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Items: 1 to 50 of 76

1.

Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-positive AML Defines Novel Therapeutic Options - A COG and TARGET Pediatric AML Study.

Smith JL, Ries RE, Hylkema T, Alonzo TA, Gerbing RB, Santaguida MT, Eidenschink Brodersen L, Pardo L, Cummings CL, Loeb KR, Le Q, Imren S, Leonti AR, Gamis AS, Aplenc R, Kolb EA, Farrar JE, Triche TJ, Nguyen C, Meerzaman D, Loken MR, Oehler VG, Bolouri H, Meshinchi S.

Clin Cancer Res. 2019 Nov 12. pii: clincanres.1800.2019. doi: 10.1158/1078-0432.CCR-19-1800. [Epub ahead of print]

PMID:
31719049
2.

Genomic distinctions between metastatic lower and upper tract urothelial carcinoma revealed through rapid autopsy.

Winters BR, De Sarkar N, Arora S, Bolouri H, Jana S, Vakar-Lopez F, Cheng HH, Schweizer MT, Yu EY, Grivas P, Lee JK, Kollath L, Holt SK, McFerrin L, Ha G, Nelson PS, Montgomery RB, Wright JL, Lam HM, Hsieh AC.

JCI Insight. 2019 May 30;5. pii: 128728. doi: 10.1172/jci.insight.128728.

3.

Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions.

Bolouri H, Farrar JE, Triche T Jr, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, Davidsen TM, Gesuwan P, Hermida LC, Salhia B, Capone S, Ramsingh G, Zwaan CM, Noort S, Piccolo SR, Kolb EA, Gamis AS, Smith MA, Gerhard DS, Meshinchi S.

Nat Med. 2019 Mar;25(3):530. doi: 10.1038/s41591-019-0369-7.

PMID:
30705421
4.

Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition.

Jia D, Augert A, Kim DW, Eastwood E, Wu N, Ibrahim AH, Kim KB, Dunn CT, Pillai SPS, Gazdar AF, Bolouri H, Park KS, MacPherson D.

Cancer Discov. 2018 Nov;8(11):1422-1437. doi: 10.1158/2159-8290.CD-18-0385. Epub 2018 Sep 4.

5.

Analysis and visualization of linked molecular and clinical cancer data by using Oncoscape.

McFerrin LG, Zager M, Zhang J, Krenn G, McDermott R, Horse-Grant D, Silgard E, Colevas K, Shannon P, Bolouri H, Holland EC.

Nat Genet. 2018 Sep;50(9):1203-1204. doi: 10.1038/s41588-018-0208-7. No abstract available.

PMID:
30158685
6.

Copy number profiling across glioblastoma populations has implications for clinical trial design.

Cimino PJ, McFerrin L, Wirsching HG, Arora S, Bolouri H, Rabadan R, Weller M, Holland EC.

Neuro Oncol. 2018 Sep 3;20(10):1368-1373. doi: 10.1093/neuonc/noy108.

7.

A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.

Ozawa T, Arora S, Szulzewsky F, Juric-Sekhar G, Miyajima Y, Bolouri H, Yasui Y, Barber J, Kupp R, Dalton J, Jones TS, Nakada M, Kumabe T, Ellison DW, Gilbertson RJ, Holland EC.

Cell Rep. 2018 Jun 26;23(13):3787-3797. doi: 10.1016/j.celrep.2018.04.099.

8.

Erratum: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions.

Bolouri H, Farrar JE, Triche T Jr, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, Davidsen TM, Gesuwan P, Hermida LC, Salhia B, Capone S, Ramsingh G, Zwaan CM, Noort S, Piccolo SR, Kolb EA, Gamis AS, Smith MA, Gerhard DS, Meshinchi S.

Nat Med. 2018 Apr 10;24(4):526. doi: 10.1038/nm0418-526b.

PMID:
29634680
9.

The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions.

Bolouri H, Farrar JE, Triche T Jr, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, Davidsen TM, Gesuwan P, Hermida LC, Salhia B, Capone S, Ramsingh G, Zwaan CM, Noort S, Piccolo SR, Kolb EA, Gamis AS, Smith MA, Gerhard DS, Meshinchi S.

Nat Med. 2018 Jan;24(1):103-112. doi: 10.1038/nm.4439. Epub 2017 Dec 11. Erratum in: Nat Med. 2018 Apr 10;24(4):526. Nat Med. 2019 Mar;25(3):530.

10.

Building and validating a prediction model for paediatric type 1 diabetes risk using next generation targeted sequencing of class II HLA genes.

