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Items: 1 to 50 of 227

1.

Novel Rare Genetic Variants Associated with Airflow Obstruction in the General Population.

de Vries M, van der Plaat DA, Nedeljkovic I, van der Velde KJ, Amin N, van Duijn CM, Vonk JM, Boezen HM, van Diemen CC.

Am J Respir Crit Care Med. 2019 Oct 18. doi: 10.1164/rccm.201909-1868LE. [Epub ahead of print] No abstract available.

PMID:
31626564
2.

Treatment-related mortality in children with cancer: Prevalence and risk factors.

Loeffen EAH, Knops RRG, Boerhof J, Feijen EAML, Merks JHM, Reedijk AMJ, Lieverst JA, Pieters R, Boezen HM, Kremer LCM, Tissing WJE.

Eur J Cancer. 2019 Nov;121:113-122. doi: 10.1016/j.ejca.2019.08.008. Epub 2019 Sep 27.

3.

Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression.

van der Plaat DA, Vonk JM, Terzikhan N, de Jong K, de Vries M, La Bastide-van Gemert S, van Diemen CC, Lahousse L, Brusselle GG, Nedeljkovic I, Amin N; BIOS Consortium, Kromhout H, Vermeulen RCH, Postma DS, van Duijn CM, Boezen HM.

Hum Mol Genet. 2019 Apr 2. pii: ddz067. doi: 10.1093/hmg/ddz067. [Epub ahead of print]

4.

Epigenome-wide association study of lung function level and its change.

Imboden M, Wielscher M, Rezwan FI, Amaral AFS, Schaffner E, Jeong A, Beckmeyer-Borowko A, Harris SE, Starr JM, Deary IJ, Flexeder C, Waldenberger M, Peters A, Schulz H, Chen S, Sunny SK, Karmaus WJJ, Jiang Y, Erhart G, Kronenberg F, Arathimos R, Sharp GC, Henderson AJ, Fu Y, Piirilä P, Pietiläinen KH, Ollikainen M, Johansson A, Gyllensten U, de Vries M, van der Plaat DA, de Jong K, Boezen HM, Hall IP, Tobin MD, Jarvelin MR, Holloway JW, Jarvis D, Probst-Hensch NM.

Eur Respir J. 2019 Jul 4;54(1). pii: 1900457. doi: 10.1183/13993003.00457-2019. Print 2019 Jul.

5.

Pathway analysis of a genome-wide gene by air pollution interaction study in asthmatic children.

Ierodiakonou D, Coull BA, Zanobetti A, Postma DS, Boezen HM, Vonk JM, McKone EF, Schildcrout JS, Koppelman GH, Croteau-Chonka DC, Lumley T, Koutrakis P, Schwartz J, Gold DR, Weiss ST.

J Expo Sci Environ Epidemiol. 2019 Jun;29(4):539-547. doi: 10.1038/s41370-019-0136-3. Epub 2019 Apr 26.

PMID:
31028280
6.

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu CJ, Huang RC, van der Plaat DA, Wielscher M, Merid SK, Ullemar V, Rezwan FI, Lahti J, van Dongen J, Langie SAS, Richardson TG, Magnus MC, Nohr EA, Xu Z, Duijts L, Zhao S, Zhang W, Plusquin M, DeMeo DL, Solomon O, Heimovaara JH, Jima DD, Gao L, Bustamante M, Perron P, Wright RO, Hertz-Picciotto I, Zhang H, Karagas MR, Gehring U, Marsit CJ, Beilin LJ, Vonk JM, Jarvelin MR, Bergström A, Örtqvist AK, Ewart S, Villa PM, Moore SE, Willemsen G, Standaert ARL, Håberg SE, Sørensen TIA, Taylor JA, Räikkönen K, Yang IV, Kechris K, Nawrot TS, Silver MJ, Gong YY, Richiardi L, Kogevinas M, Litonjua AA, Eskenazi B, Huen K, Mbarek H, Maguire RL, Dwyer T, Vrijheid M, Bouchard L, Baccarelli AA, Croen LA, Karmaus W, Anderson D, de Vries M, Sebert S, Kere J, Karlsson R, Arshad SH, Hämäläinen E, Routledge MN, Boomsma DI, Feinberg AP, Newschaffer CJ, Govarts E, Moisse M, Fallin MD, Melén E, Prentice AM, Kajantie E, Almqvist C, Oken E, Dabelea D, Boezen HM, Melton PE, Wright RJ, Koppelman GH, Trevisi L, Hivert MF, Sunyer J, Munthe-Kaas MC, Murphy SK, Corpeleijn E, Wiemels J, Holland N, Herceg Z, Binder EB, Davey Smith G, Jaddoe VWV, Lie RT, Nystad W, London SJ, Lawlor DA, Relton CL, Snieder H, Felix JF.

