Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 27

1.

LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.

Bonday ZQ, Cortez GS, Grogan MJ, Antonysamy S, Weichert K, Bocchinfuso WP, Li F, Kennedy S, Li B, Mader MM, Arrowsmith CH, Brown PJ, Eram MS, Szewczyk MM, Barsyte-Lovejoy D, Vedadi M, Guccione E, Campbell RM.

ACS Med Chem Lett. 2018 Apr 23;9(7):612-617. doi: 10.1021/acsmedchemlett.8b00014. eCollection 2018 Jul 12.

2.

Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia.

Genin MJ, Bueno AB, Agejas Francisco J, Manninen PR, Bocchinfuso WP, Montrose-Rafizadeh C, Cannady EA, Jones TM, Stille JR, Raddad E, Reidy C, Cox A, Michael MD, Michael LF.

J Med Chem. 2015 Dec 24;58(24):9768-72. doi: 10.1021/acs.jmedchem.5b01161. Epub 2015 Dec 2.

PMID:
26568144
3.

HDX reveals unique fragment ligands for the vitamin D receptor.

Carson MW, Zhang J, Chalmers MJ, Bocchinfuso WP, Holifield KD, Masquelin T, Stites RE, Stayrook KR, Griffin PR, Dodge JA.

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3459-63. doi: 10.1016/j.bmcl.2014.05.070. Epub 2014 May 29.

PMID:
24974344
4.

Development of an HTS-compatible assay for discovery of RORα modulators using AlphaScreen® technology.

Istrate MA, Spicer TP, Wang Y, Bernard JA, Helvering LM, Bocchinfuso WP, Richardson TI, Zink R, Kumar N, Montrose-Rafizadeh C, Dodge J, Hodder P, Griffin PR.

J Biomol Screen. 2011 Feb;16(2):183-91. doi: 10.1177/1087057110389040.

5.

Expression of heregulin by mouse mammary tumor cells: role in activation of ErbB receptors.

Schmitt M, Walker MP, Richards RG, Bocchinfuso WP, Fukuda T, Medina D, Kittrell FS, Korach KS, DiAugustine RP.

Mol Carcinog. 2006 Jul;45(7):490-505.

PMID:
16482517
6.

Cyclic AMP-independent activation of CYP3A4 gene expression by forskolin.

Dowless MS, Barbee JL, Borchert KM, Bocchinfuso WP, Houck KA.

Eur J Pharmacol. 2005 Apr 4;512(1):9-13.

PMID:
15814084
7.

Tamoxifen versus aromatase inhibitors for breast cancer prevention.

Yue W, Wang JP, Li Y, Bocchinfuso WP, Korach KS, Devanesan PD, Rogan E, Cavalieri E, Santen RJ.

Clin Cancer Res. 2005 Jan 15;11(2 Pt 2):925s-30s. Review.

8.

The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand.

Burris TP, Montrose C, Houck KA, Osborne HE, Bocchinfuso WP, Yaden BC, Cheng CC, Zink RW, Barr RJ, Hepler CD, Krishnan V, Bullock HA, Burris LL, Galvin RJ, Bramlett K, Stayrook KR.

Mol Pharmacol. 2005 Mar;67(3):948-54. Epub 2004 Dec 15.

PMID:
15602004
9.

Genotoxic metabolites of estradiol in breast: potential mechanism of estradiol induced carcinogenesis.

Yue W, Santen RJ, Wang JP, Li Y, Verderame MF, Bocchinfuso WP, Korach KS, Devanesan P, Todorovic R, Rogan EG, Cavalieri EL.

J Steroid Biochem Mol Biol. 2003 Sep;86(3-5):477-86. Review.

PMID:
14623547
10.

Lack of ductal development in the absence of functional estrogen receptor alpha delays mammary tumor formation induced by transgenic expression of ErbB2/neu.

Hewitt SC, Bocchinfuso WP, Zhai J, Harrell C, Koonce L, Clark J, Myers P, Korach KS.

Cancer Res. 2002 May 15;62(10):2798-805.

11.
12.

