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Items: 1 to 50 of 93

1.

Publication status of completed registered studies in paediatric appendicitis: a cross-sectional analysis.

Breil T, Boettcher M, Hoffmann GF, Ries M.

BMJ Open. 2018 Jul 16;8(7):e021684. doi: 10.1136/bmjopen-2018-021684.

2.

Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin.

Tromp AT, Van Gent M, Abrial P, Martin A, Jansen JP, De Haas CJC, Van Kessel KPM, Bardoel BW, Kruse E, Bourdonnay E, Boettcher M, McManus MT, Day CJ, Jennings MP, Lina G, Vandenesch F, Van Strijp JAG, Jan Lebbink R, Haas PA, Henry T, Spaan AN.

Nat Microbiol. 2018 Jun;3(6):708-717. doi: 10.1038/s41564-018-0159-x. Epub 2018 May 7.

PMID:
29736038
3.

Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation.

Shang W, Jiang Y, Boettcher M, Ding K, Mollenauer M, Liu Z, Wen X, Liu C, Hao P, Zhao S, McManus MT, Wei L, Weiss A, Wang H.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4051-E4060. doi: 10.1073/pnas.1801340115. Epub 2018 Apr 9.

PMID:
29632189
4.

Dual gene activation and knockout screen reveals directional dependencies in genetic networks.

Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT.

Nat Biotechnol. 2018 Feb;36(2):170-178. doi: 10.1038/nbt.4062. Epub 2018 Jan 15.

5.

Corrigendum to Induction of autophagy reduces ischemia/reperfusion injury in steatotic rat livers [Journal of Surgical Research 216 (2017) 207-218].

Kan C, Liu A, Fang H, Dirsch O, Dahmen U, Boettcher M.

J Surg Res. 2018 Jan 3. pii: S0022-4804(17)30728-X. doi: 10.1016/j.jss.2017.11.040. [Epub ahead of print] No abstract available.

PMID:
29306480
6.

[Undetected Cases of Non-Accidental Burns in Children - Preventive Strategies].

Klinke M, Schmidt CM, Tegtmeyer L, Reinshagen K, Boettcher M, Koenigs I.

Klin Padiatr. 2018 Mar;230(2):61-67. doi: 10.1055/s-0043-119416. Epub 2017 Dec 19. German.

PMID:
29258160
7.

Therapeutic targeting of extracellular DNA improves the outcome of intestinal ischemic reperfusion injury in neonatal rats.

Boettcher M, Eschenburg G, Mietzsch S, Jiménez-Alcázar M, Klinke M, Vincent D, Tiemann B, Bergholz R, Reinshagen K, Fuchs TA.

Sci Rep. 2017 Nov 13;7(1):15377. doi: 10.1038/s41598-017-15807-6.

8.

Induction of autophagy reduces ischemia/reperfusion injury in steatotic rat livers.

Kan C, Liu A, Fang H, Dirsch O, Dahmen U, Boettcher M.

J Surg Res. 2017 Aug;216:207-218. doi: 10.1016/j.jss.2017.04.012. Epub 2017 Apr 20. Erratum in: J Surg Res. 2018 Jan 3;:.

PMID:
28807209
9.

Degradation of Extracellular DNA by DNase1 Significantly Reduces Testicular Damage After Testicular Torsion in Rats.

Boettcher M, Meier D, Jiménez-Alcázar M, Eschenburg G, Mietzsch S, Vincent D, Klinke M, Trochimiuk M, Appl B, Tiemann B, Bergholz R, Reinshagen K, Fuchs TA.

Urology. 2017 Nov;109:223.e1-223.e7. doi: 10.1016/j.urology.2017.07.031. Epub 2017 Jul 31.

PMID:
28774773
10.

The spaced learning concept significantly improves training for laparoscopic suturing: a pilot randomized controlled study.

Boettcher M, Boettcher J, Mietzsch S, Krebs T, Bergholz R, Reinshagen K.

Surg Endosc. 2018 Jan;32(1):154-159. doi: 10.1007/s00464-017-5650-6. Epub 2017 Jun 22.

