Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 58


The lipidated connexin mimetic peptide, SRPTEKT-Hdc, is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform.

Cotter ML, Boitano S, Lampe PD, Solan JL, Vagner J, Ek-Vitorin JF, Burt JM.

Am J Physiol Cell Physiol. 2019 Jul 31. doi: 10.1152/ajpcell.00160.2019. [Epub ahead of print]


Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma.

Dy ABC, Arif MZ, Addison KJ, Que LG, Boitano S, Kraft M, Ledford JG.

J Immunol. 2019 Sep 1;203(5):1122-1130. doi: 10.4049/jimmunol.1900546. Epub 2019 Jul 26.


A novel 3D printed radial collimator for x-ray diffraction.

Kowarik S, Bogula L, Boitano S, Carlà F, Pithan H, Schäfer P, Wilming H, Zykov A, Pithan L.

Rev Sci Instrum. 2019 Mar;90(3):035102. doi: 10.1063/1.5063520.


Early life inhalation exposure to mine tailings dust affects lung development.

Witten ML, Chau B, Sáez E, Boitano S, Clark Lantz R.

Toxicol Appl Pharmacol. 2019 Feb 15;365:124-132. doi: 10.1016/j.taap.2019.01.009. Epub 2019 Jan 12.


Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.

Yee MC, Nichols HL, Polley D, Saifeddine M, Pal K, Lee K, Wilson EH, Daines MO, Hollenberg MD, Boitano S, DeFea KA.

Am J Physiol Lung Cell Mol Physiol. 2018 Dec 1;315(6):L1042-L1057. doi: 10.1152/ajplung.00196.2018. Epub 2018 Oct 18.


Protease activated receptor 2 (PAR2) activation causes migraine-like pain behaviors in mice.

Hassler SN, Ahmad FB, Burgos-Vega CC, Boitano S, Vagner J, Price TJ, Dussor G.

Cephalalgia. 2019 Jan;39(1):111-122. doi: 10.1177/0333102418779548. Epub 2018 May 31.


Lipidated connexin mimetic peptides potently inhibit gap junction-mediated Ca2+-wave propagation.

Cotter ML, Boitano S, Vagner J, Burt JM.

Am J Physiol Cell Physiol. 2018 Aug 1;315(2):C141-C154. doi: 10.1152/ajpcell.00156.2017. Epub 2018 Apr 6.


Cerium dioxide (CeO2) nanoparticles decrease arsenite (As(III)) cytotoxicity to 16HBE14o- human bronchial epithelial cells.

Zeng C, Nguyen C, Boitano S, Field JA, Shadman F, Sierra-Alvarez R.

Environ Res. 2018 Jul;164:452-458. doi: 10.1016/j.envres.2018.03.007. Epub 2018 Mar 22.


The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain.

Moy JK, Khoutorsky A, Asiedu MN, Black BJ, Kuhn JL, Barragán-Iglesias P, Megat S, Burton MD, Burgos-Vega CC, Melemedjian OK, Boitano S, Vagner J, Gkogkas CG, Pancrazio JJ, Mogil JS, Dussor G, Sonenberg N, Price TJ.

J Neurosci. 2017 Aug 2;37(31):7481-7499. doi: 10.1523/JNEUROSCI.0220-17.2017. Epub 2017 Jul 3.


Cockroach allergen serine proteinases: Isolation, sequencing and signalling via proteinase-activated receptor-2.

Polley DJ, Mihara K, Ramachandran R, Vliagoftis H, Renaux B, Saifeddine M, Daines MO, Boitano S, Hollenberg MD.

Clin Exp Allergy. 2017 Jul;47(7):946-960. doi: 10.1111/cea.12921. Epub 2017 Apr 27.


The novel PAR2 ligand C391 blocks multiple PAR2 signalling pathways in vitro and in vivo.

Boitano S, Hoffman J, Flynn AN, Asiedu MN, Tillu DV, Zhang Z, Sherwood CL, Rivas CM, DeFea KA, Vagner J, Price TJ.

Br J Pharmacol. 2015 Sep;172(18):4535-4545. doi: 10.1111/bph.13238. Epub 2015 Aug 3.


Protease-activated receptor 2 activation is sufficient to induce the transition to a chronic pain state.

Tillu DV, Hassler SN, Burgos-Vega CC, Quinn TL, Sorge RE, Dussor G, Boitano S, Vagner J, Price TJ.

Pain. 2015 May;156(5):859-67. doi: 10.1097/j.pain.0000000000000125.


A highly potent agonist to protease-activated receptor-2 reveals apical activation of the airway epithelium resulting in Ca2+-regulated ion conductance.

Sherwood CL, Daines MO, Price TJ, Vagner J, Boitano S.

Am J Physiol Cell Physiol. 2014 Oct 15;307(8):C718-26. doi: 10.1152/ajpcell.00257.2014.


Development and evaluation of small peptidomimetic ligands to protease-activated receptor-2 (PAR2) through the use of lipid tethering.

