Kuijper TM, Rombouts Y, Hazes JMW, Wuhrer M, Dolhain RJEM.

Ann Rheum Dis. 2018 Aug;77(8):1130-1136. doi: 10.1136/annrheumdis-2018-212946. Epub 2018 Apr 3.

PMID:
29615411
16.

Do in vitro assays in rat primary neurons predict drug-induced seizure liability in humans?

Kreir M, Van Deuren B, Versweyveld S, De Bondt A, Van den Wyngaert I, Van der Linde H, Lu HR, Teuns G, Gallacher DJ.

Toxicol Appl Pharmacol. 2018 May 1;346:45-57. doi: 10.1016/j.taap.2018.03.028. Epub 2018 Mar 26.

PMID:
29596924
17.

Serum Protein N-Glycosylation Changes with Rheumatoid Arthritis Disease Activity during and after Pregnancy.

Reiding KR, Vreeker GCM, Bondt A, Bladergroen MR, Hazes JMW, van der Burgt YEM, Wuhrer M, Dolhain RJEM.

Front Med (Lausanne). 2018 Jan 8;4:241. doi: 10.3389/fmed.2017.00241. eCollection 2017.

18.

IgA N- and O-glycosylation profiling reveals no association with the pregnancy-related improvement in rheumatoid arthritis.

Bondt A, Nicolardi S, Jansen BC, Kuijper TM, Hazes JMW, van der Burgt YEM, Wuhrer M, Dolhain RJEM.

Arthritis Res Ther. 2017 Jul 5;19(1):160. doi: 10.1186/s13075-017-1367-0.

19.

Application of optical action potentials in human induced pluripotent stem cells-derived cardiomyocytes to predict drug-induced cardiac arrhythmias.

Lu HR, Hortigon-Vinagre MP, Zamora V, Kopljar I, De Bondt A, Gallacher DJ, Smith G.

J Pharmacol Toxicol Methods. 2017 Sep;87:53-67. doi: 10.1016/j.vascn.2017.05.001. Epub 2017 May 10.

PMID:
28501647
20.

Progressive leukoencephalopathy impairs neurobehavioral development in sialin-deficient mice.

Stroobants S, Van Acker NG, Verheijen FW, Goris I, Daneels GF, Schot R, Verbeek E, Knaapen MW, De Bondt A, Göhlmann HW, Crauwels ML, Mancini GM, Andries LJ, Moechars DW, D'Hooge R.

Exp Neurol. 2017 May;291:106-119. doi: 10.1016/j.expneurol.2017.02.009. Epub 2017 Feb 9.

21.

Chronic drug-induced effects on contractile motion properties and cardiac biomarkers in human induced pluripotent stem cell-derived cardiomyocytes.

Kopljar I, De Bondt A, Vinken P, Teisman A, Damiano B, Goeminne N, Van den Wyngaert I, Gallacher DJ, Lu HR.

Br J Pharmacol. 2017 Nov;174(21):3766-3779. doi: 10.1111/bph.13713. Epub 2017 Feb 8.

22.

Age-dependent concomitant changes in synaptic dysfunction and GABAergic pathway in the APP/PS1 mouse model.

Oyelami T, Bondt A, den Wyngaert IV, Hoorde KV, Hoskens L, Shaban H, Kemp JA, Drinkenburg WH.

Acta Neurobiol Exp (Wars). 2016;76(4):282-293.

23.

Maternal and Fetal Mechanisms of B Cell Regulation during Pregnancy: Human Chorionic Gonadotropin Stimulates B Cells to Produce IL-10 While Alpha-Fetoprotein Drives Them into Apoptosis.

Fettke F, Schumacher A, Canellada A, Toledo N, Bekeredjian-Ding I, Bondt A, Wuhrer M, Costa SD, Zenclussen AC.

Front Immunol. 2016 Dec 8;7:495. doi: 10.3389/fimmu.2016.00495. eCollection 2016.

24.

Structural Analysis of Variable Domain Glycosylation of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Reveals the Presence of Highly Sialylated Glycans.

Hafkenscheid L, Bondt A, Scherer HU, Huizinga TW, Wuhrer M, Toes RE, Rombouts Y.

Mol Cell Proteomics. 2017 Feb;16(2):278-287. doi: 10.1074/mcp.M116.062919. Epub 2016 Dec 12.

25.

Fab glycosylation of immunoglobulin G does not associate with improvement of rheumatoid arthritis during pregnancy.

Bondt A, Wuhrer M, Kuijper TM, Hazes JM, Dolhain RJ.

Arthritis Res Ther. 2016 Nov 25;18(1):274.

26.

MALDI-TOF-MS reveals differential N-linked plasma- and IgG-glycosylation profiles between mothers and their newborns.

Jansen BC, Bondt A, Reiding KR, Scherjon SA, Vidarsson G, Wuhrer M.

Sci Rep. 2016 Sep 26;6:34001. doi: 10.1038/srep34001.

27.

Longitudinal monitoring of immunoglobulin A glycosylation during pregnancy by simultaneous MALDI-FTICR-MS analysis of N- and O-glycopeptides.

