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Items: 1 to 50 of 181

1.

De novo production of aromatic m-cresol in Saccharomyces cerevisiae mediated by heterologous polyketide synthases combined with a 6-methylsalicylic acid decarboxylase.

Hitschler J, Boles E.

Metab Eng Commun. 2019 May 4;9:e00093. doi: 10.1016/j.mec.2019.e00093. eCollection 2019 Dec.

PMID:
31193192
2.

Bacterial bifunctional chorismate mutase-prephenate dehydratase PheA increases flux into the yeast phenylalanine pathway and improves mandelic acid production.

Reifenrath M, Bauer M, Oreb M, Boles E.

Metab Eng Commun. 2018 Sep 22;7:e00079. doi: 10.1016/j.mec.2018.e00079. eCollection 2018 Dec.

3.

A Yeast-Based Biosensor for Screening of Short- and Medium-Chain Fatty Acid Production.

Baumann L, Rajkumar AS, Morrissey JP, Boles E, Oreb M.

ACS Synth Biol. 2018 Nov 16;7(11):2640-2646. doi: 10.1021/acssynbio.8b00309. Epub 2018 Oct 19.

PMID:
30338986
4.

A superfolder variant of pH-sensitive pHluorin for in vivo pH measurements in the endoplasmic reticulum.

Reifenrath M, Boles E.

Sci Rep. 2018 Aug 10;8(1):11985. doi: 10.1038/s41598-018-30367-z.

5.

An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol in Saccharomyces cerevisiae.

Henritzi S, Fischer M, Grininger M, Oreb M, Boles E.

Biotechnol Biofuels. 2018 Jun 1;11:150. doi: 10.1186/s13068-018-1149-1. eCollection 2018.

6.

An expanded enzyme toolbox for production of cis, cis-muconic acid and other shikimate pathway derivatives in Saccharomyces cerevisiae.

Brückner C, Oreb M, Kunze G, Boles E, Tripp J.

FEMS Yeast Res. 2018 Mar 1;18(2). doi: 10.1093/femsyr/foy017.

PMID:
29462295
7.
8.

A Growth-Based Screening System for Hexose Transporters in Yeast.

Boles E, Oreb M.

Methods Mol Biol. 2018;1713:123-135. doi: 10.1007/978-1-4939-7507-5_10.

PMID:
29218522
9.

Optimisation of trans-cinnamic acid and hydrocinnamyl alcohol production with recombinant Saccharomyces cerevisiae and identification of cinnamyl methyl ketone as a by-product.

Gottardi M, Grün P, Bode HB, Hoffmann T, Schwab W, Oreb M, Boles E.

FEMS Yeast Res. 2017 Dec 1;17(8). doi: 10.1093/femsyr/fox091.

PMID:
29186481
10.

Enhanced production of xylitol from xylose by expression of Bacillus subtilis arabinose:H+ symporter and Scheffersomyces stipitis xylose reductase in recombinant Saccharomyces cerevisiae.

Kim H, Lee HS, Park H, Lee DH, Boles E, Chung D, Park YC.

Enzyme Microb Technol. 2017 Dec;107:7-14. doi: 10.1016/j.enzmictec.2017.07.014. Epub 2017 Jul 31.

PMID:
28899489
11.

An artificial transport metabolon facilitates improved substrate utilization in yeast.

Thomik T, Wittig I, Choe JY, Boles E, Oreb M.

Nat Chem Biol. 2017 Nov;13(11):1158-1163. doi: 10.1038/nchembio.2457. Epub 2017 Sep 4.

PMID:
28869594
12.

Establishing a yeast-based screening system for discovery of human GLUT5 inhibitors and activators.

Tripp J, Essl C, Iancu CV, Boles E, Choe JY, Oreb M.

Sci Rep. 2017 Jul 24;7(1):6197. doi: 10.1038/s41598-017-06262-4.

13.

Pathway engineering for the production of heterologous aromatic chemicals and their derivatives in Saccharomyces cerevisiae: bioconversion from glucose.

Gottardi M, Reifenrath M, Boles E, Tripp J.

