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Items: 1 to 50 of 160

1.

Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide.

Horwitz ME, Wease S, Blackwell B, Valcarcel D, Frassoni F, Boelens JJ, Nierkens S, Jagasia M, Wagner JE, Kuball J, Koh LP, Majhail NS, Stiff PJ, Hanna R, Hwang WYK, Kurtzberg J, Cilloni D, Freedman LS, Montesinos P, Sanz G.

J Clin Oncol. 2018 Dec 4:JCO1800053. doi: 10.1200/JCO.18.00053. [Epub ahead of print]

PMID:
30523748
2.

Morbidity and Mortality Associated With Respiratory Virus Infections in Allogeneic Hematopoietic Cell Transplant: Too Little Defense or Harmful Immunity?

Versluys AB, Boelens JJ.

Front Microbiol. 2018 Nov 21;9:2795. doi: 10.3389/fmicb.2018.02795. eCollection 2018. Review.

3.

Allogeneic Haematopoietic Cell Transplantation for Epidermolysis Bullosa: the Dutch Experience.

Gostyńska KB, Yenamandra VK, Lindemans C, Duipmans J, Gostyński A, Jonkman MF, Boelens JJ.

Acta Derm Venereol. 2018 Nov 28. doi: 10.2340/00015555-3097. [Epub ahead of print] No abstract available.

4.

Third party, umbilical cord blood derived regulatory T-cells for prevention of graft versus host disease in allogeneic hematopoietic stem cell transplantation: feasibility, safety and immune reconstitution.

Kellner JN, Delemarre EM, Yvon E, Nierkens S, Boelens JJ, McNiece I, Olson A, Nieto Y, Ciurea S, Popat U, Ahmed S, Champlin R, Ramos J, Nishimoto M, Ma H, Ke Z, Thall P, Khoury JD, Negrin R, Andersson B, Parmar S.

Oncotarget. 2018 Nov 2;9(86):35611-35622. doi: 10.18632/oncotarget.26242. eCollection 2018 Nov 2.

5.

Risk factors affecting outcome of unrelated cord blood transplantation for children with familial haemophagocytic lymphohistiocytosis.

Furtado-Silva JM, Paviglianiti A, Ruggeri A, Boelens JJ, Veys P, Ahmari AA, Zecca M, Locatelli F, Michel G, Volt F, Kenzey C, Sedlacek P, Rao K, Lankester A, Gluckman E, Rocha V; Eurocord/ Monacord, Cord Blood Committee of Cellular Therapy, Immunobiology and Inborn Errors Working Parties of the European Blood and Marrow Transplant Group.

Br J Haematol. 2018 Nov 21. doi: 10.1111/bjh.15642. [Epub ahead of print]

PMID:
30460979
6.

Innate Immune Recovery Predicts CD4+ T Cell Reconstitution after Hematopoietic Cell Transplantation.

de Koning C, Langenhorst J, van Kesteren C, Lindemans CA, Huitema ADR, Nierkens S, Boelens JJ.

Biol Blood Marrow Transplant. 2018 Oct 23. pii: S1083-8791(18)30646-3. doi: 10.1016/j.bbmt.2018.10.013. [Epub ahead of print]

PMID:
30359735
7.

Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation.

Langenhorst JB, Dorlo TPC, van Maarseveen EM, Nierkens S, Kuball J, Boelens JJ, van Kesteren C, Huitema ADR.

Clin Pharmacokinet. 2018 Oct 17. doi: 10.1007/s40262-018-0715-9. [Epub ahead of print]

PMID:
30327943
8.

Nedd4-Binding Protein 1 and TNFAIP3-Interacting Protein 1 Control MHC-1 Display in Neuroblastoma.

Spel L, Nieuwenhuis J, Haarsma R, Stickel E, Bleijerveld OB, Altelaar M, Boelens JJ, Brummelkamp TR, Nierkens S, Boes M.

Cancer Res. 2018 Dec 1;78(23):6621-6631. doi: 10.1158/0008-5472.CAN-18-0545. Epub 2018 Sep 13.

PMID:
30213788
9.

Allogeneic Hematopoietic Cell Transplantation in Patients Aged 50Years or Older with Severe Aplastic Anemia.

