Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 226


Disruption of the Microglial ADP Receptor P2Y13 Enhances Adult Hippocampal Neurogenesis.

Stefani J, Tschesnokowa O, Parrilla M, Robaye B, Boeynaems JM, Acker-Palmer A, Zimmermann H, Gampe K.

Front Cell Neurosci. 2018 May 17;12:134. doi: 10.3389/fncel.2018.00134. eCollection 2018.


P2Y6 Receptor Activation Promotes Inflammation and Tissue Remodeling in Pulmonary Fibrosis.

Müller T, Fay S, Vieira RP, Karmouty-Quintana H, Cicko S, Ayata CK, Zissel G, Goldmann T, Lungarella G, Ferrari D, Di Virgilio F, Robaye B, Boeynaems JM, Lazarowski ER, Blackburn MR, Idzko M.

Front Immunol. 2017 Aug 22;8:1028. doi: 10.3389/fimmu.2017.01028. eCollection 2017.


The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease.

Müller T, Fay S, Vieira RP, Karmouty-Quintana H, Cicko S, Ayata K, Zissel G, Goldmann T, Lungarella G, Ferrari D, Di Virgilio F, Robaye B, Boeynaems JM, Blackburn MR, Idzko M.

Oncotarget. 2017 May 30;8(22):35962-35972. doi: 10.18632/oncotarget.16414.


Mouse P2Y4 Nucleotide Receptor Is a Negative Regulator of Cardiac Adipose-Derived Stem Cell Differentiation and Cardiac Fat Formation.

Lemaire A, Vanorlé M, Horckmans M, di Pietrantonio L, Clouet S, Robaye B, Boeynaems JM, Communi D.

Stem Cells Dev. 2017 Mar 1;26(5):363-373. doi: 10.1089/scd.2016.0166. Epub 2016 Dec 23.


Central Role of P2Y6 UDP Receptor in Arteriolar Myogenic Tone.

Kauffenstein G, Tamareille S, Prunier F, Roy C, Ayer A, Toutain B, Billaud M, Isakson BE, Grimaud L, Loufrani L, Rousseau P, Abraham P, Procaccio V, Monyer H, de Wit C, Boeynaems JM, Robaye B, Kwak BR, Henrion D.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1598-606. doi: 10.1161/ATVBAHA.116.307739. Epub 2016 Jun 2.


Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy.

Clouet S, Di Pietrantonio L, Daskalopoulos EP, Esfahani H, Horckmans M, Vanorlé M, Lemaire A, Balligand JL, Beauloye C, Boeynaems JM, Communi D.

J Biol Chem. 2016 Jul 22;291(30):15841-52. doi: 10.1074/jbc.M115.684118. Epub 2016 May 26.


New insights on pyrimidine signalling within the arterial vasculature - Different roles for P2Y2 and P2Y6 receptors in large and small coronary arteries of the mouse.

Haanes KA, Spray S, Syberg S, Jørgensen NR, Robaye B, Boeynaems JM, Edvinsson L.

J Mol Cell Cardiol. 2016 Apr;93:1-11. doi: 10.1016/j.yjmcc.2016.01.025. Epub 2016 Jan 28.


Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II-induced hypertension.

Nishimura A, Sunggip C, Tozaki-Saitoh H, Shimauchi T, Numaga-Tomita T, Hirano K, Ide T, Boeynaems JM, Kurose H, Tsuda M, Robaye B, Inoue K, Nishida M.

Sci Signal. 2016 Jan 19;9(411):ra7. doi: 10.1126/scisignal.aac9187.


Increased atherosclerosis in P2Y13/apolipoprotein E double-knockout mice: contribution of P2Y13 to reverse cholesterol transport.

Lichtenstein L, Serhan N, Espinosa-Delgado S, Fabre A, Annema W, Tietge UJ, Robaye B, Boeynaems JM, Laffargue M, Perret B, Martinez LO.

Cardiovasc Res. 2015 May 1;106(2):314-23. doi: 10.1093/cvr/cvv109. Epub 2015 Mar 13.


P2Y2R deficiency attenuates experimental autoimmune uveitis development.

Relvas LJ, Makhoul M, Dewispelaere R, Caspers L, Communi D, Boeynaems JM, Robaye B, Bruyns C, Willermain F.

PLoS One. 2015 Feb 18;10(2):e0116518. doi: 10.1371/journal.pone.0116518. eCollection 2015.


Loss of mouse P2Y4 nucleotide receptor protects against myocardial infarction through endothelin-1 downregulation.

Horckmans M, Esfahani H, Beauloye C, Clouet S, di Pietrantonio L, Robaye B, Balligand JL, Boeynaems JM, Dessy C, Communi D.

J Immunol. 2015 Feb 15;194(4):1874-81. doi: 10.4049/jimmunol.1401364. Epub 2015 Jan 16.


