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Items: 22


The Saccharomyces cerevisiae Hrq1 and Pif1 DNA helicases synergistically modulate telomerase activity in vitro.

Nickens DG, Rogers CM, Bochman ML.

J Biol Chem. 2018 Sep 14;293(37):14481-14496. doi: 10.1074/jbc.RA118.004092. Epub 2018 Aug 1.


ComM is a hexameric helicase that promotes branch migration during natural transformation in diverse Gram-negative species.

Nero TM, Dalia TN, Wang JC, Kysela DT, Bochman ML, Dalia AB.

Nucleic Acids Res. 2018 Jul 6;46(12):6099-6111. doi: 10.1093/nar/gky343.


Promoter Boundaries for the luxCDABE and betIBA-proXWV Operons in Vibrio harveyi Defined by the Method Rapid Arbitrary PCR Insertion Libraries (RAIL).

Hustmyer CM, Simpson CA, Olney SG, Rusch DB, Bochman ML, van Kessel JC.

J Bacteriol. 2018 May 9;200(11). pii: e00724-17. doi: 10.1128/JB.00724-17. Print 2018 Jun 1.


The WYL Domain of the PIF1 Helicase from the Thermophilic Bacterium Thermotoga elfii is an Accessory Single-Stranded DNA Binding Module.

Andis NM, Sausen CW, Alladin A, Bochman ML.

Biochemistry. 2018 Feb 20;57(7):1108-1118. doi: 10.1021/acs.biochem.7b01233. Epub 2018 Jan 30.


Primary souring: A novel bacteria-free method for sour beer production.

Osburn K, Amaral J, Metcalf SR, Nickens DM, Rogers CM, Sausen C, Caputo R, Miller J, Li H, Tennessen JM, Bochman ML.

Food Microbiol. 2018 Apr;70:76-84. doi: 10.1016/ Epub 2017 Sep 14.


Saccharomyces cerevisiae Hrq1 helicase activity is affected by the sequence but not the length of single-stranded DNA.

Rogers CM, Bochman ML.

Biochem Biophys Res Commun. 2017 May 13;486(4):1116-1121. doi: 10.1016/j.bbrc.2017.04.003. Epub 2017 Apr 3.


Yeast Hrq1 shares structural and functional homology with the disease-linked human RecQ4 helicase.

Rogers CM, Wang JC, Noguchi H, Imasaki T, Takagi Y, Bochman ML.

Nucleic Acids Res. 2017 May 19;45(9):5217-5230. doi: 10.1093/nar/gkx151.


Terminal acidic shock inhibits sour beer bottle conditioning by Saccharomyces cerevisiae.

Rogers CM, Veatch D, Covey A, Staton C, Bochman ML.

Food Microbiol. 2016 Aug;57:151-8. doi: 10.1016/ Epub 2016 Mar 3.


DNA replication: Strand separation unravelled.

Bochman ML, Schwacha A.

Nature. 2015 Aug 13;524(7564):166-7. doi: 10.1038/nature14643. Epub 2015 Jul 29. No abstract available.


Roles of DNA helicases in the maintenance of genome integrity.

Bochman ML.

Mol Cell Oncol. 2014 Oct 29;1(3):e963429. doi: 10.4161/23723548.2014.963429. eCollection 2014 Jul-Sep. Review.


Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.

Zhou R, Zhang J, Bochman ML, Zakian VA, Ha T.

Elife. 2014 Apr 29;3:e02190. doi: 10.7554/eLife.02190.


Hrq1, a homolog of the human RecQ4 helicase, acts catalytically and structurally to promote genome integrity.

Bochman ML, Paeschke K, Chan A, Zakian VA.

Cell Rep. 2014 Jan 30;6(2):346-56. doi: 10.1016/j.celrep.2013.12.037. Epub 2014 Jan 16.


Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase.

Simon N, Bochman ML, Seguin S, Brodsky JL, Seibel WL, Schwacha A.

Biosci Rep. 2013 Oct 7;33(5). pii: e00072. doi: 10.1042/BSR20130083.


Pif1 family helicases suppress genome instability at G-quadruplex motifs.

Paeschke K, Bochman ML, Garcia PD, Cejka P, Friedman KL, Kowalczykowski SC, Zakian VA.

Nature. 2013 May 23;497(7450):458-62. doi: 10.1038/nature12149. Epub 2013 May 8.


DNA secondary structures: stability and function of G-quadruplex structures.

Bochman ML, Paeschke K, Zakian VA.

Nat Rev Genet. 2012 Nov;13(11):770-80. doi: 10.1038/nrg3296. Epub 2012 Oct 3. Review.


The Pif1 family in prokaryotes: what are our helicases doing in your bacteria?

Bochman ML, Judge CP, Zakian VA.

Mol Biol Cell. 2011 Jun 15;22(12):1955-9. doi: 10.1091/mbc.E11-01-0045.


The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.

Bochman ML, Schwacha A.

Nucleic Acids Res. 2010 Oct;38(18):6078-88. doi: 10.1093/nar/gkq422. Epub 2010 May 19.


Unwinding the functions of the Pif1 family helicases.

Bochman ML, Sabouri N, Zakian VA.

DNA Repair (Amst). 2010 Mar 2;9(3):237-49. doi: 10.1016/j.dnarep.2010.01.008. Epub 2010 Jan 25. Review.


The Mcm complex: unwinding the mechanism of a replicative helicase.

Bochman ML, Schwacha A.

Microbiol Mol Biol Rev. 2009 Dec;73(4):652-83. doi: 10.1128/MMBR.00019-09. Review.


Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability.

Bochman ML, Bell SP, Schwacha A.

Mol Cell Biol. 2008 Oct;28(19):5865-73. doi: 10.1128/MCB.00161-08. Epub 2008 Jul 28.


The Mcm2-7 complex has in vitro helicase activity.

Bochman ML, Schwacha A.

Mol Cell. 2008 Jul 25;31(2):287-93. doi: 10.1016/j.molcel.2008.05.020.


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