Rice C, Eikema DJ, Marsh JCW, Knol C, Hebert K, Putter H, Peterson E, Deeg HJ, Halkes S, Pidala J, Anderlini P, Tischer J, Kroger N, McDonald A, Antin JH, Schaap NP, Hallek M, Einsele H, Mathews V, Kapoor N, Boelens JJ, Mufti GJ, Potter V, Pefault de la Tour R, Eapen M, Dufour C.

Biol Blood Marrow Transplant. 2018 Sep 5. pii: S1083-8791(18)30531-7. doi: 10.1016/j.bbmt.2018.08.029. [Epub ahead of print]

PMID:
30194027
10.

Practice pattern changes and improvements in hematopoietic cell transplantation for primary immunodeficiencies.

Marsh RA, Hebert KM, Keesler D, Boelens JJ, Dvorak CC, Eckrich MJ, Kapoor N, Parikh S, Eapen M.

J Allergy Clin Immunol. 2018 Dec;142(6):2004-2007. doi: 10.1016/j.jaci.2018.08.010. Epub 2018 Aug 28. No abstract available.

PMID:
30170121
11.

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.

Matlung HL, Babes L, Zhao XW, van Houdt M, Treffers LW, van Rees DJ, Franke K, Schornagel K, Verkuijlen P, Janssen H, Halonen P, Lieftink C, Beijersbergen RL, Leusen JHW, Boelens JJ, Kuhnle I, van der Werff Ten Bosch J, Seeger K, Rutella S, Pagliara D, Matozaki T, Suzuki E, Menke-van der Houven van Oordt CW, van Bruggen R, Roos D, van Lier RAW, Kuijpers TW, Kubes P, van den Berg TK.

Cell Rep. 2018 Jun 26;23(13):3946-3959.e6. doi: 10.1016/j.celrep.2018.05.082.

12.

Salivary α-Iduronidase Activity as a Potential New Biomarker for the Diagnosis and Monitoring the Effect of Therapy in Mucopolysaccharidosis Type I.

van Doorn J, van den Broek BTA, Geboers AJ, Kuiper GA, Boelens JJ, van Hasselt PM.

Biol Blood Marrow Transplant. 2018 Sep;24(9):1808-1813. doi: 10.1016/j.bbmt.2018.06.001. Epub 2018 Jun 13.

PMID:
29906569
13.

Strategies to Genetically Modulate Dendritic Cells to Potentiate Anti-Tumor Responses in Hematologic Malignancies.

Cornel AM, van Til NP, Boelens JJ, Nierkens S.

Front Immunol. 2018 May 18;9:982. doi: 10.3389/fimmu.2018.00982. eCollection 2018. Review.

14.

Comparison of pediatric allogeneic transplant outcomes using myeloablative busulfan with cyclophosphamide or fludarabine.

Harris AC, Boelens JJ, Ahn KW, Fei M, Abraham A, Artz A, Dvorak C, Frangoul H, Freytes C, Gale RP, Hong S, Lazarus HM, Loren A, Mineishi S, Nishihori T, O'Brien T, Williams K, Pasquini MC, Levine JE.

Blood Adv. 2018 Jun 12;2(11):1198-1206. doi: 10.1182/bloodadvances.2018016956.

15.

Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation.

de Koning C, Gabelich JA, Langenhorst J, Admiraal R, Kuball J, Boelens JJ, Nierkens S.

Blood Adv. 2018 Mar 13;2(5):565-574. doi: 10.1182/bloodadvances.2017015487.

16.

Human herpesvirus 6 viremia affects T-cell reconstitution after allogeneic hematopoietic stem cell transplantation.

de Koning C, Admiraal R, Nierkens S, Boelens JJ.

Blood Adv. 2018 Feb 27;2(4):428-432. doi: 10.1182/bloodadvances.2017012724.

17.

Slowly Progressive Psychiatric Symptoms: Think Metachromatic Leukodystrophy.

van Rappard DF, de Vries ALC, Oostrom KJ, Boelens JJ, Hollak CEM, van der Knaap MS, Wolf NI.