Enhancement of glucose uptake in mouse skeletal muscle cells and adipocytes by P2Y6 receptor agonists.

Balasubramanian R, Robaye B, Boeynaems JM, Jacobson KA.

PLoS One. 2014 Dec 30;9(12):e116203. doi: 10.1371/journal.pone.0116203. eCollection 2014.


Purinergic signalling and immune cells.

Burnstock G, Boeynaems JM.

Purinergic Signal. 2014 Dec;10(4):529-64. doi: 10.1007/s11302-014-9427-2. Epub 2014 Oct 29. Review.


The enteric nervous system of P2Y13 receptor null mice is resistant against high-fat-diet- and palmitic-acid-induced neuronal loss.

Voss U, Turesson MF, Robaye B, Boeynaems JM, Olde B, Erlinge D, Ekblad E.

Purinergic Signal. 2014 Sep;10(3):455-64. doi: 10.1007/s11302-014-9408-5. Epub 2014 Feb 9.


The P2Y13 receptor regulates phosphate metabolism and FGF-23 secretion with effects on skeletal development.

Wang N, Robaye B, Gossiel F, Boeynaems JM, Gartland A.

FASEB J. 2014 May;28(5):2249-59. doi: 10.1096/fj.13-243626. Epub 2014 Jan 31.


Lack of P2Y13 in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport.

Lichtenstein L, Serhan N, Annema W, Combes G, Robaye B, Boeynaems JM, Perret B, Tietge UJF, Laffargue M, Martinez LO.

Nutr Metab (Lond). 2013 Nov 6;10(1):67. doi: 10.1186/1743-7075-10-67.


A European approach to clinical investigator training.

Boeynaems JM, Canivet C, Chan A, Clarke MJ, Cornu C, Daemen E, Demotes J, Nys KD, Hirst B, Hundt F, Kassai B, Kerpel-Fronius S, Kiessig L, Klech H, Kraehenbuhl JP, Lafolie P, Lucht M, Niese D, Pauli-Magnus C, Peters B, Schaltenbrand R, Stockis A, Stykova M, Verheus N, Klingmann I.

Front Pharmacol. 2013 Sep 9;4:112. doi: 10.3389/fphar.2013.00112. Review.


Role of the P2Y13 receptor in the differentiation of bone marrow stromal cells into osteoblasts and adipocytes.

Biver G, Wang N, Gartland A, Orriss I, Arnett TR, Boeynaems JM, Robaye B.

Stem Cells. 2013 Dec;31(12):2747-58. doi: 10.1002/stem.1411.


Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition.

Guenther F, Herr N, Mauler M, Witsch T, Roming F, Hein L, Boeynaems JM, Robaye B, Idzko M, Bode C, Von Zur Muhlen C, Duerschmied D.

J Thromb Haemost. 2013 Jun;11(6):1154-62. doi: 10.1111/jth.12206.


Reply to: 'the discovery of a new class of synaptic transmitters in smooth muscle fifty years ago and amelioration of coronary artery thrombosis'.

Abbracchio MP, Boeynaems JM, Cattaneo M, Di Virgilio F, Illes P, Inoue K, Jacobson KA, Teresa Miras-Portugal M, Ralevic V, Robson SC, Verkhratsky A, Zimmermann H.

Acta Physiol (Oxf). 2013 Jun;208(2):139-40. doi: 10.1111/apha.12101. Epub 2013 Apr 17. No abstract available.


The P2Y13 receptor regulates extracellular ATP metabolism and the osteogenic response to mechanical loading.

Wang N, Rumney RM, Yang L, Robaye B, Boeynaems JM, Skerry TM, Gartland A.

J Bone Miner Res. 2013 Jun;28(6):1446-56. doi: 10.1002/jbmr.1877.


Protective role of P2Y2 receptor against lung infection induced by pneumonia virus of mice.

Vanderstocken G, Van de Paar E, Robaye B, di Pietrantonio L, Bondue B, Boeynaems JM, Desmecht D, Communi D.

PLoS One. 2012;7(11):e50385. doi: 10.1371/journal.pone.0050385. Epub 2012 Nov 21.


Purinergic P2Y₂ receptors promote neutrophil infiltration and hepatocyte death in mice with acute liver injury.

Ayata CK, Ganal SC, Hockenjos B, Willim K, Vieira RP, Grimm M, Robaye B, Boeynaems JM, Di Virgilio F, Pellegatti P, Diefenbach A, Idzko M, Hasselblatt P.

Gastroenterology. 2012 Dec;143(6):1620-1629.e4. doi: 10.1053/j.gastro.2012.08.049. Epub 2012 Sep 11.


Gene deletion of P2Y4 receptor lowers exercise capacity and reduces myocardial hypertrophy with swimming exercise.