Nat Commun. 2019 Apr 23;10(1):1893. doi: 10.1038/s41467-019-09671-3.

7.

Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.

Zhu Z, Wang X, Li X, Lin Y, Shen S, Liu CL, Hobbs BD, Hasegawa K, Liang L; International COPD Genetics Consortium, Boezen HM, Camargo CA Jr, Cho MH, Christiani DC.

Respir Res. 2019 Apr 2;20(1):64. doi: 10.1186/s12931-019-1036-8.

8.

Congenital anomalies in the offspring of occupationally exposed mothers: a systematic review and meta-analysis of studies using expert assessment for occupational exposures.

Spinder N, Prins JR, Bergman JEH, Smidt N, Kromhout H, Boezen HM, de Walle HEK.

Hum Reprod. 2019 May 1;34(5):903-919. doi: 10.1093/humrep/dez033.

9.

Early cerebral and intestinal oxygenation in the risk assessment of necrotizing enterocolitis in preterm infants.

Schat TE, van Zoonen AGJF, van der Laan ME, Mebius MJ, Bos AF, Hulzebos CV, Boezen HM, Hulscher JBF, Kooi EMW.

Early Hum Dev. 2019 Apr;131:75-80. doi: 10.1016/j.earlhumdev.2019.03.001. Epub 2019 Mar 11.

PMID:
30870625
10.

Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population.

van der Plaat DA, Vonk JM, Lahousse L, de Jong K, Faiz A, Nedeljkovic I, Amin N, van Diemen CC, Brusselle GG, Bossé Y, Brandsma CA, Hao K, Paré PD, van Duijn CM, Postma DS, Boezen HM.

BMC Pulm Med. 2019 Mar 7;19(1):58. doi: 10.1186/s12890-019-0811-0.

11.

Recurrence risk of preeclampsia in a linked population-based cohort: Effects of first pregnancy maximum diastolic blood pressure and gestational age.

Bernardes TP, Mol BW, Ravelli ACJ, van den Berg PP, Boezen HM, Groen H.

Pregnancy Hypertens. 2019 Jan;15:32-36. doi: 10.1016/j.preghy.2018.10.010. Epub 2018 Nov 2.

PMID:
30825924
12.

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.

Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li X, Morrow JD, Obeidat M, Wyss AB, Bakke P, Barr RG, Beaty TH, Belinsky SA, Brusselle GG, Crapo JD, de Jong K, DeMeo DL, Fingerlin TE, Gharib SA, Gulsvik A, Hall IP, Hokanson JE, Kim WJ, Lomas DA, London SJ, Meyers DA, O'Connor GT, Rennard SI, Schwartz DA, Sliwinski P, Sparrow D, Strachan DP, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk JM, Yim JJ, Zhou X, Bossé Y, Manichaikul A, Lahousse L, Silverman EK, Boezen HM, Wain LV, Tobin MD, Hobbs BD, Cho MH; SpiroMeta Consortium; International COPD Genetics Consortium.

Nat Genet. 2019 Mar;51(3):494-505. doi: 10.1038/s41588-018-0342-2. Epub 2019 Feb 25.

13.

Genome-wide interaction study of gene-by-occupational exposures on respiratory symptoms.