J Am Acad Child Adolesc Psychiatry. 2018 Feb;57(2):74-76. doi: 10.1016/j.jaac.2017.11.017. No abstract available.

PMID:
29413149
18.

Fine-Tuning Antithymocyte Globulin Dosing and Harmonizing Clinical Trial Design.

Boelens JJ, Admiraal R, Kuball J, Nierkens S.

J Clin Oncol. 2018 Apr 10;36(11):1175-1176. doi: 10.1200/JCO.2017.77.1774. Epub 2018 Feb 7. No abstract available.

PMID:
29412785
19.

Diffusion tensor imaging in metachromatic leukodystrophy.

van Rappard DF, Königs M, Steenweg ME, Boelens JJ, Oosterlaan J, van der Knaap MS, Wolf NI, Pouwels PJW.

J Neurol. 2018 Mar;265(3):659-668. doi: 10.1007/s00415-018-8765-3. Epub 2018 Jan 30.

20.

Use of cord blood derived T-cells in cancer immunotherapy: milestones achieved and future perspectives.

Lo Presti V, Nierkens S, Boelens JJ, van Til NP.

Expert Rev Hematol. 2018 Mar;11(3):209-218. doi: 10.1080/17474086.2018.1431119. Epub 2018 Feb 1.

PMID:
29359983
21.

Early and late outcomes after cord blood transplantation for pediatric patients with inherited leukodystrophies.

van den Broek BTA, Page K, Paviglianiti A, Hol J, Allewelt H, Volt F, Michel G, Diaz MA, Bordon V, O'Brien T, Shaw PJ, Kenzey C, Al-Seraihy A, van Hasselt PM, Gennery AR, Gluckman E, Rocha V, Ruggeri A, Kurtzberg J, Boelens JJ.

Blood Adv. 2018 Jan 4;2(1):49-60. doi: 10.1182/bloodadvances.2017010645. eCollection 2018 Jan 9.

22.

Quality of life of Hurler syndrome patients after successful hematopoietic stem cell transplantation.

Aldenhoven M, van den Broek BTA, Wynn RF, O'Meara A, Veys P, Rovelli A, Jones SA, Parini R, van Hasselt PM, Renard M, Bordon V, de Koning TJ, Boelens JJ.

Blood Adv. 2017 Nov 7;1(24):2236-2242. doi: 10.1182/bloodadvances.2017011387. eCollection 2017 Nov 14. Erratum in: Blood Adv. 2017 Dec 07;1(26):2535.

23.

Low Body Mass Index Is Associated with Increased Risk of Acute GVHD after Umbilical Cord Blood Transplantation in Children and Young Adults with Acute Leukemia: A Study on Behalf of Eurocord and the EBMT Pediatric Disease Working Party.

Paviglianiti A, Dalle JH, Ayas M, Boelens JJ, Volt F, Iori AP, de Souza MP, Diaz MA, Michel G, Locatelli F, Jubert C, Yakoub-Agha I, Bittencourt H, Bertrand Y, Kenzey C, Tozatto Maio K, Hayashi H, Rocha V, Bader P, Gluckman E, Ruggeri A.

Biol Blood Marrow Transplant. 2018 Apr;24(4):799-805. doi: 10.1016/j.bbmt.2017.12.790. Epub 2017 Dec 27.

PMID:
29288817
24.

GSTA1 diplotypes affect busulfan clearance and toxicity in children undergoing allogeneic hematopoietic stem cell transplantation: a multicenter study.

Ansari M, Curtis PH, Uppugunduri CRS, Rezgui MA, Nava T, Mlakar V, Lesne L, Théoret Y, Chalandon Y, Dupuis LL, Schechter T, Bartelink IH, Boelens JJ, Bredius R, Dalle JH, Azarnoush S, Sedlacek P, Lewis V, Champagne M, Peters C, Bittencourt H, Krajinovic M.

Oncotarget. 2017 Aug 27;8(53):90852-90867. doi: 10.18632/oncotarget.20310. eCollection 2017 Oct 31.

25.

Intravenous Busulfan Compared with Total Body Irradiation Pretransplant Conditioning for Adults with Acute Lymphoblastic Leukemia.

