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Items: 1 to 50 of 63

1.

Gut microbiota modulate T cell trafficking into human colorectal cancer.

Cremonesi E, Governa V, Garzon JFG, Mele V, Amicarella F, Muraro MG, Trella E, Galati-Fournier V, Oertli D, Däster SR, Droeser RA, Weixler B, Bolli M, Rosso R, Nitsche U, Khanna N, Egli A, Keck S, Slotta-Huspenina J, Terracciano LM, Zajac P, Spagnoli GC, Eppenberger-Castori S, Janssen KP, Borsig L, Iezzi G.

Gut. 2018 Feb 6. pii: gutjnl-2016-313498. doi: 10.1136/gutjnl-2016-313498. [Epub ahead of print]

PMID:
29437871
2.

Cenerimod, a novel selective S1P1 receptor modulator with unique signaling properties.

Piali L, Birker-Robaczewska M, Lescop C, Froidevaux S, Schmitz N, Morrison K, Kohl C, Rey M, Studer R, Vezzali E, Hess P, Clozel M, Steiner B, Bolli MH, Nayler O.

Pharmacol Res Perspect. 2017 Dec;5(6). doi: 10.1002/prp2.370.

3.

S1P1 Modulator-Induced G αi Signaling and β-Arrestin Recruitment Are Both Necessary to Induce Rapid and Efficient Reduction of Blood Lymphocyte Count In Vivo.

Birker-Robaczewska M, Bolli M, Rey M, de Kanter R, Kohl C, Lescop C, Boucher M, Poirey S, Steiner B, Nayler O.

Mol Pharmacol. 2018 Feb;93(2):109-118. doi: 10.1124/mol.117.109140. Epub 2017 Dec 4.

PMID:
29203519
4.

The Discovery of Macitentan - A Standard Medicinal Chemistry Program?

Bolli MH.

Chimia (Aarau). 2017 Aug 9;71(7):420-429. doi: 10.2533/chimia.2016.420.

PMID:
28779766
5.

The Interplay Between Neutrophils and CD8+ T Cells Improves Survival in Human Colorectal Cancer.

Governa V, Trella E, Mele V, Tornillo L, Amicarella F, Cremonesi E, Muraro MG, Xu H, Droeser R, Däster SR, Bolli M, Rosso R, Oertli D, Eppenberger-Castori S, Terracciano LM, Iezzi G, Spagnoli GC.

Clin Cancer Res. 2017 Jul 15;23(14):3847-3858. doi: 10.1158/1078-0432.CCR-16-2047. Epub 2017 Jan 20.

6.

Metastatic Inflammatory Myofibroblastic Tumor of the Spleen: A Case Report and Review of the Literature.

Koechlin L, Zettl A, Koeberle D, von Flüe M, Bolli M.

Case Rep Surg. 2016;2016:8593242. doi: 10.1155/2016/8593242. Epub 2016 Nov 28.

7.

Discovery of Highly Potent Dual Orexin Receptor Antagonists via a Scaffold-Hopping Approach.

Heidmann B, Gatfield J, Roch C, Treiber A, Tortoioli S, Brotschi C, Williams JT, Bolli MH, Abele S, Sifferlen T, Jenck F, Boss C.

ChemMedChem. 2016 Oct 6;11(19):2132-2146. doi: 10.1002/cmdc.201600175. Epub 2016 Jul 8.

PMID:
27390287
8.

From bosentan (Tracleer®) to macitentan (Opsumit®): The medicinal chemistry perspective.

Boss C, Bolli MH, Gatfield J.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3381-94. doi: 10.1016/j.bmcl.2016.06.014. Epub 2016 Jun 10. Review.

PMID:
27321813
9.

Systematic immunohistochemical screening for Lynch syndrome in colorectal cancer: a single centre experience of 486 patients.

Zumstein V, Vinzens F, Zettl A, Heinimann K, Koeberle D, von Flüe M, Bolli M.

Swiss Med Wkly. 2016 May 6;146:w14315. doi: 10.4414/smw.2016.14315. eCollection 2016.