Zeng X, Vonk JM, van der Plaat DA, Faiz A, Paré PD, Joubert P, Nickle D, Brandsma CA, Kromhout H, Vermeulen R, Xu X, Huo X, de Jong K, Boezen HM.

Environ Int. 2019 Jan;122:263-269. doi: 10.1016/j.envint.2018.11.017. Epub 2018 Nov 16.

14.

Sex, smoking and body mass index: do they aid in uncovering the complex mechanisms behind airway hyperresponsiveness?

Teferra AA, Vonk JM, Boezen HM.

Expert Rev Respir Med. 2018 Dec;12(12):989-991. doi: 10.1080/17476348.2018.1541741. Epub 2018 Oct 31. No abstract available.

PMID:
30362836
15.

Antigen-specific active immunotherapy for ovarian cancer.

Paijens ST, Leffers N, Daemen T, Helfrich W, Boezen HM, Cohlen BJ, Melief CJ, de Bruyn M, Nijman HW.

Cochrane Database Syst Rev. 2018 Sep 10;9:CD007287. doi: 10.1002/14651858.CD007287.pub4. Review.

16.

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Wyss AB, Sofer T, Lee MK, Terzikhan N, Nguyen JN, Lahousse L, Latourelle JC, Smith AV, Bartz TM, Feitosa MF, Gao W, Ahluwalia TS, Tang W, Oldmeadow C, Duan Q, de Jong K, Wojczynski MK, Wang XQ, Noordam R, Hartwig FP, Jackson VE, Wang T, Obeidat M, Hobbs BD, Huan T, Gui H, Parker MM, Hu D, Mogil LS, Kichaev G, Jin J, Graff M, Harris TB, Kalhan R, Heckbert SR, Paternoster L, Burkart KM, Liu Y, Holliday EG, Wilson JG, Vonk JM, Sanders JL, Barr RG, de Mutsert R, Menezes AMB, Adams HHH, van den Berge M, Joehanes R, Levin AM, Liberto J, Launer LJ, Morrison AC, Sitlani CM, Celedón JC, Kritchevsky SB, Scott RJ, Christensen K, Rotter JI, Bonten TN, Wehrmeister FC, Bossé Y, Xiao S, Oh S, Franceschini N, Brody JA, Kaplan RC, Lohman K, McEvoy M, Province MA, Rosendaal FR, Taylor KD, Nickle DC, Williams LK, Burchard EG, Wheeler HE, Sin DD, Gudnason V, North KE, Fornage M, Psaty BM, Myers RH, O'Connor G, Hansen T, Laurie CC, Cassano PA, Sung J, Kim WJ, Attia JR, Lange L, Boezen HM, Thyagarajan B, Rich SS, Mook-Kanamori DO, Horta BL, Uitterlinden AG, Im HK, Cho MH, Brusselle GG, Gharib SA, Dupuis J, Manichaikul A, London SJ.

Nat Commun. 2018 Jul 30;9(1):2976. doi: 10.1038/s41467-018-05369-0.

17.

No association between DNA methylation and COPD in never and current smokers.

de Vries M, van der Plaat DA, Vonk JM, Boezen HM.

BMJ Open Respir Res. 2018 Jun 29;5(1):e000282. doi: 10.1136/bmjresp-2018-000282. eCollection 2018.

18.

Rates of asthma exacerbations and mortality and associated factors in Uganda: a 2-year prospective cohort study.

Kirenga BJ, de Jong C, Mugenyi L, Katagira W, Muhofa A, Kamya MR, Boezen HM, van der Molen T.

Thorax. 2018 Oct;73(10):983-985. doi: 10.1136/thoraxjnl-2017-211157. Epub 2018 May 11.

PMID:
29752346
19.

A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants.

Nedeljkovic I, Terzikhan N, Vonk JM, van der Plaat DA, Lahousse L, van Diemen CC, Hobbs BD, Qiao D, Cho MH, Brusselle GG, Postma DS, Boezen HM, van Duijn CM, Amin N.

Front Genet. 2018 Apr 19;9:133. doi: 10.3389/fgene.2018.00133. eCollection 2018.