PMID:
28643052
11.

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.

Krebs AM, Mitschke J, Lasierra Losada M, Schmalhofer O, Boerries M, Busch H, Boettcher M, Mougiakakos D, Reichardt W, Bronsert P, Brunton VG, Pilarsky C, Winkler TH, Brabletz S, Stemmler MP, Brabletz T.

Nat Cell Biol. 2017 May;19(5):518-529. doi: 10.1038/ncb3513. Epub 2017 Apr 17.

PMID:
28414315
12.

[Acute Kidney Failure Due to Urachal Cyst?]

Klaassen I, Wolf M, Kemper MJ, Riechardt S, Boettcher M, Herrmann J, Singer D.

Z Geburtshilfe Neonatol. 2017 Apr;221(2):88-91. doi: 10.1055/s-0042-111397. Epub 2017 Mar 9. German.

PMID:
28278526
13.

Pharmacokinetics and safety of nifedipine GITS/candesartan fixed-dose combination in subjects with hepatic impairment
.

Liu Y, Boettcher MF, Schmidt A, Unger S, Halabi A, Brendel E, Blode H.

Int J Clin Pharmacol Ther. 2017 Mar;55(3):246-255. doi: 10.5414/CP202700.

PMID:
28025965
14.

The Heidelberg Appendicitis Score Predicts Perforated Appendicitis in Children.

Boettcher M, Günther P, Breil T.

Clin Pediatr (Phila). 2017 Oct;56(12):1115-1119. doi: 10.1177/0009922816678976. Epub 2016 Nov 20.

PMID:
27872360
15.

Dissection of CD20 regulation in lymphoma using RNAi.

Słabicki M, Lee KS, Jethwa A, Sellner L, Sacco F, Walther T, Hüllein J, Dietrich S, Wu B, Lipka DB, Oakes CC, Mamidi S, Pyrzyńska B, Winiarska M, Oleś M, Seifert M, Plass C, Kirschfink M, Boettcher M, Gołąb J, Huber W, Fröhling S, Zenz T.

Leukemia. 2016 Dec;30(12):2409-2412. doi: 10.1038/leu.2016.230. Epub 2016 Aug 18. No abstract available.

PMID:
27560109
16.

The Heidelberg Appendicitis Score Simplifies Identification of Pediatric Appendicitis.

Boettcher M, Breil T, Günther P.

Indian J Pediatr. 2016 Oct;83(10):1093-7. doi: 10.1007/s12098-016-2106-2. Epub 2016 Apr 26.

PMID:
27115891
17.

Dual-Energy CT-based Display of Bone Marrow Edema in Osteoporotic Vertebral Compression Fractures: Impact on Diagnostic Accuracy of Radiologists with Varying Levels of Experience in Correlation to MR Imaging.

Kaup M, Wichmann JL, Scholtz JE, Beeres M, Kromen W, Albrecht MH, Lehnert T, Boettcher M, Vogl TJ, Bauer RW.

Radiology. 2016 Aug;280(2):510-9. doi: 10.1148/radiol.2016150472. Epub 2016 Feb 29.

PMID:
26928067
18.

Rare Case of Excessive Beta-Human Chorionic Gonadotropin Producing Intrascrotal Leiomyosarcoma: Diagnostic Pitfalls and Therapeutic Implications.

Brandt MP, Hoefner T, Gust KM, Ahrens M, Boettcher M, Kvasnicka HM, Bartsch G, Thomas C, Haferkamp A, Tsaur I.

Clin Genitourin Cancer. 2016 Aug;14(4):e409-12. doi: 10.1016/j.clgc.2016.01.009. Epub 2016 Jan 22. No abstract available.

PMID:
26873434
19.

IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration.

Kulkarni U, Karsten CM, Kohler T, Hammerschmidt S, Bommert K, Tiburzy B, Meng L, Thieme L, Recke A, Ludwig RJ, Pollok K, Kalies K, Bogen B, Boettcher M, Kamradt T, Hauser AE, Langer C, Huber-Lang M, Finkelman FD, Köhl J, Wong DM, Manz RA.