Zhao LP, Carlsson A, Larsson HE, Forsander G, Ivarsson SA, Kockum I, Ludvigsson J, Marcus C, Persson M, Samuelsson U, Örtqvist E, Pyo CW, Bolouri H, Zhao M, Nelson WC, Geraghty DE, Lernmark Å; Better Diabetes Diagnosis (BDD) Study Group.

Diabetes Metab Res Rev. 2017 Nov;33(8). doi: 10.1002/dmrr.2921. Epub 2017 Sep 15. Erratum in: Diabetes Metab Res Rev. 2018 Feb;34(2):.

PMID:
28755385
11.

Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery.

Cimino PJ, Zager M, McFerrin L, Wirsching HG, Bolouri H, Hentschel B, von Deimling A, Jones D, Reifenberger G, Weller M, Holland EC.

Acta Neuropathol Commun. 2017 May 22;5(1):39. doi: 10.1186/s40478-017-0443-7.

12.

Mutant IDH1 regulates the tumor-associated immune system in gliomas.

Amankulor NM, Kim Y, Arora S, Kargl J, Szulzewsky F, Hanke M, Margineantu DH, Rao A, Bolouri H, Delrow J, Hockenbery D, Houghton AM, Holland EC.

Genes Dev. 2017 Apr 15;31(8):774-786. doi: 10.1101/gad.294991.116. Epub 2017 May 2.

13.

miR-155 expression and correlation with clinical outcome in pediatric AML: A report from Children's Oncology Group.

Ramamurthy R, Hughes M, Morris V, Bolouri H, Gerbing RB, Wang YC, Loken MR, Raimondi SC, Hirsch BA, Gamis AS, Oehler VG, Alonzo TA, Meshinchi S.

Pediatr Blood Cancer. 2016 Dec;63(12):2096-2103. doi: 10.1002/pbc.26157. Epub 2016 Aug 11.

14.

Big data visualization identifies the multidimensional molecular landscape of human gliomas.

Bolouri H, Zhao LP, Holland EC.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):5394-9. doi: 10.1073/pnas.1601591113. Epub 2016 Apr 26.

15.

An Object-Oriented Regression for Building Disease Predictive Models with Multiallelic HLA Genes.

Zhao LP, Bolouri H, Zhao M, Geraghty DE, Lernmark Å; Better Diabetes Diagnosis Study Group.

Genet Epidemiol. 2016 May;40(4):315-32. doi: 10.1002/gepi.21968.

16.

Object-oriented regression for building predictive models with high dimensional omics data from translational studies.

Zhao LP, Bolouri H.

J Biomed Inform. 2016 Apr;60:431-45. doi: 10.1016/j.jbi.2016.03.001. Epub 2016 Mar 10.

17.

Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer.

Kumar A, Coleman I, Morrissey C, Zhang X, True LD, Gulati R, Etzioni R, Bolouri H, Montgomery B, White T, Lucas JM, Brown LG, Dumpit RF, DeSarkar N, Higano C, Yu EY, Coleman R, Schultz N, Fang M, Lange PH, Shendure J, Vessella RL, Nelson PS.

Nat Med. 2016 Apr;22(4):369-78. doi: 10.1038/nm.4053. Epub 2016 Feb 29.

18.

Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.

Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H, Davison J, Zhang Q, Hardcastle J, Aronow BJ, Plaisier CL, Baliga NS, Moffat J, Lin Q, Li XN, Nam DH, Lee J, Pollard SM, Zhu J, Delrow JJ, Clurman BE, Olson JM, Paddison PJ.

Cell Rep. 2015 Dec 22;13(11):2425-2439. doi: 10.1016/j.celrep.2015.11.021. Epub 2015 Dec 7.

19.

Animal Models for Concussion: Molecular and Cognitive Assessments—Relevance to Sport and Military Concussions.

Bolouri H, Zetterberg H.

In: Kobeissy FH, editor. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects. Boca Raton (FL): CRC Press/Taylor & Francis; 2015. Chapter 46.

20.

ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.

Nguyen LT, Tretiakova MS, Silvis MR, Lucas J, Klezovitch O, Coleman I, Bolouri H, Kutyavin VI, Morrissey C, True LD, Nelson PS, Vasioukhin V.

Cancer Cell. 2015 Jun 8;27(6):797-808. doi: 10.1016/j.ccell.2015.05.005.

21.

Oncogenic signaling is dominant to cell of origin and dictates astrocytic or oligodendroglial tumor development from oligodendrocyte precursor cells.