Horckmans M, Léon-Gómez E, Robaye B, Balligand JL, Boeynaems JM, Dessy C, Communi D.

Am J Physiol Heart Circ Physiol. 2012 Oct 1;303(7):H835-43. doi: 10.1152/ajpheart.00256.2012. Epub 2012 Aug 3.


Involvement of protein kinase D in uridine diphosphate-induced microglial macropinocytosis and phagocytosis.

Uesugi A, Kataoka A, Tozaki-Saitoh H, Koga Y, Tsuda M, Robaye B, Boeynaems JM, Inoue K.

Glia. 2012 Jul;60(7):1094-105. doi: 10.1002/glia.22337. Epub 2012 Apr 4.


P2Y(4) nucleotide receptor: a novel actor in post-natal cardiac development.

Horckmans M, Robaye B, Léon-Gόmez E, Lantz N, Unger P, Dol-Gleizes F, Clouet S, Cammarata D, Schaeffer P, Savi P, Gachet C, Balligand JL, Dessy C, Boeynaems JM, Communi D.

Angiogenesis. 2012 Sep;15(3):349-60. doi: 10.1007/s10456-012-9265-1. Epub 2012 Mar 22.


Reduced bone turnover in mice lacking the P2Y13 receptor of ADP.

Wang N, Robaye B, Agrawal A, Skerry TM, Boeynaems JM, Gartland A.

Mol Endocrinol. 2012 Jan;26(1):142-52. doi: 10.1210/me.2011-1083. Epub 2011 Nov 22.


The P2Y(6) receptor stimulates bone resorption by osteoclasts.

Orriss IR, Wang N, Burnstock G, Arnett TR, Gartland A, Robaye B, Boeynaems JM.

Endocrinology. 2011 Oct;152(10):3706-16. doi: 10.1210/en.2011-1073. Epub 2011 Aug 9.


Bone phenotypes of P2 receptor knockout mice.

Orriss I, Syberg S, Wang N, Robaye B, Gartland A, Jorgensen N, Arnett T, Boeynaems JM.

Front Biosci (Schol Ed). 2011 Jun 1;3:1038-46.


Purinergic receptor type 6 contributes to airway inflammation and remodeling in experimental allergic airway inflammation.

Vieira RP, Müller T, Grimm M, von Gernler V, Vetter B, Dürk T, Cicko S, Ayata CK, Sorichter S, Robaye B, Zeiser R, Ferrari D, Kirschbaum A, Zissel G, Virchow JC, Boeynaems JM, Idzko M.

Am J Respir Crit Care Med. 2011 Jul 15;184(2):215-23. doi: 10.1164/rccm.201011-1762OC. Epub 2011 Apr 21.


Erratum to: The unexpected roles of extracellular ADP and P2Y(13) receptor in reverse cholesterol transport.

Boeynaems JM, Sirtori CR.

Purinergic Signal. 2011 Mar;7(1):165. doi: 10.1007/s11302-011-9219-x. No abstract available.


European meeting "P2 receptors: new targets for the treatment of osteoporosis".

Jørgensen NR, Boeynaems JM, Di Virgilio F.

Purinergic Signal. 2011 Jun;7(2):275-6. doi: 10.1007/s11302-011-9223-1. Epub 2011 Feb 18. No abstract available.


The unexpected roles of extracellular ADP and P2Y(13) receptor in reverse cholesterol transport.

Boeynaems JM, Sirtori CR.

Purinergic Signal. 2010 Dec;6(4):361-3. doi: 10.1007/s11302-010-9211-x. Epub 2010 Dec 14. No abstract available.


Selective induction of endothelial P2Y6 nucleotide receptor promotes vascular inflammation.

Riegel AK, Faigle M, Zug S, Rosenberger P, Robaye B, Boeynaems JM, Idzko M, Eltzschig HK.

Blood. 2011 Feb 24;117(8):2548-55. doi: 10.1182/blood-2010-10-313957. Epub 2010 Dec 20.


Role of the P2Y12 receptor in the modulation of murine dendritic cell function by ADP.

Ben Addi A, Cammarata D, Conley PB, Boeynaems JM, Robaye B.

J Immunol. 2010 Nov 15;185(10):5900-6. doi: 10.4049/jimmunol.0901799. Epub 2010 Oct 15.


The purinergic receptor P2Y2 receptor mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation.

Müller T, Robaye B, Vieira RP, Ferrari D, Grimm M, Jakob T, Martin SF, Di Virgilio F, Boeynaems JM, Virchow JC, Idzko M.

Allergy. 2010 Dec;65(12):1545-53. doi: 10.1111/j.1398-9995.2010.02426.x. Epub 2010 Sep 29.


P2Y13 receptor is critical for reverse cholesterol transport.

