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Items: 1 to 50 of 89

1.

An Overview of the Potential Therapeutic Applications of CO-Releasing Molecules.

Ismailova A, Kuter D, Bohle DS, Butler IS.

Bioinorg Chem Appl. 2018 Aug 12;2018:8547364. doi: 10.1155/2018/8547364. eCollection 2018. Review.

2.

Generation of a Mn(IV)-Peroxo or Mn(III)-Oxo-Mn(III) Species upon Oxygenation of Mono- and Binuclear Thiolate-Ligated Mn(II) Complexes.

Lee CM, Wu WY, Chiang MH, Bohle DS, Lee GH.

Inorg Chem. 2017 Sep 5;56(17):10559-10569. doi: 10.1021/acs.inorgchem.7b01513. Epub 2017 Aug 21.

PMID:
28825825
3.

Effects of Inorganic Arsenic, Methylated Arsenicals, and Arsenobetaine on Atherosclerosis in the Mouse Model and the Role of As3mt-Mediated Methylation.

Negro Silva LF, Lemaire M, Lemarié CA, Plourde D, Bolt AM, Chiavatti C, Bohle DS, Slavkovich V, Graziano JH, Lehoux S, Mann KK.

Environ Health Perspect. 2017 Jul 5;125(7):077001. doi: 10.1289/EHP806.

4.

Solution and Solid State Correlations of Antimalarial Drug Actions: NMR and Crystallographic Studies of Drug Interactions with a Heme Model.

Dodd EL, Tazoo D, Bohle DS.

Inorg Chem. 2017 Jul 17;56(14):7803-7810. doi: 10.1021/acs.inorgchem.7b00526. Epub 2017 Jun 26.

PMID:
28650618
5.

{Fe(NO)(2)(9) Dinitrosyl Iron Complex Acting as a Vehicle for the NO Radical.

Ke CH, Chen CH, Tsai ML, Wang HC, Tsai FT, Chiang YW, Shih WC, Bohle DS, Liaw WF.

J Am Chem Soc. 2017 Jan 11;139(1):67-70. doi: 10.1021/jacs.6b11454. Epub 2016 Dec 28.

PMID:
28030770
6.

Crystal Structure Analysis of the Repair of Iron Centers Protein YtfE and Its Interaction with NO.

Lo FC, Hsieh CC, Maestre-Reyna M, Chen CY, Ko TP, Horng YC, Lai YC, Chiang YW, Chou CM, Chiang CH, Huang WN, Lin YH, Bohle DS, Liaw WF.

Chemistry. 2016 Jul 4;22(28):9768-76. doi: 10.1002/chem.201600990. Epub 2016 Jun 1.

PMID:
27246459
7.

3-Iodo-4-aminoquinoline derivative sensitises resistant strains of Plasmodium falciparum to chloroquine.

Edaye S, Tazoo D, Bohle DS, Georges E.

Int J Antimicrob Agents. 2016 Jun;47(6):482-5. doi: 10.1016/j.ijantimicag.2016.03.016. Epub 2016 Apr 26.

PMID:
27211211
8.

Surface Characterization of Hematin Anhydride: A Comparison between Two Different Synthesis Methods.

Guerra ED, Bohle DS, Cerruti M.

Langmuir. 2016 May 10;32(18):4479-84. doi: 10.1021/acs.langmuir.6b00908. Epub 2016 Apr 27.

PMID:
27089176
9.

Seven-Membered Ring Nucleoside Analogues: Stereoselective Synthesis and Studies on Their Conformational Properties.

Habibian M, Martínez-Montero S, Portella G, Chua Z, Bohle DS, Orozco M, Damha MJ.

Org Lett. 2015 Nov 6;17(21):5416-9. doi: 10.1021/acs.orglett.5b02769. Epub 2015 Oct 22.

PMID:
26492193
10.

3-Halo Chloroquine Derivatives Overcome Plasmodium falciparum Chloroquine Resistance Transporter-Mediated Drug Resistance in P. falciparum.

Edaye S, Tazoo D, Bohle DS, Georges E.

Antimicrob Agents Chemother. 2015 Dec;59(12):7891-3. doi: 10.1128/AAC.01139-15. Epub 2015 Oct 5.

11.

Stabilizing and Activating Nitrogen Catenates.

Bohle DS, Chua Z, Singer Hobbs M, Perepichka I, Waked A.

Chemistry. 2015 Sep 21;21(39):13739-47. doi: 10.1002/chem.201501241. Epub 2015 Aug 7.

