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Items: 1 to 50 of 79

1.

Exploration of Physiological and Pathophysiological Implications of miRNA-143 and miRNA-145 in Cerebral Arteries.

Christensen ST, Johansson SE, Warfvinge K, Braun T, Boettger T, Edvinsson L, Haanes KA.

J Cardiovasc Pharmacol. 2019 Nov;74(5):409-419. doi: 10.1097/FJC.0000000000000735.

PMID:
31425342
2.

Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET.

Jia Y, Vong JS, Asafova A, Garvalov BK, Caputo L, Cordero J, Singh A, Boettger T, Günther S, Fink L, Acker T, Barreto G, Seeger W, Braun T, Savai R, Dobreva G.

J Exp Med. 2019 Jun 3;216(6):1377-1395. doi: 10.1084/jem.20181394. Epub 2019 Apr 23.

3.

Deubiquitinase USP10 regulates Notch signaling in the endothelium.

Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Krüger M, Benedito R, Dikic I, Potente M.

Science. 2019 Apr 12;364(6436):188-193. doi: 10.1126/science.aat0778.

PMID:
30975888
4.

Choice of binding sites for CTCFL compared to CTCF is driven by chromatin and by sequence preference.

Bergmaier P, Weth O, Dienstbach S, Boettger T, Galjart N, Mernberger M, Bartkuhn M, Renkawitz R.

Nucleic Acids Res. 2018 Aug 21;46(14):7097-7107. doi: 10.1093/nar/gky483.

5.

Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster.

Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, Bonke E, Günther S, Gärtner U, Boettger T, Braun T.

Cell Metab. 2018 May 1;27(5):1026-1039.e6. doi: 10.1016/j.cmet.2018.02.022. Epub 2018 Apr 5.

6.

Loss of Vascular Myogenic Tone in miR-143/145 Knockout Mice Is Associated With Hypertension-Induced Vascular Lesions in Small Mesenteric Arteries.

Holmberg J, Bhattachariya A, Alajbegovic A, Rippe C, Ekman M, Dahan D, Hien TT, Boettger T, Braun T, Swärd K, Hellstrand P, Albinsson S.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):414-424. doi: 10.1161/ATVBAHA.117.310499. Epub 2017 Dec 7.

PMID:
29217510
7.

The tumor suppressor RASSF1A induces the YAP1 target gene ANKRD1 that is epigenetically inactivated in human cancers and inhibits tumor growth.

Jiménez AP, Traum A, Boettger T, Hackstein H, Richter AM, Dammann RH.

Oncotarget. 2017 May 23;8(51):88437-88452. doi: 10.18632/oncotarget.18177. eCollection 2017 Oct 24.

8.

The Microbial Metabolite Butyrate Induces Expression of Th1-Associated Factors in CD4+ T Cells.

Kespohl M, Vachharajani N, Luu M, Harb H, Pautz S, Wolff S, Sillner N, Walker A, Schmitt-Kopplin P, Boettger T, Renz H, Offermanns S, Steinhoff U, Visekruna A.

Front Immunol. 2017 Aug 28;8:1036. doi: 10.3389/fimmu.2017.01036. eCollection 2017.

9.

Factor VII activating protease (FSAP) regulates the expression of inflammatory genes in vascular smooth muscle and endothelial cells.

Byskov K, Boettger T, Ruehle PF, Nielsen NV, Etscheid M, Kanse SM.

Atherosclerosis. 2017 Oct;265:133-139. doi: 10.1016/j.atherosclerosis.2017.08.029. Epub 2017 Aug 25.

PMID:
28881271
10.

MicroRNA-Dependent Control of Serotonin-Induced Pulmonary Arterial Contraction.

Dahan D, Hien TT, Tannenberg P, Ekman M, Rippe C, Boettger T, Braun T, Tran-Lundmark K, Tran PK, Swärd K, Albinsson S.