Lindberg N, Jiang Y, Xie Y, Bolouri H, Kastemar M, Olofsson T, Holland EC, Uhrbom L.

J Neurosci. 2014 Oct 29;34(44):14644-51. doi: 10.1523/JNEUROSCI.2977-14.2014.

22.

Modeling genomic regulatory networks with big data.

Bolouri H.

Trends Genet. 2014 May;30(5):182-91. doi: 10.1016/j.tig.2014.02.005. Epub 2014 Mar 13. Review.

PMID:
24630831
23.

Network dynamics in the tumor microenvironment.

Bolouri H.

Semin Cancer Biol. 2015 Feb;30:52-9. doi: 10.1016/j.semcancer.2014.02.007. Epub 2014 Feb 25. Review.

PMID:
24582766
24.

Innate defense regulator peptide 1018 protects against perinatal brain injury.

Bolouri H, Sävman K, Wang W, Thomas A, Maurer N, Dullaghan E, Fjell CD, Ek CJ, Hagberg H, Hancock RE, Brown KL, Mallard C.

Ann Neurol. 2014 Mar;75(3):395-410. doi: 10.1002/ana.24087. Epub 2014 Mar 7.

PMID:
24339166
25.

Radixin expression in microglia after cortical stroke lesion.

Persson Å, Osman A, Bolouri H, Mallard C, Kuhn HG.

Glia. 2013 May;61(5):790-9. doi: 10.1002/glia.22473. Epub 2013 Feb 26.

PMID:
23440885
26.

Integration of 198 ChIP-seq datasets reveals human cis-regulatory regions.

Bolouri H, Ruzzo WL.

J Comput Biol. 2012 Sep;19(9):989-97. doi: 10.1089/cmb.2012.0100. Epub 2012 Aug 16.

PMID:
22897152
27.

Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury.

Keller M, Enot DP, Hodson MP, Igwe EI, Deigner HP, Dean J, Bolouri H, Hagberg H, Mallard C.

PLoS One. 2011;6(12):e29503. doi: 10.1371/journal.pone.0029503. Epub 2011 Dec 29.

28.

Animal model for sport-related concussion; ICP and cognitive function.

Bolouri H, Säljö A, Viano DC, Hamberger A.

Acta Neurol Scand. 2012 Apr;125(4):241-7. doi: 10.1111/j.1600-0404.2011.01614.x. Epub 2011 Oct 29.

PMID:
22034961
29.

Evaluation of three animal models for concussion and serious brain injury.

Viano DC, Hamberger A, Bolouri H, Säljö A.

Ann Biomed Eng. 2012 Jan;40(1):213-26. doi: 10.1007/s10439-011-0386-2. Epub 2011 Oct 20.

PMID:
22012080
30.

Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep.

Dean JM, van de Looij Y, Sizonenko SV, Lodygensky GA, Lazeyras F, Bolouri H, Kjellmer I, Huppi PS, Hagberg H, Mallard C.

Ann Neurol. 2011 Nov;70(5):846-56. doi: 10.1002/ana.22480. Epub 2011 Oct 14.

PMID:
22002627
31.

Menu-driven cloud computing and resource sharing for R and Bioconductor.

Bolouri H, Dulepet R, Angerman M.

Bioinformatics. 2011 Aug 15;27(16):2309-10. doi: 10.1093/bioinformatics/btr364. Epub 2011 Jun 17.

32.

Mechanisms and pathophysiology of the low-level blast brain injury in animal models.

Säljö A, Mayorga M, Bolouri H, Svensson B, Hamberger A.

Neuroimage. 2011 Jan;54 Suppl 1:S83-8. doi: 10.1016/j.neuroimage.2010.05.050. Epub 2010 May 24.

PMID:
20580846
33.

Low-level blast raises intracranial pressure and impairs cognitive function in rats: prophylaxis with processed cereal feed.

Säljö A, Bolouri H, Mayorga M, Svensson B, Hamberger A.

J Neurotrauma. 2010 Feb;27(2):383-9. doi: 10.1089/neu.2009.1053.

PMID:
19852583
34.

The gene regulatory network basis of the "community effect," and analysis of a sea urchin embryo example.

Bolouri H, Davidson EH.

Dev Biol. 2010 Apr 15;340(2):170-8. doi: 10.1016/j.ydbio.2009.06.007. Epub 2009 Jun 10. Review.

35.

Concussion in professional football: morphology of brain injuries in the NFL concussion model--part 16.