PMID:
26256118
12.

Nitric Oxide Catalysis of Diazene E/Z Isomerization.

Bohle DS, Rosadiuk KA.

Inorg Chem. 2015 Aug 3;54(15):7145-51. doi: 10.1021/acs.inorgchem.5b00476. Epub 2015 Jul 22.

PMID:
26200101
13.

When push comes to shove: unravelling the mechanism and scope of nonemissive meso-unsaturated BODIPY dyes.

Lincoln R, Greene LE, Bain C, Flores-Rizo JO, Bohle DS, Cosa G.

J Phys Chem B. 2015 Apr 2;119(13):4758-65. doi: 10.1021/acs.jpcb.5b02080. Epub 2015 Mar 18.

PMID:
25751527
14.

Switching the Z/E selectivity in the palladium(II)-catalyzed decarboxylative Heck arylations of trans-cinnamaldehydes by solvent.

Ban SR, Wang HN, Toader V, Bohle DS, Li CJ.

Org Lett. 2014 Dec 19;16(24):6282-5. doi: 10.1021/ol502955r. Epub 2014 Dec 3.

PMID:
25469946
15.

Activation of nitrogen Brønsted acids: synthesis and reactivity of a new class of nitrogen acid complexes.

Bohle DS, Chua Z.

Inorg Chem. 2014 Oct 20;53(20):11160-72. doi: 10.1021/ic5017033. Epub 2014 Oct 3.

PMID:
25279421
16.

Orienting the heterocyclic periphery: a structural model for chloroquine's antimalarial activity.

Dodd EL, Bohle DS.

Chem Commun (Camb). 2014 Nov 18;50(89):13765-8. doi: 10.1039/c4cc05328a.

PMID:
25250883
17.

The novel arsenical darinaparsin is transported by cystine importing systems.

Garnier N, Redstone GG, Dahabieh MS, Nichol JN, del Rincon SV, Gu Y, Bohle DS, Sun Y, Conklin DS, Mann KK, Miller WH Jr.

Mol Pharmacol. 2014 Apr;85(4):576-85. doi: 10.1124/mol.113.089433. Epub 2014 Jan 15.

18.

Plasmodium products contribute to severe malarial anemia by inhibiting erythropoietin-induced proliferation of erythroid precursors.

Thawani N, Tam M, Bellemare MJ, Bohle DS, Olivier M, de Souza JB, Stevenson MM.

J Infect Dis. 2014 Jan 1;209(1):140-9. doi: 10.1093/infdis/jit417. Epub 2013 Aug 6.

PMID:
23922378
19.

Optimization of malaria detection based on third harmonic generation imaging of hemozoin.

Tripathy U, Giguère-Bisson M, Sangji MH, Bellemare MJ, Bohle DS, Georges E, Wiseman PW.

Anal Bioanal Chem. 2013 Jun;405(16):5431-40. doi: 10.1007/s00216-013-6985-z. Epub 2013 May 7.

PMID:
23649925
20.

Facile dimethylarsenic exchange and pyramidal inversion in its cysteine and glutathione adducts.

Bohle DS, Gu Y.

Org Biomol Chem. 2013 Apr 28;11(16):2578-81. doi: 10.1039/c3ob40268a.

PMID:
23503635
21.

E/Z oxime isomerism in PhC(NOH)CN.

Bohle DS, Chua Z, Perepichka I, Rosadiuk K.

Chemistry. 2013 Mar 25;19(13):4223-9. doi: 10.1002/chem.201203357. Epub 2013 Feb 10.

PMID:
23400927
22.

Soluble diamagnetic model for malaria pigment: coordination chemistry of gallium(III)protoporphyrin-IX.

Bohle DS, Dodd EL, Pinter TB, Stillman MJ.

Inorg Chem. 2012 Oct 15;51(20):10747-61. doi: 10.1021/ic301106g. Epub 2012 Oct 2.

PMID:
23030718
23.

Alterations in bone and erythropoiesis in hemolytic anemia: comparative study in bled, phenylhydrazine-treated and Plasmodium-infected mice.

Moreau R, Tshikudi Malu D, Dumais M, Dalko E, Gaudreault V, Roméro H, Martineau C, Kevorkova O, Dardon JS, Dodd EL, Bohle DS, Scorza T.

PLoS One. 2012;7(9):e46101. doi: 10.1371/journal.pone.0046101. Epub 2012 Sep 28.

24.

