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Items: 11

1.

Absorption, metabolism, and excretion of oral ¹⁴C radiolabeled ibrutinib: an open-label, phase I, single-dose study in healthy men.

Scheers E, Leclercq L, de Jong J, Bode N, Bockx M, Laenen A, Cuyckens F, Skee D, Murphy J, Sukbuntherng J, Mannens G.

Drug Metab Dispos. 2015 Feb;43(2):289-97. doi: 10.1124/dmd.114.060061. Epub 2014 Dec 8.

2.

High volume injections of biological samples for sensitive metabolite profiling and quantitation.

Koppen V, Jones R, Bockx M, Cuyckens F.

J Chromatogr A. 2014 Nov 1;1372C:102-109. doi: 10.1016/j.chroma.2014.10.087. [Epub ahead of print]

PMID:
25465008
3.

Identifying metabolite ions of peptide drugs in the presence of an in vivo matrix background.

Cuyckens F, Dillen L, Cools W, Bockx M, Vereyken L, de Vries R, Mortishire-Smith RJ.

Bioanalysis. 2012 Mar;4(5):595-604. doi: 10.4155/bio.11.333.

PMID:
22409556
4.

Speciation analysis of bromine-containing drug metabolites in feces samples from a human in vivo study by means of HPLC/ICP-MS combined with on-line isotope dilution.

Meermann B, Bockx M, Laenen A, Van Looveren C, Cuyckens F, Vanhaecke F.

Anal Bioanal Chem. 2012 Jan;402(1):439-48. doi: 10.1007/s00216-011-5339-y. Epub 2011 Aug 30.

PMID:
21877185
5.

In vitro studies on the metabolism of trabectedin (YONDELIS) in monkey and man, including human CYP reaction phenotyping.

Vermeir M, Hemeryck A, Cuyckens F, Francesch A, Bockx M, Van Houdt J, Steemans K, Mannens G, Avilés P, De Coster R.

Biochem Pharmacol. 2009 May 15;77(10):1642-54. doi: 10.1016/j.bcp.2009.02.020. Epub 2009 Mar 10.

PMID:
19426702
6.

Metabolism and excretion of RWJ-333369 [1,2-ethanediol, 1-(2-chlorophenyl)-, 2-carbamate, (S)-] in mice, rats, rabbits, and dogs.

Mamidi RN, Mannens G, Annaert P, Hendrickx J, Goris I, Bockx M, Janssen CG, Kao M, Kelley MF, Meuldermans W.

Drug Metab Dispos. 2007 Apr;35(4):566-75. Epub 2007 Jan 12.

7.

The absorption, metabolism, and excretion of the novel neuromodulator RWJ-333369 (1,2-ethanediol, [1-2-chlorophenyl]-, 2-carbamate, [S]-) in humans.

Mannens GS, Hendrickx J, Janssen CG, Chien S, Van Hoof B, Verhaeghe T, Kao M, Kelley MF, Goris I, Bockx M, Verreet B, Bialer M, Meuldermans W.

Drug Metab Dispos. 2007 Apr;35(4):554-65. Epub 2006 Aug 25.

8.
9.

Comparative metabolism of flunarizine in rats, dogs and man: an in vitro study with subcellular liver fractions and isolated hepatocytes.

Lavrijsen K, van Houdt J, van Dyck D, Hendrickx J, Bockx M, Hurkmans R, Meuldermans W, Le Jeune L, Lauwers W, Heykants J.

Xenobiotica. 1992 Jul;22(7):815-36.

PMID:
1455902
10.

Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.

Lavrijsen K, Van Houdt J, Van Dyck D, Hendrickx J, Lauwers W, Hurkmans R, Bockx M, Janssen C, Meuldermans W, Heykants J.

Drug Metab Dispos. 1990 Sep-Oct;18(5):704-10.

PMID:
1981724
11.

Excretion and biotransformation of cisapride in dogs and humans after oral administration.

Meuldermans W, Van Peer A, Hendrickx J, Lauwers W, Swysen E, Bockx M, Woestenborghs R, Heykants J.

Drug Metab Dispos. 1988 May-Jun;16(3):403-9.

PMID:
2900732

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