Sort by
Items per page

Send to

Choose Destination

Search results

Items: 29


MicroRNAs as possible indicators of drug sensitivity in breast cancer cell lines.

Uhr K, Prager-van der Smissen WJC, Heine AAJ, Ozturk B, van Jaarsveld MTM, Boersma AWM, Jager A, Wiemer EAC, Smid M, Foekens JA, Martens JWM.

PLoS One. 2019 May 7;14(5):e0216400. doi: 10.1371/journal.pone.0216400. eCollection 2019.


MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells.

Nyhan MJ, O'Donovan TR, Boersma AW, Wiemer EA, McKenna SL.

BMC Cancer. 2016 Feb 15;16:101. doi: 10.1186/s12885-016-2123-6.


miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway.

van Jaarsveld MT, van Kuijk PF, Boersma AW, Helleman J, van IJcken WF, Mathijssen RH, Pothof J, Berns EM, Verweij J, Wiemer EA.

Mol Cancer. 2015 Nov 17;14:196. doi: 10.1186/s12943-015-0464-4.


Lysosomal Sequestration Determines Intracellular Imatinib Levels.

Burger H, den Dekker AT, Segeletz S, Boersma AW, de Bruijn P, Debiec-Rychter M, Taguchi T, Sleijfer S, Sparreboom A, Mathijssen RH, Wiemer EA.

Mol Pharmacol. 2015 Sep;88(3):477-87. doi: 10.1124/mol.114.097451. Epub 2015 Jun 24.


DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity.

van Jaarsveld MT, Wouters MD, Boersma AW, Smid M, van Ijcken WF, Mathijssen RH, Hoeijmakers JH, Martens JW, van Laere S, Wiemer EA, Pothof J.

Mol Oncol. 2014 May;8(3):458-68. doi: 10.1016/j.molonc.2013.12.011. Epub 2013 Dec 31.


MicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors.

Gits CM, van Kuijk PF, Jonkers MB, Boersma AW, Smid M, van Ijcken WF, Coindre JM, Chibon F, Verhoef C, Mathijssen RH, den Bakker MA, Verweij J, Sleijfer S, Wiemer EA.

Int J Cancer. 2014 Jul 15;135(2):348-61. doi: 10.1002/ijc.28694. Epub 2014 Jan 16.


MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours.

Gits CM, van Kuijk PF, Jonkers MB, Boersma AW, van Ijcken WF, Wozniak A, Sciot R, Rutkowski P, Schöffski P, Taguchi T, Mathijssen RH, Verweij J, Sleijfer S, Debiec-Rychter M, Wiemer EA.

Br J Cancer. 2013 Sep 17;109(6):1625-35. doi: 10.1038/bjc.2013.483. Epub 2013 Aug 22.


miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs.

Riaz M, van Jaarsveld MT, Hollestelle A, Prager-van der Smissen WJ, Heine AA, Boersma AW, Liu J, Helmijr J, Ozturk B, Smid M, Wiemer EA, Foekens JA, Martens JW.

Breast Cancer Res. 2013 Apr 19;15(2):R33. doi: 10.1186/bcr3415.


miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells.

van Jaarsveld MT, Helleman J, Boersma AW, van Kuijk PF, van Ijcken WF, Despierre E, Vergote I, Mathijssen RH, Berns EM, Verweij J, Pothof J, Wiemer EA.

Oncogene. 2013 Sep 5;32(36):4284-93. doi: 10.1038/onc.2012.433. Epub 2012 Oct 8.


The kinase RSK2 modulates the sensitivity of ovarian cancer cells to cisplatin.

van Jaarsveld MT, Blijdorp IC, Boersma AW, Pothof J, Mathijssen RH, Verweij J, Wiemer EA.

Eur J Cancer. 2013 Jan;49(2):345-51. doi: 10.1016/j.ejca.2012.08.024. Epub 2012 Oct 4.


MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation.

Zubakov D, Boersma AW, Choi Y, van Kuijk PF, Wiemer EA, Kayser M.

Int J Legal Med. 2010 May;124(3):217-26. doi: 10.1007/s00414-009-0402-3. Epub 2010 Feb 10.


Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2).

Burger H, Zoumaro-Djayoon A, Boersma AW, Helleman J, Berns EM, Mathijssen RH, Loos WJ, Wiemer EA.

Br J Pharmacol. 2010 Feb;159(4):898-908. doi: 10.1111/j.1476-5381.2009.00569.x. Epub 2010 Jan 8.


Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer.

Foekens JA, Sieuwerts AM, Smid M, Look MP, de Weerd V, Boersma AW, Klijn JG, Wiemer EA, Martens JW.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13021-6. doi: 10.1073/pnas.0803304105. Epub 2008 Aug 28.


Impaired cisplatin influx in an A2780 mutant cell line: evidence for a putative, cis-configuration-specific, platinum influx transporter.

Helleman J, Burger H, Hamelers IH, Boersma AW, de Kroon AI, Stoter G, Nooter K.

Cancer Biol Ther. 2006 Aug;5(8):943-9. Epub 2006 Aug 2.


Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump.

Burger H, van Tol H, Boersma AW, Brok M, Wiemer EA, Stoter G, Nooter K.

Blood. 2004 Nov 1;104(9):2940-2. Epub 2004 Jul 13.


Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill.

Schenk PW, Brok M, Boersma AW, Brandsma JA, Den Dulk H, Burger H, Stoter G, Brouwer J, Nooter K.

Mol Pharmacol. 2003 Aug;64(2):259-68.


Distinct p53-independent apoptotic cell death signalling pathways in testicular germ cell tumour cell lines.

Burger H, Nooter K, Boersma AW, van Wingerden KE, Looijenga LH, Jochemsen AG, Stoter G.

Int J Cancer. 1999 May 17;81(4):620-8.


Expression of p53, Bcl-2 and Bax in cisplatin-induced apoptosis in testicular germ cell tumour cell lines.

Burger H, Nooter K, Boersma AW, Kortland CJ, Stoter G.

Br J Cancer. 1998 May;77(10):1562-7.


Expression of p53, p21/WAF/CIP, Bcl-2, Bax, Bcl-x, and Bak in radiation-induced apoptosis in testicular germ cell tumor lines.

Burger H, Nooter K, Boersma AW, Kortland CJ, van den Berg AP, Stoter G.

Int J Radiat Oncol Biol Phys. 1998 May 1;41(2):415-24.


Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro.

Ma J, Maliepaard M, Nooter K, Boersma AW, Verweij J, Stoter G, Schellens JH.

Cancer Chemother Pharmacol. 1998;41(4):307-16.


Apoptosis of human seminoma cells upon disruption of their microenvironment.

Olie RA, Boersma AW, Dekker MC, Nooter K, Looijenga LH, Oosterhuis JW.

Br J Cancer. 1996 May;73(9):1031-6.


Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer.

Nooter K, Bosman FT, Burger H, van Wingerden KE, Flens MJ, Scheper RJ, Oostrum RG, Boersma AW, van der Gaast A, Stoter G.

Ann Oncol. 1996 Jan;7(1):75-81.


Effects of cyclosporin A and verapamil on the intracellular daunorubicin accumulation in Chinese hamster ovary cells with increasing levels of drug-resistance.

Silbermann MH, Boersma AW, Janssen AL, Scheper RJ, Herweijer H, Nooter K.

Int J Cancer. 1989 Oct 15;44(4):722-6.


Supplemental Content

Loading ...
Support Center