Kebriaei P, Anasetti C, Zhang MJ, Wang HL, Aldoss I, de Lima M, Khoury HJ, Sandmaier BM, Horowitz MM, Artz A, Bejanyan N, Ciurea S, Lazarus HM, Gale RP, Litzow M, Bredeson C, Seftel MD, Pulsipher MA, Boelens JJ, Alvarnas J, Champlin R, Forman S, Pullarkat V, Weisdorf D, Marks DI; Acute Leukemia Committee of the CIBMTR.

Biol Blood Marrow Transplant. 2018 Apr;24(4):726-733. doi: 10.1016/j.bbmt.2017.11.025. Epub 2017 Dec 25.

PMID:
29197676
26.

Antithymocyte Globulin: Steps Toward Individualized Dosing.

Admiraal R, Boelens JJ.

Biol Blood Marrow Transplant. 2018 Mar;24(3):633-634. doi: 10.1016/j.bbmt.2017.11.020. Epub 2017 Nov 28. No abstract available.

PMID:
29196073
27.

Quantitative MR spectroscopic imaging in metachromatic leukodystrophy: value for prognosis and treatment.

van Rappard DF, Klauser A, Steenweg ME, Boelens JJ, Bugiani M, van der Knaap MS, Wolf NI, Pouwels PJW.

J Neurol Neurosurg Psychiatry. 2018 Jan;89(1):105-111. doi: 10.1136/jnnp-2017-316364. Epub 2017 Sep 9.

PMID:
28889092
28.

Relationship between Mixed Donor-Recipient Chimerism and Disease Recurrence after Hematopoietic Cell Transplantation for Sickle Cell Disease.

Abraham A, Hsieh M, Eapen M, Fitzhugh C, Carreras J, Keesler D, Guilcher G, Kamani N, Walters MC, Boelens JJ, Tisdale J, Shenoy S; National Institutes of Health; Center for International Blood and Marrow Transplant Research.

Biol Blood Marrow Transplant. 2017 Dec;23(12):2178-2183. doi: 10.1016/j.bbmt.2017.08.038. Epub 2017 Sep 4.

29.

In vivo and in vitro palatability testing of a new paediatric formulation of valaciclovir.

Bastiaans DET, Immohr LI, Zeinstra GG, Strik-Albers R, Pein-Hackelbusch M, van der Flier M, de Haan AFJ, Boelens JJ, Lankester AC, Burger DM, Warris A.

Br J Clin Pharmacol. 2017 Dec;83(12):2789-2797. doi: 10.1111/bcp.13396. Epub 2017 Sep 20.

30.

Infection with a respiratory virus before hematopoietic cell transplantation is associated with alloimmune-mediated lung syndromes.

Versluys B, Bierings M, Murk JL, Wolfs T, Lindemans C, Vd Ent K, Boelens JJ.

J Allergy Clin Immunol. 2018 Feb;141(2):697-703.e8. doi: 10.1016/j.jaci.2017.03.055. Epub 2017 Jul 15.

PMID:
28716387
31.

Rabbit anti-human-T-lymphocyte globulin-less is more.

Boelens JJ.

Lancet Oncol. 2017 Aug;18(8):996-997. doi: 10.1016/S1470-2045(17)30443-6. Epub 2017 Jul 10. No abstract available.

PMID:
28705453
32.

Incomplete biomarker response in mucopolysaccharidosis type I after successful hematopoietic cell transplantation.

Kuiper GA, van Hasselt PM, Boelens JJ, Wijburg FA, Langereis EJ.

Mol Genet Metab. 2017 Sep;122(1-2):86-91. doi: 10.1016/j.ymgme.2017.05.009. Epub 2017 May 18.

PMID:
28684085
33.

Allele-level HLA matching for umbilical cord blood transplantation for non-malignant diseases in children: a retrospective analysis.

Eapen M, Wang T, Veys PA, Boelens JJ, St Martin A, Spellman S, Bonfim CS, Brady C, Cant AJ, Dalle JH, Davies SM, Freeman J, Hsu KC, Fleischhauer K, Kenzey C, Kurtzberg J, Michel G, Orchard PJ, Paviglianiti A, Rocha V, Veneris MR, Volt F, Wynn R, Lee SJ, Horowitz MM, Gluckman E, Ruggeri A.