20.

Promoting respiratory public health through epigenetics research: an ERS Environment Health Committee workshop report.

Melén E, Barouki R, Barry M, Boezen HM, Hoffmann B, Krauss-Etschmann S, Koppelman GH, Forsberg B.

Eur Respir J. 2018 Apr 4;51(4). pii: 1702410. doi: 10.1183/13993003.02410-2017. Print 2018 Apr. No abstract available.

21.

Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations.

Lamontagne M, Bérubé JC, Obeidat M, Cho MH, Hobbs BD, Sakornsakolpat P, de Jong K, Boezen HM; International COPD Genetics Consortium, Nickle D, Hao K, Timens W, van den Berge M, Joubert P, Laviolette M, Sin DD, Paré PD, Bossé Y.

Hum Mol Genet. 2018 May 15;27(10):1819-1829. doi: 10.1093/hmg/ddy091.

22.

Blood Eosinophil Count and Metabolic, Cardiac and Pulmonary Outcomes: A Mendelian Randomization Study.

Amini M, Vonk JM, Abbasi A, Prins BP, Bruinenberg M, Franke L, van der Harst P, Navis G, Koppelman GH, Wolffenbuttel BHR, Boezen HM, Snieder H, Chasman DI, Alizadeh BZ.

Twin Res Hum Genet. 2018 Apr;21(2):89-100. doi: 10.1017/thg.2018.6. Epub 2018 Mar 6.

PMID:
29506594
23.

Occupational exposure to pesticides is associated with differential DNA methylation.

van der Plaat DA, de Jong K, de Vries M, van Diemen CC, Nedeljković I, Amin N, Kromhout H; Biobank-based Integrative Omics Study Consortium, Vermeulen R, Postma DS, van Duijn CM, Boezen HM, Vonk JM.

Occup Environ Med. 2018 Jun;75(6):427-435. doi: 10.1136/oemed-2017-104787. Epub 2018 Feb 19.

24.

Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics.

Nedeljkovic I, Carnero-Montoro E, Lahousse L, van der Plaat DA, de Jong K, Vonk JM, van Diemen CC, Faiz A, van den Berge M, Obeidat M, Bossé Y, Nickle DC, Consortium B, Uitterlinden AG, van Meurs JJB, Stricker BCH, Brusselle GG, Postma DS, Boezen HM, van Duijn CM, Amin N.

Eur J Hum Genet. 2018 May;26(5):709-722. doi: 10.1038/s41431-017-0089-8. Epub 2018 Feb 8.

25.

Long-term Air Pollution Exposure, Genome-wide DNA Methylation and Lung Function in the LifeLines Cohort Study.

de F C Lichtenfels AJ, van der Plaat DA, de Jong K, van Diemen CC, Postma DS, Nedeljkovic I, van Duijn CM, Amin N, la Bastide-van Gemert S, de Vries M, Ward-Caviness CK, Wolf K, Waldenberger M, Peters A, Stolk RP, Brunekreef B, Boezen HM, Vonk JM.

Environ Health Perspect. 2018 Feb 6;126(2):027004. doi: 10.1289/EHP2045.

26.

COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression.

Nedeljkovic I, Lahousse L, Carnero-Montoro E, Faiz A, Vonk JM, de Jong K, van der Plaat DA, van Diemen CC, van den Berge M, Obeidat M, Bossé Y, Nickle DC, Consortium BIOS, Uitterlinden AG, van Meurs JBJ, Stricker BHC, Brusselle GG, Postma DS, Boezen HM, van Duijn CM, Amin N.

Hum Mol Genet. 2018 Jan 15;27(2):396-405. doi: 10.1093/hmg/ddx390.

27.

Prevalence of asthma-like symptoms with ageing.

Jarvis D, Newson R, Janson C, Corsico A, Heinrich J, Anto JM, Abramson MJ, Kirsten AM, Zock JP, Bono R, Demoly P, Leynaert B, Raherison C, Pin I, Gislason T, Jogi R, Schlunssen V, Svanes C, Watkins J, Weyler J, Pereira-Vega A, Urrutia I, Gullón JA, Forsberg B, Probst-Hensch N, Boezen HM, Martinez-Moratalla Rovira J, Accordini S, de Marco R, Burney P.

