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Items: 1 to 50 of 510

1.

Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis.

Queck A, Bode H, Uschner FE, Brol MJ, Graf C, Schulz M, Jansen C, Praktiknjo M, Schierwagen R, Klein S, Trautwein C, Wasmuth HE, Berres ML, Trebicka J, Lehmann J.

Front Immunol. 2020 Mar 11;11:354. doi: 10.3389/fimmu.2020.00354. eCollection 2020.

2.

A New Docking Domain Type in the Peptide-Antimicrobial-Xenorhabdus Peptide Producing Nonribosomal Peptide Synthetase from Xenorhabdus bovienii.

Watzel J, Hacker C, Duchardt-Ferner E, Bode HB, Wöhnert J.

ACS Chem Biol. 2020 Mar 25. doi: 10.1021/acschembio.9b01022. [Epub ahead of print]

PMID:
32167274
3.

Engineering bacterial symbionts of nematodes improves biocontrol potential of the western corn rootworm.

Machado RAR, Thönen L, Arce CCM, Theepan V, Prada F, Wüthrich D, Robert CAM, Vogiatzaki E, Shi YM, Schaeren OP, Notter M, Bruggmann R, Hapfelmeier S, Bode HB, Erb M.

Nat Biotechnol. 2020 Feb 17. doi: 10.1038/s41587-020-0419-1. [Epub ahead of print]

PMID:
32066956
4.

Treatment with and without stabilizing lumbar spinal orthosis after one- or two-level spondylodesis: A randomized controlled trial.

Rommelspacher Y, Bode H, Ziob J, Struwe C, Kasapovic A, Walter SG, Schildberg FA, Bornemann R, Wirtz DC, Pflugmacher R.

Technol Health Care. 2020 Jan 7. doi: 10.3233/THC-191820. [Epub ahead of print]

PMID:
31958099
5.

Phenylethylamides derived from bacterial secondary metabolites specifically inhibit an insect serotonin receptor.

Hasan A, Yeom HS, Ryu J, Bode HB, Kim Y.

Sci Rep. 2019 Dec 30;9(1):20358. doi: 10.1038/s41598-019-56892-z.

6.

Nematode-Associated Bacteria: Production of Antimicrobial Agent as a Presumptive Nominee for Curing Endodontic Infections Caused by Enterococcus faecalis.

Donmez Ozkan H, Cimen H, Ulug D, Wenski S, Yigit Ozer S, Telli M, Aydin N, Bode HB, Hazir S.

Front Microbiol. 2019 Nov 22;10:2672. doi: 10.3389/fmicb.2019.02672. eCollection 2019.

7.

Phototemtide A, a Cyclic Lipopeptide Heterologously Expressed from Photorhabdus temperata Meg1, Shows Selective Antiprotozoal Activity.

Zhao L, Vo TD, Kaiser M, Bode HB.

Chembiochem. 2019 Dec 9. doi: 10.1002/cbic.201900665. [Epub ahead of print]

PMID:
31814269
8.

Efficient nonenzymatic cyclization and domain shuffling drive pyrrolopyrazine diversity from truncated variants of a fungal NRPS.

Berry D, Mace W, Grage K, Wesche F, Gore S, Schardl CL, Young CA, Dijkwel PP, Leuchtmann A, Bode HB, Scott B.

Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25614-25623. doi: 10.1073/pnas.1913080116. Epub 2019 Dec 4.

9.

Structure, Biosynthesis, and Bioactivity of Photoditritide from Photorhabdus temperata Meg1.

Zhao L, Awori RM, Kaiser M, Groß J, Opatz T, Bode HB.

J Nat Prod. 2019 Dec 27;82(12):3499-3503. doi: 10.1021/acs.jnatprod.9b00932. Epub 2019 Dec 4.

PMID:
31799840
10.

New Vocabulary for Bacterial Communication.

Tobias NJ, Brehm J, Kresovic D, Brameyer S, Bode HB, Heermann R.

Chembiochem. 2020 Mar 16;21(6):759-768. doi: 10.1002/cbic.201900580. Epub 2019 Dec 16. Review.

PMID:
31709676
11.

Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing.

