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Items: 1 to 50 of 132

1.

Hypoglycemic and Hypolipemic Effects of a New Lecithin Formulation of Bergamot Polyphenolic Fraction: A Double Blind, Randomized, Placebo- Controlled Study.

Mollace V, Scicchitano M, Paone S, Casale F, Calandruccio C, Gliozzi M, Musolino V, Carresi C, Maiuolo J, Nucera S, Riva A, Allegrini P, Ronchi M, Petrangolini G, Bombardelli E.

Endocr Metab Immune Disord Drug Targets. 2019;19(2):136-143. doi: 10.2174/1871530319666181203151513.

PMID:
30501605
2.
3.

The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial.

Giacosa A, Guido D, Grassi M, Riva A, Morazzoni P, Bombardelli E, Perna S, Faliva MA, Rondanelli M.

Evid Based Complement Alternat Med. 2015;2015:915087. doi: 10.1155/2015/915087. Epub 2015 Apr 14.

4.

Can nausea and vomiting be treated with ginger extract?

Giacosa A, Morazzoni P, Bombardelli E, Riva A, Bianchi Porro G, Rondanelli M.

Eur Rev Med Pharmacol Sci. 2015 Apr;19(7):1291-6. Review.

5.

Anticancer and Antibacterial Activity of Hyperforin and Its Derivatives.

Pia Schiavone BI, Verotta L, Rosato A, Marilena M, Gibbons S, Bombardelli E, Franchini C, Corbo F.

Anticancer Agents Med Chem. 2014;14(10):1397-1401. Review.

PMID:
25173557
6.

Effect of SAMITAL® in the treatment of chemotherapy-induced mucositis in adult oncohematological patients.

Bertoglio JC, Calderón S, Lesina B, Pilleux L, Morazzoni P, Riva A, Bombardelli E, Ronchi M, Cabri W, Petrangolini G.

Future Oncol. 2013 Nov;9(11):1727-32. doi: 10.2217/fon.13.164.

PMID:
24156332
7.

SAMITAL®: a new botanical drug for the treatment of mucositis induced by oncological therapies.

Morazzoni P, Petrangolini G, Bombardelli E, Ronchi M, Cabri W, Riva A.

Future Oncol. 2013 Nov;9(11):1717-25. doi: 10.2217/fon.13.165. Review.

PMID:
24156331
8.

Biological evaluation of hyperforin and its hydrogenated analogue on bacterial growth and biofilm production.

Schiavone BI, Rosato A, Marilena M, Gibbons S, Bombardelli E, Verotta L, Franchini C, Corbo F.

J Nat Prod. 2013 Sep 27;76(9):1819-23. doi: 10.1021/np400394c. Epub 2013 Aug 27.

PMID:
23981190
9.

Metabolic management in overweight subjects with naive impaired fasting glycaemia by means of a highly standardized extract from Cynara scolymus: a double-blind, placebo-controlled, randomized clinical trial.

Rondanelli M, Opizzi A, Faliva M, Sala P, Perna S, Riva A, Morazzoni P, Bombardelli E, Giacosa A.

Phytother Res. 2014 Jan;28(1):33-41. doi: 10.1002/ptr.4950. Epub 2013 Feb 25.

PMID:
23440660
10.

Reducing effect of an extract of Phaseolus vulgaris on food intake in mice--focus on highly palatable foods.

Loi B, Fantini N, Colombo G, Gessa GL, Riva A, Bombardelli E, Morazzoni P, Carai MA.

Fitoterapia. 2013 Mar;85:14-9. doi: 10.1016/j.fitote.2012.12.015. Epub 2012 Dec 20.

PMID:
23262270
11.

Management of gastrointestinal mucositis due to cancer therapies in pediatric patients: results of a case series with SAMITAL(®).

Bertoglio JC, Folatre I, Bombardelli E, Riva A, Morazzoni P, Ronchi M, Petrangolini G.

Future Oncol. 2012 Nov;8(11):1481-6. doi: 10.2217/fon.12.132.

PMID:
23148620
12.

SAMITAL® improves chemo/radiotherapy-induced oral mucositis in patients with head and neck cancer: results of a randomized, placebo-controlled, single-blind Phase II study.

Pawar D, Neve RS, Kalgane S, Riva A, Bombardelli E, Ronchi M, Petrangolini G, Morazzoni P.

Support Care Cancer. 2013 Mar;21(3):827-34. doi: 10.1007/s00520-012-1586-5. Epub 2012 Sep 4.

PMID:
22945882
13.

Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on operant self-administration of a chocolate-flavoured beverage in rats.

Zaru A, Maccioni P, Riva A, Morazzoni P, Bombardelli E, Gessa GL, Carai MA, Colombo G.

Phytother Res. 2013 Jun;27(6):944-7. doi: 10.1002/ptr.4814. Epub 2012 Aug 17.

PMID:
22899449
14.

Beneficial effects of artichoke leaf extract supplementation on increasing HDL-cholesterol in subjects with primary mild hypercholesterolaemia: a double-blind, randomized, placebo-controlled trial.

Rondanelli M, Giacosa A, Opizzi A, Faliva MA, Sala P, Perna S, Riva A, Morazzoni P, Bombardelli E.

Int J Food Sci Nutr. 2013 Feb;64(1):7-15. doi: 10.3109/09637486.2012.700920. Epub 2012 Jun 29.

PMID:
22746542
15.

Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on food intake and glycemia in rats.

Loi B, Fantini N, Colombo G, Gessa GL, Riva A, Bombardelli E, Morazzoni P, Carai MA.

Phytother Res. 2013 Feb;27(2):258-63. doi: 10.1002/ptr.4704. Epub 2012 May 8.

PMID:
22565861
16.

Bacterial biofilm formation inhibitory activity revealed for plant derived natural compounds.

Artini M, Papa R, Barbato G, Scoarughi GL, Cellini A, Morazzoni P, Bombardelli E, Selan L.

Bioorg Med Chem. 2012 Jan 15;20(2):920-6. doi: 10.1016/j.bmc.2011.11.052. Epub 2011 Dec 1.

PMID:
22182580
17.

Inhibition of viral RNA synthesis in canine distemper virus infection by proanthocyanidin A2.

Gallina L, Dal Pozzo F, Galligioni V, Bombardelli E, Scagliarini A.

Antiviral Res. 2011 Dec;92(3):447-52. doi: 10.1016/j.antiviral.2011.10.004. Epub 2011 Oct 13.

PMID:
22020306
18.
19.

Multiple cycles of repeated treatments with a Phaseolus vulgaris dry extract reduce food intake and body weight in obese rats.

Carai MA, Fantini N, Loi B, Colombo G, Gessa GL, Riva A, Bombardelli E, Morazzoni P.

Br J Nutr. 2011 Sep;106(5):762-8. doi: 10.1017/S0007114511000778. Epub 2011 May 3.

PMID:
21535904
20.

Structure-activity relationship study of 16 a-thiocamptothecins: an integrated in vitro and in silico approach.

Samorì C, Beretta GL, Varchi G, Guerrini A, Di Micco S, Basili S, Bifulco G, Riccio R, Moro S, Bombardelli E, Zunino F, Fontana G.

ChemMedChem. 2010 Dec 3;5(12):2006-15. doi: 10.1002/cmdc.201000369.

PMID:
21069656
21.

Evidence of glycemia-lowering effect by a Cynara scolymus L. extract in normal and obese rats.

Fantini N, Colombo G, Giori A, Riva A, Morazzoni P, Bombardelli E, Carai MA.

Phytother Res. 2011 Mar;25(3):463-6. doi: 10.1002/ptr.3285. Epub 2010 Aug 25.

PMID:
20737658
22.

Mirtogenol potentiates latanoprost in lowering intraocular pressure and improves ocular blood flow in asymptomatic subjects.

Steigerwalt RD Jr, Belcaro G, Morazzoni P, Bombardelli E, Burki C, Schönlau F.

Clin Ophthalmol. 2010 May 14;4:471-6.

23.

Reducing effect of a Phaseolus vulgaris dry extract on operant self-administration of a chocolate-flavoured beverage in rats.

Maccioni P, Colombo G, Riva A, Morazzoni P, Bombardelli E, Gessa GL, Carai MA.

Br J Nutr. 2010 Sep;104(5):624-8. doi: 10.1017/S0007114510001017. Epub 2010 Mar 26.

PMID:
20338076
24.

Tetrahydrohyperforin and octahydrohyperforin are two new potent inhibitors of angiogenesis.

Martínez-Poveda B, Verotta L, Bombardelli E, Quesada AR, Medina MA.

PLoS One. 2010 Mar 9;5(3):e9558. doi: 10.1371/journal.pone.0009558.

25.

The hyperforin derivative IDN5706 occludes spatial memory impairments and neuropathological changes in a double transgenic Alzheimer's mouse model.

Cerpa W, Hancke JL, Morazzoni P, Bombardelli E, Riva A, Marin PP, Inestrosa NC.