Mammary gland development and tumorigenesis in estrogen receptor knockout mice.

Bocchinfuso WP, Korach KS.

J Mammary Gland Biol Neoplasia. 1997 Oct;2(4):323-34. Review.

PMID:
10935020
13.

Induction of mammary gland development in estrogen receptor-alpha knockout mice.

Bocchinfuso WP, Lindzey JK, Hewitt SC, Clark JA, Myers PH, Cooper R, Korach KS.

Endocrinology. 2000 Aug;141(8):2982-94.

PMID:
10919287
14.

A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha.

Bocchinfuso WP, Hively WP, Couse JF, Varmus HE, Korach KS.

Cancer Res. 1999 Apr 15;59(8):1869-76.

15.

Estrogen receptor residues required for stereospecific ligand recognition and activation.

Bocchinfuso WP, Korach KS.

Mol Endocrinol. 1997 May;11(5):587-94.

PMID:
9139802
16.

Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism.

Ramamoorthy K, Wang F, Chen IC, Norris JD, McDonnell DP, Leonard LS, Gaido KW, Bocchinfuso WP, Korach KS, Safe S.

Endocrinology. 1997 Apr;138(4):1520-7.

PMID:
9075711
17.

Potency of combined estrogenic pesticides.

Ramamoorthy K, Wang F, Chen IC, Safe S, Norris JD, McDonnell DP, Gaido KW, Bocchinfuso WP, Korach KS.

Science. 1997 Jan 17;275(5298):405-6. No abstract available.

18.

Mutational analysis of the estrogen receptor ligand-binding domain: influence of ligand structure and stereochemistry on transactivation.

Kohno H, Bocchinfuso WP, Gandini O, Curtis SW, Korach KS.

J Mol Endocrinol. 1996 Jun;16(3):277-85.

PMID:
8782086
19.

Sex hormone-binding globulin: gene organization and structure/function analyses.

Hammond GL, Bocchinfuso WP.

Horm Res. 1996;45(3-5):197-201. Review.

PMID:
8964583
20.

Sex hormone-binding globulin/androgen-binding protein: steroid-binding and dimerization domains.

Hammond GL, Bocchinfuso WP.

J Steroid Biochem Mol Biol. 1995 Jun;53(1-6):543-52. Review.

PMID:
7626508
21.

Resolution of the steroid-binding and dimerization domains of human sex hormone-binding globulin by expression in Escherichia coli.

Hildebrand C, Bocchinfuso WP, Dales D, Hammond GL.

Biochemistry. 1995 Mar 14;34(10):3231-8.

PMID:
7880817
22.

Serum distribution of two contraceptive progestins: 3-ketodesogestrel and gestodene.

Hammond GL, Bocchinfuso WP, Orava M, Smith CL, van den Ende A, van Enk A.

Contraception. 1994 Oct;50(4):301-18.

PMID:
7813219
24.

Selective removal of glycosylation sites from sex hormone-binding globulin by site-directed mutagenesis.

Bocchinfuso WP, Ma KL, Lee WM, Warmels-Rodenhiser S, Hammond GL.

Endocrinology. 1992 Nov;131(5):2331-6.

PMID:
1425432
25.

Molecular analyses of a human sex hormone-binding globulin variant: evidence for an additional carbohydrate chain.

Power SG, Bocchinfuso WP, Pallesen M, Warmels-Rodenhiser S, Van Baelen H, Hammond GL.

J Clin Endocrinol Metab. 1992 Oct;75(4):1066-70.

PMID:
1400872
26.

Structure/function analyses of human sex hormone-binding globulin by site-directed mutagenesis.

Bocchinfuso WP, Warmels-Rodenhiser S, Hammond GL.

FEBS Lett. 1992 Apr 20;301(2):227-30.

27.

Expression and differential glycosylation of human sex hormone-binding globulin by mammalian cell lines.

Bocchinfuso WP, Warmels-Rodenhiser S, Hammond GL.

Mol Endocrinol. 1991 Nov;5(11):1723-9.

PMID:
1723489

Supplemental Content

Loading ...
Support Center