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Items: 1 to 50 of 305

1.

Determinants of Serum- and Plasma Sphingosine-1-Phosphate Concentrations in a Healthy Study Group.

Daum G, Winkler M, Moritz E, Müller T, Geffken M, von Lucadou M, Haddad M, Peine S, Böger RH, Larena-Avellaneda A, Debus ES, Gräler M, Schwedhelm E.

TH Open. 2020 Jan 23;4(1):e12-e19. doi: 10.1055/s-0040-1701205. eCollection 2020 Jan.

2.

Muscle phenotype of AGAT- and GAMT-deficient mice after simvastatin exposure.

Sasani A, Hornig S, Grzybowski R, Cordts K, Hanff E, Tsikas D, Böger R, Gerloff C, Isbrandt D, Neu A, Schwedhelm E, Choe CU.

Amino Acids. 2020 Jan;52(1):73-85. doi: 10.1007/s00726-019-02812-4. Epub 2019 Dec 18.

PMID:
31853708
3.

Low homoarginine/SDMA ratio is associated with poor short- and long-term outcome after stroke in two prospective studies.

Choe CU, Lezius S, Cordts K, Gerloff C, Böger RH, Schwedhelm E, Grant PJ.

Neurol Sci. 2020 Jan;41(1):149-153. doi: 10.1007/s10072-019-04058-0. Epub 2019 Sep 3.

PMID:
31482247
4.

The P2-receptor-mediated Ca2+ signalosome of the human pulmonary endothelium - implications for pulmonary arterial hypertension.

Hennigs JK, Lüneburg N, Stage A, Schmitz M, Körbelin J, Harbaum L, Matuszcak C, Mienert J, Bokemeyer C, Böger RH, Kiefmann R, Klose H.

Purinergic Signal. 2019 Sep;15(3):299-311. doi: 10.1007/s11302-019-09674-1. Epub 2019 Aug 8.

5.

Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy.

Cordts K, Seelig D, Lund N, Carrier L, Böger RH, Avanesov M, Tahir E, Schwedhelm E, Patten M.

Biomolecules. 2019 Jul 13;9(7). pii: E277. doi: 10.3390/biom9070277.

6.

Asymmetric Dimethylarginine at Sea Level Is a Predictive Marker of Hypoxic Pulmonary Arterial Hypertension at High Altitude.

Siques P, Brito J, Schwedhelm E, Pena E, León-Velarde F, De La Cruz JJ, Böger RH, Hannemann J.

Front Physiol. 2019 May 27;10:651. doi: 10.3389/fphys.2019.00651. eCollection 2019.

7.

The protective effect of dronedarone on the structure and mechanical properties of the aorta in hypertensive rats by decreasing the concentration of symmetric dimethylarginine (SDMA).

Quintana-Villamandos B, González MDC, Delgado-Martos MJ, Gutiérrez-Arzapalo PY, Böger RH, Lüneburg N, Muñoz D, Delgado-Baeza E.

PLoS One. 2019 May 21;14(5):e0216820. doi: 10.1371/journal.pone.0216820. eCollection 2019.

8.

Exercise training prior to night shift work improves physical work capacity and arterial stiffness.

Schäfer C, Mayr B, Müller EE, Augner C, Hannemann J, Böger RH, Schönfelder M, Niebauer J.

Eur J Prev Cardiol. 2019 May 8:2047487319848196. doi: 10.1177/2047487319848196. [Epub ahead of print] No abstract available.

PMID:
31067130
9.

Dronedarone induces regression of coronary artery remodeling related to better global antioxidant status.

Quintana-Villamandos B, Pazó-Sayós L, Arribas SM, Rodríguez-Rodríguez P, Böger RH, Lüneburg N, Delgado-Baeza E, González MC.

Hypertens Res. 2019 Oct;42(10):1485-1494. doi: 10.1038/s41440-019-0257-z. Epub 2019 Apr 16.

PMID:
30992541
10.

Effect of ranolazine on plasma arginine derivatives and urinary isoprostane 8-iso-PGF in patients with myocardial infarction in the randomized RIMINI-Trial.

Schwemer TF, Deutscher N, Diermann N, Böger R, Schwedhelm E, Blankenberg S, Friedrich FW.

Sci Rep. 2019 Apr 5;9(1):5708. doi: 10.1038/s41598-019-42239-1.

11.

Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA2DS2-VASc score in three cross-sectional studies.

Cordts K, Grzybowski R, Lezius S, Lüneburg N, Atzler D, Neu A, Hornig S, Böger RH, Gerloff C, Magnus T, Thomalla G, Schwedhelm E, Grant PJ, Choe CU.