FEMS Yeast Res. 2017 Jun 1;17(4). doi: 10.1093/femsyr/fox035. Review.

PMID:
28582489
14.

Secretion of 2,3-dihydroxyisovalerate as a limiting factor for isobutanol production in Saccharomyces cerevisiae.

Generoso WC, Brinek M, Dietz H, Oreb M, Boles E.

FEMS Yeast Res. 2017 May 1;17(3). doi: 10.1093/femsyr/fox029.

PMID:
28505306
15.

Polymorphisms in the LAC12 gene explain lactose utilisation variability in Kluyveromyces marxianus strains.

Varela JA, Montini N, Scully D, Van der Ploeg R, Oreb M, Boles E, Hirota J, Akada R, Hoshida H, Morrissey JP.

FEMS Yeast Res. 2017 May 1;17(3). doi: 10.1093/femsyr/fox021.

PMID:
28444380
16.

De novo biosynthesis of trans-cinnamic acid derivatives in Saccharomyces cerevisiae.

Gottardi M, Knudsen JD, Prado L, Oreb M, Branduardi P, Boles E.

Appl Microbiol Biotechnol. 2017 Jun;101(12):4883-4893. doi: 10.1007/s00253-017-8220-x. Epub 2017 Mar 29.

PMID:
28353001
17.

Requirement of a Functional Flavin Mononucleotide Prenyltransferase for the Activity of a Bacterial Decarboxylase in a Heterologous Muconic Acid Pathway in Saccharomyces cerevisiae.

Weber HE, Gottardi M, Brückner C, Oreb M, Boles E, Tripp J.

Appl Environ Microbiol. 2017 May 1;83(10). pii: e03472-16. doi: 10.1128/AEM.03472-16. Print 2017 May 15.

18.

Engineering fungal de novo fatty acid synthesis for short chain fatty acid production.

Gajewski J, Pavlovic R, Fischer M, Boles E, Grininger M.

Nat Commun. 2017 Mar 10;8:14650. doi: 10.1038/ncomms14650.

20.

Parallelised online biomass monitoring in shake flasks enables efficient strain and carbon source dependent growth characterisation of Saccharomyces cerevisiae.

Bruder S, Reifenrath M, Thomik T, Boles E, Herzog K.

Microb Cell Fact. 2016 Jul 25;15(1):127. doi: 10.1186/s12934-016-0526-3.

21.

Simplified CRISPR-Cas genome editing for Saccharomyces cerevisiae.

Generoso WC, Gottardi M, Oreb M, Boles E.

J Microbiol Methods. 2016 Aug;127:203-205. doi: 10.1016/j.mimet.2016.06.020. Epub 2016 Jun 17.

22.

Hxt13, Hxt15, Hxt16 and Hxt17 from Saccharomyces cerevisiae represent a novel type of polyol transporters.

Jordan P, Choe JY, Boles E, Oreb M.

Sci Rep. 2016 Mar 21;6:23502. doi: 10.1038/srep23502.

23.

n-Butanol production in Saccharomyces cerevisiae is limited by the availability of coenzyme A and cytosolic acetyl-CoA.

Schadeweg V, Boles E.

Biotechnol Biofuels. 2016 Feb 24;9:44. doi: 10.1186/s13068-016-0456-7. eCollection 2016.

24.

Comparison of Polyethylene Glycol-Electrolyte Solution vs Polyethylene Glycol-3350 for the Treatment of Fecal Impaction in Pediatric Patients.

Boles EE, Gaines CL, Tillman EM.

J Pediatr Pharmacol Ther. 2015 May-Jun;20(3):210-6. doi: 10.5863/1551-6776-20.3.210.

25.

The genome sequence of the popular hexose-transport-deficient Saccharomyces cerevisiae strain EBY.VW4000 reveals LoxP/Cre-induced translocations and gene loss.

Solis-Escalante D, van den Broek M, Kuijpers NG, Pronk JT, Boles E, Daran JM, Daran-Lapujade P.

FEMS Yeast Res. 2015 Mar;15(2). pii: fou004. doi: 10.1093/femsyr/fou004.

