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Items: 9

1.

Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity.

Zubia A, Ropero S, Otaegui D, Ballestar E, Fraga MF, Boix-Chornet M, Berdasco M, Martinez A, Coll-Mulet L, Gil J, Cossío FP, Esteller M.

Oncogene. 2009 Mar 19;28(11):1477-84. doi: 10.1038/onc.2008.501. Epub 2009 Jan 26.

PMID:
19169274
2.

Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics.

Zelent A, Petrie K, Boix-Chornet M, Melnick AM, Waxman S, Gore SD.

Cancer Res. 2008 Jul 1;68(13):4967-70. doi: 10.1158/0008-5472.CAN-07-6779. No abstract available.

3.

DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia.

Glasow A, Barrett A, Petrie K, Gupta R, Boix-Chornet M, Zhou DC, Grimwade D, Gallagher R, von Lindern M, Waxman S, Enver T, Hildebrandt G, Zelent A.

Blood. 2008 Feb 15;111(4):2374-7. Epub 2007 Nov 9.

4.

Combinatorial effects of splice variants modulate function of Aiolos.

Caballero R, Setien F, Lopez-Serra L, Boix-Chornet M, Fraga MF, Ropero S, Megias D, Alaminos M, Sanchez-Tapia EM, Montoya MC, Esteller M, Gonzalez-Sarmiento R, Ballestar E.

J Cell Sci. 2007 Aug 1;120(Pt 15):2619-30.

5.

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition.

Ropero S, Fraga MF, Ballestar E, Hamelin R, Yamamoto H, Boix-Chornet M, Caballero R, Alaminos M, Setien F, Paz MF, Herranz M, Palacios J, Arango D, Orntoft TF, Aaltonen LA, Schwartz S Jr, Esteller M.

Nat Genet. 2006 May;38(5):566-9. Epub 2006 Apr 16.

PMID:
16642021
6.

Release of hypoacetylated and trimethylated histone H4 is an epigenetic marker of early apoptosis.

Boix-Chornet M, Fraga MF, Villar-Garea A, Caballero R, Espada J, Nuñez A, Casado J, Largo C, Casal JI, Cigudosa JC, Franco L, Esteller M, Ballestar E.

J Biol Chem. 2006 May 12;281(19):13540-7. Epub 2006 Mar 10.

7.

Epigenetic differences arise during the lifetime of monozygotic twins.

Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, Heine-Suñer D, Cigudosa JC, Urioste M, Benitez J, Boix-Chornet M, Sanchez-Aguilera A, Ling C, Carlsson E, Poulsen P, Vaag A, Stephan Z, Spector TD, Wu YZ, Plass C, Esteller M.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10604-9. Epub 2005 Jul 11.

8.

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.

Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Pérez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M.

Nat Genet. 2005 Apr;37(4):391-400. Epub 2005 Mar 13.

PMID:
15765097

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