Boitano S, Hoffman J, Tillu DV, Asiedu MN, Zhang Z, Sherwood CL, Wang Y, Dong X, Price TJ, Vagner J.

PLoS One. 2014 Jun 13;9(6):e99140. doi: 10.1371/journal.pone.0099140. eCollection 2014.


Arsenic compromises conducting airway epithelial barrier properties in primary mouse and immortalized human cell cultures.

Sherwood CL, Liguori AE, Olsen CE, Lantz RC, Burgess JL, Boitano S.

PLoS One. 2013 Dec 6;8(12):e82970. doi: 10.1371/journal.pone.0082970. eCollection 2013.


Environmental arsenic exposure, selenium and sputum alpha-1 antitrypsin.

Burgess JL, Kurzius-Spencer M, Poplin GS, Littau SR, Kopplin MJ, Stürup S, Boitano S, Clark Lantz R.

J Expo Sci Environ Epidemiol. 2014 Mar-Apr;24(2):150-5. doi: 10.1038/jes.2013.35. Epub 2013 Jul 10.


Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering.

Flynn AN, Hoffman J, Tillu DV, Sherwood CL, Zhang Z, Patek R, Asiedu MN, Vagner J, Price TJ, Boitano S.

FASEB J. 2013 Apr;27(4):1498-510. doi: 10.1096/fj.12-217323. Epub 2013 Jan 4.


Chronic arsenic exposure in nanomolar concentrations compromises wound response and intercellular signaling in airway epithelial cells.

Sherwood CL, Lantz RC, Boitano S.

Toxicol Sci. 2013 Mar;132(1):222-34. doi: 10.1093/toxsci/kfs331. Epub 2012 Nov 30.


Lanthanide labeling of a potent protease activated receptor-2 agonist for time-resolved fluorescence analysis.

Hoffman J, Flynn AN, Tillu DV, Zhang Z, Patek R, Price TJ, Vagner J, Boitano S.

Bioconjug Chem. 2012 Oct 17;23(10):2098-104. doi: 10.1021/bc300300q. Epub 2012 Oct 8.


Application and validation of an impedance-based real time cell analyzer to measure the toxicity of nanoparticles impacting human bronchial epithelial cells.

Otero-González L, Sierra-Alvarez R, Boitano S, Field JA.

Environ Sci Technol. 2012 Sep 18;46(18):10271-8. doi: 10.1021/es301599f. Epub 2012 Aug 30.


Thrombospondin-1 and angiotensin II inhibit soluble guanylyl cyclase through an increase in intracellular calcium concentration.

Ramanathan S, Mazzalupo S, Boitano S, Montfort WR.

Biochemistry. 2011 Sep 13;50(36):7787-99. doi: 10.1021/bi201060c. Epub 2011 Aug 16.


Cytotoxicity and physicochemical properties of hafnium oxide nanoparticles.

Field JA, Luna-Velasco A, Boitano SA, Shadman F, Ratner BD, Barnes C, Sierra-Alvarez R.

Chemosphere. 2011 Sep;84(10):1401-7. doi: 10.1016/j.chemosphere.2011.04.067. Epub 2011 May 24.


The protease-activated receptor-2-specific agonists 2-aminothiazol-4-yl-LIGRL-NH2 and 6-aminonicotinyl-LIGRL-NH2 stimulate multiple signaling pathways to induce physiological responses in vitro and in vivo.

Flynn AN, Tillu DV, Asiedu MN, Hoffman J, Vagner J, Price TJ, Boitano S.

J Biol Chem. 2011 May 27;286(21):19076-88. doi: 10.1074/jbc.M110.185264. Epub 2011 Apr 5.


Arsenic alters ATP-dependent Ca²+ signaling in human airway epithelial cell wound response.

Sherwood CL, Lantz RC, Burgess JL, Boitano S.

Toxicol Sci. 2011 May;121(1):191-206. doi: 10.1093/toxsci/kfr044. Epub 2011 Feb 25.


Alternaria alternata serine proteases induce lung inflammation and airway epithelial cell activation via PAR2.

Boitano S, Flynn AN, Sherwood CL, Schulz SM, Hoffman J, Gruzinova I, Daines MO.

Am J Physiol Lung Cell Mol Physiol. 2011 Apr;300(4):L605-14. doi: 10.1152/ajplung.00359.2010. Epub 2011 Feb 4.


Potent agonists of the protease activated receptor 2 (PAR2).

Boitano S, Flynn AN, Schulz SM, Hoffman J, Price TJ, Vagner J.

J Med Chem. 2011 Mar 10;54(5):1308-13. doi: 10.1021/jm1013049. Epub 2011 Feb 4.


Site-specific connexin phosphorylation is associated with reduced heterocellular communication between smooth muscle and endothelium.

Straub AC, Johnstone SR, Heberlein KR, Rizzo MJ, Best AK, Boitano S, Isakson BE.