J Allergy Clin Immunol. 2016 May;137(5):1487-1497.e6. doi: 10.1016/j.jaci.2015.10.018. Epub 2015 Dec 2.

PMID:
26653800
20.

Modulation of Thrombosis Significantly Reduces Testicular Damage after Testicular Torsion in Rats: Anti-Thrombotic Treatment and Testicular Torsion.

Boettcher M, Fuchs TA, Schäfer H, Appl B, Trochimiuk M, Jiménez-Alcázar M, Tiemann B, Jung R, Bergholz R, Reinshagen K, Eschenburg G.

Urology. 2016 Feb;88:227.e1-7. doi: 10.1016/j.urology.2015.11.004. Epub 2015 Nov 11.

PMID:
26577621
21.

Training Significantly Improves Fetoscopy Performance: A Pilot Randomized Controlled Trial.

Mietzsch S, Boettcher J, Yang S, Chantereau P, Romero P, Bergholz R, Reinshagen K, Boettcher M.

Eur J Pediatr Surg. 2016 Oct;26(5):436-442. Epub 2015 Oct 7.

PMID:
26445354
22.

Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR.

Boettcher M, McManus MT.

Mol Cell. 2015 May 21;58(4):575-85. doi: 10.1016/j.molcel.2015.04.028. Review.

23.

Implementing highly specialized and evidence-based pediatric eating disorder treatment: protocol for a mixed methods evaluation.

Couturier J, Kimber M, Lock J, Barwick M, McVey G, Findlay S, Webb C, Boettcher M, Niccols A, Woodford T.

Implement Sci. 2015 Mar 28;10:40. doi: 10.1186/s13012-015-0231-3.

24.

Inter-subject variability effects on the primary stability of a short cementless femoral stem.

Bah MT, Shi J, Heller MO, Suchier Y, Lefebvre F, Young P, King L, Dunlop DG, Boettcher M, Draper E, Browne M.

J Biomech. 2015 Apr 13;48(6):1032-42. doi: 10.1016/j.jbiomech.2015.01.037. Epub 2015 Feb 7.

PMID:
25724937
25.

Role of dynamic capsomere supply for viral capsid self-assembly.

Boettcher MA, Klein HC, Schwarz US.

Phys Biol. 2015 Jan 30;12(1):016014. doi: 10.1088/1478-3975/12/1/016014.

PMID:
25635407
26.

Evaluation of a dual-room sliding gantry CT concept for workflow optimisation in polytrauma and regular in- and outpatient management.

Frellesen C, Boettcher M, Wichmann JL, Drieske M, Kerl JM, Lehnert T, Nau C, Geiger E, Wutzler S, Ackermann H, Vogl TJ, Bauer RW.

Eur J Radiol. 2015 Jan;84(1):117-122. doi: 10.1016/j.ejrad.2014.10.013. Epub 2014 Nov 1.

PMID:
25467230
27.

Complex gastroschisis is a different entity to simple gastroschisis affecting morbidity and mortality-a systematic review and meta-analysis.

Bergholz R, Boettcher M, Reinshagen K, Wenke K.

J Pediatr Surg. 2014 Oct;49(10):1527-32. doi: 10.1016/j.jpedsurg.2014.08.001. Epub 2014 Sep 4. Review.

PMID:
25280661
28.

Early prediction of complex midgut volvulus in neonates and infants.

Kanellos-Becker I, Bergholz R, Reinshagen K, Boettcher M.

Pediatr Surg Int. 2014 Jun;30(6):579-86. doi: 10.1007/s00383-014-3504-z. Epub 2014 Apr 23.

PMID:
24756336
29.

Gut inflammation and expression of ICC in a fetal lamb model of fetoscopic intervention for gastroschisis.

Krebs T, Boettcher M, Schäfer H, Eschenburg G, Wenke K, Appl B, Roth B, Andreas T, Schmitz C, Fahje R, Jacobsen B, Tiemann B, Reinshagen K, Hecher K, Bergholz R.

