Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 236

1.

Efficacy of Internet-Based Cognitive Behavioral Therapy for Treatment-Induced Menopausal Symptoms in Breast Cancer Survivors: Results of a Randomized Controlled Trial.

Atema V, van Leeuwen M, Kieffer JM, Oldenburg HSA, van Beurden M, Gerritsma MA, Kuenen MA, Plaisier PW, Lopes Cardozo AMF, van Riet YEA, Heuff G, Rijna H, van der Meij S, Noorda EM, Timmers GJ, Vrouenraets BC, Bollen M, van der Veen H, Bijker N, Hunter MS, Aaronson NK.

J Clin Oncol. 2019 Apr 1;37(10):809-822. doi: 10.1200/JCO.18.00655. Epub 2019 Feb 14.

PMID:
30763176
2.

Coordination of Timers and Sensors in Cell Signaling.

Qian J, Gelens L, Bollen M.

Bioessays. 2019 Mar;41(3):e1800217. doi: 10.1002/bies.201800217. Epub 2019 Feb 7.

PMID:
30730051
3.

Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1.

Heroes E, Van der Hoeven G, Choy MS, Garcia JDP, Ferreira M, Nys M, Derua R, Beullens M, Ulens C, Peti W, Van Meervelt L, Page R, Bollen M.

Structure. 2019 Mar 5;27(3):507-518.e5. doi: 10.1016/j.str.2018.12.002. Epub 2019 Jan 17.

PMID:
30661852
4.

Correction: MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.

Beke L, Kig C, Linders JTM, Boens S, Boeckx A, van Heerde E, Parade M, De Bondt A, Van den Wyngaert I, Bashir T, Ogata S, Meerpoel L, Van Eynde A, Johnson CN, Beullens M, Brehmer D, Bollen M.

Biosci Rep. 2018 Nov 30;38(6). pii: BSR-20150194_COR. doi: 10.1042/BSR-20150194_COR. Print 2018 Dec 21. No abstract available.

5.

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

Weith M, Seiler J, van den Boom J, Kracht M, Hülsmann J, Primorac I, Del Pino Garcia J, Kaschani F, Kaiser M, Musacchio A, Bollen M, Meyer H.

Mol Cell. 2018 Nov 15;72(4):766-777.e6. doi: 10.1016/j.molcel.2018.09.020. Epub 2018 Oct 18.

PMID:
30344098
6.

The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2.

Ferreira M, Verbinnen I, Fardilha M, Van Eynde A, Bollen M.

J Biol Chem. 2018 Nov 23;293(47):18031-18039. doi: 10.1074/jbc.AC118.005577. Epub 2018 Oct 10.

PMID:
30305391
7.

A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions.

Wu D, De Wever V, Derua R, Winkler C, Beullens M, Van Eynde A, Bollen M.

J Biol Chem. 2018 Sep 28;293(39):15152-15162. doi: 10.1074/jbc.RA118.004132. Epub 2018 Aug 16.

PMID:
30115685
8.

KNL1 Binding to PP1 and Microtubules Is Mutually Exclusive.

Bajaj R, Bollen M, Peti W, Page R.

Structure. 2018 Oct 2;26(10):1327-1336.e4. doi: 10.1016/j.str.2018.06.013. Epub 2018 Aug 9.

PMID:
30100357
9.

Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics.

Ferreira M, Beullens M, Bollen M, Van Eynde A.

Biochim Biophys Acta Mol Cell Res. 2019 Jan;1866(1):16-30. doi: 10.1016/j.bbamcr.2018.07.019. Epub 2018 Jul 26.

PMID:
30056088
10.

Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks.

Winkler C, Rouget R, Wu D, Beullens M, Van Eynde A, Bollen M.

J Cell Sci. 2018 Jul 9;131(13). pii: jcs214932. doi: 10.1242/jcs.214932.

11.

A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α.

Crespillo-Casado A, Claes Z, Choy MS, Peti W, Bollen M, Ron D.

J Biol Chem. 2018 May 18;293(20):7766-7776. doi: 10.1074/jbc.RA118.002325. Epub 2018 Apr 4.

12.

Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome.

Smith-Moore S, Neil SJD, Fraefel C, Linden RM, Bollen M, Rowe HM, Henckaerts E.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3529-E3538. doi: 10.1073/pnas.1721883115. Epub 2018 Mar 26.

13.

Correction: Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2.

Cimpean A, Stefan C, Gijsbers R, Stalmans W, Bollen M.

