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Items: 15

1.

Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A.

Wójcik M, Eleftheriadis N, Zwinderman MRH, Dömling ASS, Dekker FJ, Boersma YL.

Eur J Med Chem. 2019 Jan 1;161:93-100. doi: 10.1016/j.ejmech.2018.10.027. Epub 2018 Oct 15.

PMID:
30343193
2.

Advances in the Application of Designed Ankyrin Repeat Proteins (DARPins) as Research Tools and Protein Therapeutics.

Boersma YL.

Methods Mol Biol. 2018;1798:307-327. doi: 10.1007/978-1-4939-7893-9_23. Review.

PMID:
29868969
3.

Novel RANKL DE-loop mutants antagonize RANK-mediated osteoclastogenesis.

Wang Y, van Assen AHG, Reis CR, Setroikromo R, van Merkerk R, Boersma YL, Cool RH, Quax WJ.

FEBS J. 2017 Aug;284(15):2501-2512. doi: 10.1111/febs.14142. Epub 2017 Jul 7.

4.

High-Throughput Screening in Protein Engineering: Recent Advances and Future Perspectives.

Wójcik M, Telzerow A, Quax WJ, Boersma YL.

Int J Mol Sci. 2015 Oct 20;16(10):24918-45. doi: 10.3390/ijms161024918. Review.

5.

The structure of vanin 1: a key enzyme linking metabolic disease and inflammation.

Boersma YL, Newman J, Adams TE, Cowieson N, Krippner G, Bozaoglu K, Peat TS.

Acta Crystallogr D Biol Crystallogr. 2014 Dec 1;70(Pt 12):3320-9. doi: 10.1107/S1399004714022767. Epub 2014 Nov 28.

PMID:
25478849
6.

The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.

Kiuchi T, Ortiz-Zapater E, Monypenny J, Matthews DR, Nguyen LK, Barbeau J, Coban O, Lawler K, Burford B, Rolfe DJ, de Rinaldis E, Dafou D, Simpson MA, Woodman N, Pinder S, Gillett CE, Devauges V, Poland SP, Fruhwirth G, Marra P, Boersma YL, Plückthun A, Gullick WJ, Yarden Y, Santis G, Winn M, Kholodenko BN, Martin-Fernandez ML, Parker P, Tutt A, Ameer-Beg SM, Ng T.

Sci Signal. 2014 Aug 19;7(339):ra78. doi: 10.1126/scisignal.2005157.

PMID:
25140053
7.

Bispecific designed ankyrin repeat proteins (DARPins) targeting epidermal growth factor receptor inhibit A431 cell proliferation and receptor recycling.

Boersma YL, Chao G, Steiner D, Wittrup KD, Plückthun A.

J Biol Chem. 2011 Dec 2;286(48):41273-85. doi: 10.1074/jbc.M111.293266. Epub 2011 Oct 6.

8.

DARPins and other repeat protein scaffolds: advances in engineering and applications.

Boersma YL, Plückthun A.

Curr Opin Biotechnol. 2011 Dec;22(6):849-57. doi: 10.1016/j.copbio.2011.06.004. Epub 2011 Jun 27. Review.

PMID:
21715155
9.

Loop grafting of Bacillus subtilis lipase A: inversion of enantioselectivity.

Boersma YL, Pijning T, Bosma MS, van der Sloot AM, Godinho LF, Dröge MJ, Winter RT, van Pouderoyen G, Dijkstra BW, Quax WJ.

Chem Biol. 2008 Aug 25;15(8):782-9. doi: 10.1016/j.chembiol.2008.06.009.

10.

A novel genetic selection system for improved enantioselectivity of Bacillus subtilis lipase A.

Boersma YL, Dröge MJ, van der Sloot AM, Pijning T, Cool RH, Dijkstra BW, Quax WJ.

Chembiochem. 2008 May 5;9(7):1110-5. doi: 10.1002/cbic.200700754.

PMID:
18383241
11.

Selection strategies for improved biocatalysts.

Boersma YL, Dröge MJ, Quax WJ.

FEBS J. 2007 May;274(9):2181-95. Review.

12.

HPLC-photodiode array detection analysis of curcuminoids in Curcuma species indigenous to Indonesia.

Bos R, Windono T, Woerdenbag HJ, Boersma YL, Koulman A, Kayser O.

Phytochem Anal. 2007 Mar-Apr;18(2):118-22.

PMID:
17439012
13.

Phage display of an intracellular carboxylesterase of Bacillus subtilis: comparison of Sec and Tat pathway export capabilities.

Dröge MJ, Boersma YL, Braun PG, Buining RJ, Julsing MK, Selles KG, van Dijl JM, Quax WJ.

Appl Environ Microbiol. 2006 Jul;72(7):4589-95.

14.

Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection.

Dröge MJ, Boersma YL, van Pouderoyen G, Vrenken TE, Rüggeberg CJ, Reetz MT, Dijkstra BW, Quax WJ.

Chembiochem. 2006 Jan;7(1):149-57.

PMID:
16342303
15.

A validated gas chromatographic method for the evaluation of enzymatic enantioselectivity in kinetic resolution applications.

Boersma YL, Scheltinga PC, Dröge MJ, Bos R, Quax WJ.

J Sep Sci. 2005 Apr;28(6):501-5.

PMID:
15881078

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