Lancet Haematol. 2017 Jul;4(7):e325-e333. doi: 10.1016/S2352-3026(17)30104-7. Epub 2017 Jun 13.

34.

Immune reconstitution and outcomes after conditioning with anti-thymocyte-globulin in unrelated cord blood transplantation; the good, the bad, and the ugly.

de Koning C, Admiraal R, Nierkens S, Boelens JJ.

Stem Cell Investig. 2017 May 16;4:38. doi: 10.21037/sci.2017.05.02. eCollection 2017. Review.

35.

Simultaneous quantification of busulfan, clofarabine and F-ARA-A using isotope labelled standards and standard addition in plasma by LC-MS/MS for exposure monitoring in hematopoietic cell transplantation conditioning.

Punt AM, Langenhorst JB, Egas AC, Boelens JJ, van Kesteren C, van Maarseveen EM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jun 15;1055-1056:81-85. doi: 10.1016/j.jchromb.2017.04.025. Epub 2017 Apr 15.

36.

Viral reactivations and associated outcomes in the context of immune reconstitution after pediatric hematopoietic cell transplantation.

Admiraal R, de Koning CCH, Lindemans CA, Bierings MB, Wensing AMJ, Versluys AB, Wolfs TFW, Nierkens S, Boelens JJ.

J Allergy Clin Immunol. 2017 Dec;140(6):1643-1650.e9. doi: 10.1016/j.jaci.2016.12.992. Epub 2017 Apr 7.

PMID:
28392330
37.

Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia.

Kekre N, Zhang Y, Zhang MJ, Carreras J, Ahmed P, Anderlini P, Atta EH, Ayas M, Boelens JJ, Bonfim C, Deeg HJ, Kapoor N, Lee JW, Nakamura R, Pulsipher MA, Eapen M, Antin JH.

Haematologica. 2017 Jul;102(7):1291-1298. doi: 10.3324/haematol.2017.164459. Epub 2017 Mar 24.

38.

Association between anti-thymocyte globulin exposure and survival outcomes in adult unrelated haemopoietic cell transplantation: a multicentre, retrospective, pharmacodynamic cohort analysis.

Admiraal R, Nierkens S, de Witte MA, Petersen EJ, Fleurke GJ, Verrest L, Belitser SV, Bredius RGM, Raymakers RAP, Knibbe CAJ, Minnema MC, van Kesteren C, Kuball J, Boelens JJ.

Lancet Haematol. 2017 Apr;4(4):e183-e191. doi: 10.1016/S2352-3026(17)30029-7. Epub 2017 Mar 16. Erratum in: Lancet Haematol. 2017 May;4(5):e201.

PMID:
28330607
39.

Busulfan after HSCT in children and young adults - Authors' reply.

Bartelink IH, Lalmohamed A, Long-Boyle JR, Boelens JJ.

Lancet Haematol. 2017 Mar;4(3):e103-e104. doi: 10.1016/S2352-3026(17)30018-2. No abstract available.

PMID:
28257750
40.

A risk factor analysis of outcomes after unrelated cord blood transplantation for children with Wiskott-Aldrich syndrome.

Shekhovtsova Z, Bonfim C, Ruggeri A, Nichele S, Page K, AlSeraihy A, Barriga F, de Toledo Codina JS, Veys P, Boelens JJ, Mellgren K, Bittencourt H, O'Brien T, Shaw PJ, Chybicka A, Volt F, Giannotti F, Gluckman E, Kurtzberg J, Gennery AR, Rocha V; Eurocord, Cord Blood Committee of Cellular Therapy and Immunobiology Working Party of the EBMT, Federal University of Parana, Duke University Medical Center and Inborn Errors Working Party of the EBMT.

Haematologica. 2017 Jun;102(6):1112-1119. doi: 10.3324/haematol.2016.158808. Epub 2017 Mar 2.

41.

Haematopoietic stem cell transplantation for autoimmune diseases.

Swart JF, Delemarre EM, van Wijk F, Boelens JJ, Kuball J, van Laar JM, Wulffraat NM.