Biochem J. 2017 Dec 14;474(24):4273-4274. doi: 10.1042/BCJ-2004-0465_COR. No abstract available.

PMID:
29242384
14.

An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint.

Qian J, García-Gimeno MA, Beullens M, Manzione MG, Van der Hoeven G, Igual JC, Heredia M, Sanz P, Gelens L, Bollen M.

Mol Cell. 2017 Nov 16;68(4):715-730.e5. doi: 10.1016/j.molcel.2017.10.011. Epub 2017 Nov 9.

15.

The Importance of Kinase-Phosphatase Integration: Lessons from Mitosis.

Gelens L, Qian J, Bollen M, Saurin AT.

Trends Cell Biol. 2018 Jan;28(1):6-21. doi: 10.1016/j.tcb.2017.09.005. Epub 2017 Oct 28. Review.

PMID:
29089159
16.

The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis.

Ferreira M, Boens S, Winkler C, Szekér K, Verbinnen I, Van Eynde A, Fardilha M, Bollen M.

Sci Rep. 2017 Oct 17;7(1):13364. doi: 10.1038/s41598-017-13809-y.

17.

ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis.

Chourabi M, Liew MS, Lim S, H'mida-Ben Brahim D, Boussofara L, Dai L, Wong PM, Foo JN, Sriha B, Robinson KS, Denil S, Common JE, Mamaï O, Ben Khalifa Y, Bollen M, Liu J, Denguezli M, Bonnard C, Saad A, Reversade B.

J Invest Dermatol. 2018 Feb;138(2):291-300. doi: 10.1016/j.jid.2017.08.045. Epub 2017 Sep 28.

18.

Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells.

Kig C, Beullens M, Beke L, Van Eynde A, Linders JT, Brehmer D, Bollen M.

J Biol Chem. 2017 Aug 4;292(31):12786. doi: 10.1074/jbc.A113.471433. No abstract available.

19.

Correction: Biogenesis and activity regulation of protein phosphatase 1.

Verbinnen I, Ferreira M, Bollen M.

Biochem Soc Trans. 2017 Apr 15;45(2):583-584. doi: 10.1042/BST-2016-0154C_COR. No abstract available.

PMID:
28408498
20.

Biogenesis and activity regulation of protein phosphatase 1.

Verbinnen I, Ferreira M, Bollen M.

Biochem Soc Trans. 2017 Feb 8;45(1):89-99. doi: 10.1042/BST20160154. Review. Erratum in: Biochem Soc Trans. 2017 Apr 15;45(2):583-584.

PMID:
28202662
21.

Split-BioID: a proximity biotinylation assay for dimerization-dependent protein interactions.

De Munter S, Görnemann J, Derua R, Lesage B, Qian J, Heroes E, Waelkens E, Van Eynde A, Beullens M, Bollen M.

FEBS Lett. 2017 Jan;591(2):415-424. doi: 10.1002/1873-3468.12548. Epub 2017 Jan 12.

22.

Expanding the PP2A Interactome by Defining a B56-Specific SLiM.

Wang X, Bajaj R, Bollen M, Peti W, Page R.

Structure. 2016 Dec 6;24(12):2174-2181. doi: 10.1016/j.str.2016.09.010. Epub 2016 Oct 27.

23.

Major allergen content consistency of SQ house dust mite sublingual immunotherapy tablets and relevance across geographic regions.

Nolte H, Plunkett G, Grosch K, Larsen JN, Lund K, Bollen M.

Ann Allergy Asthma Immunol. 2016 Sep;117(3):298-303. doi: 10.1016/j.anai.2016.07.004.

PMID:
27613464
24.

The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism.

Kumar GS, Gokhan E, De Munter S, Bollen M, Vagnarelli P, Peti W, Page R.

Elife. 2016 Aug 30;5. pii: e16539. doi: 10.7554/eLife.16539.

25.

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool.

Sannerud R, Esselens C, Ejsmont P, Mattera R, Rochin L, Tharkeshwar AK, De Baets G, De Wever V, Habets R, Baert V, Vermeire W, Michiels C, Groot AJ, Wouters R, Dillen K, Vints K, Baatsen P, Munck S, Derua R, Waelkens E, Basi GS, Mercken M, Vooijs M, Bollen M, Schymkowitz J, Rousseau F, Bonifacino JS, Van Niel G, De Strooper B, Annaert W.

Cell. 2016 Jun 30;166(1):193-208. doi: 10.1016/j.cell.2016.05.020. Epub 2016 Jun 9.

26.

The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression.