10.

Novel S1P1 receptor agonists - Part 4: Alkylaminomethyl substituted aryl head groups.

Lescop C, Müller C, Mathys B, Birker M, de Kanter R, Kohl C, Hess P, Nayler O, Rey M, Sieber P, Steiner B, Weller T, Bolli MH.

Eur J Med Chem. 2016 Jun 30;116:222-238. doi: 10.1016/j.ejmech.2016.03.048. Epub 2016 Mar 23.

PMID:
27061986
11.

Novel S1P1 receptor agonists - Part 5: From amino-to alkoxy-pyridines.

Bolli MH, Lescop C, Birker M, de Kanter R, Hess P, Kohl C, Nayler O, Rey M, Sieber P, Velker J, Weller T, Steiner B.

Eur J Med Chem. 2016 Jun 10;115:326-41. doi: 10.1016/j.ejmech.2016.03.020. Epub 2016 Mar 12.

PMID:
27027817
12.

Crohn's disease-associated large and small bowel adenocarcinoma with peritoneal carcinomatosis: two case reports.

Kobe A, Posabella A, Tampakis A, von Fluee M, Bolli M.

Int J Colorectal Dis. 2016 Aug;31(8):1491-2. doi: 10.1007/s00384-016-2539-0. Epub 2016 Mar 7. No abstract available.

PMID:
26951180
13.

Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer.

Amicarella F, Muraro MG, Hirt C, Cremonesi E, Padovan E, Mele V, Governa V, Han J, Huber X, Droeser RA, Zuber M, Adamina M, Bolli M, Rosso R, Lugli A, Zlobec I, Terracciano L, Tornillo L, Zajac P, Eppenberger-Castori S, Trapani F, Oertli D, Iezzi G.

Gut. 2017 Apr;66(4):692-704. doi: 10.1136/gutjnl-2015-310016. Epub 2015 Dec 30.

14.

The metabolism of the dual endothelin receptor antagonist macitentan in rat and dog.

Treiber A, Miraval T, Bolli MH, Funel JA, Segrestaa J, Seeland S.

Xenobiotica. 2016;46(3):253-67. doi: 10.3109/00498254.2015.1070302. Epub 2015 Sep 4.

PMID:
26337830
15.

Treatment of obesity and pulmonary arterial hypertension with inhibitors of the prostaglandin transporter: evaluation of patent WO2014/204895A1.

Dingemanse J, Bolli M, Iglarz M.

Expert Opin Ther Pat. 2015;25(9):1069-77. doi: 10.1517/13543776.2015.1056152. Epub 2015 Jun 24.

PMID:
26099857
16.

Distinct ETA receptor binding mode of macitentan as determined by site directed mutagenesis.

Gatfield J, Mueller Grandjean C, Bur D, Bolli MH, Nayler O.

PLoS One. 2014 Sep 16;9(9):e107809. doi: 10.1371/journal.pone.0107809. eCollection 2014.

17.

GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer.

Nebiker CA, Han J, Eppenberger-Castori S, Iezzi G, Hirt C, Amicarella F, Cremonesi E, Huber X, Padovan E, Angrisani B, Droeser RA, Rosso R, Bolli M, Oertli D, von Holzen U, Adamina M, Muraro MG, Mengus C, Zajac P, Sconocchia G, Zuber M, Tornillo L, Terracciano L, Spagnoli GC.

Clin Cancer Res. 2014 Jun 15;20(12):3094-106. doi: 10.1158/1078-0432.CCR-13-2774. Epub 2014 Apr 15.

18.

Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling.

Gatfield J, Monnier L, Studer R, Bolli MH, Steiner B, Nayler O.

Cell Signal. 2014 Jul;26(7):1576-88. doi: 10.1016/j.cellsig.2014.03.029. Epub 2014 Apr 2.

PMID:
24704119
19.

Novel S1P(1) receptor agonists--part 3: from thiophenes to pyridines.