PMID:
25673752
26.

Metabolic engineering of Saccharomyces cerevisiae for production of butanol isomers.

Generoso WC, Schadeweg V, Oreb M, Boles E.

Curr Opin Biotechnol. 2015 Jun;33:1-7. doi: 10.1016/j.copbio.2014.09.004. Epub 2014 Oct 4. Review.

PMID:
25286420
27.

Analysis of factors affecting immune recovery and initial response to tetanus after DTaP vaccination in pediatric allogeneic HSCT patients.

Boles EE, Chiuzan C, Ragucci D, Hudspeth MP.

Pediatr Transplant. 2014 Dec;18(8):882-8. doi: 10.1111/petr.12361. Epub 2014 Sep 22.

PMID:
25243374
28.

Alteration of ROS homeostasis and decreased lifespan in S. cerevisiae elicited by deletion of the mitochondrial translocator FLX1.

Giancaspero TA, Dipalo E, Miccolis A, Boles E, Caselle M, Barile M.

Biomed Res Int. 2014;2014:101286. doi: 10.1155/2014/101286. Epub 2014 May 8.

29.

Engineering of yeast hexose transporters to transport D-xylose without inhibition by D-glucose.

Farwick A, Bruder S, Schadeweg V, Oreb M, Boles E.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5159-64. doi: 10.1073/pnas.1323464111. Epub 2014 Mar 24.

30.

On the role of GAPDH isoenzymes during pentose fermentation in engineered Saccharomyces cerevisiae.

Linck A, Vu XK, Essl C, Hiesl C, Boles E, Oreb M.

FEMS Yeast Res. 2014 May;14(3):389-98. doi: 10.1111/1567-1364.12137. Epub 2014 Feb 13.

31.
32.

Functional characterization of the hexose transporter Hxt13p: an efflux pump that mediates resistance to miltefosine in yeast.

Biswas C, Djordjevic JT, Zuo X, Boles E, Jolliffe KA, Sorrell TC, Chen SC.

Fungal Genet Biol. 2013 Dec;61:23-32. doi: 10.1016/j.fgb.2013.09.005. Epub 2013 Sep 26.

PMID:
24076076
33.

Development of a D-xylose fermenting and inhibitor tolerant industrial Saccharomyces cerevisiae strain with high performance in lignocellulose hydrolysates using metabolic and evolutionary engineering.

Demeke MM, Dietz H, Li Y, Foulquié-Moreno MR, Mutturi S, Deprez S, Den Abt T, Bonini BM, Liden G, Dumortier F, Verplaetse A, Boles E, Thevelein JM.

Biotechnol Biofuels. 2013 Jun 21;6(1):89. doi: 10.1186/1754-6834-6-89.

34.

Biotechnological production of sphingoid bases and their applications.

Schorsch C, Boles E, Schaffer S.

Appl Microbiol Biotechnol. 2013 May;97(10):4301-8. doi: 10.1007/s00253-013-4878-x. Epub 2013 Apr 12.

PMID:
23579731
35.

Production of tetraacetyl phytosphingosine (TAPS) in Wickerhamomyces ciferrii is catalyzed by acetyltransferases Sli1p and Atf2p.

Ter Veld F, Wolff D, Schorsch C, Köhler T, Boles E, Poetsch A.

Appl Microbiol Biotechnol. 2013 Oct;97(19):8537-46. doi: 10.1007/s00253-012-4670-3. Epub 2013 Jan 15.

PMID:
23318835
36.

Isobutanol production from D-xylose by recombinant Saccharomyces cerevisiae.

Brat D, Boles E.

FEMS Yeast Res. 2013 Mar;13(2):241-4. doi: 10.1111/1567-1364.12028. Epub 2013 Jan 16.

37.

Biosynthesis of cis,cis-muconic acid and its aromatic precursors, catechol and protocatechuic acid, from renewable feedstocks by Saccharomyces cerevisiae.

Weber C, Brückner C, Weinreb S, Lehr C, Essl C, Boles E.

Appl Environ Microbiol. 2012 Dec;78(23):8421-30. doi: 10.1128/AEM.01983-12. Epub 2012 Sep 21.

