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Items: 7


The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii.

Lockhart SR, Fothergill AW, Iqbal N, Bolden CB, Grossman NT, Garvey EP, Brand SR, Hoekstra WJ, Schotzinger RJ, Ottinger E, Patterson TF, Wiederhold NP.

Antimicrob Agents Chemother. 2016 Mar 25;60(4):2528-31. doi: 10.1128/AAC.02770-15. Print 2016 Apr.


Candida lusitaniae MICs to the echinocandins are elevated but FKS-mediated resistance is rare.

Lockhart SR, Pham CD, Kuykendall RJ, Bolden CB, Cleveland AA.

Diagn Microbiol Infect Dis. 2016 Jan;84(1):52-54. doi: 10.1016/j.diagmicrobio.2015.08.012. Epub 2015 Aug 28.


Role of FKS Mutations in Candida glabrata: MIC values, echinocandin resistance, and multidrug resistance.

Pham CD, Iqbal N, Bolden CB, Kuykendall RJ, Harrison LH, Farley MM, Schaffner W, Beldavs ZG, Chiller TM, Park BJ, Cleveland AA, Lockhart SR.

Antimicrob Agents Chemother. 2014 Aug;58(8):4690-6. doi: 10.1128/AAC.03255-14. Epub 2014 Jun 2.


Development of a Luminex-based multiplex assay for detection of mutations conferring resistance to Echinocandins in Candida glabrata.

Pham CD, Bolden CB, Kuykendall RJ, Lockhart SR.

J Clin Microbiol. 2014 Mar;52(3):790-5. doi: 10.1128/JCM.03378-13. Epub 2013 Dec 18.


Species identification and antifungal susceptibility testing of Candida bloodstream isolates from population-based surveillance studies in two U.S. cities from 2008 to 2011.

Lockhart SR, Iqbal N, Cleveland AA, Farley MM, Harrison LH, Bolden CB, Baughman W, Stein B, Hollick R, Park BJ, Chiller T.

J Clin Microbiol. 2012 Nov;50(11):3435-42. doi: 10.1128/JCM.01283-12. Epub 2012 Aug 8.


Epidemiologic cutoff values for triazole drugs in Cryptococcus gattii: correlation of molecular type and in vitro susceptibility.

Lockhart SR, Iqbal N, Bolden CB, DeBess EE, Marsden-Haug N, Worhle R, Thakur R, Harris JR; Cryptococcus gattii PNW Public Health Working Group.

Diagn Microbiol Infect Dis. 2012 Jun;73(2):144-8. doi: 10.1016/j.diagmicrobio.2012.02.018. Epub 2012 Apr 10.


Validation of 24-hour flucytosine MIC determination by comparison with 48-hour determination by the Clinical and Laboratory Standards Institute M27-A3 broth microdilution reference method.

Lockhart SR, Bolden CB, Iqbal N, Kuykendall RJ.

J Clin Microbiol. 2011 Dec;49(12):4322-5. doi: 10.1128/JCM.05479-11. Epub 2011 Oct 19.

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