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Items: 1 to 50 of 73

1.

Influence of inflammasome pathway activation in macrophages on the matrix metalloproteinase expression of human hepatic stellate cells.

Robert S, Gicquel T, Bodin A, Fautrel A, Barreto E, Victoni T, Lagente V, Boichot E.

Int Immunopharmacol. 2019 Jul;72:12-20. doi: 10.1016/j.intimp.2019.03.060. Epub 2019 Apr 4.

PMID:
30954791
2.

Purinergic receptors: new targets for the treatment of gout and fibrosis.

Gicquel T, Le Daré B, Boichot E, Lagente V.

Fundam Clin Pharmacol. 2017 Apr;31(2):136-146. doi: 10.1111/fcp.12256. Epub 2016 Dec 30. Review.

3.

Involvement of matrix metalloproteinases (MMPs) and inflammasome pathway in molecular mechanisms of fibrosis.

Robert S, Gicquel T, Victoni T, Valença S, Barreto E, Bailly-Maître B, Boichot E, Lagente V.

Biosci Rep. 2016 Jul 15;36(4). pii: e00360. doi: 10.1042/BSR20160107. Print 2016 Aug. Review.

4.

Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1β or TNF-α Release from Human Hepatic Stellate Cells.

Robert S, Gicquel T, Bodin A, Lagente V, Boichot E.

PLoS One. 2016 Apr 5;11(4):e0153118. doi: 10.1371/journal.pone.0153118. eCollection 2016.

5.

Roflumilast n-oxide associated with PGE2 prevents the neutrophil elastase-induced production of chemokines by epithelial cells.

Victoni T, Gicquel T, Bodin A, Daude M, Tenor H, Valença S, Devillier P, Porto LC, Lagente V, Boichot E.

Int Immunopharmacol. 2016 Jan;30:1-8. doi: 10.1016/j.intimp.2015.11.019. Epub 2015 Nov 21.

6.

IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages.

Gicquel T, Robert S, Loyer P, Victoni T, Bodin A, Ribault C, Gleonnec F, Couillin I, Boichot E, Lagente V.

FASEB J. 2015 Oct;29(10):4162-73. doi: 10.1096/fj.14-267393. Epub 2015 Jun 26.

PMID:
26116704
7.

Involvement of purinergic receptors and NOD-like receptor-family protein 3-inflammasome pathway in the adenosine triphosphate-induced cytokine release from macrophages.

Gicquel T, Victoni T, Fautrel A, Robert S, Gleonnec F, Guezingar M, Couillin I, Catros V, Boichot E, Lagente V.

Clin Exp Pharmacol Physiol. 2014 Apr;41(4):279-86. doi: 10.1111/1440-1681.12214.

PMID:
24472059
8.

Roflumilast N-oxide prevents cytokine secretion induced by cigarette smoke combined with LPS through JAK/STAT and ERK1/2 inhibition in airway epithelial cells.

Victoni T, Gleonnec F, Lanzetti M, Tenor H, Valença S, Porto LC, Lagente V, Boichot E.

PLoS One. 2014 Jan 8;9(1):e85243. doi: 10.1371/journal.pone.0085243. eCollection 2014.

9.

Role of matrix metalloproteinases in the inflammatory process of respiratory diseases.

Lagente V, Boichot E.

J Mol Cell Cardiol. 2010 Mar;48(3):440-4. doi: 10.1016/j.yjmcc.2009.09.017. Epub 2009 Oct 8. Review.

PMID:
19818795
10.

Macrophage metalloelastase (MMP-12) as a target for inflammatory respiratory diseases.

Lagente V, Le Quement C, Boichot E.

Expert Opin Ther Targets. 2009 Mar;13(3):287-95. doi: 10.1517/14728220902751632 . Review.

PMID:
19236151
11.

The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke.

Le Quément C, Guénon I, Gillon JY, Valença S, Cayron-Elizondo V, Lagente V, Boichot E.

Br J Pharmacol. 2008 Jul;154(6):1206-15. doi: 10.1038/bjp.2008.180. Epub 2008 May 19.

12.

MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells.

Le Quément C, Guénon I, Gillon JY, Lagente V, Boichot E.

Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1076-84. doi: 10.1152/ajplung.00489.2007. Epub 2008 Apr 4.

13.

Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.

Doz E, Noulin N, Boichot E, Guénon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I.

J Immunol. 2008 Jan 15;180(2):1169-78.

14.

Effects of depletion of neutrophils or macrophages on the inflammatory response induced by metalloelastase (MMP-12) in mice airways.