39.

Novel strategies to improve co-fermentation of pentoses with D-glucose by recombinant yeast strains in lignocellulosic hydrolysates.

Oreb M, Dietz H, Farwick A, Boles E.

Bioengineered. 2012 Nov-Dec;3(6):347-51. doi: 10.4161/bioe.21444. Epub 2012 Aug 15.

40.

Amino acid transporter genes are essential for FLO11-dependent and FLO11-independent biofilm formation and invasive growth in Saccharomyces cerevisiae.

Torbensen R, Møller HD, Gresham D, Alizadeh S, Ochmann D, Boles E, Regenberg B.

PLoS One. 2012;7(7):e41272. doi: 10.1371/journal.pone.0041272. Epub 2012 Jul 26.

41.

Metabolic engineering of the non-conventional yeast Pichia ciferrii for production of rare sphingoid bases.

Börgel D, van den Berg M, Hüller T, Andrea H, Liebisch G, Boles E, Schorsch C, van der Pol R, Arink A, Boogers I, van der Hoeven R, Korevaar K, Farwick M, Köhler T, Schaffer S.

Metab Eng. 2012 Jul;14(4):412-26. doi: 10.1016/j.ymben.2012.03.003. Epub 2012 Mar 18.

PMID:
22449569
42.

Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae.

Subtil T, Boles E.

Biotechnol Biofuels. 2012 Mar 16;5:14. doi: 10.1186/1754-6834-5-14.

43.

High-level production of tetraacetyl phytosphingosine (TAPS) by combined genetic engineering of sphingoid base biosynthesis and L-serine availability in the non-conventional yeast Pichia ciferrii.

Schorsch C, Köhler T, Andrea H, Boles E.

Metab Eng. 2012 Mar;14(2):172-84. doi: 10.1016/j.ymben.2011.12.002. Epub 2011 Dec 10.

PMID:
22178746
44.

Uptake of radiolabeled GlcNAc into Saccharomyces cerevisiae via native hexose transporters and its in vivo incorporation into GPI precursors in cells expressing heterologous GlcNAc kinase.

Scarcelli JJ, Colussi PA, Fabre AL, Boles E, Orlean P, Taron CH.

FEMS Yeast Res. 2012 May;12(3):305-16. doi: 10.1111/j.1567-1364.2011.00778.x. Epub 2012 Jan 18.

46.

Over-expression in E. coli and purification of the human OCTN2 transport protein.

Galluccio M, Amelio L, Scalise M, Pochini L, Boles E, Indiveri C.

Mol Biotechnol. 2012 Jan;50(1):1-7. doi: 10.1007/s12033-011-9406-6.

PMID:
21487769
47.

Trends and challenges in the microbial production of lignocellulosic bioalcohol fuels.

Weber C, Farwick A, Benisch F, Brat D, Dietz H, Subtil T, Boles E.

Appl Microbiol Biotechnol. 2010 Jul;87(4):1303-15. doi: 10.1007/s00253-010-2707-z. Epub 2010 Jun 10. Review.

PMID:
20535464
48.

Considerable increase in resveratrol production by recombinant industrial yeast strains with use of rich medium.

Sydor T, Schaffer S, Boles E.

Appl Environ Microbiol. 2010 May;76(10):3361-3. doi: 10.1128/AEM.02796-09. Epub 2010 Mar 26.

49.

Knockout of the DNA ligase IV homolog gene in the sphingoid base producing yeast Pichia ciferrii significantly increases gene targeting efficiency.

Schorsch C, Köhler T, Boles E.

Curr Genet. 2009 Aug;55(4):381-9. doi: 10.1007/s00294-009-0252-z. Epub 2009 May 26.

PMID:
19468735
50.

Identification of a key residue determining substrate affinity in the human glucose transporter GLUT1.

Kasahara T, Maeda M, Boles E, Kasahara M.

Biochim Biophys Acta. 2009 May;1788(5):1051-5. doi: 10.1016/j.bbamem.2009.01.014. Epub 2009 Feb 3.

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