Bondt A, Nicolardi S, Jansen BC, Stavenhagen K, Blank D, Kammeijer GS, Kozak RP, Fernandes DL, Hensbergen PJ, Hazes JM, van der Burgt YE, Dolhain RJ, Wuhrer M.

Sci Rep. 2016 Jun 15;6:27955. doi: 10.1038/srep27955.

28.

Transcriptional Characterization of Compounds: Lessons Learned from the Public LINCS Data.

De Wolf H, De Bondt A, Turner H, Göhlmann HW.

Assay Drug Dev Technol. 2016 May;14(4):252-60. doi: 10.1089/adt.2016.715.

29.

In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System.

Knöspel F, Jacobs F, Freyer N, Damm G, De Bondt A, van den Wyngaert I, Snoeys J, Monshouwer M, Richter M, Strahl N, Seehofer D, Zeilinger K.

Int J Mol Sci. 2016 Apr 16;17(4):584. doi: 10.3390/ijms17040584.

30.

Pregnancy-associated serum N-glycome changes studied by high-throughput MALDI-TOF-MS.

Jansen BC, Bondt A, Reiding KR, Lonardi E, de Jong CJ, Falck D, Kammeijer GS, Dolhain RJ, Rombouts Y, Wuhrer M.

Sci Rep. 2016 Apr 14;6:23296. doi: 10.1038/srep23296.

31.

Functional and Transcriptional Characterization of Histone Deacetylase Inhibitor-Mediated Cardiac Adverse Effects in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Kopljar I, Gallacher DJ, De Bondt A, Cougnaud L, Vlaminckx E, Van den Wyngaert I, Lu HR.

Stem Cells Transl Med. 2016 May;5(5):602-12. doi: 10.5966/sctm.2015-0279. Epub 2016 Mar 31.

32.

Recent Advances in Clinical Glycoproteomics of Immunoglobulins (Igs).

Plomp R, Bondt A, de Haan N, Rombouts Y, Wuhrer M.

Mol Cell Proteomics. 2016 Jul;15(7):2217-28. doi: 10.1074/mcp.O116.058503. Epub 2016 Mar 23. Review.

33.

MassyTools: A High-Throughput Targeted Data Processing Tool for Relative Quantitation and Quality Control Developed for Glycomic and Glycoproteomic MALDI-MS.

Jansen BC, Reiding KR, Bondt A, Hipgrave Ederveen AL, Palmblad M, Falck D, Wuhrer M.

J Proteome Res. 2015 Dec 4;14(12):5088-98. doi: 10.1021/acs.jproteome.5b00658. Epub 2015 Nov 13.

PMID:
26565759
34.

Human plasma protein N-glycosylation.

Clerc F, Reiding KR, Jansen BC, Kammeijer GS, Bondt A, Wuhrer M.

Glycoconj J. 2016 Jun;33(3):309-43. doi: 10.1007/s10719-015-9626-2. Epub 2015 Nov 10. Review.

35.

MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.

Beke L, Kig C, Linders JT, Boens S, Boeckx A, van Heerde E, Parade M, De Bondt A, Van den Wyngaert I, Bashir T, Ogata S, Meerpoel L, Van Eynde A, Johnson CN, Beullens M, Brehmer D, Bollen M.

Biosci Rep. 2015 Oct 2;35(6). pii: e00267. doi: 10.1042/BSR20150194. Erratum in: Biosci Rep. 2018 Nov 30;38(6):.

36.

Automation of High-Throughput Mass Spectrometry-Based Plasma N-Glycome Analysis with Linkage-Specific Sialic Acid Esterification.

Bladergroen MR, Reiding KR, Hipgrave Ederveen AL, Vreeker GC, Clerc F, Holst S, Bondt A, Wuhrer M, van der Burgt YE.

J Proteome Res. 2015 Sep 4;14(9):4080-6. doi: 10.1021/acs.jproteome.5b00538. Epub 2015 Aug 11.

PMID:
26179816
37.

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment.

Lambertz I, Kumps C, Claeys S, Lindner S, Beckers A, Janssens E, Carter DR, Cazes A, Cheung BB, De Mariano M, De Bondt A, De Brouwer S, Delattre O, Gibbons J, Janoueix-Lerosey I, Laureys G, Liang C, Marchall GM, Porcu M, Takita J, Trujillo DC, Van Den Wyngaert I, Van Roy N, Van Goethem A, Van Maerken T, Zabrocki P, Cools J, Schulte JH, Vialard J, Speleman F, De Preter K.

Clin Cancer Res. 2015 Jul 15;21(14):3327-39. doi: 10.1158/1078-0432.CCR-14-2024. Epub 2015 Mar 24.

38.

Immunoglobulin G (IgG) Fab glycosylation analysis using a new mass spectrometric high-throughput profiling method reveals pregnancy-associated changes.

Bondt A, Rombouts Y, Selman MH, Hensbergen PJ, Reiding KR, Hazes JM, Dolhain RJ, Wuhrer M.