Nénan S, Boichot E, Planquois JM, Berna P, Hitier S, Bénard T, Lagente V, Bertrand CP.

Eur J Pharmacol. 2008 Jan 28;579(1-3):374-81. Epub 2007 Oct 25.

PMID:
18001704
15.

Influence of early neutrophil depletion on MMPs/TIMP-1 balance in bleomycin-induced lung fibrosis.

Manoury B, Nénan S, Guénon I, Lagente V, Boichot E.

Int Immunopharmacol. 2007 Jul;7(7):900-11. Epub 2007 Mar 15.

PMID:
17499192
16.

Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.

Nénan S, Lagente V, Planquois JM, Hitier S, Berna P, Bertrand CP, Boichot E.

Eur J Pharmacol. 2007 Mar 15;559(1):75-81. Epub 2006 Dec 12.

PMID:
17234180
17.

TIMP-1 is a key factor of fibrogenic response to bleomycin in mouse lung.

Manoury B, Caulet-Maugendre S, Guénon I, Lagente V, Boichot E.

Int J Immunopathol Pharmacol. 2006 Jul-Sep;19(3):471-87.

PMID:
17026855
18.

Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice.

Manoury B, Nenan S, Guenon I, Boichot E, Planquois JM, Bertrand CP, Lagente V.

J Inflamm (Lond). 2006 Feb 22;3:2.

19.

Role of matrix metalloproteinases in the development of airway inflammation and remodeling.

Lagente V, Manoury B, Nénan S, Le Quément C, Martin-Chouly C, Boichot E.

Braz J Med Biol Res. 2005 Oct;38(10):1521-30. Epub 2005 Sep 6. Review.

20.

Macrophage elastase (MMP-12): a pro-inflammatory mediator?

Nénan S, Boichot E, Lagente V, Bertrand CP.

Mem Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:167-72. Epub 2005 Jun 14. Review.

21.

Selective PDE4 inhibitors as potent anti-inflammatory drugs for the treatment of airway diseases.

Lagente V, Martin-Chouly C, Boichot E, Martins MA, Silva PM.

Mem Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:131-6. Epub 2005 Jun 14. Review.

22.

Analysis of the inflammatory response induced by rhMMP-12 catalytic domain instilled in mouse airways.

Nénan S, Planquois JM, Berna P, De Mendez I, Hitier S, Shapiro SD, Boichot E, Lagente V, Bertrand CP.

Int Immunopharmacol. 2005 Mar;5(3):511-24.

PMID:
15683848
23.

The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis.

Manoury B, Nenan S, Leclerc O, Guenon I, Boichot E, Planquois JM, Bertrand CP, Lagente V.

Respir Res. 2005 Jan 21;6:11.

24.

Interactions of tachykinin receptor antagonists with lipopolysaccharide-induced airway inflammation in mice.

Veron M, Guenon I, Nenan S, Emonds-Alt X, Advenier C, Lagente V, Boichot E.

Clin Exp Pharmacol Physiol. 2004 Sep;31(9):634-40.

PMID:
15479172
25.

A nitric oxide-releasing salbutamol elicits potent relaxant and anti-inflammatory activities.

Lagente V, Naline E, Guenon I, Corbel M, Boichot E, Burgaud JL, Del Soldato P, Advenier C.

J Pharmacol Exp Ther. 2004 Jul;310(1):367-75. Epub 2004 Apr 14.

PMID:
15084649
26.

Enhancement of gelatinase activity during development of subepithelial fibrosis in a murine model of asthma.

Corbel M, Caulet-Maugendre S, Germain N, Lagente V, Boichot E.

Clin Exp Allergy. 2003 May;33(5):696-704.

PMID:
12752601
27.

Imbalance between matrix metalloproteinases (MMP-9 and MMP-2) and tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in acute respiratory distress syndrome patients.

Lanchou J, Corbel M, Tanguy M, Germain N, Boichot E, Theret N, Clement B, Lagente V, Malledant Y.

Crit Care Med. 2003 Feb;31(2):536-42.

PMID:
12576963
28.

Involvement of gelatinases (MMP-2 and MMP-9) in the development of airway inflammation and pulmonary fibrosis.

Corbel M, Belleguic C, Boichot E, Lagente V.

Cell Biol Toxicol. 2002;18(1):51-61. Review.

PMID:
11991086
29.

Effect of the cannabinoid receptor ligand, WIN 55,212-2, on superoxide anion and TNF-alpha production by human mononuclear cells.

