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Items: 41

1.

Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.

Luther J, Yorgan TA, Rolvien T, Ulsamer L, Koehne T, Liao N, Keller D, Vollersen N, Teufel S, Neven M, Peters S, Schweizer M, Trumpp A, Rosigkeit S, Bockamp E, Mundlos S, Kornak U, Oheim R, Amling M, Schinke T, David JP.

Sci Transl Med. 2018 Nov 7;10(466). pii: eaau7137. doi: 10.1126/scitranslmed.aau7137.

PMID:
30404864
2.

Monitoring Translation Activity of mRNA-Loaded Nanoparticles in Mice.

Rosigkeit S, Meng M, Grunwitz C, Gomes P, Kreft A, Hayduk N, Heck R, Pickert G, Ziegler K, Abassi Y, Röder J, Kaps L, Vascotto F, Beissert T, Witzel S, Kuhn A, Diken M, Schuppan D, Sahin U, Haas H, Bockamp E.

Mol Pharm. 2018 Sep 4;15(9):3909-3919. doi: 10.1021/acs.molpharmaceut.8b00370. Epub 2018 Aug 9.

PMID:
30028629
3.

Enhanced protection of C57 BL/6 vs Balb/c mice to melanoma liver metastasis is mediated by NK cells.

Foerster F, Boegel S, Heck R, Pickert G, Rüssel N, Rosigkeit S, Bros M, Strobl S, Kaps L, Aslam M, Diken M, Castle J, Sahin U, Tuettenberg A, Bockamp E, Schuppan D.

Oncoimmunology. 2017 Dec 26;7(4):e1409929. doi: 10.1080/2162402X.2017.1409929. eCollection 2018.

4.

The immune contexture of hepatocellular carcinoma predicts clinical outcome.

Foerster F, Hess M, Gerhold-Ay A, Marquardt JU, Becker D, Galle PR, Schuppan D, Binder H, Bockamp E.

Sci Rep. 2018 Mar 29;8(1):5351. doi: 10.1038/s41598-018-21937-2.

5.

IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal.

Weng SY, Wang X, Vijayan S, Tang Y, Kim YO, Padberg K, Regen T, Molokanova O, Chen T, Bopp T, Schild H, Brombacher F, Crosby JR, McCaleb ML, Waisman A, Bockamp E, Schuppan D.

EBioMedicine. 2018 Mar;29:92-103. doi: 10.1016/j.ebiom.2018.01.028. Epub 2018 Feb 17.

6.

Characterization of a Fetal Liver Cell Population Endowed with Long-Term Multiorgan Endothelial Reconstitution Potential.

Cañete A, Comaills V, Prados I, Castro AM, Hammad S, Ybot-Gonzalez P, Bockamp E, Hengstler JG, Gottgens B, Sánchez MJ.

Stem Cells. 2017 Feb;35(2):507-521. doi: 10.1002/stem.2494. Epub 2016 Sep 28.

7.

Genetic enhancement of microsomal epoxide hydrolase improves metabolic detoxification but impairs cerebral blood flow regulation.

Marowsky A, Haenel K, Bockamp E, Heck R, Rutishauser S, Mule N, Kindler D, Rudin M, Arand M.

Arch Toxicol. 2016 Dec;90(12):3017-3027. Epub 2016 Feb 2.

8.

Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model.

Cabezas-Wallscheid N, Eichwald V, de Graaf J, Löwer M, Lehr HA, Kreft A, Eshkind L, Hildebrandt A, Abassi Y, Heck R, Dehof AK, Ohngemach S, Sprengel R, Wörtge S, Schmitt S, Lotz J, Meyer C, Kindler T, Zhang DE, Kaina B, Castle JC, Trumpp A, Sahin U, Bockamp E.

EMBO Mol Med. 2013 Dec;5(12):1804-20. doi: 10.1002/emmm.201302661. Epub 2013 Oct 4.

