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Items: 18


The Codon 72 TP53 Polymorphism Contributes to TSC Tumorigenesis through the Notch-Nodal Axis.

Cho JH, Patel B, Bonala S, Mansouri H, Manne S, Vadrevu SK, Ghouse S, Kung CP, Murphy ME, Astrinidis A, Henske EP, Kwiatkowski DJ, Markiewski MM, Karbowniczek M.

Mol Cancer Res. 2019 Aug;17(8):1639-1651. doi: 10.1158/1541-7786.MCR-18-1292. Epub 2019 May 14.


Notch transactivates Rheb to maintain the multipotency of TSC-null cells.

Cho JH, Patel B, Bonala S, Manne S, Zhou Y, Vadrevu SK, Patel J, Peronaci M, Ghouse S, Henske EP, Roegiers F, Giannikou K, Kwiatkowski DJ, Mansouri H, Markiewski MM, White B, Karbowniczek M.

Nat Commun. 2017 Nov 29;8(1):1848. doi: 10.1038/s41467-017-01845-1.


Repeatability of Spectral Domain Optical Coherence Tomography Measurements in High Myopia.

Rao HL, Kumar AU, Bonala SR, Yogesh K, Lakshmi B.

J Glaucoma. 2016 May;25(5):e526-30. doi: 10.1097/IJG.0000000000000385.


Exosomes mediate the acquisition of the disease phenotypes by cells with normal genome in tuberous sclerosis complex.

Patel B, Patel J, Cho JH, Manne S, Bonala S, Henske E, Roegiers F, Markiewski M, Karbowniczek M.

Oncogene. 2016 Jun 9;35(23):3027-36. doi: 10.1038/onc.2015.358. Epub 2015 Oct 5.


Myostatin: expanding horizons.

Sharma M, McFarlane C, Kambadur R, Kukreti H, Bonala S, Srinivasan S.

IUBMB Life. 2015 Aug;67(8):589-600. doi: 10.1002/iub.1392. Epub 2015 Aug 25. Review.


Inactivation of PPARβ/δ adversely affects satellite cells and reduces postnatal myogenesis.

Chandrashekar P, Manickam R, Ge X, Bonala S, McFarlane C, Sharma M, Wahli W, Kambadur R.

Am J Physiol Endocrinol Metab. 2015 Jul 15;309(2):E122-31. doi: 10.1152/ajpendo.00586.2014. Epub 2015 Apr 28.


1) Myostatin is a novel tumoral factor that induces cancer cachexia.

Lokireddy S, Wijesoma IW, Bonala S, Wei M, Sze SK, McFarlane C, Kambadur R, Sharma M.

Biochem J. 2015 Feb 15;466(1):201. No abstract available.


Negative auto-regulation of myostatin expression is mediated by Smad3 and microRNA-27.

McFarlane C, Vajjala A, Arigela H, Lokireddy S, Ge X, Bonala S, Manickam R, Kambadur R, Sharma M.

PLoS One. 2014 Jan 31;9(1):e87687. doi: 10.1371/journal.pone.0087687. eCollection 2014.


Myostatin induces insulin resistance via Casitas B-lineage lymphoma b (Cblb)-mediated degradation of insulin receptor substrate 1 (IRS1) protein in response to high calorie diet intake.

Bonala S, Lokireddy S, McFarlane C, Patnam S, Sharma M, Kambadur R.

J Biol Chem. 2014 Mar 14;289(11):7654-70. doi: 10.1074/jbc.M113.529925. Epub 2014 Jan 22. Retraction in: J Biol Chem. 2016 Jul 1;291(27):14392.


Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity.

Bonala S, McFarlane C, Ang J, Lim R, Lee M, Chua H, Lokireddy S, Sreekanth P, Leow MK, Meng KC, Shyong TE, Lee YS, Gluckman PD, Sharma M, Kambadur R.

Mol Endocrinol. 2013 Sep;27(9):1518-35. doi: 10.1210/me.2013-1048. Epub 2013 Aug 8. Erratum in: Mol Endocrinol. 2015 Jan;29(1):153. Retraction in: Mol Endocrinol. 2016 Aug;30(8):949.


Muscle-specific microRNA1 (miR1) targets heat shock protein 70 (HSP70) during dexamethasone-mediated atrophy.

Kukreti H, Amuthavalli K, Harikumar A, Sathiyamoorthy S, Feng PZ, Anantharaj R, Tan SL, Lokireddy S, Bonala S, Sriram S, McFarlane C, Kambadur R, Sharma M.

J Biol Chem. 2013 Mar 1;288(9):6663-78. doi: 10.1074/jbc.M112.390369. Epub 2013 Jan 6.


The ubiquitin ligase Mul1 induces mitophagy in skeletal muscle in response to muscle-wasting stimuli.

Lokireddy S, Wijesoma IW, Teng S, Bonala S, Gluckman PD, McFarlane C, Sharma M, Kambadur R.

Cell Metab. 2012 Nov 7;16(5):613-24. doi: 10.1016/j.cmet.2012.10.005. Retraction in: Cell Metab. 2015 Dec 1;22(6):1090.


Myostatin is a novel tumoral factor that induces cancer cachexia.

Lokireddy S, Wijesoma IW, Bonala S, Wei M, Sze SK, McFarlane C, Kambadur R, Sharma M.

Biochem J. 2012 Aug 15;446(1):23-36. doi: 10.1042/BJ20112024. Erratum in: Biochem J. 2015 Feb 15;466(1):201. Retraction in: Lokireddy S, Wijesoma IW, Bonala S, Wei M, Sze SK, McFarlane C, Kambadur R, Sharma M. Biochem J. 2016 Apr 15;473(8):1111.


Peroxisome proliferator-activated receptor β/δ induces myogenesis by modulating myostatin activity.

Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R.

J Biol Chem. 2012 Apr 13;287(16):12935-51. doi: 10.1074/jbc.M111.319145. Epub 2012 Feb 23. Retraction in: J Biol Chem. 2016 Jul 1;291(27):14391.


Myostatin-deficient mice exhibit reduced insulin resistance through activating the AMP-activated protein kinase signalling pathway.

Zhang C, McFarlane C, Lokireddy S, Bonala S, Ge X, Masuda S, Gluckman PD, Sharma M, Kambadur R.

Diabetologia. 2011 Jun;54(6):1491-501. doi: 10.1007/s00125-011-2079-7. Epub 2011 Feb 24. Erratum in: Diabetologia. 2015 Mar;58(3):643.


Asthma severity, psychiatric morbidity, and quality of life: correlation with inhaled corticosteroid dose.

Bonala SB, Pina D, Silverman BA, Amara S, Bassett CW, Schneider AT.

J Asthma. 2003 Sep;40(6):691-9.


Bone mineral density in women with asthma on long-term inhaled corticosteroid therapy.

Bonala SB, Reddy BM, Silverman BA, Bassett CW, Rao YA, Amara S, Schneider AT.

Ann Allergy Asthma Immunol. 2000 Dec;85(6 Pt 1):495-500.


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