Bolli MH, Abele S, Birker M, Bravo R, Bur D, de Kanter R, Kohl C, Grimont J, Hess P, Lescop C, Mathys B, Müller C, Nayler O, Rey M, Scherz M, Schmidt G, Seifert J, Steiner B, Velker J, Weller T.

J Med Chem. 2014 Jan 9;57(1):110-30. doi: 10.1021/jm4014696. Epub 2013 Dec 24.

PMID:
24367923
20.

Novel S1P(1) receptor agonists--part 2: from bicyclo[3.1.0]hexane-fused thiophenes to isobutyl substituted thiophenes.

Bolli MH, Velker J, Müller C, Mathys B, Birker M, Bravo R, Bur D, de Kanter R, Hess P, Kohl C, Lehmann D, Meyer S, Nayler O, Rey M, Scherz M, Steiner B.

J Med Chem. 2014 Jan 9;57(1):78-97. doi: 10.1021/jm401456d. Epub 2013 Dec 17.

PMID:
24345087
21.

Intraoperative neuromonitoring for surgical training in thyroid surgery: its routine use allows a safe operation instead of lack of experienced mentoring.

Alesina PF, Hinrichs J, Meier B, Cho EY, Bolli M, Walz MK.

World J Surg. 2014 Mar;38(3):592-8. doi: 10.1007/s00268-013-2372-3.

PMID:
24305928
22.

Novel S1P1 receptor agonists--part 1: From pyrazoles to thiophenes.

Bolli MH, Müller C, Mathys B, Abele S, Birker M, Bravo R, Bur D, Hess P, Kohl C, Lehmann D, Nayler O, Rey M, Meyer S, Scherz M, Schmidt G, Steiner B, Treiber A, Velker J, Weller T.

J Med Chem. 2013 Dec 12;56(23):9737-55. doi: 10.1021/jm4014373. Epub 2013 Nov 22.

PMID:
24266709
23.

Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signaling.

Sobel K, Menyhart K, Killer N, Renault B, Bauer Y, Studer R, Steiner B, Bolli MH, Nayler O, Gatfield J.

J Biol Chem. 2013 May 24;288(21):14839-51. doi: 10.1074/jbc.M112.426726. Epub 2013 Apr 15.

24.

A functional BCR in human IgA and IgM plasma cells.

Pinto D, Montani E, Bolli M, Garavaglia G, Sallusto F, Lanzavecchia A, Jarrossay D.

Blood. 2013 May 16;121(20):4110-4. doi: 10.1182/blood-2012-09-459289. Epub 2013 Apr 2.

25.

The discovery of N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide (Macitentan), an orally active, potent dual endothelin receptor antagonist.

Bolli MH, Boss C, Binkert C, Buchmann S, Bur D, Hess P, Iglarz M, Meyer S, Rein J, Rey M, Treiber A, Clozel M, Fischli W, Weller T.

J Med Chem. 2012 Sep 13;55(17):7849-61. doi: 10.1021/jm3009103. Epub 2012 Aug 16.

PMID:
22862294
26.

Ectopic substernal thyroid tissue: a challenging differential diagnosis.

Bongiovanni M, Suriano S, Bolli M, Cattaneo F, Fasolini F, Giovanella L.

J Clin Endocrinol Metab. 2012 Mar;97(3):719-20. doi: 10.1210/jc.2011-2543. Epub 2012 Jan 18. No abstract available.

PMID:
22259054
27.

Images in endocrine pathology: a starry-sky in the thyroid.

Bongiovanni M, Mazzucchelli L, Martin V, Crippa S, Bolli M, Suriano S, Giovanella L.

Endocr Pathol. 2012 Mar;23(1):79-81. doi: 10.1007/s12022-011-9191-6. No abstract available.

PMID:
22212458
28.

The selective sphingosine 1-phosphate receptor 1 agonist ponesimod protects against lymphocyte-mediated tissue inflammation.

Piali L, Froidevaux S, Hess P, Nayler O, Bolli MH, Schlosser E, Kohl C, Steiner B, Clozel M.

