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Items: 1 to 50 of 96

1.

Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6-dependent mechanism.

Zhang L, Deng M, Lu A, Chen Y, Chen Y, Wu C, Tan Z, Boini KM, Yang T, Zhu Q, Wang L.

J Cell Mol Med. 2019 Dec;23(12):8139-8150. doi: 10.1111/jcmm.14684. Epub 2019 Sep 29.

2.

Podocyte NLRP3 Inflammasome Activation and Formation by Adipokine Visfatin.

Koka S, Xia M, Zhang C, Zhang Y, Li PL, Boini KM.

Cell Physiol Biochem. 2019;53(2):355-365. doi: 10.33594/000000143.

3.

High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction.

Singh GB, Zhang Y, Boini KM, Koka S.

Int J Mol Sci. 2019 Jul 22;20(14). pii: E3570. doi: 10.3390/ijms20143570.

4.

Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene.

Zhang P, Guan Y, Chen J, Li X, McConnell BK, Zhou W, Boini KM, Zhang Y.

Cell Death Dis. 2018 Nov 19;9(12):1145. doi: 10.1038/s41419-018-1197-2.

5.

Cathepsin B-Mediated NLRP3 Inflammasome Formation and Activation in Angiotensin II -Induced Hypertensive Mice: Role of Macrophage Digestion Dysfunction.

Lian D, Lai J, Wu Y, Wang L, Chen Y, Zhang Y, Boini KM, Huang Y, Chen Y.

Cell Physiol Biochem. 2018;50(4):1585-1600. doi: 10.1159/000494656. Epub 2018 Oct 25.

6.

Tricyclic antidepressant amitriptyline inhibits autophagic flux and prevents tube formation in vascular endothelial cells.

Guan Y, Li X, Umetani M, Boini KM, Li PL, Zhang Y.

Basic Clin Pharmacol Toxicol. 2019 Apr;124(4):370-384. doi: 10.1111/bcpt.13146. Epub 2018 Nov 15.

PMID:
30311396
7.

Post-stroke mRNA expression profile of MMPs: effect of genetic deletion of MMP-12.

Nalamolu KR, Chelluboina B, Magruder IB, Fru DN, Mohandass A, Venkatesh I, Klopfenstein JD, Pinson DM, Boini KM, Veeravalli KK.

Stroke Vasc Neurol. 2018 Mar 9;3(3):153-159. doi: 10.1136/svn-2018-000142. eCollection 2018 Sep.

8.

Hypoxia inducible factor-1α mediates the profibrotic effect of albumin in renal tubular cells.

Hu J, Wang W, Zhang F, Li PL, Boini KM, Yi F, Li N.

Sci Rep. 2017 Nov 20;7(1):15878. doi: 10.1038/s41598-017-15972-8.

9.

Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction.

Boini KM, Hussain T, Li PL, Koka S.

Cell Physiol Biochem. 2017;44(1):152-162. doi: 10.1159/000484623. Epub 2017 Nov 6.

10.

Infusion of Valproic Acid Into the Renal Medulla Activates Stem Cell Population and Attenuates Salt-Sensitive Hypertension in Dahl S Rats.

Wang Z, Zhu Q, Wang W, Yi F, Li PL, Boini KM, Li N.

Cell Physiol Biochem. 2017;42(3):1264-1273. doi: 10.1159/000478955. Epub 2017 Jul 11.

11.

Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia.

Koka S, Xia M, Chen Y, Bhat OM, Yuan X, Boini KM, Li PL.

Redox Biol. 2017 Oct;13:336-344. doi: 10.1016/j.redox.2017.06.004. Epub 2017 Jun 15.

12.

Inhibition of microRNA-429 in the renal medulla increased salt sensitivity of blood pressure in Sprague Dawley rats.

Zhu Q, Hu J, Wang L, Wang W, Wang Z, Li PL, Boini KM, Li N.

J Hypertens. 2017 Sep;35(9):1872-1880. doi: 10.1097/HJH.0000000000001373.

13.

Contribution of guanine nucleotide exchange factor Vav2 to NLRP3 inflammasome activation in mouse podocytes during hyperhomocysteinemia.