J Vasc Res. 2010;47(4):277-86. doi: 10.1159/000265562. Epub 2009 Dec 16.


Tracheobronchial protease inhibitors, body surface area burns, and mortality in smoke inhalation.

Kurzius-Spencer M, Foster K, Littau S, Richey KJ, Clark BM, Sherrill D, Boitano S, Caruso DM, Burgess JL.

J Burn Care Res. 2009 Sep-Oct;30(5):824-31. doi: 10.1097/BCR.0b013e3181b47ee8.


Arsenic upregulates MMP-9 and inhibits wound repair in human airway epithelial cells.

Olsen CE, Liguori AE, Zong Y, Lantz RC, Burgess JL, Boitano S.

Am J Physiol Lung Cell Mol Physiol. 2008 Aug;295(2):L293-302. doi: 10.1152/ajplung.00134.2007. Epub 2008 Jun 6.


Bordetella bronchiseptica responses to physiological reactive nitrogen and oxygen stresses.

Omsland A, Miranda KM, Friedman RL, Boitano S.

FEMS Microbiol Lett. 2008 Jul;284(1):92-101. doi: 10.1111/j.1574-6968.2008.01181.x. Epub 2008 May 6.


Trichloroethylene disrupts cardiac gene expression and calcium homeostasis in rat myocytes.

Caldwell PT, Thorne PA, Johnson PD, Boitano S, Runyan RB, Selmin O.

Toxicol Sci. 2008 Jul;104(1):135-43. doi: 10.1093/toxsci/kfn078. Epub 2008 Apr 14.


Tracheobronchial markers of lung injury in smoke inhalation victims.

Kurzius-Spencer M, Foster K, Littau S, Richey KJ, Clark BM, Sherrill D, Goodman RB, Boitano S, Burgess JL.

J Burn Care Res. 2008 Mar-Apr;29(2):311-8. doi: 10.1097/BCR.0b013e3181667991.


Pulmonary biomarkers based on alterations in protein expression after exposure to arsenic.

Lantz RC, Lynch BJ, Boitano S, Poplin GS, Littau S, Tsaprailis G, Burgess JL.

Environ Health Perspect. 2007 Apr;115(4):586-91. Epub 2007 Jan 8.


Intestinal barrier failure during experimental necrotizing enterocolitis: protective effect of EGF treatment.

Clark JA, Doelle SM, Halpern MD, Saunders TA, Holubec H, Dvorak K, Boitano SA, Dvorak B.

Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G938-49. Epub 2006 Jun 22.


Extracellular matrix-driven alveolar epithelial cell differentiation in vitro.

Olsen CO, Isakson BE, Seedorf GJ, Lubman RL, Boitano S.

Exp Lung Res. 2005 Jun;31(5):461-82.


Cell-cell interactions in regulating lung function.

Boitano S, Safdar Z, Welsh DG, Bhattacharya J, Koval M.

Am J Physiol Lung Cell Mol Physiol. 2004 Sep;287(3):L455-9. Review.


Cell-cell communication in heterocellular cultures of alveolar epithelial cells.

Isakson BE, Seedorf GJ, Lubman RL, Evans WH, Boitano S.

Am J Respir Cell Mol Biol. 2003 Nov;29(5):552-61. Epub 2003 May 14.


Heterocellular cultures of pulmonary alveolar epithelial cells grown on laminin-5 supplemented matrix.

Isakson BE, Seedorf GJ, Lubman RL, Boitano S.

In Vitro Cell Dev Biol Anim. 2002 Sep;38(8):443-9.


Modulation of pulmonary alveolar type II cell phenotype and communication by extracellular matrix and KGF.

Isakson BE, Lubman RL, Seedorf GJ, Boitano S.

Am J Physiol Cell Physiol. 2001 Oct;281(4):C1291-9.


Connexin mimetic peptides: specific inhibitors of gap-junctional intercellular communication.

Evans WH, Boitano S.

Biochem Soc Trans. 2001 Aug;29(Pt 4):606-12. Review.


Intercellular Ca2+ signaling in alveolar epithelial cells through gap junctions and by extracellular ATP.

Isakson BE, Evans WH, Boitano S.

Am J Physiol Lung Cell Mol Physiol. 2001 Feb;280(2):L221-8.


From the extracellular matrix to cell and tissue function in the alveolar epithelium.

Boitano S.

Am J Physiol Lung Cell Mol Physiol. 2001 Feb;280(2):L189-90. No abstract available.


Connexin mimetic peptides reversibly inhibit Ca(2+) signaling through gap junctions in airway cells.

Boitano S, Evans WH.

Am J Physiol Lung Cell Mol Physiol. 2000 Oct;279(4):L623-30.


Sequence-specific antibodies to connexins block intercellular calcium signaling through gap junctions.

Boitano S, Dirksen ER, Evans WH.

Cell Calcium. 1998 Jan;23(1):1-9.


Supplemental Content

Loading ...
Support Center