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Items: 9

1.

AMPK directly activates mTORC2 to promote cell survival during acute energetic stress.

Kazyken D, Magnuson B, Bodur C, Acosta-Jaquez HA, Zhang D, Tong X, Barnes TM, Steinl GK, Patterson NE, Altheim CH, Sharma N, Inoki K, Cartee GD, Bridges D, Yin L, Riddle SM, Fingar DC.

Sci Signal. 2019 Jun 11;12(585). pii: eaav3249. doi: 10.1126/scisignal.aav3249.

PMID:
31186373
2.

The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists.

Bodur C, Kazyken D, Huang K, Ekim Ustunel B, Siroky KA, Tooley AS, Gonzalez IE, Foley DH, Acosta-Jaquez HA, Barnes TM, Steinl GK, Cho KW, Lumeng CN, Riddle SM, Myers MG Jr, Fingar DC.

EMBO J. 2018 Jan 4;37(1):19-38. doi: 10.15252/embj.201696164. Epub 2017 Nov 17.

3.

AMP-activated protein kinase couples 3-bromopyruvate-induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins.

Bodur C, Karakas B, Timucin AC, Tezil T, Basaga H.

Mol Carcinog. 2016 Nov;55(11):1584-1597. doi: 10.1002/mc.22411. Epub 2015 Sep 16.

PMID:
26373689
4.

SIRT1 contributes to aldose reductase expression through modulating NFAT5 under osmotic stress: In vitro and in silico insights.

Timucin AC, Bodur C, Basaga H.

Cell Signal. 2015 Nov;27(11):2160-72. doi: 10.1016/j.cellsig.2015.08.013. Epub 2015 Aug 20.

PMID:
26297866
5.

Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling.

Bodur C, Kutuk O, Karsli-Uzunbas G, Isimjan TT, Harrison P, Basaga H.

PLoS One. 2013;8(2):e56369. doi: 10.1371/journal.pone.0056369. Epub 2013 Feb 18.

6.

Bcl-2 inhibitors: emerging drugs in cancer therapy.

Bodur C, Basaga H.

Curr Med Chem. 2012;19(12):1804-20. Review.

PMID:
22414090
7.

IKK-β mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death.

Tezil T, Bodur C, Kutuk O, Basaga H.

Cell Signal. 2012 Jun;24(6):1361-8. doi: 10.1016/j.cellsig.2012.01.012. Epub 2012 Jan 31.

PMID:
22313691
8.

Inactivation of Bcl-2 through IκB kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE).

Bodur C, Kutuk O, Tezil T, Basaga H.

J Cell Physiol. 2012 Nov;227(11):3556-65. doi: 10.1002/jcp.24057.

PMID:
22262057
9.

Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells.

Arisan ED, Kutuk O, Tezil T, Bodur C, Telci D, Basaga H.

Breast Cancer Res Treat. 2010 Jan;119(2):271-81. doi: 10.1007/s10549-009-0343-z. Epub 2009 Feb 24.

PMID:
19238538

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