Conley SM, Abais-Battad JM, Yuan X, Zhang Q, Boini KM, Li PL.

Free Radic Biol Med. 2017 May;106:236-244. doi: 10.1016/j.freeradbiomed.2017.02.027. Epub 2017 Feb 11.

14.

Implication of CD38 gene in autophagic degradation of collagen I in mouse coronary arterial myocytes.

Bao JX, Zhang QF, Wang M, Xia M, Boini KM, Gulbins E, Zhang Y, Li PL.

Front Biosci (Landmark Ed). 2017 Jan 1;22:558-569.

15.

Sphingolipids in obesity and related complications.

Boini KM, Xia M, Koka S, Gehr TW, Li PL.

Front Biosci (Landmark Ed). 2017 Jan 1;22:96-116. Review.

16.

Activation of NLRP3 inflammasomes in mouse hepatic stellate cells during Schistosoma J. infection.

Meng N, Xia M, Lu YQ, Wang M, Boini KM, Li PL, Tang WX.

Oncotarget. 2016 Jun 28;7(26):39316-39331. doi: 10.18632/oncotarget.10044.

17.

Inflammasome Activation in Chronic Glomerular Diseases.

Conley SM, Abais JM, Boini KM, Li PL.

Curr Drug Targets. 2017;18(9):1019-1029. doi: 10.2174/1389450117666160817103435. Review.

18.

Characterization and Activation of NLRP3 Inflammasomes in the Renal Medulla in Mice.

Xia M, Abais JM, Koka S, Meng N, Gehr TW, Boini KM, Li PL.

Kidney Blood Press Res. 2016;41(2):208-21. doi: 10.1159/000443424. Epub 2016 Mar 25.

19.

Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene.

Boini KM, Xia M, Koka S, Gehr TW, Li PL.

Oncotarget. 2016 Apr 5;7(14):19031-44. doi: 10.18632/oncotarget.8023.

20.

Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis.

Chen Y, Li X, Boini KM, Pitzer AL, Gulbins E, Zhang Y, Li PL.

Biochim Biophys Acta. 2015 Feb;1853(2):396-408. doi: 10.1016/j.bbamcr.2014.11.012. Epub 2014 Nov 15.

21.

Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector?

Abais JM, Xia M, Zhang Y, Boini KM, Li PL.

Antioxid Redox Signal. 2015 May 1;22(13):1111-29. doi: 10.1089/ars.2014.5994. Epub 2015 Jan 19. Review.

22.

Inhibition of hyperhomocysteinemia-induced inflammasome activation and glomerular sclerosis by NLRP3 gene deletion.

Xia M, Conley SM, Li G, Li PL, Boini KM.

Cell Physiol Biochem. 2014;34(3):829-41. doi: 10.1159/000363046. Epub 2014 Aug 20.

23.

Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein (TXNIP) during hyperhomocysteinemia.

Abais JM, Xia M, Li G, Chen Y, Conley SM, Gehr TW, Boini KM, Li PL.

J Biol Chem. 2014 Sep 26;289(39):27159-68. doi: 10.1074/jbc.M114.567537. Epub 2014 Aug 19.

24.

Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin.

Xia M, Boini KM, Abais JM, Xu M, Zhang Y, Li PL.

Am J Pathol. 2014 May;184(5):1617-28. doi: 10.1016/j.ajpath.2014.01.032. Epub 2014 Mar 13.

25.

Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing.

Boini KM, Xia M, Abais JM, Li G, Pitzer AL, Gehr TW, Zhang Y, Li PL.

Biochim Biophys Acta. 2014 May;1843(5):836-45. doi: 10.1016/j.bbamcr.2014.01.033. Epub 2014 Feb 5.

26.

Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis.

Li X, Zhang Y, Xia M, Gulbins E, Boini KM, Li PL.

PLoS One. 2014 Jan 27;9(1):e87552. doi: 10.1371/journal.pone.0087552. eCollection 2014.

27.

Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis.

Li X, Xu M, Pitzer AL, Xia M, Boini KM, Li PL, Zhang Y.