Fabre AC, Malaval C, Ben Addi A, Verdier C, Pons V, Serhan N, Lichtenstein L, Combes G, Huby T, Briand F, Collet X, Nijstad N, Tietge UJ, Robaye B, Perret B, Boeynaems JM, Martinez LO.

Hepatology. 2010 Oct;52(4):1477-83. doi: 10.1002/hep.23897.


P2Y2 receptor regulates VCAM-1 membrane and soluble forms and eosinophil accumulation during lung inflammation.

Vanderstocken G, Bondue B, Horckmans M, Di Pietrantonio L, Robaye B, Boeynaems JM, Communi D.

J Immunol. 2010 Sep 15;185(6):3702-7. doi: 10.4049/jimmunol.0903908. Epub 2010 Aug 18.


ATP confers tumorigenic properties to dendritic cells by inducing amphiregulin secretion.

Bles N, Di Pietrantonio L, Boeynaems JM, Communi D.

Blood. 2010 Oct 28;116(17):3219-26. doi: 10.1182/blood-2010-01-265611. Epub 2010 Jul 22.


P2Y nucleotide receptors: promise of therapeutic applications.

Jacobson KA, Boeynaems JM.

Drug Discov Today. 2010 Jul;15(13-14):570-8. doi: 10.1016/j.drudis.2010.05.011. Epub 2010 Jun 2. Review.


Purinergic receptor inhibition prevents the development of smoke-induced lung injury and emphysema.

Cicko S, Lucattelli M, Müller T, Lommatzsch M, De Cunto G, Cardini S, Sundas W, Grimm M, Zeiser R, Dürk T, Zissel G, Boeynaems JM, Sorichter S, Ferrari D, Di Virgilio F, Virchow JC, Lungarella G, Idzko M.

J Immunol. 2010 Jul 1;185(1):688-97. doi: 10.4049/jimmunol.0904042. Epub 2010 Jun 2.


Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology.

Leroy K, Ando K, Héraud C, Yilmaz Z, Authelet M, Boeynaems JM, Buée L, De Decker R, Brion JP.

J Alzheimers Dis. 2010;19(2):705-19. doi: 10.3233/JAD-2010-1276.


[Reimbursement and rational prescription of laboratory tests].

Boeynaems JM.

Rev Med Brux. 2009 Sep;30(4):446-9. French.


NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleukin-8 from human monocyte-derived dendritic cells.

Meis S, Hamacher A, Hongwiset D, Marzian C, Wiese M, Eckstein N, Royer HD, Communi D, Boeynaems JM, Hausmann R, Schmalzing G, Kassack MU.

J Pharmacol Exp Ther. 2010 Jan;332(1):238-47. doi: 10.1124/jpet.109.157750. Epub 2009 Oct 8.


Extracellular nucleotides as negative modulators of immunity.

Di Virgilio F, Boeynaems JM, Robson SC.

Curr Opin Pharmacol. 2009 Aug;9(4):507-13. doi: 10.1016/j.coph.2009.06.021. Epub 2009 Jul 21. Review.


Extracellular nucleotides and interleukin-8 production by ARPE cells: potential role of danger signals in blood-retinal barrier activation.

Relvas LJ, Bouffioux C, Marcet B, Communi D, Makhoul M, Horckmans M, Blero D, Bruyns C, Caspers L, Boeynaems JM, Willermain F.

Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1241-6. doi: 10.1167/iovs.08-1902. Epub 2008 Nov 21.


Determination of urinary iodine by inductively coupled plasma mass spectrometry.

Macours P, Aubry JC, Hauquier B, Boeynaems JM, Goldman S, Moreno-Reyes R.

J Trace Elem Med Biol. 2008;22(2):162-5. doi: 10.1016/j.jtemb.2008.02.003. Epub 2008 Jun 5.


Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A(2B) receptor.

Ben Addi A, Lefort A, Hua X, Libert F, Communi D, Ledent C, Macours P, Tilley SL, Boeynaems JM, Robaye B.

Eur J Immunol. 2008 Jun;38(6):1610-20. doi: 10.1002/eji.200737781.


Molecular mechanisms of extracellular adenine nucleotides-mediated inhibition of human Cd4(+) T lymphocytes activation.

Duhant X, Suarez Gonzalez N, Schandené L, Goldman M, Communi D, Boeynaems JM.

Purinergic Signal. 2005 Dec;1(4):377-81. doi: 10.1007/s11302-005-8077-9. Epub 2005 Dec 3.


The fate of P2Y-related orphan receptors: GPR80/99 and GPR91 are receptors of dicarboxylic acids.

Gonzalez NS, Communi D, Hannedouche S, Boeynaems JM.

Purinergic Signal. 2004 Dec;1(1):17-20. doi: 10.1007/s11302-004-5071-6.

Supplemental Content

Loading ...
Support Center