Thorax. 2018 Jan;73(1):37-48. doi: 10.1136/thoraxjnl-2016-209596. Epub 2017 Oct 3.

28.

Maternal occupational exposure and oral clefts in offspring.

Spinder N, Bergman JEH, Boezen HM, Vermeulen RCH, Kromhout H, de Walle HEK.

Environ Health. 2017 Aug 4;16(1):83. doi: 10.1186/s12940-017-0294-5.

29.

Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure.

de Jong K, Vonk JM, Imboden M, Lahousse L, Hofman A, Brusselle GG, Probst-Hensch NM, Postma DS, Boezen HM.

Respir Res. 2017 Jul 24;18(1):142. doi: 10.1186/s12931-017-0625-7.

30.

Decreased lung function with mediation of blood parameters linked to e-waste lead and cadmium exposure in preschool children.

Zeng X, Xu X, Boezen HM, Vonk JM, Wu W, Huo X.

Environ Pollut. 2017 Nov;230:838-848. doi: 10.1016/j.envpol.2017.07.014. Epub 2017 Jul 19.

PMID:
28734265
31.

Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice.

Pouwels SD, Faiz A, den Boef LE, Gras R, van den Berge M, Boezen HM, Korstanje R, Ten Hacken NHT, van Oosterhout AJM, Heijink IH, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L559-L580. doi: 10.1152/ajplung.00466.2016. Epub 2017 Jun 8.

32.

Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease.

Weidner J, Jarenbäck L, de Jong K, Vonk JM, van den Berge M, Brandsma CA, Boezen HM, Sin D, Bossé Y, Nickle D, Ankerst J, Bjermer L, Postma DS, Faiz A, Tufvesson E.

Respir Res. 2017 May 2;18(1):77. doi: 10.1186/s12931-017-0562-5.

33.

Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study.

Nolte IM, van der Most PJ, Alizadeh BZ, de Bakker PI, Boezen HM, Bruinenberg M, Franke L, van der Harst P, Navis G, Postma DS, Rots MG, Stolk RP, Swertz MA, Wolffenbuttel BH, Wijmenga C, Snieder H.

Eur J Hum Genet. 2017 Jun;25(7):877-885. doi: 10.1038/ejhg.2017.50. Epub 2017 Apr 12.

34.

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.

Smith D, Helgason H, Sulem P, Bjornsdottir US, Lim AC, Sveinbjornsson G, Hasegawa H, Brown M, Ketchem RR, Gavala M, Garrett L, Jonasdottir A, Jonasdottir A, Sigurdsson A, Magnusson OT, Eyjolfsson GI, Olafsson I, Onundarson PT, Sigurdardottir O, Gislason D, Gislason T, Ludviksson BR, Ludviksdottir D, Boezen HM, Heinzmann A, Krueger M, Porsbjerg C, Ahluwalia TS, Waage J, Backer V, Deichmann KA, Koppelman GH, Bønnelykke K, Bisgaard H, Masson G, Thorsteinsdottir U, Gudbjartsson DF, Johnston JA, Jonsdottir I, Stefansson K.

PLoS Genet. 2017 Mar 8;13(3):e1006659. doi: 10.1371/journal.pgen.1006659. eCollection 2017 Mar.

35.

Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium.

Vonk JM, Scholtens S, Postma DS, Moffatt MF, Jarvis D, Ramasamy A, Wjst M, Omenaas ER, Bouzigon E, Demenais F, Nadif R, Siroux V, Polonikov AV, Solodilova M, Ivanov VP, Curjuric I, Imboden M, Kumar A, Probst-Hensch N, Ogorodova LM, Puzyrev VP, Bragina EY, Freidin MB, Nolte IM, Farrall AM, Cookson WO, Strachan DP, Koppelman GH, Boezen HM.