J Vasc Res. 2017;54(4):246-256. doi: 10.1159/000478013. Epub 2017 Aug 11.

PMID:
28796998
11.

Sex-specific, reciprocal regulation of ERα and miR-22 controls muscle lipid metabolism in male mice.

Schweisgut J, Schutt C, Wüst S, Wietelmann A, Ghesquière B, Carmeliet P, Dröse S, Korach KS, Braun T, Boettger T.

EMBO J. 2017 May 2;36(9):1199-1214. doi: 10.15252/embj.201695988. Epub 2017 Mar 17.

12.

tBRD-1 and tBRD-2 regulate expression of genes necessary for spermatid differentiation.

Theofel I, Bartkuhn M, Boettger T, Gärtner SMK, Kreher J, Brehm A, Rathke C.

Biol Open. 2017 Apr 15;6(4):439-448. doi: 10.1242/bio.022467.

13.

Carbon storage potential in size-density fractions from semi-natural grassland ecosystems with different productivities over varying soil depths.

Breulmann M, Boettger T, Buscot F, Gruendling R, Schulz E.

Sci Total Environ. 2016 Mar 1;545-546:30-9. doi: 10.1016/j.scitotenv.2015.12.050. Epub 2015 Dec 30.

PMID:
26745290
14.

FOXO1 couples metabolic activity and growth state in the vascular endothelium.

Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich MF, Lim R, Zimmermann B, Aspalter IM, Franco CA, Boettger T, Braun T, Fruttiger M, Rajewsky K, Keller C, Brüning JC, Gerhardt H, Carmeliet P, Potente M.

Nature. 2016 Jan 14;529(7585):216-20. doi: 10.1038/nature16498. Epub 2016 Jan 6.

15.

Elevated Glucose Levels Promote Contractile and Cytoskeletal Gene Expression in Vascular Smooth Muscle via Rho/Protein Kinase C and Actin Polymerization.

Hien TT, Turczyńska KM, Dahan D, Ekman M, Grossi M, Sjögren J, Nilsson J, Braun T, Boettger T, Garcia-Vaz E, Stenkula K, Swärd K, Gomez MF, Albinsson S.

J Biol Chem. 2016 Feb 12;291(7):3552-68. doi: 10.1074/jbc.M115.654384. Epub 2015 Dec 18.

16.

Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality.

Kraut B, Maier HJ, Kókai E, Fiedler K, Boettger T, Illing A, Kostin S, Walther P, Braun T, Wirth T.

PLoS One. 2015 Nov 5;10(11):e0141591. doi: 10.1371/journal.pone.0141591. eCollection 2015.

17.

Deficient acid handling with distal RTA in the NBCe2 knockout mouse.

Wen D, Yuan Y, Cornelius RJ, Li H, Warner PC, Wang B, Wang-France J, Boettger T, Sansom SC.

Am J Physiol Renal Physiol. 2015 Sep 15;309(6):F523-30. doi: 10.1152/ajprenal.00163.2015. Epub 2015 Jun 24.

18.

Spontaneous activity and stretch-induced contractile differentiation are reduced in vascular smooth muscle of miR-143/145 knockout mice.

Bhattachariya A, Dahan D, Ekman M, Boettger T, Braun T, Swärd K, Hellstrand P, Albinsson S.

Acta Physiol (Oxf). 2015 Nov;215(3):133-43. doi: 10.1111/apha.12536. Epub 2015 Jun 24.

PMID:
26052659
19.

Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions.

Gurav A, Sivaprakasam S, Bhutia YD, Boettger T, Singh N, Ganapathy V.

Biochem J. 2015 Jul 15;469(2):267-78. doi: 10.1042/BJ20150242. Epub 2015 May 18.

20.

Increased Epithelial Sodium Channel Activity Contributes to Hypertension Caused by Na+-HCO3- Cotransporter Electrogenic 2 Deficiency.

