Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 22

1.

Imidazolopiperazines Kill both Rings and Dormant Rings in Wild-Type and K13 Artemisinin-Resistant Plasmodium falciparum In Vitro.

Dembele L, Gupta DK, Lim MY, Ang X, Selva JJ, Chotivanich K, Nguon C, Dondorp AM, Bonamy GMC, Diagana TT, Bifani P.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02235-17. doi: 10.1128/AAC.02235-17. Print 2018 May.

2.

Development of a Cytopathic Effect-Based Phenotypic Screening Assay against Cryptosporidium.

Chao AT, Lee BH, Wan KF, Selva J, Zou B, Gedeck P, Beer DJ, Diagana TT, Bonamy GMC, Manjunatha UH.

ACS Infect Dis. 2018 Apr 13;4(4):635-645. doi: 10.1021/acsinfecdis.7b00247. Epub 2018 Jan 25.

PMID:
29341586
3.

A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi.

Voorberg-van der Wel A, Roma G, Gupta DK, Schuierer S, Nigsch F, Carbone W, Zeeman AM, Lee BH, Hofman SO, Faber BW, Knehr J, Pasini E, Kinzel B, Bifani P, Bonamy GMC, Bouwmeester T, Kocken CHM, Diagana TT.

Elife. 2017 Dec 7;6. pii: e29605. doi: 10.7554/eLife.29605.

4.

Identification of SPPL2a Inhibitors by Multiparametric Analysis of a High-Content Ultra-High-Throughput Screen.

Zhang X, Götte M, Ibig-Rehm Y, Schuffenhauer A, Kamke M, Beisner D, Guerini D, Siebert D, Bonamy GMC, Gabriel D, Bodendorf U.

SLAS Discov. 2017 Jul 1:2472555217719834. doi: 10.1177/2472555217719834. [Epub ahead of print]

PMID:
28731783
5.

A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis.

Manjunatha UH, Vinayak S, Zambriski JA, Chao AT, Sy T, Noble CG, Bonamy GMC, Kondreddi RR, Zou B, Gedeck P, Brooks CF, Herbert GT, Sateriale A, Tandel J, Noh S, Lakshminarayana SB, Lim SH, Goodman LB, Bodenreider C, Feng G, Zhang L, Blasco F, Wagner J, Leong FJ, Striepen B, Diagana TT.

Nature. 2017 Jun 15;546(7658):376-380. doi: 10.1038/nature22337. Epub 2017 May 31.

6.

The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites.

Dembele L, Ang X, Chavchich M, Bonamy GMC, Selva JJ, Lim MY, Bodenreider C, Yeung BKS, Nosten F, Russell BM, Edstein MD, Straimer J, Fidock DA, Diagana TT, Bifani P.

Sci Rep. 2017 May 24;7(1):2325. doi: 10.1038/s41598-017-02440-6.

7.

The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase.

Estoppey D, Lee CM, Janoschke M, Lee BH, Wan KF, Dong H, Mathys P, Filipuzzi I, Schuhmann T, Riedl R, Aust T, Galuba O, McAllister G, Russ C, Spiess M, Bouwmeester T, Bonamy GMC, Hoepfner D.

Cell Rep. 2017 Apr 18;19(3):451-460. doi: 10.1016/j.celrep.2017.03.071.

8.

Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit.

Kounde CS, Yeo HQ, Wang QY, Wan KF, Dong H, Karuna R, Dix I, Wagner T, Zou B, Simon O, Bonamy GMC, Yeung BKS, Yokokawa F.

Bioorg Med Chem Lett. 2017 Mar 15;27(6):1385-1389. doi: 10.1016/j.bmcl.2017.02.005. Epub 2017 Feb 4.

PMID:
28216045
9.

The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.

Britschgi A, Duss S, Kim S, Couto JP, Brinkhaus H, Koren S, De Silva D, Mertz KD, Kaup D, Varga Z, Voshol H, Vissieres A, Leroy C, Roloff T, Stadler MB, Scheel CH, Miraglia LJ, Orth AP, Bonamy GM, Reddy VA, Bentires-Alj M.

Nature. 2017 Jan 26;541(7638):541-545. doi: 10.1038/nature20829. Epub 2017 Jan 9.

10.

UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes.

Lim MY, LaMonte G, Lee MCS, Reimer C, Tan BH, Corey V, Tjahjadi BF, Chua A, Nachon M, Wintjens R, Gedeck P, Malleret B, Renia L, Bonamy GMC, Ho PC, Yeung BKS, Chow ED, Lim L, Fidock DA, Diagana TT, Winzeler EA, Bifani P.

Nat Microbiol. 2016 Sep 19;1:16166. doi: 10.1038/nmicrobiol.2016.166.

11.

FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells.