Bode E, Heinrich AK, Hirschmann M, Abebew D, Shi YN, Vo TD, Wesche F, Shi YM, Grün P, Simonyi S, Keller N, Engel Y, Wenski S, Bennet R, Beyer S, Bischoff I, Buaya A, Brandt S, Cakmak I, Çimen H, Eckstein S, Frank D, Fürst R, Gand M, Geisslinger G, Hazir S, Henke M, Heermann R, Lecaudey V, Schäfer W, Schiffmann S, Schüffler A, Schwenk R, Skaljac M, Thines E, Thines M, Ulshöfer T, Vilcinskas A, Wichelhaus TA, Bode HB.

Angew Chem Int Ed Engl. 2019 Dec 19;58(52):18957-18963. doi: 10.1002/anie.201910563. Epub 2019 Dec 12.

12.

Methylphenidate in children with monogenic obesity due to LEPR or MC4R deficiency improves feeling of satiety and reduces BMI-SDS-A case series.

Brandt S, von Schnurbein J, Lennerz B, Kohlsdorf K, Vollbach H, Denzer C, Bode H, Hebebrand J, Wabitsch M.

Pediatr Obes. 2020 Jan;15(1):e12577. doi: 10.1111/ijpo.12577. Epub 2019 Oct 31.

PMID:
31670905
13.

Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology.

Sonner JK, Keil M, Falk-Paulsen M, Mishra N, Rehman A, Kramer M, Deumelandt K, Röwe J, Sanghvi K, Wolf L, von Landenberg A, Wolff H, Bharti R, Oezen I, Lanz TV, Wanke F, Tang Y, Brandao I, Mohapatra SR, Epping L, Grill A, Röth R, Niesler B, Meuth SG, Opitz CA, Okun JG, Reinhardt C, Kurschus FC, Wick W, Bode HB, Rosenstiel P, Platten M.

Nat Commun. 2019 Oct 25;10(1):4877. doi: 10.1038/s41467-019-12776-4.

14.

CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria.

Wang G, Zhao Z, Ke J, Engel Y, Shi YM, Robinson D, Bingol K, Zhang Z, Bowen B, Louie K, Wang B, Evans R, Miyamoto Y, Cheng K, Kosina S, De Raad M, Silva L, Luhrs A, Lubbe A, Hoyt DW, Francavilla C, Otani H, Deutsch S, Washton NM, Rubin EM, Mouncey NJ, Visel A, Northen T, Cheng JF, Bode HB, Yoshikuni Y.

Nat Microbiol. 2019 Dec;4(12):2498-2510. doi: 10.1038/s41564-019-0573-8. Epub 2019 Oct 14.

PMID:
31611640
15.

New-Onset Diffuse Parenchymal Lung Disease in a 52-Year-Old Woman With Ulcerative Colitis.

De Backer E, Bode H, Baert F.

Gastroenterology. 2020 Feb;158(3):478-479. doi: 10.1053/j.gastro.2019.09.016. Epub 2019 Sep 24. No abstract available.

PMID:
31560891
16.

An atypical case of a pulmonary mass in an immunocompromised patient.

Cardinaels N, Van Rompaey W, Bos S, Bode H, Tousseyn T, Van Bleyenbergh P.

Acta Clin Belg. 2019 Aug 17:1-5. doi: 10.1080/17843286.2019.1655232. [Epub ahead of print]

PMID:
31423951
17.

(±)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus Alternaria alternata P1210 Isolated from the Halophyte Salicornia sp.

Shi YN, Pusch S, Shi YM, Richter C, Maciá-Vicente JG, Schwalbe H, Kaiser M, Opatz T, Bode HB.

J Org Chem. 2019 Sep 6;84(17):11203-11209. doi: 10.1021/acs.joc.9b01229. Epub 2019 Aug 27.

PMID:
31409073
18.

Production of a photohexapeptide library from entomopathogenic Photorhabdus asymbiotica PB68.1.

Zhao L, Bode HB.

Org Biomol Chem. 2019 Aug 28;17(34):7858-7862. doi: 10.1039/c9ob01489f.

PMID:
31403156
19.

Molecular mechanism of polyketide shortening in anthraquinone biosynthesis of Photorhabdus luminescens.

Zhou Q, Bräuer A, Adihou H, Schmalhofer M, Saura P, Grammbitter GLC, Kaila VRI, Groll M, Bode HB.

Chem Sci. 2019 May 14;10(25):6341-6349. doi: 10.1039/c9sc00749k. eCollection 2019 Jul 7.

20.

The lichen symbiosis re-viewed through the genomes of Cladonia grayi and its algal partner Asterochloris glomerata.