Wen D, Yuan Y, Warner PC, Wang B, Cornelius RJ, Wang-France J, Li H, Boettger T, Sansom SC.

Hypertension. 2015 Jul;66(1):68-74. doi: 10.1161/HYPERTENSIONAHA.115.05394. Epub 2015 May 4.

21.

Myocardial healing requires Reg3β-dependent accumulation of macrophages in the ischemic heart.

Lörchner H, Pöling J, Gajawada P, Hou Y, Polyakova V, Kostin S, Adrian-Segarra JM, Boettger T, Wietelmann A, Warnecke H, Richter M, Kubin T, Braun T.

Nat Med. 2015 Apr;21(4):353-62. doi: 10.1038/nm.3816. Epub 2015 Mar 9.

PMID:
25751817
22.

The miR-206/133b cluster is dispensable for development, survival and regeneration of skeletal muscle.

Boettger T, Wüst S, Nolte H, Braun T.

Skelet Muscle. 2014 Dec 12;4(1):23. doi: 10.1186/s13395-014-0023-5. eCollection 2014.

23.

MiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization.

Besser J, Malan D, Wystub K, Bachmann A, Wietelmann A, Sasse P, Fleischmann BK, Braun T, Boettger T.

PLoS One. 2014 Nov 21;9(11):e113449. doi: 10.1371/journal.pone.0113449. eCollection 2014.

24.

Patient-specific biomechanical model for the prediction of lung motion from 4-D CT images.

Fuerst B, Mansi T, Carnis F, Salzle M, Zhang J, Declerck J, Boettger T, Bayouth J, Navab N, Kamen A.

IEEE Trans Med Imaging. 2015 Feb;34(2):599-607. doi: 10.1109/TMI.2014.2363611. Epub 2014 Oct 16.

PMID:
25343757
25.

Induction of angiotensin-converting enzyme after miR-143/145 deletion is critical for impaired smooth muscle contractility.

Dahan D, Ekman M, Larsson-Callerfelt AK, Turczyńska K, Boettger T, Braun T, Swärd K, Albinsson S.

Am J Physiol Cell Physiol. 2014 Dec 15;307(12):C1093-101. doi: 10.1152/ajpcell.00250.2014. Epub 2014 Oct 1.

26.

tBRD-1 selectively controls gene activity in the Drosophila testis and interacts with two new members of the bromodomain and extra-terminal (BET) family.

Theofel I, Bartkuhn M, Hundertmark T, Boettger T, Gärtner SM, Leser K, Awe S, Schipper M, Renkawitz-Pohl R, Rathke C.

PLoS One. 2014 Sep 24;9(9):e108267. doi: 10.1371/journal.pone.0108267. eCollection 2014.

27.

Spatial variability and temporal trends in water-use efficiency of European forests.

Saurer M, Spahni R, Frank DC, Joos F, Leuenberger M, Loader NJ, McCarroll D, Gagen M, Poulter B, Siegwolf RT, Andreu-Hayles L, Boettger T, Dorado Liñán I, Fairchild IJ, Friedrich M, Gutierrez E, Haupt M, Hilasvuori E, Heinrich I, Helle G, Grudd H, Jalkanen R, Levanič T, Linderholm HW, Robertson I, Sonninen E, Treydte K, Waterhouse JS, Woodley EJ, Wynn PM, Young GH.

Glob Chang Biol. 2014 Dec;20(12):3700-12. doi: 10.1111/gcb.12717. Epub 2014 Sep 22.

PMID:
25156251
28.

Myostatin regulates energy homeostasis in the heart and prevents heart failure.

Biesemann N, Mendler L, Wietelmann A, Hermann S, Schäfers M, Krüger M, Boettger T, Borchardt T, Braun T.

Circ Res. 2014 Jul 7;115(2):296-310. doi: 10.1161/CIRCRESAHA.115.304185. Epub 2014 May 7.

