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Items: 19


Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans.

Choi J, Baldwin TM, Wong M, Bolden JE, Fairfax KA, Lucas EC, Cole R, Biben C, Morgan C, Ramsay KA, Ng AP, Kauppi M, Corcoran LM, Shi W, Wilson N, Wilson MJ, Alexander WS, Hilton DJ, de Graaf CA.

Nucleic Acids Res. 2019 Jan 8;47(D1):D780-D785. doi: 10.1093/nar/gky1020.


Transcriptional profiling of eosinophil subsets in interleukin-5 transgenic mice.

Fairfax KA, Bolden JE, Robinson AJ, Lucas EC, Baldwin TM, Ramsay KA, Cole R, Hilton DJ, de Graaf CA.

J Leukoc Biol. 2018 Jul;104(1):195-204. doi: 10.1002/JLB.6MA1117-451R. Epub 2018 May 14.


Identification of a Siglec-F+ granulocyte-macrophage progenitor.

Bolden JE, Lucas EC, Zhou G, O'Sullivan JA, de Graaf CA, McKenzie MD, Di Rago L, Baldwin TM, Shortt J, Alexander WS, Bochner BS, Ritchie ME, Hilton DJ, Fairfax KA.

J Leukoc Biol. 2018 Jul;104(1):123-133. doi: 10.1002/JLB.1MA1217-475R. Epub 2018 Apr 12.


Haemopedia: An Expression Atlas of Murine Hematopoietic Cells.

de Graaf CA, Choi J, Baldwin TM, Bolden JE, Fairfax KA, Robinson AJ, Biben C, Morgan C, Ramsay K, Ng AP, Kauppi M, Kruse EA, Sargeant TJ, Seidenman N, D'Amico A, D'Ombrain MC, Lucas EC, Koernig S, Baz Morelli A, Wilson MJ, Dower SK, Williams B, Heazlewood SY, Hu Y, Nilsson SK, Wu L, Smyth GK, Alexander WS, Hilton DJ.

Stem Cell Reports. 2016 Sep 13;7(3):571-582. doi: 10.1016/j.stemcr.2016.07.007. Epub 2016 Aug 4.


Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.

Ghisi M, Kats L, Masson F, Li J, Kratina T, Vidacs E, Gilan O, Doyle MA, Newbold A, Bolden JE, Fairfax KA, de Graaf CA, Firth M, Zuber J, Dickins RA, Corcoran LM, Dawson MA, Belz GT, Johnstone RW.

Cancer Cell. 2016 Jul 11;30(1):59-74. doi: 10.1016/j.ccell.2016.05.019. Epub 2016 Jun 30.


BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.

Tasdemir N, Banito A, Roe JS, Alonso-Curbelo D, Camiolo M, Tschaharganeh DF, Huang CH, Aksoy O, Bolden JE, Chen CC, Fennell M, Thapar V, Chicas A, Vakoc CR, Lowe SW.

Cancer Discov. 2016 Jun;6(6):612-29. doi: 10.1158/2159-8290.CD-16-0217. Epub 2016 Apr 20.


Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition.

Bolden JE, Tasdemir N, Dow LE, van Es JH, Wilkinson JE, Zhao Z, Clevers H, Lowe SW.

Cell Rep. 2014 Sep 25;8(6):1919-1929. doi: 10.1016/j.celrep.2014.08.025. Epub 2014 Sep 18.


Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities.

Newbold A, Matthews GM, Bots M, Cluse LA, Clarke CJ, Banks KM, Cullinane C, Bolden JE, Christiansen AJ, Dickins RA, Miccolo C, Chiocca S, Kral AM, Ozerova ND, Miller TA, Methot JL, Richon VM, Secrist JP, Minucci S, Johnstone RW.

Mol Cancer Ther. 2013 Dec;12(12):2709-21. doi: 10.1158/1535-7163.MCT-13-0626. Epub 2013 Oct 3.


The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state.

Turkel N, Sahota VK, Bolden JE, Goulding KR, Doggett K, Willoughby LF, Blanco E, Martin-Blanco E, Corominas M, Ellul J, Aigaki T, Richardson HE, Brumby AM.

PLoS Genet. 2013;9(7):e1003627. doi: 10.1371/journal.pgen.1003627. Epub 2013 Jul 18.


Non-cell-autonomous tumor suppression by p53.

Lujambio A, Akkari L, Simon J, Grace D, Tschaharganeh DF, Bolden JE, Zhao Z, Thapar V, Joyce JA, Krizhanovsky V, Lowe SW.

Cell. 2013 Apr 11;153(2):449-60. doi: 10.1016/j.cell.2013.03.020. Epub 2013 Apr 4.


HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses.

Bolden JE, Shi W, Jankowski K, Kan CY, Cluse L, Martin BP, MacKenzie KL, Smyth GK, Johnstone RW.

Cell Death Dis. 2013 Feb 28;4:e519. doi: 10.1038/cddis.2013.9.


Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity.

Chien Y, Scuoppo C, Wang X, Fang X, Balgley B, Bolden JE, Premsrirut P, Luo W, Chicas A, Lee CS, Kogan SC, Lowe SW.

Genes Dev. 2011 Oct 15;25(20):2125-36. doi: 10.1101/gad.17276711. Epub 2011 Oct 6.


Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.

Brumby AM, Goulding KR, Schlosser T, Loi S, Galea R, Khoo P, Bolden JE, Aigaki T, Humbert PO, Richardson HE.

Genetics. 2011 May;188(1):105-25. doi: 10.1534/genetics.111.127910. Epub 2011 Mar 2.


Inducible activation of IFI 16 results in suppression of telomerase activity, growth suppression and induction of cellular senescence.

Clarke CJ, Hii LL, Bolden JE, Johnstone RW.

J Cell Biochem. 2010 Jan 1;109(1):103-12. doi: 10.1002/jcb.22386.


The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.

Ellis L, Bots M, Lindemann RK, Bolden JE, Newbold A, Cluse LA, Scott CL, Strasser A, Atadja P, Lowe SW, Johnstone RW.

Blood. 2009 Jul 9;114(2):380-93. doi: 10.1182/blood-2008-10-182758. Epub 2009 Apr 21.


Enhancing the apoptotic and therapeutic effects of HDAC inhibitors.

Frew AJ, Johnstone RW, Bolden JE.

Cancer Lett. 2009 Aug 8;280(2):125-33. doi: 10.1016/j.canlet.2009.02.042. Epub 2009 Apr 8. Review.


Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist.

Frew AJ, Lindemann RK, Martin BP, Clarke CJ, Sharkey J, Anthony DA, Banks KM, Haynes NM, Gangatirkar P, Stanley K, Bolden JE, Takeda K, Yagita H, Secrist JP, Smyth MJ, Johnstone RW.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11317-22. doi: 10.1073/pnas.0801868105. Epub 2008 Aug 6.


Anticancer activities of histone deacetylase inhibitors.

Bolden JE, Peart MJ, Johnstone RW.

Nat Rev Drug Discov. 2006 Sep;5(9):769-84. Review.


Comparison of the response of saline tonometry and an automated gas tonometry device to a change in CO2.

Noone RB Jr, Bolden JE, Mythen MG, Vaslef SN.

Crit Care Med. 2000 Nov;28(11):3728-33.


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