Kim S, Dubrovska A, Salamone RJ, Walker JR, Grandinetti KB, Bonamy GM, Orth AP, Elliott J, Porta DG, Garcia-Echeverria C, Reddy VA.

PLoS One. 2013;8(1):e51671. doi: 10.1371/journal.pone.0051671. Epub 2013 Jan 2.

12.

A small molecule promotes mitochondrial fusion in mammalian cells.

Wang D, Wang J, Bonamy GM, Meeusen S, Brusch RG, Turk C, Yang P, Schultz PG.

Angew Chem Int Ed Engl. 2012 Sep 10;51(37):9302-5. doi: 10.1002/anie.201204589. Epub 2012 Aug 21. No abstract available.

PMID:
22907892
13.

Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP.

Miller E, Yang J, DeRan M, Wu C, Su AI, Bonamy GM, Liu J, Peters EC, Wu X.

Chem Biol. 2012 Aug 24;19(8):955-62. doi: 10.1016/j.chembiol.2012.07.005. Epub 2012 Aug 9.

14.

Cofactors required for TLR7- and TLR9-dependent innate immune responses.

Chiang CY, Engel A, Opaluch AM, Ramos I, Maestre AM, Secundino I, De Jesus PD, Nguyen QT, Welch G, Bonamy GM, Miraglia LJ, Orth AP, Nizet V, Fernandez-Sesma A, Zhou Y, Barton GM, Chanda SK.

Cell Host Microbe. 2012 Mar 15;11(3):306-18. doi: 10.1016/j.chom.2012.02.002.

15.

Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.

Meister S, Plouffe DM, Kuhen KL, Bonamy GM, Wu T, Barnes SW, Bopp SE, Borboa R, Bright AT, Che J, Cohen S, Dharia NV, Gagaring K, Gettayacamin M, Gordon P, Groessl T, Kato N, Lee MC, McNamara CW, Fidock DA, Nagle A, Nam TG, Richmond W, Roland J, Rottmann M, Zhou B, Froissard P, Glynne RJ, Mazier D, Sattabongkot J, Schultz PG, Tuntland T, Walker JR, Zhou Y, Chatterjee A, Diagana TT, Winzeler EA.

Science. 2011 Dec 9;334(6061):1372-7. doi: 10.1126/science.1211936. Epub 2011 Nov 17.

16.

A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor.

Nam TG, McNamara CW, Bopp S, Dharia NV, Meister S, Bonamy GM, Plouffe DM, Kato N, McCormack S, Bursulaya B, Ke H, Vaidya AB, Schultz PG, Winzeler EA.

ACS Chem Biol. 2011 Nov 18;6(11):1214-22. doi: 10.1021/cb200105d. Epub 2011 Sep 8.

17.

Determining the distribution of probes between different subcellular locations through automated unmixing of subcellular patterns.

Peng T, Bonamy GM, Glory-Afshar E, Rines DR, Chanda SK, Murphy RF.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2944-9. doi: 10.1073/pnas.0912090107. Epub 2010 Feb 1.

18.

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

König R, Zhou Y, Elleder D, Diamond TL, Bonamy GM, Irelan JT, Chiang CY, Tu BP, De Jesus PD, Lilley CE, Seidel S, Opaluch AM, Caldwell JS, Weitzman MD, Kuhen KL, Bandyopadhyay S, Ideker T, Orth AP, Miraglia LJ, Bushman FD, Young JA, Chanda SK.

Cell. 2008 Oct 3;135(1):49-60. doi: 10.1016/j.cell.2008.07.032.

19.

Thyroid hormone receptor alpha1 follows a cooperative CRM1/calreticulin-mediated nuclear export pathway.

Grespin ME, Bonamy GM, Roggero VR, Cameron NG, Adam LE, Atchison AP, Fratto VM, Allison LA.

J Biol Chem. 2008 Sep 12;283(37):25576-88. doi: 10.1074/jbc.M710482200. Epub 2008 Jul 19.

20.

Oncogenic conversion of the thyroid hormone receptor by altered nuclear transport.

Bonamy GM, Allison LA.

Nucl Recept Signal. 2006;4:e008. Epub 2006 Apr 28.

21.

Cancer promoted by the oncoprotein v-ErbA may be due to subcellular mislocalization of nuclear receptors.

Bonamy GM, Guiochon-Mantel A, Allison LA.

Mol Endocrinol. 2005 May;19(5):1213-30. Epub 2005 Jan 13. Erratum in: Mol Endocrinol. 2005 Aug;19(8):2085.

PMID:
15650025
22.

Nuclear export of the oncoprotein v-ErbA is mediated by acquisition of a viral nuclear export sequence.

DeLong LJ, Bonamy GM, Fink EN, Allison LA.

J Biol Chem. 2004 Apr 9;279(15):15356-67. Epub 2004 Jan 16.

Supplemental Content

Loading ...
Support Center