Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 420

1.

Single-molecule DNA-mapping and whole-genome sequencing of individual cells.

Marie R, Pedersen JN, Bærlocher L, Koprowska K, Pødenphant M, Sabatel C, Zalkovskij M, Mironov A, Bilenberg B, Ashley N, Flyvbjerg H, Bodmer WF, Kristensen A, Mir KU.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11192-11197. doi: 10.1073/pnas.1804194115. Epub 2018 Oct 15.

2.

Cellular polarity modulates drug resistance in primary colorectal cancers via orientation of the multidrug resistance protein ABCB1.

Ashley N, Ouaret D, Bodmer WF.

J Pathol. 2019 Mar;247(3):293-304. doi: 10.1002/path.5179. Epub 2019 Jan 16.

3.

Genetics of the human face: Identification of large-effect single gene variants.

Crouch DJM, Winney B, Koppen WP, Christmas WJ, Hutnik K, Day T, Meena D, Boumertit A, Hysi P, Nessa A, Spector TD, Kittler J, Bodmer WF.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E676-E685. doi: 10.1073/pnas.1708207114. Epub 2018 Jan 4.

4.

A Haldane perspective from a Fisher student.

Bodmer WF.

J Genet. 2017 Nov;96(5):743-746. No abstract available.

5.

Stromal uptake and transmission of acid is a pathway for venting cancer cell-generated acid.

Hulikova A, Black N, Hsia LT, Wilding J, Bodmer WF, Swietach P.

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5344-53. doi: 10.1073/pnas.1610954113. Epub 2016 Aug 19.

6.

Paul Ichiro Terasaki (1929-2016): Inventor of the microcytotoxicity assay and pioneer tissue typer.

Bodmer WF.

HLA. 2016 May;87(5):333-7. doi: 10.1111/tan.12809. No abstract available.

PMID:
27101942
7.

Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers.

Hsia LT, Ashley N, Ouaret D, Wang LM, Wilding J, Bodmer WF.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):E2162-71. doi: 10.1073/pnas.1603534113. Epub 2016 Mar 28.

8.

The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiation.

Jones MF, Hara T, Francis P, Li XL, Bilke S, Zhu Y, Pineda M, Subramanian M, Bodmer WF, Lal A.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1550-8. doi: 10.1073/pnas.1503370112. Epub 2015 Mar 16.

9.

Molecular genetics research in sub-Saharan Africa: how can the international community help?

Bekele E, Bodmer WF, Bradman N, Craig IW, Makani J, Povey S, Rotimi C.

Hugo J. 2014 Dec;8(1):2. doi: 10.1186/s11568-014-0002-2. Epub 2014 Sep 17.

10.

Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling.

Gao S, Bajrami I, Verrill C, Kigozi A, Ouaret D, Aleksic T, Asher R, Han C, Allen P, Bailey D, Feller S, Kashima T, Athanasou N, Blay JY, Schmitz S, Machiels JP, Upile N, Jones TM, Thalmann G, Ashraf SQ, Wilding JL, Bodmer WF, Middleton MR, Ashworth A, Lord CJ, Macaulay VM.

Cancer Res. 2014 Oct 15;74(20):5866-77. doi: 10.1158/0008-5472.CAN-14-0806. Epub 2014 Aug 28.

11.

Rapidly derived colorectal cancer cultures recapitulate parental cancer characteristics and enable personalized therapeutic assays.

Ashley N, Jones M, Ouaret D, Wilding J, Bodmer WF.

J Pathol. 2014 Sep;234(1):34-45. doi: 10.1002/path.4371. Epub 2014 Jul 7.

PMID:
24797403
12.

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.

Mouradov D, Sloggett C, Jorissen RN, Love CG, Li S, Burgess AW, Arango D, Strausberg RL, Buchanan D, Wormald S, O'Connor L, Wilding JL, Bicknell D, Tomlinson IP, Bodmer WF, Mariadason JM, Sieber OM.

Cancer Res. 2014 Jun 15;74(12):3238-47. doi: 10.1158/0008-5472.CAN-14-0013. Epub 2014 Apr 22.

13.

Cancer cell lines for drug discovery and development.

Wilding JL, Bodmer WF.

Cancer Res. 2014 May 1;74(9):2377-84. doi: 10.1158/0008-5472.CAN-13-2971. Epub 2014 Apr 9. Review.

14.

Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors.

Ashley N, Yeung TM, Bodmer WF.

Cancer Res. 2013 Sep 15;73(18):5798-809. doi: 10.1158/0008-5472.CAN-13-0454. Epub 2013 Jul 18.

15.

Myofibroblast activation in colorectal cancer lymph node metastases.

Yeung TM, Buskens C, Wang LM, Mortensen NJ, Bodmer WF.

Br J Cancer. 2013 May 28;108(10):2106-15. doi: 10.1038/bjc.2013.209. Epub 2013 May 7.

16.

Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel.

Ashraf SQ, Nicholls AM, Wilding JL, Ntouroupi TG, Mortensen NJ, Bodmer WF.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21046-51. doi: 10.1073/pnas.1218750110. Epub 2012 Dec 3.