PMID:
24807786
29.

Hmga2 is required for canonical WNT signaling during lung development.

Singh I, Mehta A, Contreras A, Boettger T, Carraro G, Wheeler M, Cabrera-Fuentes HA, Bellusci S, Seeger W, Braun T, Barreto G.

BMC Biol. 2014 Mar 24;12:21. doi: 10.1186/1741-7007-12-21.

30.

Reduced climate sensitivity of carbon, oxygen and hydrogen stable isotope ratios in tree-ring cellulose of silver fir (Abies alba Mill.) influenced by background SO2 in Franconia (Germany, Central Europe).

Boettger T, Haupt M, Friedrich M, Waterhouse JS.

Environ Pollut. 2014 Feb;185:281-94. doi: 10.1016/j.envpol.2013.10.030. Epub 2013 Dec 3.

PMID:
24316066
31.

Therapeutic targeting of the oncostatin M receptor-β prevents inflammatory heart failure.

Pöling J, Gajawada P, Richter M, Lörchner H, Polyakova V, Kostin S, Shin J, Boettger T, Walther T, Rees W, Wietelmann A, Warnecke H, Kubin T, Braun T.

Basic Res Cardiol. 2014 Jan;109(1):396. doi: 10.1007/s00395-013-0396-3. Epub 2013 Nov 29.

PMID:
24292852
32.

Overexpression of Twinkle-helicase protects cardiomyocytes from genotoxic stress caused by reactive oxygen species.

Pohjoismäki JL, Williams SL, Boettger T, Goffart S, Kim J, Suomalainen A, Moraes CT, Braun T.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19408-13. doi: 10.1073/pnas.1303046110. Epub 2013 Nov 11.

33.

Quantitative proteome analysis of alveolar type-II cells reveals a connection of integrin receptor subunits beta 2/6 and WNT signaling.

Mukhametshina RT, Ruhs A, Singh I, Hasan D, Contreras A, Mehta A, Nikam VS, Ahlbrecht K, Carraro G, Cabrera-Fuentes HA, Jiang D, Voswinckel R, Seeger W, Bellusci S, Scharffetter-Kochanek K, Bagaeva TV, Preissner KT, Boettger T, Braun T, Krüger M, Barreto G.

J Proteome Res. 2013 Dec 6;12(12):5598-608. doi: 10.1021/pr400573k. Epub 2013 Nov 18.

PMID:
24175614
34.

miR-1/133a clusters cooperatively specify the cardiomyogenic lineage by adjustment of myocardin levels during embryonic heart development.

Wystub K, Besser J, Bachmann A, Boettger T, Braun T.

PLoS Genet. 2013;9(9):e1003793. doi: 10.1371/journal.pgen.1003793. Epub 2013 Sep 19.

35.

Molecular mechanism of SLC5A8 inactivation in breast cancer.

Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M.

Mol Cell Biol. 2013 Oct;33(19):3920-35. doi: 10.1128/MCB.01702-12. Epub 2013 Aug 5.

36.

AMP-activated protein kinase regulates endothelial cell angiotensin-converting enzyme expression via p53 and the post-transcriptional regulation of microRNA-143/145.

Kohlstedt K, Trouvain C, Boettger T, Shi L, Fisslthaler B, Fleming I.

Circ Res. 2013 Apr 12;112(8):1150-8. doi: 10.1161/CIRCRESAHA.113.301282. Epub 2013 Mar 8.

PMID:
23476055
37.

Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate.

Ananth S, Babu E, Veeranan-Karmegam R, Bozard Baldowski BR, Boettger T, Martin PM.

Invest Ophthalmol Vis Sci. 2013 Mar 1;54(3):1592-602. doi: 10.1167/iovs.12-11289.

PMID:
23404113
38.

Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences.

Günther K, Rust M, Leers J, Boettger T, Scharfe M, Jarek M, Bartkuhn M, Renkawitz R.