Germain N, Boichot E, Advenier C, Berdyshev EV, Lagente V.

Int Immunopharmacol. 2002 Mar;2(4):537-43.

PMID:
11962732
30.

Increased release of matrix metalloproteinase-9 in the plasma of acute severe asthmatic patients.

Belleguic C, Corbel M, Germain N, Léna H, Boichot E, Delaval PH, Lagente V.

Clin Exp Allergy. 2002 Feb;32(2):217-23.

PMID:
11929485
32.

Effects of PDE4 inhibitors on lipopolysaccharide-induced priming of superoxide anion production from human mononuclear cells.

Germain N, Corbel M, Belleguic C, Boichot E, Lagente V.

Mediators Inflamm. 2001 Jun;10(3):117-23.

33.
34.

Inhibition of inflammatory cell recruitment by the tachykinin NK(3)-receptor antagonist, SR 142801, in a murine model of asthma.

Nénan S, Germain N, Lagente V, Emonds-Alt X, Advenier C, Boichot E.

Eur J Pharmacol. 2001 Jun 15;421(3):201-5.

PMID:
11516437
35.

Repeated endotoxin exposure induces interstitial fibrosis associated with enhanced gelatinase (MMP-2 and MMP-9) activity.

Corbel M, Theret N, Caulet-Maugendre S, Germain N, Lagente V, Clement B, Boichot E.

Inflamm Res. 2001 Mar;50(3):129-35.

PMID:
11339500
36.

Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat.

Corbel M, Caulet-Maugendre S, Germain N, Molet S, Lagente V, Boichot E.

J Pathol. 2001 Apr;193(4):538-45.

PMID:
11276015
37.

Reduction of matrix metalloproteinase-9 activity by the selective phosphodiesterase 4 inhibitor, RP 73-401 in sensitized mice.

Belleguic C, Corbel M, Germain N, Boichot E, Delaval P, Lagente V.

Eur J Pharmacol. 2000 Sep 22;404(3):369-73.

PMID:
10996602
38.

Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury.

Corbel M, Boichot E, Lagente V.

Braz J Med Biol Res. 2000 Jul;33(7):749-54. Review.

39.

Reduced airway hyperresponsiveness by phosphodiesterase 3 and 4 inhibitors in guinea-pigs.

Germain N, Boichot E, Planquois JM, Lagente V.

Mediators Inflamm. 1999;8(3):153-7.

40.

Anti-inflammatory activities of a new series of selective phosphodiesterase 4 inhibitors derived from 9-benzyladenine.

Boichot E, Wallace JL, Germain N, Corbel M, Lugnier C, Lagente V, Bourguignon JJ.

J Pharmacol Exp Ther. 2000 Feb;292(2):647-53.

PMID:
10640302
41.

Endotoxin-induced acute lung injury in rats. Role of insulin.

Boichot E, Sannomiya P, Escofier N, Germain N, Fortes ZB, Lagente V.

Pulm Pharmacol Ther. 1999;12(5):285-90.

PMID:
10545284
43.

Effects of interleukin-10 and modulators of cyclic AMP formation on endotoxin-induced inflammation in rat lung.

Escofier N, Boichot E, Germain N, Silva PM, Martins MA, Lagente V.

Fundam Clin Pharmacol. 1999;13(1):96-101.

PMID:
10027094
44.

Selective phosphodiesterase inhibitors modulate the activity of alveolar macrophages from sensitized guinea-pigs.

Germain N, Bertin B, Legendre A, Martin B, Lagente V, Payne A, Boichot E.

Eur Respir J. 1998 Dec;12(6):1334-9.

45.

In vitro-induced human airway hyperresponsiveness to bradykinin.

Molimard M, Naline E, Boichot E, Devillier P, Lagente V, Bégaud B, Advenier C.

Eur Respir J. 1998 Dec;12(6):1301-6.

46.

Effects of SR 140333 and SR 48968 on antigen and substance P-induced activation of guinea-pig alveolar macrophages.

Boichot E, Germain N, Emonds-Alt X, Advenier C, Lagente V.

Clin Exp Allergy. 1998 Oct;28(10):1299-305.

PMID:
9824398
47.

Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice.

Berdyshev E, Boichot E, Corbel M, Germain N, Lagente V.

Life Sci. 1998;63(8):PL125-9.

PMID:
9718090
48.
49.

Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells.

Berdyshev EV, Boichot E, Germain N, Allain N, Anger JP, Lagente V.

Eur J Pharmacol. 1997 Jul 9;330(2-3):231-40.

PMID:
9253958
50.

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