9.

STAT5 is crucial to maintain leukemic stem cells in acute myelogenous leukemias induced by MOZ-TIF2.

Tam WF, Hähnel PS, Schüler A, Lee BH, Okabe R, Zhu N, Pante SV, Raffel G, Mercher T, Wernig G, Bockamp E, Sasca D, Kreft A, Robinson GW, Hennighausen L, Gilliland DG, Kindler T.

Cancer Res. 2013 Jan 1;73(1):373-84. doi: 10.1158/0008-5472.CAN-12-0255. Epub 2012 Nov 13.

10.

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression.

Reis M, Czupalla CJ, Ziegler N, Devraj K, Zinke J, Seidel S, Heck R, Thom S, Macas J, Bockamp E, Fruttiger M, Taketo MM, Dimmeler S, Plate KH, Liebner S.

J Exp Med. 2012 Aug 27;209(9):1611-27. doi: 10.1084/jem.20111580. Epub 2012 Aug 20.

11.

Desmoglein 2 mutant mice develop cardiac fibrosis and dilation.

Krusche CA, Holthöfer B, Hofe V, van de Sandt AM, Eshkind L, Bockamp E, Merx MW, Kant S, Windoffer R, Leube RE.

Basic Res Cardiol. 2011 Jun;106(4):617-33. doi: 10.1007/s00395-011-0175-y. Epub 2011 Apr 1.

12.

Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expression.

Wörtge S, Eshkind L, Cabezas-Wallscheid N, Lakaye B, Kim J, Heck R, Abassi Y, Diken M, Sprengel R, Bockamp E.

BMC Dev Biol. 2010 Sep 3;10:95. doi: 10.1186/1471-213X-10-95.

13.

Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration.

Hoehme S, Brulport M, Bauer A, Bedawy E, Schormann W, Hermes M, Puppe V, Gebhardt R, Zellmer S, Schwarz M, Bockamp E, Timmel T, Hengstler JG, Drasdo D.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10371-6. doi: 10.1073/pnas.0909374107. Epub 2010 May 19.

14.

Stem cells in chemical carcinogenesis.

Dietrich C, Weiss C, Bockamp E, Brisken C, Roskams T, Morris R, Oesch-Bartlomowicz B, Oesch F.

Arch Toxicol. 2010 Mar;84(3):245-51. doi: 10.1007/s00204-009-0491-2. Epub 2009 Nov 26. No abstract available.

PMID:
19941131
15.

In vivo fate mapping with SCL regulatory elements identifies progenitors for primitive and definitive hematopoiesis in mice.

Bockamp E, Antunes C, Liebner S, Schmitt S, Cabezas-Wallscheid N, Heck R, Ohnngemach S, Oesch-Bartlomowicz B, Rickert C, Sanchez MJ, Hengstler J, Kaina B, Wilson A, Trumpp A, Eshkind L.

Mech Dev. 2009 Oct;126(10):863-72. doi: 10.1016/j.mod.2009.07.005. Epub 2009 Jul 23.

16.

Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair.

Wilson A, Laurenti E, Oser G, van der Wath RC, Blanco-Bose W, Jaworski M, Offner S, Dunant CF, Eshkind L, Bockamp E, Lió P, Macdonald HR, Trumpp A.

Cell. 2008 Dec 12;135(6):1118-29. doi: 10.1016/j.cell.2008.10.048. Erratum in: Cell. 2009 Jul 10;138(1):209.

17.

Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regeneration.

Bockamp E, Sprengel R, Eshkind L, Lehmann T, Braun JM, Emmrich F, Hengstler JG.

Regen Med. 2008 Mar;3(2):217-35. doi: 10.2217/17460751.3.2.217.

PMID:
18307405
18.

Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues.

Hameyer D, Loonstra A, Eshkind L, Schmitt S, Antunes C, Groen A, Bindels E, Jonkers J, Krimpenfort P, Meuwissen R, Rijswijk L, Bex A, Berns A, Bockamp E.