Curr Alzheimer Res. 2010 Mar;7(2):126-33.

PMID:
19939230
26.

Reducing effect of a Phaseolus vulgaris dry extract on food intake, body weight, and glycemia in rats.

Fantini N, Cabras C, Lobina C, Colombo G, Gessa GL, Riva A, Donzelli F, Morazzoni P, Bombardelli E, Carai MA.

J Agric Food Chem. 2009 Oct 14;57(19):9316-23. doi: 10.1021/jf900711z.

PMID:
19731962
27.

Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins.

Samorì C, Guerrini A, Varchi G, Fontana G, Bombardelli E, Tinelli S, Beretta GL, Basili S, Moro S, Zunino F, Battaglia A.

J Med Chem. 2009 Feb 26;52(4):1029-39. doi: 10.1021/jm801153y.

PMID:
19530720
28.

Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin.

Pepe A, Sun L, Zanardi I, Wu X, Ferlini C, Fontana G, Bombardelli E, Ojima I.

Bioorg Med Chem Lett. 2009 Jun 15;19(12):3300-4. doi: 10.1016/j.bmcl.2009.04.070. Epub 2009 Apr 22.

29.

The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates.

Samorì C, Guerrini A, Varchi G, Beretta GL, Fontana G, Bombardelli E, Carenini N, Zunino F, Bertucci C, Fiori J, Battaglia A.

Bioconjug Chem. 2008 Nov 19;19(11):2270-9. doi: 10.1021/bc800033r. Erratum in: Bioconjug Chem. 2009 Mar 18;20(3):629. Samor, Cristian [corrected to Samorì, Cristian].

PMID:
18839979
30.

Green tea catechins in chemoprevention of cancer: a molecular docking investigation into their interaction with glutathione S-transferase (GST P1-1).

Artali R, Beretta G, Morazzoni P, Bombardelli E, Meneghetti F.

J Enzyme Inhib Med Chem. 2009 Feb;24(1):287-95. doi: 10.1080/14756360802177282 .

PMID:
18825537
31.

Effects of Mirtogenol on ocular blood flow and intraocular hypertension in asymptomatic subjects.

Steigerwalt RD, Gianni B, Paolo M, Bombardelli E, Burki C, Schönlau F.

Mol Vis. 2008 Jul 10;14:1288-92.

32.

The protection of polyunsaturated fatty acids in micellar systems against UVB-induced photo-oxidation by procyanidins from Vitis vinifera L., and the protective synergy with vitamin E.

Carini M, Maffei Facino R, Aldini G, Callonii MT, Bombardelli E, Morazzoni P.

Int J Cosmet Sci. 1998 Aug;20(4):203-15. doi: 10.1046/j.1467-2494.1998.176606.x.

PMID:
18505504
33.

Thiocamptothecin.

Samorì C, Guerrini A, Varchi G, Zunino F, Beretta GL, Femoni C, Bombardelli E, Fontana G, Battaglia A.

J Med Chem. 2008 May 22;51(10):3040-4. doi: 10.1021/jm8001982. Epub 2008 Apr 18.

PMID:
18419110
34.

Novel 3-O-glycosyl-3-demethylthiocolchicines as ligands for glycine and gamma-aminobutyric acid receptors.

Gelmi ML, Fontana G, Pocar D, Pontremoli G, Pellegrino S, Bombardelli E, Riva A, Balduini W, Carloni S, Cimino M.

J Med Chem. 2007 May 3;50(9):2245-8. Epub 2007 Apr 6.

PMID:
17411024
35.

Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J.

Botta M, Armaroli S, Castagnolo D, Fontana G, Pera P, Bombardelli E.

Bioorg Med Chem Lett. 2007 Mar 15;17(6):1579-83. Epub 2007 Jan 8.

PMID:
17254787
36.

In vitro antimalarial activity of hyperforin, a prenylated acylphloroglucinol. A structure-activity study.

Verotta L, Appendino G, Bombardelli E, Brun R.

Bioorg Med Chem Lett. 2007 Mar 15;17(6):1544-8. Epub 2007 Jan 8.

PMID:
17234416
37.

Synthesis and biological evaluation of paclitaxel-thiocolchicine hybrids.

Danieli B, Giardini A, Lesma G, Passarella D, Silvani A, Appendino G, Noncovich A, Fontana G, Bombardelli E, Sterner O.

Chem Biodivers. 2004 Feb;1(2):327-45.

PMID:
17191851
38.

Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.