Structure of malaria pigment and related propanoate-linked metalloporphyrin dimers.

Bohle DS, Dodd EL, Stephens PW.

Chem Biodivers. 2012 Sep;9(9):1891-902. doi: 10.1002/cbdv.201200033. Review.

PMID:
22976978
25.

E versus Z diazeniumdiolation of acetoacetate-derived carbanions.

Arulsamy N, Bohle DS, Holman CL, Perepichka I.

J Org Chem. 2012 Sep 7;77(17):7313-8. doi: 10.1021/jo301025k. Epub 2012 Aug 14.

PMID:
22852822
26.

[Gallium(III) protoporphyrin IX]2: a soluble diamagnetic model for malaria pigment.

Bohle DS, Dodd EL.

Inorg Chem. 2012 Apr 16;51(8):4411-3. doi: 10.1021/ic2027303. Epub 2012 Mar 23.

PMID:
22439683
27.

Spectroscopic and theoretical studies of Ga(III)protoporphyrin-IX and its reactions with myoglobin.

Pinter TB, Dodd EL, Bohle DS, Stillman MJ.

Inorg Chem. 2012 Mar 19;51(6):3743-53. doi: 10.1021/ic202731g. Epub 2012 Feb 28.

PMID:
22372462
28.

Unexpected 5,6,7,8,9,10-hexahydro-6,6-pentamethylenephenanthridines and 2,3,4,5-tetrahydro-4,4-tetramethylene-1H-cyclopenta[c]quinolines from Skraup-Doebner-Von Miller quinoline synthesis and their implications for the mechanism of that reaction.

Fotie J, Kemami Wangun HV, Fronczek FR, Massawe N, Bhattarai BT, Rhodus JL, Singleton TA, Bohle DS.

J Org Chem. 2012 Mar 16;77(6):2784-90. doi: 10.1021/jo202681r. Epub 2012 Feb 28.

PMID:
22335838
29.

Interaction of quinoline antimalarial drugs with ferriprotoporphyrin IX, a solid state spectroscopy study.

Asghari-Khiavi M, Vongsvivut J, Perepichka I, Mechler A, Wood BR, McNaughton D, Bohle DS.

J Inorg Biochem. 2011 Dec;105(12):1662-9. doi: 10.1016/j.jinorgbio.2011.08.005. Epub 2011 Aug 12.

PMID:
22079977
30.

Soluble synthetic analogues of malaria pigment: structure of mesohematin anhydride and its interaction with chloroquine in solution.

Bohle DS, Dodd EL, Kosar AJ, Sharma L, Stephens PW, Suárez L, Tazoo D.

Angew Chem Int Ed Engl. 2011 Jun 27;50(27):6151-4. doi: 10.1002/anie.201100910. Epub 2011 May 3. No abstract available.

PMID:
21542075
31.

Toward understanding the chloroquine action at the molecular level in antimalarial therapy--X-ray absorption studies in acetic acid solution.

Walczak MS, Lawniczak-Jablonska K, Wolska A, Sikora M, Sienkiewicz A, Suárez L, Kosar AJ, Bellemare MJ, Bohle DS.

J Phys Chem B. 2011 Apr 21;115(15):4419-26. doi: 10.1021/jp106790r. Epub 2011 Mar 24.

PMID:
21434658
32.

N-H activation in N-nitropropionamide: coordination chemistry of a primary nitroamide.

Bohle DS, Chua Z.

Inorg Chem. 2011 Apr 4;50(7):3135-40. doi: 10.1021/ic200090u. Epub 2011 Mar 10.

PMID:
21391665
33.

Understanding chloroquine action at the molecular level in antimalarial therapy: X-ray absorption studies in dimethyl sulfoxide solution.

Walczak MS, Lawniczak-Jablonska K, Wolska A, Sienkiewicz A, Suárez L, Kosar AJ, Bohle DS.

J Phys Chem B. 2011 Feb 10;115(5):1145-50. doi: 10.1021/jp106793u. Epub 2010 Dec 29.

PMID:
21190356
34.

4-(8-Eth-oxy-2,3-dihydro-1H-cyclo-penta-[c]quinolin-4-yl)butane-1-peroxol.

Fotie J, Fronczek CF, Burns KA, Fronczek FR, Bain C, Bohle DS, Poudeu FP.

Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 16;66(Pt 7):o1660. doi: 10.1107/S1600536810021781.

35.

Synthetic Plasmodium-like hemozoin activates the immune response: a morphology - function study.