PLoS One. 2017 Mar 2;12(3):e0172716. doi: 10.1371/journal.pone.0172716. eCollection 2017.

36.

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, Hokanson JE, Crapo JD, Castaldi PJ, Chase RP, Bartz TM, Heckbert SR, Psaty BM, Gharib SA, Zanen P, Lammers JW, Oudkerk M, Groen HJ, Locantore N, Tal-Singer R, Rennard SI, Vestbo J, Timens W, Paré PD, Latourelle JC, Dupuis J, O'Connor GT, Wilk JB, Kim WJ, Lee MK, Oh YM, Vonk JM, de Koning HJ, Leng S, Belinsky SA, Tesfaigzi Y, Manichaikul A, Wang XQ, Rich SS, Barr RG, Sparrow D, Litonjua AA, Bakke P, Gulsvik A, Lahousse L, Brusselle GG, Stricker BH, Uitterlinden AG, Ampleford EJ, Bleecker ER, Woodruff PG, Meyers DA, Qiao D, Lomas DA, Yim JJ, Kim DK, Hawrylkiewicz I, Sliwinski P, Hardin M, Fingerlin TE, Schwartz DA, Postma DS, MacNee W, Tobin MD, Silverman EK, Boezen HM, Cho MH; COPDGene Investigators; ECLIPSE Investigators; LifeLines Investigators; SPIROMICS Research Group; International COPD Genetics Network Investigators; UK BiLEVE Investigators; International COPD Genetics Consortium.

Nat Genet. 2017 Mar;49(3):426-432. doi: 10.1038/ng.3752. Epub 2017 Feb 6.

37.

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

Aschard H, Tobin MD, Hancock DB, Skurnik D, Sood A, James A, Vernon Smith A, Manichaikul AW, Campbell A, Prins BP, Hayward C, Loth DW, Porteous DJ, Strachan DP, Zeggini E, O'Connor GT, Brusselle GG, Boezen HM, Schulz H, Deary IJ, Hall IP, Rudan I, Kaprio J, Wilson JF, Wilk JB, Huffman JE, Hua Zhao J, de Jong K, Lyytikäinen LP, Wain LV, Jarvelin MR, Kähönen M, Fornage M, Polasek O, Cassano PA, Barr RG, Rawal R, Harris SE, Gharib SA, Enroth S, Heckbert SR, Lehtimäki T, Gyllensten U; Understanding Society Scientific Group, Jackson VE, Gudnason V, Tang W, Dupuis J, Soler Artigas M, Joshi AD, London SJ, Kraft P.

Int J Epidemiol. 2017 Jun 1;46(3):894-904. doi: 10.1093/ije/dyw318.

38.

No convincing association between genetic markers and respiratory symptoms: results of a GWA study.

Zeng X, Vonk JM, de Jong K, Xu X, Huo X, Boezen HM.

Respir Res. 2017 Jan 10;18(1):11. doi: 10.1186/s12931-016-0495-4.

39.

Eosinophil Count Is a Common Factor for Complex Metabolic and Pulmonary Traits and Diseases: The LifeLines Cohort Study.

Amini M, Bashirova D, Prins BP, Corpeleijn E; LifeLines Cohort Study, Bruinenberg M, Franke L, Harst PV, Navis G, Wolffenbuttel BH, Stolk RP, Wijmenga C, Postma DS, Koppelman GH, Boezen HM, Vonk J, Snieder H, Alizadeh BZ.

PLoS One. 2016 Dec 15;11(12):e0168480. doi: 10.1371/journal.pone.0168480. eCollection 2016.

40.

The Well-Known Gene HHIP and Novel Gene MECR Are Implicated in Small Airway Obstruction.

van der Plaat DA, de Jong K, Lahousse L, Faiz A, Vonk JM, van Diemen CC, Nedeljkovic I, Amin N, Obeidat M, van Duijn CM, Boezen HM, Postma DS.

Am J Respir Crit Care Med. 2016 Nov 15;194(10):1299-1302. No abstract available.

PMID:
27845578
41.