Beretta GL, Petrangolini G, De Cesare M, Pratesi G, Perego P, Tinelli S, Tortoreto M, Zucchetti M, Frapolli R, Bello E, Manzotti C, Fontana G, Bombardelli E, Battaglia A, Samorì C, Zunino F.

Cancer Res. 2006 Nov 15;66(22):10976-82.

39.

3-demethoxy-3-glycosylaminothiocolchicines: Synthesis of a new class of putative muscle relaxant compounds.

Gelmi ML, Pocar D, Pontremoli G, Pellegrino S, Bombardelli E, Fontana G, Riva A, Balduini W, Carloni S, Cimino M, Johnson F.

J Med Chem. 2006 Sep 7;49(18):5571-7.

PMID:
16942030
40.

Identification of miltirone as active ingredient of Salvia miltiorrhiza responsible for the reducing effect of root extracts on alcohol intake in rats.

Colombo G, Serra S, Vacca G, Orrù A, Maccioni P, Morazzoni P, Bombardelli E, Riva A, Gessa GL, Carai MA.

Alcohol Clin Exp Res. 2006 May;30(5):754-62.

PMID:
16634843
41.

Estradiol and phytoestrogens differently influence the rodent postmenopausal mammary gland.

Gallo D, Zannoni GF, Martinelli E, Ferlini C, Fabrizi M, Riva A, Morazzoni P, Bombardelli E, Scambia G.

Menopause. 2006 Jan-Feb;13(1):72-9.

PMID:
16607101
42.

LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.

Mauri P, De Palma A, Pozzi F, Basilico F, Riva A, Morazzoni P, Bombardelli E, Rossoni G.

J Pharm Biomed Anal. 2006 Feb 24;40(3):763-8. Epub 2005 Dec 15.

PMID:
16343838
43.

Synthesis of deserpidine from reserpine.

Varchi G, Battaglia A, Samorì C, Baldelli E, Danieli B, Fontana G, Guerrini A, Bombardelli E.

J Nat Prod. 2005 Nov;68(11):1629-31.

PMID:
16309312
44.

Pharmacokinetic measurements of IDN 5390 using electrospray ionization tandem mass spectrometry: structure characterization and quantification in dog plasma.

Song L, Prey JD, Xue J, Kanter P, Manzotti C, Bombardelli E, Morazzoni P, Pendyala L.

Rapid Commun Mass Spectrom. 2005;19(24):3617-25.

PMID:
16299696
45.

Synthesis and biological evaluation of methoxylated analogs of the newer generation taxoids IDN5109 and IDN5390.

Barboni L, Ballini R, Giarlo G, Appendino G, Fontana G, Bombardelli E.

Bioorg Med Chem Lett. 2005 Dec 1;15(23):5182-6. Epub 2005 Sep 23.

PMID:
16183281
46.

Characterization of the pharmacologic profile of a standardized soy extract in the ovariectomized rat model of menopause: effects on bone, uterus, and lipid profile.

Gallo D, Zannoni GF, Apollonio P, Martinelli E, Ferlini C, Passetti G, Riva A, Morazzoni P, Bombardelli E, Scambia G.

Menopause. 2005 Sep-Oct;12(5):589-600. Epub 2005 Sep 1.

PMID:
16145313
47.

Molecular biology and the staging of prostate cancer.

Marandola P, Bonghi A, Jallous H, Bombardelli E, Morazzoni P, Gerardini M, Tiscione D, Albergati F.

Ann N Y Acad Sci. 2004 Dec;1028:294-312. Review.

PMID:
15650255
48.

Modulation of chemoselectivity by protein additives. Remarkable effects in the oxidation of hyperforin.

Verotta L, Lovaglio E, Sterner O, Appendino G, Bombardelli E.

J Org Chem. 2004 Nov 12;69(23):7869-74.

PMID:
15527263
49.

4-Alkyl- and 4-phenylcoumarins from Mesua ferrea as promising multidrug resistant antibacterials.

Verotta L, Lovaglio E, Vidari G, Finzi PV, Neri MG, Raimondi A, Parapini S, Taramelli D, Riva A, Bombardelli E.

Phytochemistry. 2004 Nov;65(21):2867-79.

PMID:
15501254
50.

New taxane derivatives: synthesis of baccatin[14,1-d]furan-2-one nucleus and its condensation with the norstatine side chain.

Baldelli E, Battaglia A, Bombardelli E, Carenzi G, Fontana G, Gelmi ML, Guerrini A, Pocar D.

J Org Chem. 2004 Oct 1;69(20):6610-6.

PMID:
15387582

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