Armaleo D, Müller O, Lutzoni F, Andrésson ÓS, Blanc G, Bode HB, Collart FR, Dal Grande F, Dietrich F, Grigoriev IV, Joneson S, Kuo A, Larsen PE, Logsdon JM Jr, Lopez D, Martin F, May SP, McDonald TR, Merchant SS, Miao V, Morin E, Oono R, Pellegrini M, Rubinstein N, Sanchez-Puerta MV, Savelkoul E, Schmitt I, Slot JC, Soanes D, Szövényi P, Talbot NJ, Veneault-Fourrey C, Xavier BB.

BMC Genomics. 2019 Jul 23;20(1):605. doi: 10.1186/s12864-019-5629-x.

21.

Microbe-driven chemical ecology: past, present and future.

Schmidt R, Ulanova D, Wick LY, Bode HB, Garbeva P.

ISME J. 2019 Nov;13(11):2656-2663. doi: 10.1038/s41396-019-0469-x. Epub 2019 Jul 9. Review.

PMID:
31289346
22.

Outcome of lung transplantation in non-idiopathic pulmonary fibrosis interstitial lung disease.

Bode H, Verleden SE, Wuyts WA, Yserbyt J, Verleden GM, Vos R.

Clin Transplant. 2019 Oct;33(10):e13661. doi: 10.1111/ctr.13661. Epub 2019 Aug 6.

PMID:
31286560
23.

Modification and de novo design of non-ribosomal peptide synthetases using specific assembly points within condensation domains.

Bozhüyük KAJ, Linck A, Tietze A, Kranz J, Wesche F, Nowak S, Fleischhacker F, Shi YN, Grün P, Bode HB.

Nat Chem. 2019 Jul;11(7):653-661. doi: 10.1038/s41557-019-0276-z. Epub 2019 Jun 10.

PMID:
31182822
24.

Cyclo(tetrahydroxybutyrate) production is sufficient to distinguish between Xenorhabdus and Photorhabdus isolates in Thailand.

Tobias NJ, Parra-Rojas C, Shi YN, Shi YM, Simonyi S, Thanwisai A, Vitta A, Chantratita N, Hernandez-Vargas EA, Bode HB.

Environ Microbiol. 2019 Aug;21(8):2921-2932. doi: 10.1111/1462-2920.14685. Epub 2019 Jun 10.

PMID:
31102315
25.

Heterogeneity in Bacterial Specialized Metabolism.

Tobias NJ, Bode HB.

J Mol Biol. 2019 Nov 22;431(23):4589-4598. doi: 10.1016/j.jmb.2019.04.042. Epub 2019 May 6. Review.

PMID:
31071325
26.

Expanding the Isoprenoid Building Block Repertoire with an IPP Methyltransferase from Streptomyces monomycini.

Drummond L, Kschowak MJ, Breitenbach J, Wolff H, Shi YM, Schrader J, Bode HB, Sandmann G, Buchhaupt M.

ACS Synth Biol. 2019 Jun 21;8(6):1303-1313. doi: 10.1021/acssynbio.8b00525. Epub 2019 May 14.

PMID:
31059642
27.

An Uncommon Type II PKS Catalyzes Biosynthesis of Aryl Polyene Pigments.

Grammbitter GLC, Schmalhofer M, Karimi K, Shi YM, Schöner TA, Tobias NJ, Morgner N, Groll M, Bode HB.

J Am Chem Soc. 2019 Oct 23;141(42):16615-16623. doi: 10.1021/jacs.8b10776. Epub 2019 Apr 3.

PMID:
30908039
28.

Dual phenazine gene clusters enable diversification during biosynthesis.

Shi YM, Brachmann AO, Westphalen MA, Neubacher N, Tobias NJ, Bode HB.

Nat Chem Biol. 2019 Apr;15(4):331-339. doi: 10.1038/s41589-019-0246-1. Epub 2019 Mar 18.

PMID:
30886436
29.

Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila.

Wesche F, Adihou H, Wichelhaus TA, Bode HB.

Beilstein J Org Chem. 2019 Feb 25;15:535-541. doi: 10.3762/bjoc.15.47. eCollection 2019.

30.

Reprogramming Promiscuous Nonribosomal Peptide Synthetases for Production of Specific Peptides.

Cai X, Zhao L, Bode HB.

Org Lett. 2019 Apr 5;21(7):2116-2120. doi: 10.1021/acs.orglett.9b00395. Epub 2019 Mar 12.

PMID:
30859835
31.