Mol Cell Proteomics. 2014 Nov;13(11):3029-39. doi: 10.1074/mcp.M114.039537. Epub 2014 Jul 8.

39.

Improved nonreductive O-glycan release by hydrazinolysis with ethylenediaminetetraacetic acid addition.

Kozak RP, Royle L, Gardner RA, Bondt A, Fernandes DL, Wuhrer M.

Anal Biochem. 2014 May 15;453:29-37. doi: 10.1016/j.ab.2014.02.030. Epub 2014 Mar 5.

PMID:
24613257
40.

Translation of branched-chain aminotransferase-1 transcripts is impaired in cells haploinsufficient for ribosomal protein genes.

Pereboom TC, Bondt A, Pallaki P, Klasson TD, Goos YJ, Essers PB, Groot Koerkamp MJ, Gazda HT, Holstege FC, Costa LD, MacInnes AW.

Exp Hematol. 2014 May;42(5):394-403.e4. doi: 10.1016/j.exphem.2013.12.010. Epub 2014 Jan 23.

PMID:
24463277
41.

Association between galactosylation of immunoglobulin G and improvement of rheumatoid arthritis during pregnancy is independent of sialylation.

Bondt A, Selman MH, Deelder AM, Hazes JM, Willemsen SP, Wuhrer M, Dolhain RJ.

J Proteome Res. 2013 Oct 4;12(10):4522-31. doi: 10.1021/pr400589m. Epub 2013 Sep 24.

PMID:
24016253
42.

Glycoproteomic analysis of antibodies.

Zauner G, Selman MH, Bondt A, Rombouts Y, Blank D, Deelder AM, Wuhrer M.

Mol Cell Proteomics. 2013 Apr;12(4):856-65. doi: 10.1074/mcp.R112.026005. Epub 2013 Jan 16. Review.

43.

Fc specific IgG glycosylation profiling by robust nano-reverse phase HPLC-MS using a sheath-flow ESI sprayer interface.

Selman MH, Derks RJ, Bondt A, Palmblad M, Schoenmaker B, Koeleman CA, van de Geijn FE, Dolhain RJ, Deelder AM, Wuhrer M.

J Proteomics. 2012 Feb 2;75(4):1318-29. doi: 10.1016/j.jprot.2011.11.003. Epub 2011 Nov 15.

PMID:
22120122
44.

A zebrafish model of dyskeratosis congenita reveals hematopoietic stem cell formation failure resulting from ribosomal protein-mediated p53 stabilization.

Pereboom TC, van Weele LJ, Bondt A, MacInnes AW.

Blood. 2011 Nov 17;118(20):5458-65. doi: 10.1182/blood-2011-04-351460. Epub 2011 Sep 14.

PMID:
21921046
45.

cn.FARMS: a latent variable model to detect copy number variations in microarray data with a low false discovery rate.

Clevert DA, Mitterecker A, Mayr A, Klambauer G, Tuefferd M, De Bondt A, Talloen W, Göhlmann H, Hochreiter S.

Nucleic Acids Res. 2011 Jul;39(12):e79. doi: 10.1093/nar/gkr197. Epub 2011 Apr 12.

46.

Microarray profiling of DNA extracted from FFPE tissues using SNP 6.0 Affymetrix platform.

Tuefferd M, de Bondt A, Van den Wyngaert I, Talloen W, Göhlmann H.

Methods Mol Biol. 2011;724:147-60. doi: 10.1007/978-1-61779-055-3_10.

PMID:
21370012
47.

An investigation on performance of Significance Analysis of Microarray (SAM) for the comparisons of several treatments with one control in the presence of small-variance genes.

Lin D, Shkedy Z, Burzykowski T, Ion R, Göhlmann HW, Bondt AD, Perer T, Geerts T, Van den Wyngaert I, Bijnens L.

Biom J. 2008 Oct;50(5):801-23. doi: 10.1002/bimj.200710467.

PMID:
18932139
48.

Genome-wide copy number alterations detection in fresh frozen and matched FFPE samples using SNP 6.0 arrays.

Tuefferd M, De Bondt A, Van Den Wyngaert I, Talloen W, Verbeke T, Carvalho B, Clevert DA, Alifano M, Raghavan N, Amaratunga D, Göhlmann H, Broët P, Camilleri-Broët S.

Genes Chromosomes Cancer. 2008 Nov;47(11):957-64. doi: 10.1002/gcc.20599.

PMID:
18663747
49.

Testing for trends in dose-response microarray experiments: a comparison of several testing procedures, multiplicity and resampling-based inference.

Lin D, Shkedy Z, Yekutieli D, Burzykowski T, Göhlmann HW, De Bondt A, Perera T, Geerts T, Bijnens L.

Stat Appl Genet Mol Biol. 2007;6:Article26. Epub 2007 Oct 11.

PMID:
18052909
50.

The high-level similarity of some disparate gene expression measures.

Raghavan N, De Bondt AM, Talloen W, Moechars D, Göhlmann HW, Amaratunga D.

Bioinformatics. 2007 Nov 15;23(22):3032-8. Epub 2007 Sep 24.

PMID:
17893087

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