Surg Endosc. 2014 Aug;28(8):2437-42. doi: 10.1007/s00464-014-3494-x. Epub 2014 Mar 20.

PMID:
24648107
30.

Midterm outcome of transumbilically laparoscopic-assisted versus laparoscopic and open appendectomy in children--a matched prospective study.

Bergholz R, Klein I, Wenke K, Boettcher M, Reinshagen K, Krebs T.

Eur J Pediatr Surg. 2015 Apr;25(2):216-9. doi: 10.1055/s-0034-1370782. Epub 2014 Mar 12.

PMID:
24623454
31.

High throughput synthetic lethality screen reveals a tumorigenic role of adenylate cyclase in fumarate hydratase-deficient cancer cells.

Boettcher M, Lawson A, Ladenburger V, Fredebohm J, Wolf J, Hoheisel JD, Frezza C, Shlomi T.

BMC Genomics. 2014 Feb 25;15:158. doi: 10.1186/1471-2164-15-158.

32.

Prenatal latex sensitization in patients with spina bifida: a pilot study.

Boettcher M, Goettler S, Eschenburg G, Kracht T, Kunkel P, Von der Wense A, Reinshagen K.

J Neurosurg Pediatr. 2014 Mar;13(3):291-4. doi: 10.3171/2013.12.PEDS13402. Epub 2014 Jan 3.

PMID:
24404967
33.

An in vivo RNAi screen identifies SALL1 as a tumor suppressor in human breast cancer with a role in CDH1 regulation.

Wolf J, Müller-Decker K, Flechtenmacher C, Zhang F, Shahmoradgoli M, Mills GB, Hoheisel JD, Boettcher M.

Oncogene. 2014 Aug 14;33(33):4273-8. doi: 10.1038/onc.2013.515. Epub 2013 Dec 2.

PMID:
24292671
34.

A mammosphere formation RNAi screen reveals that ATG4A promotes a breast cancer stem-like phenotype.

Wolf J, Dewi DL, Fredebohm J, Müller-Decker K, Flechtenmacher C, Hoheisel JD, Boettcher M.

Breast Cancer Res. 2013 Nov 14;15(6):R109. doi: 10.1186/bcr3576.

35.

Concomitant bilateral adnexal entanglement in a 7-year-old girl with precocious puberty.

Boettcher M, Kanellos-Becker I, Akkurt I, Reinshagen K.

Int J Gynaecol Obstet. 2013 Dec;123(3):248-9. doi: 10.1016/j.ijgo.2013.06.021. Epub 2013 Aug 30. No abstract available.

PMID:
24055169
36.

Clinical and sonographic features predict testicular torsion in children: a prospective study.

Boettcher M, Krebs T, Bergholz R, Wenke K, Aronson D, Reinshagen K.

BJU Int. 2013 Dec;112(8):1201-6. doi: 10.1111/bju.12229. Epub 2013 Jul 4.

37.

Differentiation of epididymitis and appendix testis torsion by clinical and ultrasound signs in children.

Boettcher M, Bergholz R, Krebs TF, Wenke K, Treszl A, Aronson DC, Reinshagen K.

Urology. 2013 Oct;82(4):899-904. doi: 10.1016/j.urology.2013.04.004. Epub 2013 Jun 2.

PMID:
23735611
38.

Depletion of RAD17 sensitizes pancreatic cancer cells to gemcitabine.

Fredebohm J, Wolf J, Hoheisel JD, Boettcher M.

J Cell Sci. 2013 Aug 1;126(Pt 15):3380-9. doi: 10.1242/jcs.124768. Epub 2013 May 17.

39.

Rectum perforation after broomstick impalement in a 17-year-old: case report and review.

Boettcher M, Kanellos-Becker I, Wenke K, Krebs TF.

Pediatr Emerg Care. 2013 Apr;29(4):510-2. doi: 10.1097/PEC.0b013e31828a3a3d. Review.

PMID:
23558271
40.

Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model system.

Fredebohm J, Boettcher M, Eisen C, Gaida MM, Heller A, Keleg S, Tost J, Greulich-Bode KM, Hotz-Wagenblatt A, Lathrop M, Giese NA, Hoheisel JD.