J Neurol Sci. 2019 Feb 15;397:156-161. doi: 10.1016/j.jns.2018.12.037. Epub 2018 Dec 31.

PMID:
30640152
12.

Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival.

Winkler MS, Nierhaus A, Rösler G, Lezius S, Harlandt O, Schwedhelm E, Böger RH, Kluge S.

Crit Care. 2018 Sep 19;22(1):216. doi: 10.1186/s13054-018-2090-1.

13.

Cross-Sectional Associations between Homoarginine, Intermediate Phenotypes, and Atrial Fibrillation in the Community-The Gutenberg Health Study.

Niekamp C, Atzler D, Ojeda FM, Sinning CR, Lackner KJ, Böger RH, Munzel T, Beutel ME, Schmidtmann I, Pfeiffer N, Leuschner A, Blankenberg S, Wild PS, Zeller T, Schwedhelm E, Schnabel RB.

Biomolecules. 2018 Aug 30;8(3). pii: E86. doi: 10.3390/biom8030086.

14.

Low-Circulating Homoarginine is Associated with Dilatation and Decreased Function of the Left Ventricle in the General Population.

Bahls M, Atzler D, Markus MRP, Friedrich N, Böger RH, Völzke H, Felix SB, Schwedhelm E, Dörr M.

Biomolecules. 2018 Jul 30;8(3). pii: E63. doi: 10.3390/biom8030063.

15.

Development and implementation of a cell-based assay to discover agonists of the nuclear receptor REV-ERBα.

Hering Y, Berthier A, Duez H, Lefebvre P, Deprez B, Gribbon P, Wolf M, Reinshagen J, Halley F, Hannemann J, Böger R, Staels B, Gul S.

J Biol Methods. 2018 Jun 25;5(3):e94. doi: 10.14440/jbm.2018.244. eCollection 2018.

16.

Long-Term Intermittent Work at High Altitude: Right Heart Functional and Morphological Status and Associated Cardiometabolic Factors.

Brito J, Siques P, López R, Romero R, León-Velarde F, Flores K, Lüneburg N, Hannemann J, Böger RH.

Front Physiol. 2018 Mar 22;9:248. doi: 10.3389/fphys.2018.00248. eCollection 2018.

17.

Relationship between exercise intervention and NO pathway in patients with heart failure with preserved ejection fraction.

Baldassarri F, Schwedhelm E, Atzler D, Böger RH, Cordts K, Haller B, Pressler A, Müller S, Suchy C, Wachter R, Düngen HD, Hasenfuss G, Pieske B, Halle M, Edelmann F, Duvinage A.

Biomarkers. 2018 Sep;23(6):540-550. doi: 10.1080/1354750X.2018.1460762. Epub 2018 Apr 12.

PMID:
29619838
18.

Asymmetric and Symmetric Dimethylarginines are Markers of Delayed Cerebral Ischemia and Neurological Outcome in Patients with Subarachnoid Hemorrhage.

Appel D, Seeberger M, Schwedhelm E, Czorlich P, Goetz AE, Böger RH, Hannemann J.

Neurocrit Care. 2018 Aug;29(1):84-93. doi: 10.1007/s12028-018-0520-1.

PMID:
29560598
19.

Cognitive performance of 20 healthy humans supplemented with L-homoarginine for 4 weeks.

Schönhoff M, Weineck G, Hoppe J, Hornig S, Cordts K, Atzler D, Gerloff C, Böger R, Neu A, Schwedhelm E, Choe CU.

J Clin Neurosci. 2018 Apr;50:237-241. doi: 10.1016/j.jocn.2018.01.035. Epub 2018 Feb 1.

PMID:
29396070
20.

Plasma Nitrate and Incidence of Cardiovascular Disease and All-Cause Mortality in the Community: The Framingham Offspring Study.

Maas R, Xanthakis V, Göen T, Müller J, Schwedhelm E, Böger RH, Vasan RS.

J Am Heart Assoc. 2017 Nov 18;6(11). pii: e006224. doi: 10.1161/JAHA.117.006224. Erratum in: J Am Heart Assoc. 2017 Dec 2;6(12):e004222.

21.

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.