Jaramillo M, Bellemare MJ, Martel C, Shio MT, Contreras AP, Godbout M, Roger M, Gaudreault E, Gosselin J, Bohle DS, Olivier M.

PLoS One. 2009 Sep 9;4(9):e6957. doi: 10.1371/journal.pone.0006957.

36.

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.

Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M.

PLoS Pathog. 2009 Aug;5(8):e1000559. doi: 10.1371/journal.ppat.1000559. Epub 2009 Aug 21. Erratum in: PLoS Pathog. 2009 Sep;5(9). doi: 10.1371/annotation/abca067d-b82b-4de6-93c5-0fcc38e3df05. Tiemi Shio, Marina [corrected to Shio, Marina Tiemi].

37.

Autofluorescence of condensed heme aggregates in malaria pigment and its synthetic equivalent hematin anhydride (beta-hematin).

Bellemare MJ, Bohle DS, Brosseau CN, Georges E, Godbout M, Kelly J, Leimanis ML, Leonelli R, Olivier M, Smilkstein M.

J Phys Chem B. 2009 Jun 18;113(24):8391-401. doi: 10.1021/jp8104375.

PMID:
19472980
38.

Cationic and anionic surface binding sites on nanocrystalline zinc oxide: surface influence on photoluminescence and photocatalysis.

Bohle DS, Spina CJ.

J Am Chem Soc. 2009 Apr 1;131(12):4397-404. doi: 10.1021/ja808663b.

PMID:
19265384
39.
40.

Base controlled polydiazeniumdiolation of 4-heptanone and a new water layer structure.

Arulsamy N, Bohle DS, Chuang CH, Moore RC.

J Org Chem. 2008 Oct 17;73(20):8077-80. doi: 10.1021/jo801583f. Epub 2008 Sep 20. Erratum in: J Org Chem. 2009 Aug 7;74(15):5766.

PMID:
18803420
41.

Kinetics and mechanism of nucleophilic addition to nitric oxide: secondary amine diazeniumdiolation.

Bohle DS, Smith KN.

Inorg Chem. 2008 May 19;47(10):3925-7. doi: 10.1021/ic800027m. Epub 2008 Apr 12.

PMID:
18407623
42.

Sensitive detection of malaria infection by third harmonic generation imaging.

Bélisle JM, Costantino S, Leimanis ML, Bellemare MJ, Bohle DS, Georges E, Wiseman PW.

Biophys J. 2008 Feb 15;94(4):L26-8. Epub 2007 Dec 7.

43.

Fluorescent diethylcarbamazine analogues: sites of accumulation in Brugia malayi.

Junnila A, Bohle DS, Prichard R, Perepichka I, Spina C.

Bioconjug Chem. 2007 Nov-Dec;18(6):1818-23. Epub 2007 Oct 10.

PMID:
17927226
44.

The relationship of oxygen binding and peroxide sites and the fluorescent properties of zinc oxide semiconductor nanocrystals.

Bohle DS, Spina CJ.

J Am Chem Soc. 2007 Oct 17;129(41):12380-1. Epub 2007 Sep 22. No abstract available.

PMID:
17887759
45.

Trypanocidal and antileishmanial dihydrochelerythrine derivatives from Garcinia lucida.

Fotie J, Bohle DS, Olivier M, Adelaida Gomez M, Nzimiro S.

J Nat Prod. 2007 Oct;70(10):1650-3. Epub 2007 Sep 20.

PMID:
17880175
46.

Methylation of sydnone N-oxides: kinetic and thermodynamic control in the alkylation site of an electron-rich heterocycle.

Bohle DS, McQuade LE, Perepichka I, Zhang L.

J Org Chem. 2007 May 11;72(10):3625-31. Epub 2007 Apr 18.

PMID:
17439281
47.

The evolution and refinement of a chemical biology training program: A Canadian perspective.

Bohle DS.

ACS Chem Biol. 2006 Sep 19;1(8):485-6. No abstract available.

PMID:
17168531
48.

Synthesis of new cyclic dialkoxy disulfides.

Eghbali N, Bohle DS, Harpp DN.

J Org Chem. 2006 Aug 18;71(17):6659-61.

PMID:
16901166
49.
50.

Multi-frequency high-field EPR study of iron centers in malarial pigments.

Sienkiewicz A, Krzystek J, Vileno B, Chatain G, Kosar AJ, Bohle DS, Forró L.

J Am Chem Soc. 2006 Apr 12;128(14):4534-5.

PMID:
16594665

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