Natural C. elegans Microbiota Protects against Infection via Production of a Cyclic Lipopeptide of the Viscosin Group.

Kissoyan KAB, Drechsler M, Stange EL, Zimmermann J, Kaleta C, Bode HB, Dierking K.

Curr Biol. 2019 Mar 18;29(6):1030-1037.e5. doi: 10.1016/j.cub.2019.01.050. Epub 2019 Feb 28.

32.

Anti-tubercular activity of a natural stilbene and its synthetic derivatives.

Reinheimer C, Büttner D, Proschak E, Bode HB, Kempf VAJ, Wichelhaus TA.

GMS Infect Dis. 2018 Feb 1;6:Doc01. doi: 10.3205/id000036. eCollection 2018.

33.

Biosynthetic Gene Content of the 'Perfume Lichens' Evernia prunastri and Pseudevernia furfuracea.

Calchera A, Dal Grande F, Bode HB, Schmitt I.

Molecules. 2019 Jan 8;24(1). pii: E203. doi: 10.3390/molecules24010203.

34.

Fabclavine biosynthesis in X. szentirmaii: shortened derivatives and characterization of the thioester reductase FclG and the condensation domain-like protein FclL.

Wenski SL, Kolbert D, Grammbitter GLC, Bode HB.

J Ind Microbiol Biotechnol. 2019 Mar;46(3-4):565-572. doi: 10.1007/s10295-018-02124-8. Epub 2019 Jan 4.

PMID:
30610410
35.

An uncommon histopathological diagnosis.

Bode H, Sciot R, Werbrouck E, Geusens E, Deroose CM, Nackaerts K.

Breathe (Sheff). 2018 Dec;14(4):311-316. doi: 10.1183/20734735.027418.

36.

Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS.

Hacker C, Cai X, Kegler C, Zhao L, Weickhmann AK, Wurm JP, Bode HB, Wöhnert J.

Nat Commun. 2018 Oct 19;9(1):4366. doi: 10.1038/s41467-018-06712-1.

37.

Methionine-Containing Rhabdopeptide/Xenortide-like Peptides from Heterologous Expression of the Biosynthetic Gene Cluster kj12ABC in Escherichia coli.

Zhao L, Cai X, Kaiser M, Bode HB.

J Nat Prod. 2018 Oct 26;81(10):2292-2295. doi: 10.1021/acs.jnatprod.8b00425. Epub 2018 Oct 10.

PMID:
30302998
38.

[Risk Factors for Mental Health Problems in Children with Cerebral Palsy and Spina Bifida].

Kohleis K, Storck M, Geissler-Preuss S, Hirsch A, Kuhn FD, Ortfeld S, Rapp M, Bode H.

Klin Padiatr. 2019 Jan;231(1):28-34. doi: 10.1055/a-0664-0832. Epub 2018 Sep 4. German.

PMID:
30180264
39.

Correction: Velvet domain protein VosA represses the zinc cluster transcription factor SclB regulatory network for Aspergillus nidulans asexual development, oxidative stress response and secondary metabolism.

Thieme KG, Gerke J, Sasse C, Valerius O, Thieme S, Karimi R, Heinrich AK, Finkernagel F, Smith K, Bode HB, Freitag M, Ram AFJ, Braus GH.

PLoS Genet. 2018 Aug 29;14(8):e1007638. doi: 10.1371/journal.pgen.1007638. eCollection 2018 Aug.

40.

Predictive Value of Thompson-Score for Long-Term Neurological and Cognitive Outcome in Term Newborns with Perinatal Asphyxia and Hypoxic-Ischemic Encephalopathy Undergoing Controlled Hypothermia Treatment.

Mendler MR, Mendler I, Hassan MA, Mayer B, Bode H, Hummler HD.

Neonatology. 2018;114(4):341-347. doi: 10.1159/000490721. Epub 2018 Aug 21.

PMID:
30130752
41.

Rhabdopeptide/Xenortide-like Peptides from Xenorhabdus innexi with Terminal Amines Showing Potent Antiprotozoal Activity.

Zhao L, Kaiser M, Bode HB.

Org Lett. 2018 Sep 7;20(17):5116-5120. doi: 10.1021/acs.orglett.8b01975. Epub 2018 Aug 10.

PMID:
30095261
42.

Velvet domain protein VosA represses the zinc cluster transcription factor SclB regulatory network for Aspergillus nidulans asexual development, oxidative stress response and secondary metabolism.