Nat Rev Rheumatol. 2017 Apr;13(4):244-256. doi: 10.1038/nrrheum.2017.7. Epub 2017 Feb 23. Review.

PMID:
28228650
42.

Excellent T-cell reconstitution and survival depend on low ATG exposure after pediatric cord blood transplantation.

Admiraal R, Lindemans CA, van Kesteren C, Bierings MB, Versluijs AB, Nierkens S, Boelens JJ.

Blood. 2016 Dec 8;128(23):2734-2741. Epub 2016 Oct 4.

43.

Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.

Bartelink IH, Lalmohamed A, van Reij EM, Dvorak CC, Savic RM, Zwaveling J, Bredius RG, Egberts AC, Bierings M, Kletzel M, Shaw PJ, Nath CE, Hempel G, Ansari M, Krajinovic M, Théorêt Y, Duval M, Keizer RJ, Bittencourt H, Hassan M, Güngör T, Wynn RF, Veys P, Cuvelier GD, Marktel S, Chiesa R, Cowan MJ, Slatter MA, Stricherz MK, Jennissen C, Long-Boyle JR, Boelens JJ.

Lancet Haematol. 2016 Nov;3(11):e526-e536. doi: 10.1016/S2352-3026(16)30114-4. Epub 2016 Oct 13.

44.

Strategies before, during, and after hematopoietic cell transplantation to improve T-cell immune reconstitution.

de Koning C, Nierkens S, Boelens JJ.

Blood. 2016 Dec 8;128(23):2607-2615. Epub 2016 Oct 3. Review.

45.

Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease: Final Results From the International Compassionate-Use Program.

Corbacioglu S, Carreras E, Mohty M, Pagliuca A, Boelens JJ, Damaj G, Iacobelli M, Niederwieser D, Olavarría E, Suarez F, Ruutu T, Verdonck L, Hume R, Nejadnik B, Lai C, Finetto G, Richardson P.

Biol Blood Marrow Transplant. 2016 Oct;22(10):1874-1882. doi: 10.1016/j.bbmt.2016.07.001. Epub 2016 Jul 7.

46.

The power of cord blood cells.

Boelens JJ.

Blood. 2016 Jun 30;127(26):3302-3. doi: 10.1182/blood-2016-04-713065. No abstract available.

47.

Neurodevelopmental Outcome after Hematopoietic Cell Transplantation in Inborn Errors of Metabolism: Current Considerations and Future Perspectives.

Boelens JJ, van Hasselt PM.

Neuropediatrics. 2016 Oct;47(5):285-92. doi: 10.1055/s-0036-1584602. Epub 2016 Jun 16. Review.

PMID:
27308871
48.

Gallbladder and the risk of polyps and carcinoma in metachromatic leukodystrophy.

van Rappard DF, Bugiani M, Boelens JJ, van der Steeg AF, Daams F, de Meij TG, van Doorn MM, van Hasselt PM, Gouma DJ, Verbeke JI, Hollak CE, van Hecke W, Salomons GS, van der Knaap MS, Wolf NI.

Neurology. 2016 Jul 5;87(1):103-11. doi: 10.1212/WNL.0000000000002811. Epub 2016 Jun 3.

PMID:
27261095
49.

Antithymocyte globulin: Importance of good clinical pharmacological practice.

Admiraal R, van Kesteren C, Nierkens S, Boelens JJ.

J Allergy Clin Immunol. 2016 Aug;138(2):633. doi: 10.1016/j.jaci.2016.02.036. Epub 2016 May 20. No abstract available.

PMID:
27212085
50.

Leukemia-free survival in myeloid leukemia, but not in lymphoid leukemia, is predicted by early CD4+ reconstitution following unrelated cord blood transplantation in children: a multicenter retrospective cohort analysis.

Admiraal R, Chiesa R, Lindemans CA, Nierkens S, Bierings MB, Versluijs AB, Hiwarkar P, Furtado Silva JM, Veys P, Boelens JJ.

Bone Marrow Transplant. 2016 Oct;51(10):1376-1378. doi: 10.1038/bmt.2016.116. Epub 2016 May 9. No abstract available.

PMID:
27159172

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