J Mol Med (Berl). 2014 May;92(5):473-85. doi: 10.1007/s00109-014-1120-y. Epub 2014 Jan 25.

28.

Defective autophagosome trafficking contributes to impaired autophagic flux in coronary arterial myocytes lacking CD38 gene.

Zhang Y, Xu M, Xia M, Li X, Boini KM, Wang M, Gulbins E, Ratz PH, Li PL.

Cardiovasc Res. 2014 Apr 1;102(1):68-78. doi: 10.1093/cvr/cvu011. Epub 2014 Jan 20.

29.

Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes.

Xiong J, Xia M, Xu M, Zhang Y, Abais JM, Li G, Riebling CR, Ritter JK, Boini KM, Li PL.

J Cell Mol Med. 2013 Dec;17(12):1598-607. doi: 10.1111/jcmm.12173. Epub 2013 Nov 17.

30.

Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia.

Abais JM, Xia M, Li G, Gehr TW, Boini KM, Li PL.

Free Radic Biol Med. 2014 Feb;67:211-20. doi: 10.1016/j.freeradbiomed.2013.10.009. Epub 2013 Oct 16.

31.

Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes.

Wei YM, Li X, Xu M, Abais JM, Chen Y, Riebling CR, Boini KM, Li PL, Zhang Y.

Cell Physiol Biochem. 2013;31(6):925-37. doi: 10.1159/000350111. Epub 2013 Jun 18.

32.

Protective role of growth hormone against hyperhomocysteinemia-induced glomerular injury.

Li C, Xia M, Abais JM, Liu X, Li N, Boini KM, Li PL.

Naunyn Schmiedebergs Arch Pharmacol. 2013 Jun;386(6):551-61. doi: 10.1007/s00210-013-0848-1. Epub 2013 Mar 27.

33.

Attenuation by statins of membrane raft-redox signaling in coronary arterial endothelium.

Wei YM, Li X, Xiong J, Abais JM, Xia M, Boini KM, Zhang Y, Li PL.

J Pharmacol Exp Ther. 2013 May;345(2):170-9. doi: 10.1124/jpet.112.201442. Epub 2013 Feb 22.

34.

Regulation of renin release via cyclic ADP-ribose-mediated signaling: evidence from mice lacking CD38 gene.

Xiong J, Xia M, Yi F, Abais JM, Li N, Boini KM, Li PL.

Cell Physiol Biochem. 2013;31(1):44-55. doi: 10.1159/000343348. Epub 2013 Jan 14.

35.

Intracellular two-phase Ca2+ release and apoptosis controlled by TRP-ML1 channel activity in coronary arterial myocytes.

Xu M, Li X, Walsh SW, Zhang Y, Abais JM, Boini KM, Li PL.

Am J Physiol Cell Physiol. 2013 Mar 1;304(5):C458-66. doi: 10.1152/ajpcell.00342.2012. Epub 2013 Jan 2.

36.

TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice.

Li X, Han WQ, Boini KM, Xia M, Zhang Y, Li PL.

J Mol Med (Berl). 2013 Jan;91(1):25-36. doi: 10.1007/s00109-012-0968-y. Epub 2012 Oct 24.

37.

NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia.

Abais JM, Zhang C, Xia M, Liu Q, Gehr TW, Boini KM, Li PL.

Antioxid Redox Signal. 2013 May 1;18(13):1537-48. doi: 10.1089/ars.2012.4666. Epub 2012 Dec 10.

38.
39.

Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia.

Zhang C, Boini KM, Xia M, Abais JM, Li X, Liu Q, Li PL.

Hypertension. 2012 Jul;60(1):154-62. doi: 10.1161/HYPERTENSIONAHA.111.189688. Epub 2012 May 29.

40.

Requirement of translocated lysosomal V1 H(+)-ATPase for activation of membrane acid sphingomyelinase and raft clustering in coronary endothelial cells.

Xu M, Xia M, Li XX, Han WQ, Boini KM, Zhang F, Zhang Y, Ritter JK, Li PL.