Physiol Genomics. 2007 Sep 19;31(1):32-41. Epub 2007 Apr 24.

PMID:
17456738
19.

Generation and characterization of tTS-H4: a novel transcriptional repressor that is compatible with the reverse tetracycline-controlled TET-ON system.

Bockamp E, Christel C, Hameyer D, Khobta A, Maringer M, Reis M, Heck R, Cabezas-Wallscheid N, Epe B, Oesch-Bartlomowicz B, Kaina B, Schmitt S, Eshkind L.

J Gene Med. 2007 Apr;9(4):308-18.

PMID:
17330923
20.

Oncogene-blocking therapies: new insights from conditional mouse tumor models.

Hengstler JG, Bockamp EO, Hermes M, Brulport M, Bauer A, Schormann W, Schiffer IB, Hausherr C, Eshkind L, Antunes C, Franzen A, Krishnamurthi K, Lausch E, Lessig R, Chakrabarti T, Prawitt D, Zabel B, Spangenberg C.

Curr Cancer Drug Targets. 2006 Nov;6(7):603-12. Review.

PMID:
17100566
21.

Generation of human hepatocytes by stem cell technology: definition of the hepatocyte.

Hengstler JG, Brulport M, Schormann W, Bauer A, Hermes M, Nussler AK, Fandrich F, Ruhnke M, Ungefroren H, Griffin L, Bockamp E, Oesch F, von Mach MA.

Expert Opin Drug Metab Toxicol. 2005 Jun;1(1):61-74. Review.

PMID:
16922653
22.

Tetracycline-controlled transgenic targeting from the SCL locus directs conditional expression to erythrocytes, megakaryocytes, granulocytes, and c-kit-expressing lineage-negative hematopoietic cells.

Bockamp E, Antunes C, Maringer M, Heck R, Presser K, Beilke S, Ohngemach S, Alt R, Cross M, Sprengel R, Hartwig U, Kaina B, Schmitt S, Eshkind L.

Blood. 2006 Sep 1;108(5):1533-41. Epub 2006 May 4.

23.

Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways.

Oesch-Bartlomowicz B, Huelster A, Wiss O, Antoniou-Lipfert P, Dietrich C, Arand M, Weiss C, Bockamp E, Oesch F.

Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9218-23. Epub 2005 Jun 21.

24.

Premature senescence is a primary fail-safe mechanism of ERBB2-driven tumorigenesis in breast carcinoma cells.

Trost TM, Lausch EU, Fees SA, Schmitt S, Enklaar T, Reutzel D, Brixel LR, Schmidtke P, Maringer M, Schiffer IB, Heimerdinger CK, Hengstler JG, Fritz G, Bockamp EO, Prawitt D, Zabel BU, Spangenberg C.

Cancer Res. 2005 Feb 1;65(3):840-9.

25.

4-Epidoxycycline: an alternative to doxycycline to control gene expression in conditional mouse models.

Eger K, Hermes M, Uhlemann K, Rodewald S, Ortwein J, Brulport M, Bauer AW, Schormann W, Lupatsch F, Schiffer IB, Heimerdinger CK, Gebhard S, Spangenberg C, Prawitt D, Trost T, Zabel B, Sauer C, Tanner B, Kolbl H, Krugel U, Franke H, Illes P, Madaj-Sterba P, Bockamp EO, Beckers T, Hengstler JG.

Biochem Biophys Res Commun. 2004 Oct 22;323(3):979-86.

PMID:
15381096
26.

RNAi knock-down mice: an emerging technology for post-genomic functional genetics.

Prawitt D, Brixel L, Spangenberg C, Eshkind L, Heck R, Oesch F, Zabel B, Bockamp E.

Cytogenet Genome Res. 2004;105(2-4):412-21. Review.

PMID:
15237229
27.

