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Items: 24

1.

Inhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma.

Sasi BK, Martines C, Xerxa E, Porro F, Kalkan H, Fazio R, Turkalj S, Bojnik E, Pyrzynska B, Stachura J, Zerrouqi A, Bobrowicz M, Winiarska M, Priebe V, Bertoni F, Mansouri L, Rosenquist R, Efremov DG.

Leukemia. 2019 Mar 14. doi: 10.1038/s41375-019-0442-8. [Epub ahead of print]

PMID:
30872780
2.

Role of miR-15a/miR-16-1 and the TP53 axis in regulating telomerase expression in chronic lymphocytic leukemia.

Rampazzo E, Bojnik E, Trentin L, Bonaldi L, Del Bianco P, Frezzato F, Visentin A, Facco M, Semenzato G, De Rossi A.

Haematologica. 2017 Jul;102(7):e253-e256. doi: 10.3324/haematol.2016.157669. Epub 2017 Apr 6. No abstract available.

3.

Differences in telomere length between sporadic and familial cutaneous melanoma.

Menin C, Bojnik E, Del Bianco P, Elefanti L, Gianesin K, Keppel S, Stagni C, Mocellin S, Vecchiato A, De Rossi A.

Br J Dermatol. 2016 Nov;175(5):937-943. doi: 10.1111/bjd.14652. Epub 2016 Aug 31.

PMID:
27061190
4.

Antinociceptive effect induced by a combination of opioid and neurotensin moieties vs. their hybrid peptide [Ile(9)]PK20 in an acute pain treatment in rodents.

Kleczkowska P, Hermans E, Kosson P, Kowalczyk A, Lesniak A, Pawlik K, Bojnik E, Benyhe S, Nowicka B, Bujalska-Zadrozny M, Misicka A, Lipkowski AW.

Brain Res. 2016 Oct 1;1648(Pt A):172-180. doi: 10.1016/j.brainres.2016.07.039. Epub 2016 Jul 26.

PMID:
27473894
5.

Further Characterization of Hemopressin Peptide Fragments in the Opioid and Cannabinoid Systems.

Szlavicz E, Perera PS, Tomboly C, Helyes Z, Zador F, Benyhe S, Borsodi A, Bojnik E.

Anesth Analg. 2015 Dec;121(6):1488-94. doi: 10.1213/ANE.0000000000000964.

PMID:
26465932
6.

Inhibition of opioid receptor mediated G-protein activity after chronic administration of kynurenic acid and its derivative without direct binding to opioid receptors.

Zador F, Samavati R, Szlavicz E, Tuka B, Bojnik E, Fulop F, Toldi J, Vecsei L, Borsodi A.

CNS Neurol Disord Drug Targets. 2014;13(9):1520-9.

PMID:
25478797
7.

Blood-brain transfer and antinociception of linear and cyclic N-methyl-guanidine and thiourea-enkephalins.

Verbeken M, Wynendaele E, Mauchauffée E, Bracke N, Stalmans S, Bojnik E, Benyhe S, Peremans K, Polis I, Burvenich C, Gjedde A, Hernandez JF, De Spiegeleer B.

Peptides. 2015 Jan;63:10-21. doi: 10.1016/j.peptides.2014.10.010. Epub 2014 Nov 4.

PMID:
25451468
8.

Bioactivity studies on atypical natural opioid hexapeptides processed from proenkephalin (PENK) precursor polypeptides.

Bojnik E, Kleczkowska P, Marron Fernandez de Velasco E, Corbani M, Babos F, Lipkowski AW, Magyar A, Benyhe S.

Comp Biochem Physiol B Biochem Mol Biol. 2014 Aug;174:29-35. doi: 10.1016/j.cbpb.2014.06.002. Epub 2014 Jun 16.

PMID:
24947211
9.

Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL).

Woyach JA, Bojnik E, Ruppert AS, Stefanovski MR, Goettl VM, Smucker KA, Smith LL, Dubovsky JA, Towns WH, MacMurray J, Harrington BK, Davis ME, Gobessi S, Laurenti L, Chang BY, Buggy JJ, Efremov DG, Byrd JC, Johnson AJ.

Blood. 2014 Feb 20;123(8):1207-13. doi: 10.1182/blood-2013-07-515361. Epub 2013 Dec 5.

10.

Identification of Dmt-D-Lys-Phe-Phe-OH as a highly antinociceptive tetrapeptide metabolite of the opioid-neurotensin hybrid peptide PK20.

Kleczkowska P, Bojnik E, Leśniak A, Kosson P, Van den Eynde I, Ballet S, Benyhe S, Tourwé D, Lipkowski AW.

Pharmacol Rep. 2013;65(4):836-46.

11.

Hybrid peptides endomorphin-2/DAMGO: design, synthesis and biological evaluation.

Mollica A, Costante R, Stefanucci A, Pinnen F, Luisi G, Pieretti S, Borsodi A, Bojnik E, Benyhe S.

Eur J Med Chem. 2013 Oct;68:167-77. doi: 10.1016/j.ejmech.2013.07.044. Epub 2013 Aug 11.

PMID:
23974016
12.

Cyclic enkephalins with a diversely substituted guanidine bridge or a thiourea bridge: synthesis, biological and structural evaluations.

Touati-Jallabe Y, Bojnik E, Legrand B, Mauchauffée E, Chung NN, Schiller PW, Benyhe S, Averlant-Petit MC, Martinez J, Hernandez JF.