Boege Y, Malehmir M, Healy ME, Bettermann K, Lorentzen A, Vucur M, Ahuja AK, Böhm F, Mertens JC, Shimizu Y, Frick L, Remouchamps C, Mutreja K, Kähne T, Sundaravinayagam D, Wolf MJ, Rehrauer H, Koppe C, Speicher T, Padrissa-Altés S, Maire R, Schattenberg JM, Jeong JS, Liu L, Zwirner S, Boger R, Hüser N, Davis RJ, Müllhaupt B, Moch H, Schulze-Bergkamen H, Clavien PA, Werner S, Borsig L, Luther SA, Jost PJ, Weinlich R, Unger K, Behrens A, Hillert L, Dillon C, Di Virgilio M, Wallach D, Dejardin E, Zender L, Naumann M, Walczak H, Green DR, Lopes M, Lavrik I, Luedde T, Heikenwalder M, Weber A.

Cancer Cell. 2017 Sep 11;32(3):342-359.e10. doi: 10.1016/j.ccell.2017.08.010.

22.

Asymmetric dimethylarginine and symmetric dimethylarginine prospectively relates to carotid wall thickening in black men: the SABPA study.

Mels CMC, Schutte AE, Huisman HW, Smith W, Kruger R, van Rooyen JM, Schwedhelm E, Atzler D, Böger RH, Malan NT, Malan L.

Amino Acids. 2017 Nov;49(11):1843-1853. doi: 10.1007/s00726-017-2483-5. Epub 2017 Aug 22.

PMID:
28831582
23.

Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction.

Xu X, Zhang P, Kwak D, Fassett J, Yue W, Atzler D, Hu X, Liu X, Wang H, Lu Z, Guo H, Schwedhelm E, Böger RH, Chen P, Chen Y.

Basic Res Cardiol. 2017 Aug 17;112(5):55. doi: 10.1007/s00395-017-0644-z.

24.

Markers of nitric oxide are associated with sepsis severity: an observational study.

Winkler MS, Kluge S, Holzmann M, Moritz E, Robbe L, Bauer A, Zahrte C, Priefler M, Schwedhelm E, Böger RH, Goetz AE, Nierhaus A, Zoellner C.

Crit Care. 2017 Jul 15;21(1):189. doi: 10.1186/s13054-017-1782-2.

25.

AkrinorTM, a Cafedrine/ Theodrenaline Mixture (20:1), Increases Force of Contraction of Human Atrial Myocardium But Does Not Constrict Internal Mammary Artery In Vitro.

Kloth B, Pecha S, Moritz E, Schneeberger Y, Söhren KD, Schwedhelm E, Reichenspurner H, Eschenhagen T, Böger RH, Christ T, Stehr SN.

Front Pharmacol. 2017 May 23;8:272. doi: 10.3389/fphar.2017.00272. eCollection 2017.

26.

Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults.

Lüneburg N, Siques P, Brito J, De La Cruz JJ, León-Velarde F, Hannemann J, Ibanez C, Böger RH.

High Alt Med Biol. 2017 Sep;18(3):226-233. doi: 10.1089/ham.2016.0123. Epub 2017 Apr 28.

27.

Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease.

Zewinger S, Kleber ME, Rohrer L, Lehmann M, Triem S, Jennings RT, Petrakis I, Dressel A, Lepper PM, Scharnagl H, Ritsch A, Thorand B, Heier M, Meisinger C, de Las Heras Gala T, Koenig W, Wagenpfeil S, Schwedhelm E, Böger RH, Laufs U, von Eckardstein A, Landmesser U, Lüscher TF, Fliser D, März W, Meinitzer A, Speer T.

Eur Heart J. 2017 May 21;38(20):1597-1607. doi: 10.1093/eurheartj/ehx118.

PMID:
28379378
28.

Data on subgroup specific baseline characteristics and serum sphingosine-1-phosphate concentrations in the Study of Health in Pomerania.

Moritz E, Wegner D, Groß S, Bahls M, Dörr M, Felix SB, Ittermann T, Oswald S, Nauck M, Friedrich N, Böger RH, Daum G, Schwedhelm E, Rauch BH.

Data Brief. 2017 Mar 11;12:46-50. doi: 10.1016/j.dib.2017.03.019. eCollection 2017 Jun.

29.

Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania.

Moritz E, Wegner D, Groß S, Bahls M, Dörr M, Felix SB, Ittermann T, Oswald S, Nauck M, Friedrich N, Böger RH, Daum G, Schwedhelm E, Rauch BH.

Clin Chim Acta. 2017 May;468:25-31. doi: 10.1016/j.cca.2017.01.029. Epub 2017 Jan 31.

PMID:
28159438
30.

Acute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension.