Mol Biol Cell. 2012 Apr;23(8):1546-57. doi: 10.1091/mbc.E11-09-0821. Epub 2012 Feb 22.

41.

Lysosome fusion to the cell membrane is mediated by the dysferlin C2A domain in coronary arterial endothelial cells.

Han WQ, Xia M, Xu M, Boini KM, Ritter JK, Li NJ, Li PL.

J Cell Sci. 2012 Mar 1;125(Pt 5):1225-34. doi: 10.1242/jcs.094565. Epub 2012 Feb 20.

42.

Implication of CD38 gene in podocyte epithelial-to-mesenchymal transition and glomerular sclerosis.

Boini KM, Xia M, Xiong J, Li C, Payne LP, Li PL.

J Cell Mol Med. 2012 Aug;16(8):1674-85. doi: 10.1111/j.1582-4934.2011.01462.x.

43.

Novel role for SGK3 in glucose homeostasis revealed in SGK3/Akt2 double-null mice.

Yao LJ, McCormick JA, Wang J, Yang KY, Kidwai A, Colussi GL, Boini KM, Birnbaum MJ, Lang F, German MS, Pearce D.

Mol Endocrinol. 2011 Dec;25(12):2106-18. doi: 10.1210/me.2010-0329. Epub 2011 Oct 6.

44.

Acid sphingomyelinase gene deficiency ameliorates the hyperhomocysteinemia-induced glomerular injury in mice.

Boini KM, Xia M, Li C, Zhang C, Payne LP, Abais JM, Poklis JL, Hylemon PB, Li PL.

Am J Pathol. 2011 Nov;179(5):2210-9. doi: 10.1016/j.ajpath.2011.07.019. Epub 2011 Sep 3.

45.

EMD638683, a novel SGK inhibitor with antihypertensive potency.

Ackermann TF, Boini KM, Beier N, Scholz W, Fuchss T, Lang F.

Cell Physiol Biochem. 2011;28(1):137-46. doi: 10.1159/000331722. Epub 2011 Aug 16.

46.

Reversal by growth hormone of homocysteine-induced epithelial-to-mesenchymal transition through membrane raft-redox signaling in podocytes.

Li CX, Xia M, Han WQ, Li XX, Zhang C, Boini KM, Liu XC, Li PL.

Cell Physiol Biochem. 2011;27(6):691-702. doi: 10.1159/000330078. Epub 2011 Jun 17.

47.

Epithelial-to-mesenchymal transition in podocytes mediated by activation of NADPH oxidase in hyperhomocysteinemia.

Zhang C, Xia M, Boini KM, Li CX, Abais JM, Li XX, Laperle LA, Li PL.

Pflugers Arch. 2011 Sep;462(3):455-67. doi: 10.1007/s00424-011-0981-y. Epub 2011 Jun 7.

48.

Cell volume, the serum and glucocorticoid inducible kinase 1 and the liver.

Lang PA, Graf D, Boini KM, Lang KS, Klingel K, Kandolf R, Lang F.

Z Gastroenterol. 2011 Jun;49(6):713-9. doi: 10.1055/s-0031-1273425. Epub 2011 Jun 1.

PMID:
21638237
49.

PKB/SGK-resistant GSK3 enhances phosphaturia and calciuria.

Föller M, Kempe DS, Boini KM, Pathare G, Siraskar B, Capuano P, Alesutan I, Sopjani M, Stange G, Mohebbi N, Bhandaru M, Ackermann TF, Judenhofer MS, Pichler BJ, Biber J, Wagner CA, Lang F.

J Am Soc Nephrol. 2011 May;22(5):873-80. doi: 10.1681/ASN.2010070757. Epub 2011 Apr 14.

50.

Hypothyroidism of gene-targeted mice lacking Kcnq1.

Fröhlich H, Boini KM, Seebohm G, Strutz-Seebohm N, Ureche ON, Föller M, Eichenmüller M, Shumilina E, Pathare G, Singh AK, Seidler U, Pfeifer KE, Lang F.

Pflugers Arch. 2011 Jan;461(1):45-52. doi: 10.1007/s00424-010-0890-5. Epub 2010 Oct 27.

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