Nucleic Acids Res. 2013 Mar 1;41(5):3010-21. doi: 10.1093/nar/gkt035. Epub 2013 Jan 29.

39.

A personalized biomechanical model for respiratory motion prediction.

Fuerst B, Mansi T, Zhang J, Khurd P, Declerck J, Boettger T, Navab N, Bayouth J, Comaniciu D, Kamen A.

Med Image Comput Comput Assist Interv. 2012;15(Pt 3):566-73.

40.

Precise segmentation of multiple organs in CT volumes using learning-based approach and information theory.

Lu C, Zheng Y, Birkbeck N, Zhang J, Kohlberger T, Tietjen C, Boettger T, Duncan JS, Zhou SK.

Med Image Comput Comput Assist Interv. 2012;15(Pt 2):462-9.

PMID:
23286081
41.

G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure.

Takefuji M, Wirth A, Lukasova M, Takefuji S, Boettger T, Braun T, Althoff T, Offermanns S, Wettschureck N.

Circulation. 2012 Oct 16;126(16):1972-82. doi: 10.1161/CIRCULATIONAHA.112.109256. Epub 2012 Sep 12.

PMID:
22972902
43.

Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response.

Pohjoismäki JL, Boettger T, Liu Z, Goffart S, Szibor M, Braun T.

Nucleic Acids Res. 2012 Aug;40(14):6595-607. doi: 10.1093/nar/gks301. Epub 2012 Apr 15.

44.

A new level of complexity: the role of microRNAs in cardiovascular development.

Boettger T, Braun T.

Circ Res. 2012 Mar 30;110(7):1000-13. doi: 10.1161/CIRCRESAHA.111.247742. Review.

PMID:
22461364
45.

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.

Hergenreider E, Heydt S, Tréguer K, Boettger T, Horrevoets AJ, Zeiher AM, Scheffer MP, Frangakis AS, Yin X, Mayr M, Braun T, Urbich C, Boon RA, Dimmeler S.

Nat Cell Biol. 2012 Feb 12;14(3):249-56. doi: 10.1038/ncb2441.

PMID:
22327366
46.

On marathons and Sprints: an integrated quantitative proteomics and transcriptomics analysis of differences between slow and fast muscle fibers.

Drexler HC, Ruhs A, Konzer A, Mendler L, Bruckskotten M, Looso M, Günther S, Boettger T, Krüger M, Braun T.

Mol Cell Proteomics. 2012 Jun;11(6):M111.010801. doi: 10.1074/mcp.M111.010801. Epub 2011 Dec 30.

47.

Targeted mutation of SLC4A5 induces arterial hypertension and renal metabolic acidosis.

Gröger N, Vitzthum H, Fröhlich H, Krüger M, Ehmke H, Braun T, Boettger T.

Hum Mol Genet. 2012 Mar 1;21(5):1025-36. doi: 10.1093/hmg/ddr533. Epub 2011 Nov 14.

PMID:
22082831
48.
49.

Transport via SLC5A8 (SMCT1) is obligatory for 2-oxothiazolidine-4-carboxylate to enhance glutathione production in retinal pigment epithelial cells.

Babu E, Ananth S, Veeranan-Karmegam R, Coothankandaswamy V, Smith SB, Boettger T, Ganapathy V, Martin PM.

Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):5749-57. doi: 10.1167/iovs.10-6825.

50.

Identification of right heart-enriched genes in a murine model of chronic outflow tract obstruction.

Kreymborg Kg, Uchida S, Gellert P, Schneider A, Boettger T, Voswinckel R, Wietelmann A, Szibor M, Weissmann N, Ghofrani AH, Schermuly R, Schranz D, Seeger W, Braun T.

J Mol Cell Cardiol. 2010 Oct;49(4):598-605. doi: 10.1016/j.yjmcc.2010.07.014. Epub 2010 Jul 27.

PMID:
20673770

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