J Pharmacol Exp Ther. 2011 May;337(2):547-56. doi: 10.1124/jpet.110.176487. Epub 2011 Feb 23.

29.

Synthetic sphingosine 1-phosphate receptor modulators--opportunities and potential pitfalls.

Bolli MH, Lescop C, Nayler O.

Curr Top Med Chem. 2011;11(6):726-57. Review.

PMID:
21261590
30.

2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.

Bolli MH, Abele S, Binkert C, Bravo R, Buchmann S, Bur D, Gatfield J, Hess P, Kohl C, Mangold C, Mathys B, Menyhart K, Müller C, Nayler O, Scherz M, Schmidt G, Sippel V, Steiner B, Strasser D, Treiber A, Weller T.

J Med Chem. 2010 May 27;53(10):4198-211. doi: 10.1021/jm100181s.

PMID:
20446681
31.

Intranodal immunization with a vaccinia virus encoding multiple antigenic epitopes and costimulatory molecules in metastatic melanoma.

Adamina M, Rosenthal R, Weber WP, Frey DM, Viehl CT, Bolli M, Huegli RW, Jacob AL, Heberer M, Oertli D, Marti W, Spagnoli GC, Zajac P.

Mol Ther. 2010 Mar;18(3):651-9. doi: 10.1038/mt.2009.275. Epub 2009 Nov 24.

32.

Surgical glove perforation and the risk of surgical site infection.

Misteli H, Weber WP, Reck S, Rosenthal R, Zwahlen M, Fueglistaler P, Bolli MK, Oertli D, Widmer AF, Marti WR.

Arch Surg. 2009 Jun;144(6):553-8; discussion 558. doi: 10.1001/archsurg.2009.60.

PMID:
19528389
33.

Differential responsiveness to IL-2, IL-7, and IL-15 common receptor gamma chain cytokines by antigen-specific peripheral blood naive or memory cytotoxic CD8+ T cells from healthy donors and melanoma patients.

Rosenthal R, Groeper C, Bracci L, Adamina M, Feder-Mengus C, Zajac P, Iezzi G, Bolli M, Weber WP, Frey DM, von Holzen U, Oertli D, Heberer M, Spagnoli GC.

J Immunother. 2009 Apr;32(3):252-61. doi: 10.1097/CJI.0b013e3181998e03.

PMID:
19242375
34.

Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist.

Iglarz M, Binkert C, Morrison K, Fischli W, Gatfield J, Treiber A, Weller T, Bolli MH, Boss C, Buchmann S, Capeleto B, Hess P, Qiu C, Clozel M.

J Pharmacol Exp Ther. 2008 Dec;327(3):736-45. doi: 10.1124/jpet.108.142976. Epub 2008 Sep 9.

35.

Surgery of liver metastasis in gynecological cancer - indication and results.

Kollmar O, Moussavian MR, Richter S, Bolli M, Schilling MK.

Onkologie. 2008 Jul;31(7):375-9. doi: 10.1159/000135516. Epub 2008 Jun 23.

PMID:
18596384
36.

The timing of surgical antimicrobial prophylaxis.

Weber WP, Marti WR, Zwahlen M, Misteli H, Rosenthal R, Reck S, Fueglistaler P, Bolli M, Trampuz A, Oertli D, Widmer AF.

Ann Surg. 2008 Jun;247(6):918-26. doi: 10.1097/SLA.0b013e31816c3fec.

PMID:
18520217
37.

Backbone-base inclination as a fundamental determinant of nucleic acid self- and cross-pairing.

Pallan PS, Lubini P, Bolli M, Egli M.

Nucleic Acids Res. 2007;35(19):6611-24. Epub 2007 Sep 28.

38.

Pancreatojejunal leakage after pancreas head resection: anatomic and surgeon-related factors.

Kollmar O, Moussavian MR, Bolli M, Richter S, Schilling MK.

J Gastrointest Surg. 2007 Dec;11(12):1699-703. Epub 2007 Sep 2.

PMID:
17786530
39.

[Organization and working conditions].