Thieme KG, Gerke J, Sasse C, Valerius O, Thieme S, Karimi R, Heinrich AK, Finkernagel F, Smith K, Bode HB, Freitag M, Ram AFJ, Braus GH.

PLoS Genet. 2018 Jul 25;14(7):e1007511. doi: 10.1371/journal.pgen.1007511. eCollection 2018 Jul. Erratum in: PLoS Genet. 2018 Aug 29;14(8):e1007638.

43.

Refining the Natural Product Repertoire in Entomopathogenic Bacteria.

Tobias NJ, Shi YM, Bode HB.

Trends Microbiol. 2018 Oct;26(10):833-840. doi: 10.1016/j.tim.2018.04.007. Epub 2018 May 22. Review.

PMID:
29801772
44.

Combined Approach of Backbone Amide Linking and On-Resin N-Methylation for the Synthesis of Bioactive and Metabolically Stable Peptides.

Wesche F, Adihou H, Kaiser A, Wurglics M, Schubert-Zsilavecz M, Kaiser M, Bode HB.

J Med Chem. 2018 May 10;61(9):3930-3938. doi: 10.1021/acs.jmedchem.7b01809. Epub 2018 Apr 20.

PMID:
29660276
45.

The benzodiazepine-like natural product tilivalline is produced by the entomopathogenic bacterium Xenorhabdus eapokensis.

Wolff H, Bode HB.

PLoS One. 2018 Mar 29;13(3):e0194297. doi: 10.1371/journal.pone.0194297. eCollection 2018.

46.

Natural Product Diversification Mediated by Alternative Transcriptional Starting.

Tobias NJ, Linck A, Bode HB.

Angew Chem Int Ed Engl. 2018 May 14;57(20):5699-5702. doi: 10.1002/anie.201713199. Epub 2018 Apr 14.

PMID:
29508935
47.

Effects of Levetiracetam and Sulthiame on EEG in benign epilepsy with centrotemporal spikes: A randomized controlled trial.

Tacke M, Borggraefe I, Gerstl L, Heinen F, Vill K, Bonfert M, Bast T; HEAD Study group, Neubauer BA, Baumeister F, Baethmann M, Bentele K, Blank C, Blank HM, Bode H, Bosch F, Brandl U, Brockmann K, Dahlem P, Ernst JP, Feldmann E, Fiedler A, Gerigk M, Heß S, Hikel C, Hoffmann HG, Kieslich M, Klepper J, Kluger G, Koch H, Koch W, Korinthenberg R, Krois I, Kühne H, Kurlemann G, Mandl M, Mause U, Navratil P, Opp J, Penzien J, Prietsch V, Quattländer A, Rating D, Schara U, Shamdeen MG, Sprinz A, Wendker-Magrabi H, Stephani U, Muhle H, Straßburg HM, Töpke B, Trollmann R, Tuschen-Hofstätter E, Waltz S, Weber G, Wien FU, Wolff M, Polster T, Freitag H, Sönmez Ö, Reinhardt K, Traus M, Hoovey Z.

Seizure. 2018 Mar;56:115-120. doi: 10.1016/j.seizure.2018.01.015. Epub 2018 Feb 3.

48.

Georatusin, a Specific Antiparasitic Polyketide-Peptide Hybrid from the Fungus Geomyces auratus.

Shi YM, Richter C, Challinor VL, Grün P, Girela Del Rio A, Kaiser M, Schüffler A, Piepenbring M, Schwalbe H, Bode HB.

Org Lett. 2018 Mar 16;20(6):1563-1567. doi: 10.1021/acs.orglett.8b00293. Epub 2018 Feb 23.

PMID:
29474084
49.

De novo design and engineering of non-ribosomal peptide synthetases.

Bozhüyük KAJ, Fleischhacker F, Linck A, Wesche F, Tietze A, Niesert CP, Bode HB.

Nat Chem. 2018 Mar;10(3):275-281. doi: 10.1038/nchem.2890. Epub 2017 Dec 11.

PMID:
29461518
50.

Metabolomics-based chemotaxonomy of root endophytic fungi for natural products discovery.

Maciá-Vicente JG, Shi YN, Cheikh-Ali Z, Grün P, Glynou K, Kia SH, Piepenbring M, Bode HB.

Environ Microbiol. 2018 Mar;20(3):1253-1270. doi: 10.1111/1462-2920.14072. Epub 2018 Mar 14.

PMID:
29441701

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