Hamberger A, Viano DC, Säljö A, Bolouri H.

Neurosurgery. 2009 Jun;64(6):1174-82; discussion 1182. doi: 10.1227/01.NEU.0000316855.40986.2A.

PMID:
19487898
36.

Concussion in professional football: animal model of brain injury--part 15.

Viano DC, Hamberger A, Bolouri H, Säljö A.

Neurosurgery. 2009 Jun;64(6):1162-73; discussion 1173. doi: 10.1227/01.NEU.0000345863.99099.C7.

PMID:
19487897
37.

Computational challenges of personal genomics.

Bolouri H.

Curr Genomics. 2008 Apr;9(2):80-7. doi: 10.2174/138920208784139564.

38.

Low-level blasts raise intracranial pressure and impair cognitive function in rats.

Säljö A, Svensson B, Mayorga M, Hamberger A, Bolouri H.

J Neurotrauma. 2009 Aug;26(8):1345-52. doi: 10.1089/neu.2008-0856.

PMID:
19317610
39.

Neuropathology and pressure in the pig brain resulting from low-impulse noise exposure.

Säljö A, Arrhén F, Bolouri H, Mayorga M, Hamberger A.

J Neurotrauma. 2008 Dec;25(12):1397-406. doi: 10.1089/neu.2008.0602.

PMID:
19146459
40.

A gene regulatory network armature for T lymphocyte specification.

Georgescu C, Longabaugh WJ, Scripture-Adams DD, David-Fung ES, Yui MA, Zarnegar MA, Bolouri H, Rothenberg EV.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20100-5. doi: 10.1073/pnas.0806501105. Epub 2008 Dec 22.

41.

Developmental gene regulatory networks in the zebrafish embryo.

Chan TM, Longabaugh W, Bolouri H, Chen HL, Tseng WF, Chao CH, Jang TH, Lin YI, Hung SC, Wang HD, Yuh CH.

Biochim Biophys Acta. 2009 Apr;1789(4):279-98. doi: 10.1016/j.bbagrm.2008.09.005. Epub 2008 Oct 8. Review.

PMID:
18992377
42.

Visualization, documentation, analysis, and communication of large-scale gene regulatory networks.

Longabaugh WJ, Davidson EH, Bolouri H.

Biochim Biophys Acta. 2009 Apr;1789(4):363-74. doi: 10.1016/j.bbagrm.2008.07.014. Epub 2008 Aug 6. Review.

43.

Embryonic pattern formation without morphogens.

Bolouri H.

Bioessays. 2008 May;30(5):412-7. doi: 10.1002/bies.20758. Review.

PMID:
18404688
44.

The Innate Immune Database (IIDB).

Korb M, Rust AG, Thorsson V, Battail C, Li B, Hwang D, Kennedy KA, Roach JC, Rosenberger CM, Gilchrist M, Zak D, Johnson C, Marzolf B, Aderem A, Shmulevich I, Bolouri H.

BMC Immunol. 2008 Mar 5;9:7. doi: 10.1186/1471-2172-9-7.

45.

Identification of complex shapes using a self organizing neural system.

Sabisch T, Ferguson A, Bolouri H.

IEEE Trans Neural Netw. 2000;11(4):921-34. doi: 10.1109/72.857772.

PMID:
18249819
46.
47.

The folic acid metabolite L-5-methyltetrahydrofolate effectively reduces total serum homocysteine level in orthotopic liver transplant recipients: a double-blind placebo-controlled study.

Akoglu B, Schrott M, Bolouri H, Jaffari A, Kutschera E, Caspary WF, Faust D.

Eur J Clin Nutr. 2008 Jun;62(6):796-801. Epub 2007 May 23.

PMID:
17522618
48.

Evolution of 'design' principles in biochemical networks.

de Atauri P, Orrell D, Ramsey S, Bolouri H.

Syst Biol (Stevenage). 2004 Jun;1(1):28-40.

PMID:
17052113
49.

Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast.

Ramsey SA, Smith JJ, Orrell D, Marelli M, Petersen TW, de Atauri P, Bolouri H, Aitchison JD.

Nat Genet. 2006 Sep;38(9):1082-7. Epub 2006 Aug 27.

PMID:
16936734
50.

Expression and functional profiling reveal distinct gene classes involved in fatty acid metabolism.

Smith JJ, Sydorskyy Y, Marelli M, Hwang D, Bolouri H, Rachubinski RA, Aitchison JD.

Mol Syst Biol. 2006;2:2006.0009. Epub 2006 Feb 21.

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