PLoS One. 2012;7(11):e48503. doi: 10.1371/journal.pone.0048503. Epub 2012 Nov 12.

41.

Abdominal wall incision with or without exteriorization of bowel: results from a fetal lamb model for the embryogenesis of gastroschisis.

Bergholz R, Krebs T, Wenke K, Boettcher M, Andreas T, Tiemann B, Jacobsen B, Fahje R, Schmitz C, Roth B, Appl B, Reinshagen K, Hecher K.

Fetal Diagn Ther. 2013;33(1):55-60. doi: 10.1159/000342421. Epub 2012 Nov 3.

PMID:
23128037
42.

Currarinot triade.

Boettcher M, Krebs TF.

ANZ J Surg. 2012 Apr;82(4):275. doi: 10.1111/j.1445-2197.2012.06013.x. No abstract available.

PMID:
22510187
43.

Noninvasive stratum corneum sampling and electron microscopical examination of skin barrier integrity: pilot study with a topical glycerin formulation for atopic dermatitis.

Daehnhardt-Pfeiffer S, Surber C, Wilhelm KP, Daehnhardt D, Springmann G, Boettcher M, Foelster-Holst R.

Skin Pharmacol Physiol. 2012;25(3):155-61. doi: 10.1159/000336789. Epub 2012 Mar 6.

PMID:
22399038
44.

Clinical predictors of testicular torsion in children.

Boettcher M, Bergholz R, Krebs TF, Wenke K, Aronson DC.

Urology. 2012 Mar;79(3):670-4. doi: 10.1016/j.urology.2011.10.041.

PMID:
22386422
45.

ER-alpha-cDNA as part of a bicistronic transcript gives rise to high frequency, long term, receptor expressing cell clones.

Shenfeld M, Hachmo Y, Frenkel M, Dafni N, Boettcher M, Hoheisel JD, Dotan I, Canaani D.

PLoS One. 2012;7(2):e31977. doi: 10.1371/journal.pone.0031977. Epub 2012 Feb 20.

46.

Selective 5-HT(1A)-R-agonist repinotan prevents remifentanil-induced ventilatory depression and prolongs antinociception.

Guenther U, Theuerkauf NU, Huse D, Boettcher MF, Wensing G, Putensen C, Hoeft A.

Anesthesiology. 2012 Jan;116(1):56-64. doi: 10.1097/ALN.0b013e31823d08fa.

PMID:
22082683
47.

Overactive bladder syndrome: an underestimated long-term problem after treatment of patients with localized prostate cancer?

Boettcher M, Haselhuhn A, Jakse G, Brehmer B, Kirschner-Hermanns R.

BJU Int. 2012 Jun;109(12):1824-30. doi: 10.1111/j.1464-410X.2011.10623.x. Epub 2011 Sep 27.

48.

Single dose pharmacokinetics, pharmacodynamics, tolerability and safety of BAY 60-5521, a potent inhibitor of cholesteryl ester transfer protein.

Boettcher MF, Heinig R, Schmeck C, Kohlsdorfer C, Ludwig M, Schaefer A, Gelfert-Peukert S, Wensing G, Weber O.

Br J Clin Pharmacol. 2012 Feb;73(2):210-8. doi: 10.1111/j.1365-2125.2011.04083.x.

49.

Filtration at the microfluidic level: enrichment of nanoparticles by tunable filters.

Boettcher M, Schmidt S, Latz A, Jaeger MS, Stuke M, Duschl C.

J Phys Condens Matter. 2011 Aug 17;23(32):324101. doi: 10.1088/0953-8984/23/32/324101. Epub 2011 Jul 27.

PMID:
21795763
50.

Assessment of LED fluorescence microscopy for the diagnosis of Plasmodium falciparum infections in Gabon.

Lenz D, Kremsner PG, Lell B, Biallas B, Boettcher M, Mordmüller B, Adegnika AA.

Malar J. 2011 Jul 18;10:194. doi: 10.1186/1475-2875-10-194.

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