Rambout X, Detiffe C, Bruyr J, Mariavelle E, Cherkaoui M, Brohée S, Demoitié P, Lebrun M, Soin R, Lesage B, Guedri K, Beullens M, Bollen M, Farazi TA, Kettmann R, Struman I, Hill DE, Vidal M, Kruys V, Simonis N, Twizere JC, Dequiedt F.

Nat Struct Mol Biol. 2016 Jul;23(7):663-72. doi: 10.1038/nsmb.3243. Epub 2016 Jun 6.

27.

Brief Report: The Deletion of the Phosphatase Regulator NIPP1 Causes Progenitor Cell Expansion in the Adult Liver.

Boens S, Verbinnen I, Verhulst S, Szekér K, Ferreira M, Gevaert T, Baes M, Roskams T, van Grunsven LA, Van Eynde A, Bollen M.

Stem Cells. 2016 Aug;34(8):2256-62. doi: 10.1002/stem.2375. Epub 2016 Jun 20.

28.

Post-translational Control of the Temporal Dynamics of Transcription Factor Activity Regulates Neurogenesis.

Quan XJ, Yuan L, Tiberi L, Claeys A, De Geest N, Yan J, van der Kant R, Xie WR, Klisch TJ, Shymkowitz J, Rousseau F, Bollen M, Beullens M, Zoghbi HY, Vanderhaeghen P, Hassan BA.

Cell. 2016 Jan 28;164(3):460-75. doi: 10.1016/j.cell.2015.12.048.

29.

Cdk1 orders mitotic events through coordination of a chromosome-associated phosphatase switch.

Qian J, Beullens M, Huang J, De Munter S, Lesage B, Bollen M.

Nat Commun. 2015 Dec 17;6:10215. doi: 10.1038/ncomms10215.

30.

The selective inhibition of protein phosphatase-1 results in mitotic catastrophe and impaired tumor growth.

Winkler C, De Munter S, Van Dessel N, Lesage B, Heroes E, Boens S, Beullens M, Van Eynde A, Bollen M.

J Cell Sci. 2015 Dec 15;128(24):4526-37. doi: 10.1242/jcs.175588. Epub 2015 Nov 5.

31.

MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.

Beke L, Kig C, Linders JT, Boens S, Boeckx A, van Heerde E, Parade M, De Bondt A, Van den Wyngaert I, Bashir T, Ogata S, Meerpoel L, Van Eynde A, Johnson CN, Beullens M, Brehmer D, Bollen M.

Biosci Rep. 2015 Oct 2;35(6). pii: e00267. doi: 10.1042/BSR20150194. Erratum in: Biosci Rep. 2018 Nov 30;38(6):.

32.

DNA Methylation-Guided Prediction of Clinical Failure in High-Risk Prostate Cancer.

Litovkin K, Van Eynde A, Joniau S, Lerut E, Laenen A, Gevaert T, Gevaert O, Spahn M, Kneitz B, Gramme P, Helleputte T, Isebaert S, Haustermans K, Bollen M.

PLoS One. 2015 Jun 18;10(6):e0130651. doi: 10.1371/journal.pone.0130651. eCollection 2015.

33.

Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits.

Verheyen T, Görnemann J, Verbinnen I, Boens S, Beullens M, Van Eynde A, Bollen M.

Nucleic Acids Res. 2015 Jul 13;43(12):5771-84. doi: 10.1093/nar/gkv500. Epub 2015 May 18.

34.

Protein phosphatase PP1-NIPP1 activates mesenchymal genes in HeLa cells.

Van Dessel N, Boens S, Lesage B, Winkler C, Görnemann J, Van Eynde A, Bollen M.

FEBS Lett. 2015 May 22;589(12):1314-21. doi: 10.1016/j.febslet.2015.04.017. Epub 2015 Apr 20.

35.

Metals in the active site of native protein phosphatase-1.

Heroes E, Rip J, Beullens M, Van Meervelt L, De Gendt S, Bollen M.

J Inorg Biochem. 2015 Aug;149:1-5. doi: 10.1016/j.jinorgbio.2015.03.012. Epub 2015 Mar 31.

PMID:
25890482
36.

Cell cycle: It takes three to find the exit.

Bollen M.

Nature. 2015 Jan 1;517(7532):29-30. doi: 10.1038/nature14080. Epub 2014 Dec 10. No abstract available.

PMID:
25487157
37.

Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.

Eiteneuer A, Seiler J, Weith M, Beullens M, Lesage B, Krenn V, Musacchio A, Bollen M, Meyer H.