Harbaum L, Renk E, Yousef S, Glatzel A, Lüneburg N, Hennigs JK, Oqueka T, Baumann HJ, Atanackovic D, Grünig E, Böger RH, Bokemeyer C, Klose H.

BMC Pulm Med. 2016 Nov 11;16(1):145.

31.

Higher serum asymmetric dimethylarginine is related to higher risk of heart failure in the EPIC-Potsdam study.

Wirth J, Atzler D, di Giuseppe R, Cordts K, Menzel J, Böger RH, Boeing H, Weikert C, Schwedhelm E.

Amino Acids. 2017 Jan;49(1):173-182. doi: 10.1007/s00726-016-2348-3. Epub 2016 Oct 28.

PMID:
27796501
32.

Short-term esmolol attenuates remodeling of the thoracic aorta in hypertensive rats by decreasing concentrations of ADMA down-regulated by oxidative stress.

Quintana-Villamandos B, González MC, Delgado-Martos MJ, Condezo-Hoyos L, Böger RH, Lüneburg N, Pazó-Sayós L, Gutiérrez-Arzapalo PY, Delgado-Baeza E.

Eur J Pharmacol. 2016 Nov 15;791:502-509. doi: 10.1016/j.ejphar.2016.09.020. Epub 2016 Sep 14.

PMID:
27639298
33.

Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.

Zhang W, Jernerén F, Lehne BC, Chen MH, Luben RN, Johnston C, Elshorbagy A, Eppinga RN, Scott WR, Adeyeye E, Scott J, Böger RH, Khaw KT, van der Harst P, Wareham NJ, Vasan RS, Chambers JC, Refsum H, Kooner JS.

Thromb Haemost. 2016 Nov 30;116(6):1041-1049. Epub 2016 Sep 22.

34.

Oral supplementation with L-homoarginine in young volunteers.

Atzler D, Schönhoff M, Cordts K, Ortland I, Hoppe J, Hummel FC, Gerloff C, Jaehde U, Jagodzinski A, Böger RH, Choe CU, Schwedhelm E.

Br J Clin Pharmacol. 2016 Dec;82(6):1477-1485. doi: 10.1111/bcp.13068. Epub 2016 Sep 20.

35.

The fission yeast MTREC and EJC orthologs ensure the maturation of meiotic transcripts during meiosis.

Marayati BF, Hoskins V, Boger RW, Tucker JF, Fishman ES, Bray AS, Zhang K.

RNA. 2016 Sep;22(9):1349-59. doi: 10.1261/rna.055608.115. Epub 2016 Jun 30.

36.

Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension?

Lüneburg N, Siques P, Brito J, Arriaza K, Pena E, Klose H, Leon-Velarde F, Böger RH.

Pulm Med. 2016;2016:6578578. doi: 10.1155/2016/6578578. Epub 2016 May 30.

37.

Asymmetric dimethylarginine, related arginine derivatives, and incident atrial fibrillation.

Schnabel RB, Maas R, Wang N, Yin X, Larson MG, Levy D, Ellinor PT, Lubitz SA, McManus DD, Magnani JW, Atzler D, Böger RH, Schwedhelm E, Vasan RS, Benjamin EJ.

Am Heart J. 2016 Jun;176:100-6. doi: 10.1016/j.ahj.2016.03.007. Epub 2016 Mar 17.

38.

Early regression of coronary artery remodeling with esmolol and DDAH/ADMA pathway in hypertensive rats.

Quintana-Villamandos B, Arnalich-Montiel A, Arribas S, Lüneburg N, Böger RH, Delgado-Martos MJ, Fernández-Criado C, Delgado-Baeza E, González MC.

Hypertens Res. 2016 Oct;39(10):692-700. doi: 10.1038/hr.2016.57. Epub 2016 Jun 2.

PMID:
27250567
39.

Homoarginine predicts mortality in treatment-naive patients with pulmonary arterial hypertension.

Atzler D, Cracowski JL, Cordts K, Böger RH, Humbert M, Schwedhelm E.

Int J Cardiol. 2016 Aug 15;217:12-5. doi: 10.1016/j.ijcard.2016.04.161. Epub 2016 May 2. No abstract available.

PMID:
27174592
40.

Low Homoarginine Levels in the Prognosis of Patients With Acute Chest Pain.

Atzler D, Baum C, Ojeda F, Keller T, Cordts K, Schnabel RB, Choe CU, Lackner KJ, Münzel T, Böger RH, Blankenberg S, Schwedhelm E, Zeller T.

J Am Heart Assoc. 2016 Apr 13;5(4):e002565. doi: 10.1161/JAHA.115.002565.

41.