Novel Genetic Susceptibility Loci for FEV1 in the Context of Occupational Exposure in Never-Smokers.

de Jong K, Vonk JM, Faiz A, van der Plaat DA, Timens W, Bossé Y, Kromhout H, Nedeljkovic I, Postma DS, Boezen HM.

Am J Respir Crit Care Med. 2016 Sep 15;194(6):769-72. doi: 10.1164/rccm.201603-0646LE. No abstract available.

PMID:
27628080
42.

Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A.

van der Plaat DA, de Jong K, Lahousse L, Faiz A, Vonk JM, van Diemen CC, Nedeljkovic I, Amin N, Brusselle GG, Hofman A, Brandsma CA, Bossé Y, Sin DD, Nickle DC, van Duijn CM, Postma DS, Boezen HM.

J Allergy Clin Immunol. 2017 Feb;139(2):533-540. doi: 10.1016/j.jaci.2016.06.062. Epub 2016 Sep 6.

PMID:
27612410
43.

Air pollution exposure is associated with restrictive ventilatory patterns.

de Jong K, Vonk JM, Zijlema WL, Stolk RP, van der Plaat DA, Hoek G, Brunekreef B, Postma DS, Boezen HM; LifeLines Cohort Study Group.

Eur Respir J. 2016 Oct;48(4):1221-1224. doi: 10.1183/13993003.00556-2016. Epub 2016 Aug 4. No abstract available.

44.

Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.

Nieuwenhuis MA, Siedlinski M, van den Berge M, Granell R, Li X, Niens M, van der Vlies P, Altmüller J, Nürnberg P, Kerkhof M, van Schayck OC, Riemersma RA, van der Molen T, de Monchy JG, Bossé Y, Sandford A, Bruijnzeel-Koomen CA, Gerth van Wijk R, Ten Hacken NH, Timens W, Boezen HM, Henderson J, Kabesch M, Vonk JM, Postma DS, Koppelman GH.

Allergy. 2016 Dec;71(12):1712-1720. doi: 10.1111/all.12990. Epub 2016 Aug 22.

45.

Advanced glycation endproducts and their receptor in different body compartments in COPD.

Hoonhorst SJ, Lo Tam Loi AT, Pouwels SD, Faiz A, Telenga ED, van den Berge M, Koenderman L, Lammers JW, Boezen HM, van Oosterhout AJ, Lodewijk ME, Timens W, Postma DS, Ten Hacken NH.

Respir Res. 2016 Apr 26;17:46. doi: 10.1186/s12931-016-0363-2.

46.

Lifetime Smoking History and Cause-Specific Mortality in a Cohort Study with 43 Years of Follow-Up.

Taghizadeh N, Vonk JM, Boezen HM.

PLoS One. 2016 Apr 7;11(4):e0153310. doi: 10.1371/journal.pone.0153310. eCollection 2016.

47.

Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.

Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner VD, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M.

J Allergy Clin Immunol. 2016 Aug;138(2):421-31. doi: 10.1016/j.jaci.2015.12.1305. Epub 2016 Feb 20.

PMID:
26906082
48.

Very early discharge versus early discharge versus non-early discharge in children with cancer and febrile neutropenia.

Loeffen EA, Te Poele EM, Tissing WJ, Boezen HM, de Bont ES.

Cochrane Database Syst Rev. 2016 Feb 22;2:CD008382. doi: 10.1002/14651858.CD008382.pub2. Review.

PMID:
26899263
49.

Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma.

Ierodiakonou D, Portelli MA, Postma DS, Koppelman GH, Gerritsen J, Ten Hacken NH, Timens W, Boezen HM, Vonk JM, Sayers I.

Eur Respir J. 2016 May;47(5):1568-71. doi: 10.1183/13993003.01571-2015. Epub 2016 Feb 11. No abstract available.

50.

Children with health impairments by heavy metals in an e-waste recycling area.

Zeng X, Xu X, Boezen HM, Huo X.

Chemosphere. 2016 Apr;148:408-15. doi: 10.1016/j.chemosphere.2015.10.078. Epub 2016 Jan 30. Review.

PMID:
26829309

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