EMBO J. 2014 Nov 18;33(22):2704-20. doi: 10.15252/embj.201489054. Epub 2014 Oct 8.

38.

Methylation of PITX2, HOXD3, RASSF1 and TDRD1 predicts biochemical recurrence in high-risk prostate cancer.

Litovkin K, Joniau S, Lerut E, Laenen A, Gevaert O, Spahn M, Kneitz B, Isebaert S, Haustermans K, Beullens M, Van Eynde A, Bollen M.

J Cancer Res Clin Oncol. 2014 Nov;140(11):1849-61. doi: 10.1007/s00432-014-1738-8. Epub 2014 Jun 18.

PMID:
24938434
39.

Kinetochore signalling: the KIss that MELTs Knl1.

Bollen M.

Curr Biol. 2014 Jan 20;24(2):R68-70. doi: 10.1016/j.cub.2013.11.053.

40.

Chemical activators of protein phosphatase-1 induce calcium release inside intact cells.

Reither G, Chatterjee J, Beullens M, Bollen M, Schultz C, Köhn M.

Chem Biol. 2013 Sep 19;20(9):1179-86. doi: 10.1016/j.chembiol.2013.07.008. Epub 2013 Aug 22.

41.

Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle.

Lobbestael E, Zhao J, Rudenko IN, Beylina A, Gao F, Wetter J, Beullens M, Bollen M, Cookson MR, Baekelandt V, Nichols RJ, Taymans JM.

Biochem J. 2013 Nov 15;456(1):119-28. doi: 10.1042/BJ20121772.

42.

Interactor-guided dephosphorylation by protein phosphatase-1.

Boens S, Szekér K, Van Eynde A, Bollen M.

Methods Mol Biol. 2013;1053:271-81. doi: 10.1007/978-1-62703-562-0_16. Review.

PMID:
23860659
43.

4D-networking by mitotic phosphatases.

Qian J, Winkler C, Bollen M.

Curr Opin Cell Biol. 2013 Dec;25(6):697-703. doi: 10.1016/j.ceb.2013.06.005. Epub 2013 Jul 9. Review.

PMID:
23849679
44.

Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells.

Kig C, Beullens M, Beke L, Van Eynde A, Linders JT, Brehmer D, Bollen M.

J Biol Chem. 2013 Aug 16;288(33):24200-12. doi: 10.1074/jbc.M113.471433. Epub 2013 Jul 8. Retraction in: J Biol Chem. 2017 Aug 4;292(31):12786.

45.

Aurora B defines its own chromosomal targeting by opposing the recruitment of the phosphatase scaffold Repo-Man.

Qian J, Beullens M, Lesage B, Bollen M.

Curr Biol. 2013 Jun 17;23(12):1136-43. doi: 10.1016/j.cub.2013.05.017. Epub 2013 Jun 6.

46.

NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes.

Minnebo N, Görnemann J, O'Connell N, Van Dessel N, Derua R, Vermunt MW, Page R, Beullens M, Peti W, Van Eynde A, Bollen M.

Nucleic Acids Res. 2013 Jan;41(2):842-54. doi: 10.1093/nar/gks1255. Epub 2012 Dec 13.

47.

Challenges and opportunities in the development of protein phosphatase-directed therapeutics.

De Munter S, Köhn M, Bollen M.

ACS Chem Biol. 2013 Jan 18;8(1):36-45. doi: 10.1021/cb300597g. Epub 2012 Dec 20. Review.

PMID:
23214403
48.

CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90.

Breuer D, Kotelkin A, Ammosova T, Kumari N, Ivanov A, Ilatovskiy AV, Beullens M, Roane PR, Bollen M, Petukhov MG, Kashanchi F, Nekhai S.

Retrovirology. 2012 Nov 9;9:94. doi: 10.1186/1742-4690-9-94.

49.

Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway.

Garcia-Haro L, Garcia-Gimeno MA, Neumann D, Beullens M, Bollen M, Sanz P.

FEBS Lett. 2012 Nov 30;586(23):4241-7. doi: 10.1016/j.febslet.2012.10.032. Epub 2012 Oct 29.

50.

Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification.

Jansen S, Perrakis A, Ulens C, Winkler C, Andries M, Joosten RP, Van Acker M, Luyten FP, Moolenaar WH, Bollen M.

Structure. 2012 Nov 7;20(11):1948-59. doi: 10.1016/j.str.2012.09.001. Epub 2012 Oct 4.

Supplemental Content

Loading ...
Support Center