J Med Chem. 2013 Jul 25;56(14):5964-5973. doi: 10.1021/jm4008592. Epub 2013 Jul 12.

13.

Kainic acid-induced seizure activity alters the mRNA expression and G-protein activation of the opioid/nociceptin receptors in the rat brain cortex.

Turunc Bayrakdar E, Bojnik E, Armagan G, Kanit L, Benyhe S, Borsodi A, Yalcin A.

Epilepsy Res. 2013 Jul;105(1-2):13-9. doi: 10.1016/j.eplepsyres.2012.12.008. Epub 2013 Jan 18.

PMID:
23337899
14.

Synthesis, pharmacological evaluation and conformational investigation of endomorphin-2 hybrid analogues.

Lesma G, Salvadori S, Airaghi F, Bojnik E, Borsodi A, Recca T, Sacchetti A, Balboni G, Silvani A.

Mol Divers. 2013 Feb;17(1):19-31. doi: 10.1007/s11030-012-9399-5. Epub 2012 Nov 4.

PMID:
23124951
15.

Kainic acid-induced changes in the opioid/nociceptin system and the stress/toxicity pathways in the rat hippocampus.

Armagan G, Bojnik E, Turunc E, Kanit L, Gündüz Çinar O, Benyhe S, Borsodi A, Yalcin A.

Neurochem Int. 2012 May;60(6):555-64. doi: 10.1016/j.neuint.2012.02.015. Epub 2012 Feb 21.

PMID:
22382076
16.

The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets.

de Paula Careta F, Gobessi S, Panepucci RA, Bojnik E, Morato de Oliveira F, Mazza Matos D, Falcão RP, Laurenti L, Zago MA, Efremov DG.

Haematologica. 2012 Aug;97(8):1246-54. doi: 10.3324/haematol.2011.054668. Epub 2012 Feb 13.

17.

Changes in the cannabinoid (CB1) receptor expression level and G-protein activation in kainic acid induced seizures.

Bojnik E, Turunç E, Armağan G, Kanıt L, Benyhe S, Yalçın A, Borsodi A.

Epilepsy Res. 2012 Mar;99(1-2):64-8. doi: 10.1016/j.eplepsyres.2011.10.020. Epub 2011 Nov 10.

PMID:
22079489
18.

Alkamides and a neolignan from Echinacea purpurea roots and the interaction of alkamides with G-protein-coupled cannabinoid receptors.

Hohmann J, Rédei D, Forgo P, Szabó P, Freund TF, Haller J, Bojnik E, Benyhe S.

Phytochemistry. 2011 Oct;72(14-15):1848-53. doi: 10.1016/j.phytochem.2011.06.008. Epub 2011 Jul 19.

PMID:
21764086
19.

Phylogenetic diversity and functional efficacy of the C-terminally expressed heptapeptide unit in the opioid precursor polypeptide proenkephalin A.

Bojnik E, Boynik E, Corbani M, Babos F, Magyar A, Borsodi A, Benyhe S.

Neuroscience. 2011 Mar 31;178:56-67. doi: 10.1016/j.neuroscience.2011.01.008. Epub 2011 Jan 15.

PMID:
21241776
20.

Mu opioid receptor mRNA expression, binding, and functional coupling to G-proteins in human epileptic hippocampus.

Cuellar-Herrera M, Velasco AL, Velasco F, Chavez L, Orozco-Suarez S, Armagan G, Turunc E, Bojnik E, Yalcin A, Benyhe S, Borsodi A, Alonso-Vanegas M, Rocha L.

Hippocampus. 2012 Feb;22(2):122-7. doi: 10.1002/hipo.20891. Epub 2010 Nov 3.

PMID:
21049484
21.

Bioinformatic and biochemical studies on the phylogenetic variability of proenkephalin-derived octapeptides.

Bojnik E, Babos F, Magyar A, Borsodi A, Benyhe S.

Neuroscience. 2010 Jan 20;165(2):542-52. doi: 10.1016/j.neuroscience.2009.10.008.

PMID:
19819305
22.

Comparative biochemical and pharmacological characterization of a novel, NOP receptor selective hexapeptide, Ac-RYYRIR-ol.

Bojnik E, Babos F, Fischetti C, Magyar A, Camarda V, Borsodi A, Bajusz S, Calo' G, Benyhe S.

Brain Res Bull. 2010 Mar 16;81(4-5):477-83. doi: 10.1016/j.brainresbull.2009.09.013. Epub 2009 Oct 2.

PMID:
19800951
23.

Selective and high affinity labeling of neuronal and recombinant nociceptin receptors with the hexapeptide radioprobe [(3)H]Ac-RYYRIK-ol.

Bojnik E, Farkas J, Magyar A, Tömböly C, Güçlü U, Gündüz O, Borsodi A, Corbani M, Benyhe S.

Neurochem Int. 2009 Dec;55(7):458-66. doi: 10.1016/j.neuint.2009.04.014. Epub 2009 May 4.

PMID:
19414055
24.

Binding studies of novel, non-mammalian enkephalins, structures predicted from frog and lungfish brain cDNA sequences.

Bojnik E, Magyar A, Tóth G, Bajusz S, Borsodi A, Benyhe S.

Neuroscience. 2009 Jan 23;158(2):867-74. doi: 10.1016/j.neuroscience.2008.09.056. Epub 2008 Oct 10.

PMID:
18977279

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