The relationship of nitric oxide synthesis capacity, oxidative stress, and albumin-to-creatinine ratio in black and white men: the SABPA study.

Mels CM, Huisman HW, Smith W, Schutte R, Schwedhelm E, Atzler D, Böger RH, Ware LJ, Schutte AE.

Age (Dordr). 2016 Feb;38(1):9. doi: 10.1007/s11357-016-9873-6. Epub 2016 Jan 14.

42.

L-Arginine Derivatives Are Associated with the Hyperthyroid State in the General Population.

Ittermann T, Bahls M, Atzler D, Friedrich N, Schwedhelm E, Böger RH, Felix SB, Völzke H, Dörr M.

Thyroid. 2016 Feb;26(2):212-8. doi: 10.1089/thy.2015.0385. Epub 2015 Dec 28.

PMID:
26650143
43.

ADMA and arginine derivatives in relation to non-invasive vascular function in the general population.

Baum C, Johannsen SS, Zeller T, Atzler D, Ojeda FM, Wild PS, Sinning CR, Lackner KJ, Gori T, Schwedhelm E, Böger RH, Blankenberg S, Münzel T, Schnabel RB; Gutenberg Health Study investigators.

Atherosclerosis. 2016 Jan;244:149-56. doi: 10.1016/j.atherosclerosis.2015.10.101. Epub 2015 Oct 30.

PMID:
26638011
44.

ADMA, subclinical changes and atrial fibrillation in the general population.

Ramuschkat M, Appelbaum S, Atzler D, Zeller T, Bauer C, Ojeda FM, Sinning CR, Hoffmann B, Lackner KJ, Böger RH, Wild PS, Münzel T, Blankenberg S, Schwedhelm E, Schnabel RB; Gutenberg Health Study Investigators.

Int J Cardiol. 2016 Jan 15;203:640-6. doi: 10.1016/j.ijcard.2015.05.102. Epub 2015 May 19.

PMID:
26580348
45.

Nitric oxide synthesis capacity, ambulatory blood pressure and end organ damage in a black and white population: the SABPA study.

Mels CMC, Loots I, Schwedhelm E, Atzler D, Böger RH, Schutte AE.

Amino Acids. 2016 Mar;48(3):801-810. doi: 10.1007/s00726-015-2128-5. Epub 2015 Nov 16.

PMID:
26573539
46.

Reference intervals of plasma homoarginine from the German Gutenberg Health Study.

Atzler D, Appelbaum S, Cordts K, Ojeda FM, Wild PS, Münzel T, Blankenberg S, Böger RH, Blettner M, Beutel ME, Pfeiffer N, Zeller T, Lackner KJ, Schwedhelm E.

Clin Chem Lab Med. 2016 Jul 1;54(7):1231-7. doi: 10.1515/cclm-2015-0785.

PMID:
26562034
47.

FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis.

Menghini R, Casagrande V, Cardellini M, Ballanti M, Davato F, Cardolini I, Stoehr R, Fabrizi M, Morelli M, Anemona L, Bernges I, Schwedhelm E, Ippoliti A, Mauriello A, Böger RH, Federici M.

Atherosclerosis. 2015 Sep;242(1):230-5. doi: 10.1016/j.atherosclerosis.2015.07.026. Epub 2015 Jul 16.

PMID:
26226438
48.

Measurement of homoarginine in human and mouse plasma by LC-MS/MS and ELISA: a comparison and a biological application.

Cordts K, Atzler D, Qaderi V, Sydow K, Böger RH, Choe CU, Schwedhelm E.

Amino Acids. 2015 Sep;47(9):2015-22. doi: 10.1007/s00726-015-2037-7. Epub 2015 Jul 10.

PMID:
26159673
49.

L-Arginine and SDMA Serum Concentrations Are Associated with Subclinical Atherosclerosis in the Study of Health in Pomerania (SHIP).

Bahls M, Friedrich N, Atzler D, Felix SB, Nauck MA, Böger RH, Völzke H, Schwedhelm E, Dörr M.

PLoS One. 2015 Jun 22;10(6):e0131293. doi: 10.1371/journal.pone.0131293. eCollection 2015.

50.

Homoarginine supplementation improves blood glucose in diet-induced obese mice.

Stockebrand M, Hornig S, Neu A, Atzler D, Cordts K, Böger RH, Isbrandt D, Schwedhelm E, Choe CU.

Amino Acids. 2015 Sep;47(9):1921-9. doi: 10.1007/s00726-015-2022-1. Epub 2015 Jun 16.

PMID:
26077714

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