17.

Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer.

Lefevre JH, Bonilla C, Colas C, Winney B, Johnstone E, Tonks S, Day T, Hutnik K, Boumertit A, Soubrier F, Midgley R, Kerr D, Parc Y, Bodmer WF.

J Hum Genet. 2012 Nov 26;57(11):709-716. doi: 10.1038/jhg.2012.99. Epub 2012 Aug 9.

18.

Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells.

Yeung TM, Gandhi SC, Bodmer WF.

Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4382-7. doi: 10.1073/pnas.1014519107. Epub 2011 Feb 23.

19.

Cyclin D1 rare variants in UK multiple adenoma and early-onset colorectal cancer patients.

Bonilla C, Lefèvre JH, Winney B, Johnstone E, Tonks S, Colas C, Day T, Hutnik K, Boumertit A, Midgley R, Kerr D, Parc Y, Bodmer WF.

J Hum Genet. 2011 Jan;56(1):58-63. doi: 10.1038/jhg.2010.144. Epub 2010 Nov 25.

20.

Replication error deficient and proficient colorectal cancer gene expression differences caused by 3'UTR polyT sequence deletions.

Wilding JL, McGowan S, Liu Y, Bodmer WF.

Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21058-63. doi: 10.1073/pnas.1015604107. Epub 2010 Nov 19.

21.

On the proportion of cancer stem cells in a tumour.

Johnston MD, Maini PK, Jonathan Chapman S, Edwards CM, Bodmer WF.

J Theor Biol. 2010 Oct 21;266(4):708-11. doi: 10.1016/j.jtbi.2010.07.031. Epub 2010 Aug 3.

PMID:
20678505
22.

5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.

Bracht K, Nicholls AM, Liu Y, Bodmer WF.

Br J Cancer. 2010 Jul 27;103(3):340-6. doi: 10.1038/sj.bjc.6605780. Epub 2010 Jul 6.

23.

Failure to validate association between 12p13 variants and ischemic stroke.

International Stroke Genetics Consortium; Wellcome Trust Case-Control Consortium 2.

N Engl J Med. 2010 Apr 22;362(16):1547-50. doi: 10.1056/NEJMc0910050. No abstract available.

24.

Comprehensive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition.

Carvajal-Carmona LG, Churchman M, Bonilla C, Walther A, Lefèvre JH, Kerr D, Dunlop M, Houlston R, Bodmer WF, Tomlinson I.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7858-62. doi: 10.1073/pnas.1002816107. Epub 2010 Apr 5.

25.

Nomenclature for factors of the HLA system, 2010.

Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Fernández-Viña M, Geraghty DE, Holdsworth R, Hurley CK, Lau M, Lee KW, Mach B, Maiers M, Mayr WR, Müller CR, Parham P, Petersdorf EW, Sasazuki T, Strominger JL, Svejgaard A, Terasaki PI, Tiercy JM, Trowsdale J.

Tissue Antigens. 2010 Apr;75(4):291-455. doi: 10.1111/j.1399-0039.2010.01466.x. Review. No abstract available.

26.

Linkage disequilibrium and age of HLA region SNPs in relation to classic HLA gene alleles within Europe.

Evseeva I, Nicodemus KK, Bonilla C, Tonks S, Bodmer WF.

Eur J Hum Genet. 2010 Aug;18(8):924-32. doi: 10.1038/ejhg.2010.32. Epub 2010 Mar 31.

27.

An update to HLA nomenclature, 2010.

Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Fernández-Viña M, Geraghty DE, Holdsworth R, Hurley CK, Lau M, Lee KW, Mach B, Maiers M, Mayr WR, Müller CR, Parham P, Petersdorf EW, Sasazuki T, Strominger JL, Svejgaard A, Terasaki PI, Tiercy JM, Trowsdale J.

Bone Marrow Transplant. 2010 May;45(5):846-8. doi: 10.1038/bmt.2010.79. Epub 2010 Mar 29.

PMID:
20348972
28.

Commentary: Connections between genetics and statistics: a commentary on Fisher's 1951 Bateson lecture--'Statistical Methods in Genetics'.

Bodmer WF.

Int J Epidemiol. 2010 Apr;39(2):340-4. doi: 10.1093/ije/dyq014. Epub 2010 Feb 22. No abstract available.

PMID:
20176586
29.

Cancer stem cells from colorectal cancer-derived cell lines.

Yeung TM, Gandhi SC, Wilding JL, Muschel R, Bodmer WF.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3722-7. doi: 10.1073/pnas.0915135107. Epub 2010 Feb 2.

30.

Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis.

Ashraf SQ, Umana P, Mössner E, Ntouroupi T, Brünker P, Schmidt C, Wilding JL, Mortensen NJ, Bodmer WF.

Br J Cancer. 2009 Nov 17;101(10):1758-68. doi: 10.1038/sj.bjc.6605355.

31.

Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1.

Chan CW, Wong NA, Liu Y, Bicknell D, Turley H, Hollins L, Miller CJ, Wilding JL, Bodmer WF.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1936-41. doi: 10.1073/pnas.0812904106. Epub 2009 Feb 2.

32.

Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope.

Ntouroupi TG, Ashraf SQ, McGregor SB, Turney BW, Seppo A, Kim Y, Wang X, Kilpatrick MW, Tsipouras P, Tafas T, Bodmer WF.

Br J Cancer. 2008 Sep 2;99(5):789-95. doi: 10.1038/sj.bjc.6604545.

33.

Mutations in the AXIN1 gene in advanced prostate cancer.

Yardy GW, Bicknell DC, Wilding JL, Bartlett S, Liu Y, Winney B, Turner GD, Brewster SF, Bodmer WF.

Eur Urol. 2009 Sep;56(3):486-94. doi: 10.1016/j.eururo.2008.05.029. Epub 2008 May 23.

PMID:
18514389
34.

Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen.

Conaghan P, Ashraf S, Tytherleigh M, Wilding J, Tchilian E, Bicknell D, Mortensen NJ, Bodmer W.

Br J Cancer. 2008 Apr 8;98(7):1217-25. doi: 10.1038/sj.bjc.6604289. Epub 2008 Mar 18.

35.

Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells.

Emaduddin M, Bicknell DC, Bodmer WF, Feller SM.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2358-62. doi: 10.1073/pnas.0712176105. Epub 2008 Feb 7.

36.

Examples of mathematical modeling: tales from the crypt.

Johnston MD, Edwards CM, Bodmer WF, Maini PK, Chapman SJ.

Cell Cycle. 2007 Sep 1;6(17):2106-12. Epub 2007 Jun 27.

37.

Multigene amplification and massively parallel sequencing for cancer mutation discovery.

Dahl F, Stenberg J, Fredriksson S, Welch K, Zhang M, Nilsson M, Bicknell D, Bodmer WF, Davis RW, Ji H.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9387-92. Epub 2007 May 17.

38.

Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer.

Johnston MD, Edwards CM, Bodmer WF, Maini PK, Chapman SJ.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4008-13. Epub 2007 Feb 28.

39.

Cancer genetics: colorectal cancer as a model.

Bodmer WF.

J Hum Genet. 2006;51(5):391-6. Epub 2006 Apr 5. Review.

40.

EpCAM and gpA33 are markers of Barrett's metaplasia.

Wong NA, Warren BF, Piris J, Maynard N, Marshall R, Bodmer WF.

J Clin Pathol. 2006 Mar;59(3):260-3. Epub 2006 Feb 10.

41.

Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines.

Liu Y, Bodmer WF.

Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):976-81. Epub 2006 Jan 17.

42.

A mutated HLA-A*0101 allele in the colorectal cell line HCA-7.

Bicknell DC, Bodmer WF.

Tissue Antigens. 2005 Sep;66(3):231-7.

PMID:
16101834
43.

Nomenclature for Factors of the HLA System, 2004.

Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Hurley CK, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI, Trowsdale J.

Hum Immunol. 2005 May;66(5):571-636. Epub 2005 Mar 3. No abstract available.

PMID:
15935895
44.

CDX1 is an important molecular mediator of Barrett's metaplasia.

Wong NA, Wilding J, Bartlett S, Liu Y, Warren BF, Piris J, Maynard N, Marshall R, Bodmer WF.

Proc Natl Acad Sci U S A. 2005 May 24;102(21):7565-70. Epub 2005 May 13.

45.

Immune responses in advanced colorectal cancer following repeated intradermal vaccination with the anti-CEA murine monoclonal antibody, PR1A3: results of a phase I study.

Zbar AP, Thomas H, Wilkinson RW, Wadhwa M, Syrigos KN, Ross EL, Dilger P, Allen-Mersh TG, Kmiot WA, Epenetos AA, Snary D, Bodmer WF.

Int J Colorectal Dis. 2005 Sep;20(5):403-14. Epub 2005 Apr 30.

PMID:
15864608
46.

Preclinical application of radioimmunoguided surgery using anti-carcinoembryonic antigen biparatopic antibody in the colon cancer.

Kim JC, Roh SA, Koo KH, Cho YK, Kim HC, Yu CS, Oh SJ, Ryu JS, Bicknell DC, Bodmer WF.

Eur Surg Res. 2005 Jan-Feb;37(1):36-44.

PMID:
15818040
47.

Nomenclature for factors of the HLA system, 2004.

Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Hurley CK, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI, Trowsdale J.

Tissue Antigens. 2005 Apr;65(4):301-69. No abstract available.

PMID:
15787720
48.

Nomenclature for factors of the HLA system, 2004.

Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Hurley CK, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI, Trowsdale J.

Int J Immunogenet. 2005 Apr;32(2):107-59. No abstract available.

PMID:
15787643
49.

Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model.

Fearnhead NS, Winney B, Bodmer WF.

Cell Cycle. 2005 Apr;4(4):521-5. Epub 2005 Apr 7. Review.

PMID:
15753653
50.

Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas.

Fearnhead NS, Wilding JL, Winney B, Tonks S, Bartlett S, Bicknell DC, Tomlinson IP, Mortensen NJ, Bodmer WF.

Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15992-7. Epub 2004 Nov 1.

Supplemental Content

Loading ...
Support Center