Bolli M, Caffari B, Caporali MG, De Mei B, Donati S, Fantozzi L, Galluzzo L, Ranghiasci A, Solimini R, Vanacore N, Vichi M; Gruppo Valorizzazione Risorse Umane.

Epidemiol Prev. 2007 Jan-Feb;31(1):9-10. Italian. No abstract available.

40.

[Ileus disease].

Plusczyk T, Bolli M, Schilling M.

Chirurg. 2006 Oct;77(10):898-903. German.

PMID:
16969660
41.

[Incision and closure of the abdominal wall].

Bolli M, Schilling M.

Chirurg. 2006 May;77(5):408-13. German.

PMID:
16703395
42.

Active antigen-specific immunotherapy of melanoma: from basic science to clinical investigation.

Spagnoli GC, Adamina M, Bolli M, Weber WP, Zajac P, Marti W, Oertli D, Heberer M, Harder F.

World J Surg. 2005 Jun;29(6):692-9. Review.

PMID:
15883665
43.

NY-ESO-1/LAGE-1 coexpression with MAGE-A cancer/testis antigens: a tissue microarray study.

Bolli M, Schultz-Thater E, Zajac P, Guller U, Feder C, Sanguedolce F, Carafa V, Terracciano L, Hudolin T, Spagnoli GC, Tornillo L.

Int J Cancer. 2005 Jul 20;115(6):960-6.

44.

Selective responsiveness to common gamma chain cytokines in peripheral blood-derived cytotoxic T lymphocytes induced by Melan-A/MART-1(27-35)targeted active specific immunotherapy.

von Holzen U, Adamina M, Bolli M, Weber WP, Zajac P, Groeper C, Reschner A, Feder C, Schumacher R, Marti W, Oertli D, Heberer M, Spagnoli GC.

Int J Cancer. 2005 Jun 10;115(2):248-55.

45.

The incidence of iliac aneurysms in patients with abdominal aortic aneurysms: comparison of four centers in Europe and the USA.

Eugster T, Bolli M, Pfeiffer T, Sandmann W, Chuter TA, Messina LM, Mühlthaler H, Lottersberger C, Fraedrich G, Gürke L, Stierli P.

Vasa. 2004 May;33(2):68-71.

PMID:
15224457
46.

Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists.

Bolli MH, Marfurt J, Grisostomi C, Boss C, Binkert C, Hess P, Treiber A, Thorin E, Morrison K, Buchmann S, Bur D, Ramuz H, Clozel M, Fischli W, Weller T.

J Med Chem. 2004 May 20;47(11):2776-95.

PMID:
15139756
47.

Influenza virosomes enhance class I restricted CTL induction through CD4+ T cell activation.

Schumacher R, Adamina M, Zurbriggen R, Bolli M, Padovan E, Zajac P, Heberer M, Spagnoli GC.

Vaccine. 2004 Jan 26;22(5-6):714-23.

PMID:
14741164
48.

Encapsulation into sterically stabilised liposomes enhances the immunogenicity of melanoma-associated Melan-A/MART-1 epitopes.

Adamina M, Bolli M, Albo F, Cavazza A, Zajac P, Padovan E, Schumacher R, Reschner A, Feder C, Marti WR, Oertli D, Heberer M, Spagnoli GC.

Br J Cancer. 2004 Jan 12;90(1):263-9.

49.

Phase I/II clinical trial of a nonreplicative vaccinia virus expressing multiple HLA-A0201-restricted tumor-associated epitopes and costimulatory molecules in metastatic melanoma patients.

Zajac P, Oertli D, Marti W, Adamina M, Bolli M, Guller U, Noppen C, Padovan E, Schultz-Thater E, Heberer M, Spagnoli G.

Hum Gene Ther. 2003 Nov 1;14(16):1497-510.

PMID:
14577912
50.

[Swiss surgery: quo vadis? Reader and market analysis for strategic positioning of a specialty journal].

Freiermuth O, Todorov A, Bolli M, Heberer M.

Swiss Surg. 2003;9(2):43-53. German.

PMID:
12723283

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