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Items: 19


Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness.

Snyder JC, Rochelle LK, Ray C, Pack TF, Bock CB, Lubkov V, Lyerly HK, Waggoner AS, Barak LS, Caron MG.

J Biol Chem. 2017 Apr 28;292(17):7208-7222. doi: 10.1074/jbc.M116.756635. Epub 2017 Mar 8.


Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression.

Pirozzi CJ, Carpenter AB, Waitkus MS, Wang CY, Zhu H, Hansen LJ, Chen LH, Greer PK, Feng J, Wang Y, Bock CB, Fan P, Spasojevic I, McLendon RE, Bigner DD, He Y, Yan H.

Mol Cancer Res. 2017 May;15(5):507-520. doi: 10.1158/1541-7786.MCR-16-0485. Epub 2017 Feb 1.


Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice.

Irimia JM, Meyer CM, Peper CL, Zhai L, Bock CB, Previs SF, McGuinness OP, DePaoli-Roach A, Roach PJ.

J Biol Chem. 2010 Apr 23;285(17):12851-61. doi: 10.1074/jbc.M110.106534. Epub 2010 Feb 23.


A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.

Savage DB, Zhai L, Ravikumar B, Choi CS, Snaar JE, McGuire AC, Wou SE, Medina-Gomez G, Kim S, Bock CB, Segvich DM, Solanky B, Deelchand D, Vidal-Puig A, Wareham NJ, Shulman GI, Karpe F, Taylor R, Pederson BA, Roach PJ, O'Rahilly S, DePaoli-Roach AA.

PLoS Med. 2008 Jan 29;5(1):e27. doi: 10.1371/journal.pmed.0050027. Erratum in: PLoS Med. 2008 Dec;5(12):e246.. Solanky, Bhavana [added]; Deelchand, Dinesh [added].


RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability.

Sharma S, Stumpo DJ, Balajee AS, Bock CB, Lansdorp PM, Brosh RM Jr, Blackshear PJ.

Mol Cell Biol. 2007 Mar;27(5):1784-94. Epub 2006 Dec 11.


RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

Aslanukov A, Bhowmick R, Guruju M, Oswald J, Raz D, Bush RA, Sieving PA, Lu X, Bock CB, Ferreira PA.

PLoS Genet. 2006 Oct;2(10):e177. Epub 2006 Sep 1.


Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation.

Jeoung NH, Wu P, Joshi MA, Jaskiewicz J, Bock CB, Depaoli-Roach AA, Harris RA.

Biochem J. 2006 Aug 1;397(3):417-25.


CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms.

Poe JC, Fujimoto Y, Hasegawa M, Haas KM, Miller AS, Sanford IG, Bock CB, Fujimoto M, Tedder TF.

Nat Immunol. 2004 Oct;5(10):1078-87. Epub 2004 Sep 19.


The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development.

Ramos SB, Stumpo DJ, Kennington EA, Phillips RS, Bock CB, Ribeiro-Neto F, Blackshear PJ.

Development. 2004 Oct;131(19):4883-93. Epub 2004 Sep 1.


Leukocyte migration is regulated by L-selectin endoproteolytic release.

Venturi GM, Tu L, Kadono T, Khan AI, Fujimoto Y, Oshel P, Bock CB, Miller AS, Albrecht RM, Kubes P, Steeber DA, Tedder TF.

Immunity. 2003 Nov;19(5):713-24.


Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses.

Haas KM, Hasegawa M, Steeber DA, Poe JC, Zabel MD, Bock CB, Karp DR, Briles DE, Weis JH, Tedder TF.

Immunity. 2002 Dec;17(6):713-23.


Insulin control of glycogen metabolism in knockout mice lacking the muscle-specific protein phosphatase PP1G/RGL.

Suzuki Y, Lanner C, Kim JH, Vilardo PG, Zhang H, Yang J, Cooper LD, Steele M, Kennedy A, Bock CB, Scrimgeour A, Lawrence JC Jr, DePaoli-Roach AA.

Mol Cell Biol. 2001 Apr;21(8):2683-94.


Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis.

Haribabu B, Verghese MW, Steeber DA, Sellars DD, Bock CB, Snyderman R.

J Exp Med. 2000 Aug 7;192(3):433-8.


Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.

Wang YM, Gainetdinov RR, Fumagalli F, Xu F, Jones SR, Bock CB, Miller GW, Wightman RM, Caron MG.

Neuron. 1997 Dec;19(6):1285-96.


Retinoic acid receptor alpha function in vertebrate limb skeletogenesis: a modulator of chondrogenesis.

Cash DE, Bock CB, Schughart K, Linney E, Underhill TM.

J Cell Biol. 1997 Jan 27;136(2):445-57.


CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.

Sato S, Miller AS, Inaoki M, Bock CB, Jansen PJ, Tang ML, Tedder TF.

Immunity. 1996 Dec;5(6):551-62.


MARCKS deficiency in mice leads to abnormal brain development and perinatal death.

Stumpo DJ, Bock CB, Tuttle JS, Blackshear PJ.

Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):944-8.


Transgenic mice expressing a constitutively active retinoic acid receptor in the lens exhibit ocular defects.

Balkan W, Klintworth GK, Bock CB, Linney E.

Dev Biol. 1992 Jun;151(2):622-5.


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