Of mice and models: improved animal models for biomedical research.

Bockamp E, Maringer M, Spangenberg C, Fees S, Fraser S, Eshkind L, Oesch F, Zabel B.

Physiol Genomics. 2002 Dec 3;11(3):115-32. Epub 2002 Dec 3. Review.

PMID:
12464688
28.

Selective rescue of early haematopoietic progenitors in Scl(-/-) mice by expressing Scl under the control of a stem cell enhancer.

Sánchez MJ, Bockamp EO, Miller J, Gambardella L, Green AR.

Development. 2001 Dec;128(23):4815-27.

29.

Distinct 5' SCL enhancers direct transcription to developing brain, spinal cord, and endothelium: neural expression is mediated by GATA factor binding sites.

Sinclair AM, Göttgens B, Barton LM, Stanley ML, Pardanaud L, Klaine M, Gering M, Bahn S, Sanchez M, Bench AJ, Fordham JL, Bockamp E, Green AR.

Dev Biol. 1999 May 1;209(1):128-42.

30.

Transcriptional regulation of the stem cell leukemia gene by PU.1 and Elf-1.

Bockamp EO, Fordham JL, Göttgens B, Murrell AM, Sanchez MJ, Green AR.

J Biol Chem. 1998 Oct 30;273(44):29032-42.

31.
32.

Distinct mechanisms direct SCL/tal-1 expression in erythroid cells and CD34 positive primitive myeloid cells.

Bockamp EO, McLaughlin F, Göttgens B, Murrell AM, Elefanty AG, Green AR.

J Biol Chem. 1997 Mar 28;272(13):8781-90.

33.

Lineage-restricted regulation of the murine SCL/TAL-1 promoter.

Bockamp EO, McLaughlin F, Murrell AM, Göttgens B, Robb L, Begley CG, Green AR.

Blood. 1995 Aug 15;86(4):1502-14.

34.

Discordant regulation of SCL/TAL-1 mRNA and protein during erythroid differentiation.

Murrell AM, Bockamp EO, Göttgens B, Chan YS, Cross MA, Heyworth CM, Green AR.

Oncogene. 1995 Jul 6;11(1):131-9.

PMID:
7624120
35.

Expression of lineage restricted transcription factors precedes lineage specific differentiation in a multipotent haemopoietic progenitor cell line.

Cross MA, Heyworth CM, Murrell AM, Bockamp EO, Dexter TM, Green AR.

Oncogene. 1994 Oct;9(10):3013-6.

PMID:
8084606
36.

Transcription factors and the regulation of haemopoiesis: lessons from GATA and SCL proteins.

Bockamp EO, McLaughlin F, Murrell A, Green AR.

Bioessays. 1994 Jul;16(7):481-8. Review.

PMID:
7945276
37.

Structure of the gene encoding the murine SCL protein.

Begley CG, Robb L, Rockman S, Visvader J, Bockamp EO, Chan YS, Green AR.

Gene. 1994 Jan 28;138(1-2):93-9.

PMID:
8125323
38.

Isolation and molecular characterization of the swinepox virus thymidine kinase gene.

Feller JA, Massung RF, Turner PC, Gibbs EP, Bockamp EO, Beloso A, Talavera A, Viñuela E, Moyer RW.

Virology. 1991 Aug;183(2):578-85.

PMID:
1853562
39.
40.

Characterization and gene cloning of neurotactin, a Drosophila transmembrane protein related to cholinesterases.

de la Escalera S, Bockamp EO, Moya F, Piovant M, Jiménez F.

EMBO J. 1990 Nov;9(11):3593-601.

41.

Sequence and evolutionary relationships of African swine fever virus thymidine kinase.

Blasco R, López-Otín C, Muñóz M, Bockamp EO, Simón-Mateo C, Viñuela E.

Virology. 1990 Sep;178(1):301-4.

PMID:
2389555

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