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Items: 9


SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development.

Xu Q, Xiang Y, Wang Q, Wang L, Brind'Amour J, Bogutz AB, Zhang Y, Zhang B, Yu G, Xia W, Du Z, Huang C, Ma J, Zheng H, Li Y, Liu C, Walker CL, Jonasch E, Lefebvre L, Wu M, Lorincz MC, Li W, Li L, Xie W.

Nat Genet. 2019 May;51(5):844-856. doi: 10.1038/s41588-019-0398-7. Epub 2019 Apr 29.


Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage.

Bogutz AB, Oh-McGinnis R, Jacob KJ, Ho-Lau R, Gu T, Gertsenstein M, Nagy A, Lefebvre L.

PLoS Genet. 2018 Aug 10;14(8):e1007587. doi: 10.1371/journal.pgen.1007587. eCollection 2018 Aug.


Development and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA).

Richard Albert J, Koike T, Younesy H, Thompson R, Bogutz AB, Karimi MM, Lorincz MC.

BMC Genomics. 2018 Jun 15;19(1):463. doi: 10.1186/s12864-018-4835-2.


Maternal DNA Methylation Regulates Early Trophoblast Development.

Branco MR, King M, Perez-Garcia V, Bogutz AB, Caley M, Fineberg E, Lefebvre L, Cook SJ, Dean W, Hemberger M, Reik W.

Dev Cell. 2016 Jan 25;36(2):152-63. doi: 10.1016/j.devcel.2015.12.027.


Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST.

Kelsey AD, Yang C, Leung D, Minks J, Dixon-McDougall T, Baldry SE, Bogutz AB, Lefebvre L, Brown CJ.

Genome Biol. 2015 Oct 2;16:208. doi: 10.1186/s13059-015-0774-2.


Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2.

MacIsaac JL, Bogutz AB, Morrissy AS, Lefebvre L.

Nucleic Acids Res. 2012 Feb;40(4):1523-35. doi: 10.1093/nar/gkr871. Epub 2011 Nov 3.


An extended domain of Kcnq1ot1 silencing revealed by an imprinted fluorescent reporter.

Jones MJ, Bogutz AB, Lefebvre L.

Mol Cell Biol. 2011 Jul;31(14):2827-37. doi: 10.1128/MCB.01435-10. Epub 2011 May 16.


Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction.

Oh-McGinnis R, Bogutz AB, Lefebvre L.

Dev Biol. 2011 Mar 15;351(2):277-86. doi: 10.1016/j.ydbio.2011.01.008. Epub 2011 Jan 14.


Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome.

Oh-McGinnis R, Bogutz AB, Lee KY, Higgins MJ, Lefebvre L.

BMC Dev Biol. 2010 May 11;10:50. doi: 10.1186/1471-213X-10-50.

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