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Items: 23


The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes.

Hill DL, Pierson W, Bolland DJ, Mkindi C, Carr EJ, Wang J, Houard S, Wingett SW, Audran R, Wallin EF, Jongo SA, Kamaka K, Zand M, Spertini F, Daubenberger C, Corcoran AE, Linterman MA.

J Exp Med. 2019 Jun 7. pii: jem.20190301. doi: 10.1084/jem.20190301. [Epub ahead of print]


Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells.

Koohy H, Bolland DJ, Matheson LS, Schoenfelder S, Stellato C, Dimond A, Várnai C, Chovanec P, Chessa T, Denizot J, Manzano Garcia R, Wingett SW, Freire-Pritchett P, Nagano T, Hawkins P, Stephens L, Elderkin S, Spivakov M, Fraser P, Corcoran AE, Varga-Weisz PD.

Genome Biol. 2018 Sep 5;19(1):126. doi: 10.1186/s13059-018-1489-y.


Unbiased quantification of immunoglobulin diversity at the DNA level with VDJ-seq.

Chovanec P, Bolland DJ, Matheson LS, Wood AL, Krueger F, Andrews S, Corcoran AE.

Nat Protoc. 2018 Jun;13(6):1232-1252. doi: 10.1038/nprot.2018.021. Epub 2018 May 3.


Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination.

Matheson LS, Bolland DJ, Chovanec P, Krueger F, Andrews S, Koohy H, Corcoran AE.

Front Immunol. 2017 Nov 17;8:1550. doi: 10.3389/fimmu.2017.01550. eCollection 2017.


Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination.

Bolland DJ, Koohy H, Wood AL, Matheson LS, Krueger F, Stubbington MJ, Baizan-Edge A, Chovanec P, Stubbs BA, Tabbada K, Andrews SR, Spivakov M, Corcoran AE.

Cell Rep. 2016 Jun 14;15(11):2475-87. doi: 10.1016/j.celrep.2016.05.020. Epub 2016 Jun 2.


Robust 3D DNA FISH using directly labeled probes.

Bolland DJ, King MR, Reik W, Corcoran AE, Krueger C.

J Vis Exp. 2013 Aug 15;(78). doi: 10.3791/50587.


ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma.

Loizou JI, Sancho R, Kanu N, Bolland DJ, Yang F, Rada C, Corcoran AE, Behrens A.

Cancer Cell. 2011 May 17;19(5):587-600. doi: 10.1016/j.ccr.2011.03.022.


RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation.

Collins A, Hewitt SL, Chaumeil J, Sellars M, Micsinai M, Allinne J, Parisi F, Nora EP, Bolland DJ, Corcoran AE, Kluger Y, Bosselut R, Ellmeier W, Chong MM, Littman DR, Skok JA.

Immunity. 2011 Mar 25;34(3):303-14. doi: 10.1016/j.immuni.2011.03.004.


The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.

Ramadani F, Bolland DJ, Garcon F, Emery JL, Vanhaesebroeck B, Corcoran AE, Okkenhaug K.

Sci Signal. 2010 Aug 10;3(134):ra60. doi: 10.1126/scisignal.2001104.


Large-scale chromatin remodeling at the immunoglobulin heavy chain locus: a paradigm for multigene regulation.

Bolland DJ, Wood AL, Corcoran AE.

Adv Exp Med Biol. 2009;650:59-72. Review.


AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.

Robbiani DF, Bothmer A, Callen E, Reina-San-Martin B, Dorsett Y, Difilippantonio S, Bolland DJ, Chen HT, Corcoran AE, Nussenzweig A, Nussenzweig MC.

Cell. 2008 Dec 12;135(6):1028-38. doi: 10.1016/j.cell.2008.09.062.


Heavy chain-only antibodies are spontaneously produced in light chain-deficient mice.

Zou X, Osborn MJ, Bolland DJ, Smith JA, Corcos D, Hamon M, Oxley D, Hutchings A, Morgan G, Santos F, Kilshaw PJ, Taussig MJ, Corcoran AE, Brüggemann M.

J Exp Med. 2007 Dec 24;204(13):3271-83. Epub 2007 Dec 17.


Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.

Clapp J, Mitchell LM, Bolland DJ, Fantes J, Corcoran AE, Scotting PJ, Armour JA, Hewitt JE.

Am J Hum Genet. 2007 Aug;81(2):264-79. Epub 2007 Jun 27.


Myc dynamically and preferentially relocates to a transcription factory occupied by Igh.

Osborne CS, Chakalova L, Mitchell JA, Horton A, Wood AL, Bolland DJ, Corcoran AE, Fraser P.

PLoS Biol. 2007 Aug;5(8):e192.


Antisense intergenic transcription precedes Igh D-to-J recombination and is controlled by the intronic enhancer Emu.

Bolland DJ, Wood AL, Afshar R, Featherstone K, Oltz EM, Corcoran AE.

Mol Cell Biol. 2007 Aug;27(15):5523-33. Epub 2007 May 25.


Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region.

Johnston CM, Wood AL, Bolland DJ, Corcoran AE.

J Immunol. 2006 Apr 1;176(7):4221-34.


Regulation of IgH gene assembly: role of the intronic enhancer and 5'DQ52 region in targeting DHJH recombination.

Afshar R, Pierce S, Bolland DJ, Corcoran A, Oltz EM.

J Immunol. 2006 Feb 15;176(4):2439-47.


Genomic analysis of facioscapulohumeral muscular dystrophy.

Clapp J, Bolland DJ, Hewitt JE.

Brief Funct Genomic Proteomic. 2003 Oct;2(3):213-23. Review.


Antisense intergenic transcription in V(D)J recombination.

Bolland DJ, Wood AL, Johnston CM, Bunting SF, Morgan G, Chakalova L, Fraser PJ, Corcoran AE.

Nat Immunol. 2004 Jun;5(6):630-7. Epub 2004 Apr 25.


Identification of the autoantigen SART-1 as a candidate gene for the development of atopy.

Wheatley AP, Bolland DJ, Hewitt JE, Dewar JC, Hall IP.

Hum Mol Genet. 2002 Sep 1;11(18):2143-6.


Genomic analysis of human chromosome 10q and 4q telomeres suggests a common origin.

van Geel M, Dickson MC, Beck AF, Bolland DJ, Frants RR, van der Maarel SM, de Jong PJ, Hewitt JE.

Genomics. 2002 Feb;79(2):210-7.


Intron loss in the SART1 genes of Fugu rubripes and Tetraodon nigroviridis.

Bolland DJ, Hewitt JE.

Gene. 2001 Jun 13;271(1):43-9.


High-resolution mapping of mouse chromosome 8 identifies an evolutionary chromosomal breakpoint.

Grewal PK, Bolland DJ, Todd LC, Hewitt JE.

Mamm Genome. 1998 Aug;9(8):603-7.


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