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Ivabradine for treatment of heart failure.

Bocchi EA, Salemi VMC.

Expert Opin Drug Saf. 2019 May;18(5):393-402. doi: 10.1080/14740338.2019.1612873. Epub 2019 May 10. Review.


Letter by Vieira and Bocchi Regarding Article, "Association Between Ambient Air Pollution and Cardiac Morpho-Functional Phenotypes: Insights From the UK Biobank Population Imaging Study".

Vieira JL, Bocchi EA.

Circulation. 2019 Apr 9;139(15):1857-1858. doi: 10.1161/CIRCULATIONAHA.118.038033. No abstract available.


Prognosis and risk stratification in patients with decompensated heart failure receiving inotropic therapy.

Gomes C, Terhoch CB, Ayub-Ferreira SM, Conceição-Souza GE, Salemi VMC, Chizzola PR, Oliveira MT Jr, Lage SHG, Frioes F, Bocchi EA, Issa VS.

Open Heart. 2018 Dec 6;5(2):e000923. doi: 10.1136/openhrt-2018-000923. eCollection 2018.


The Globalization of Health Information in Different Languages: New Frontier With JACC Portuguese.

Bocchi EA.

J Am Coll Cardiol. 2019 Jan 29;73(3):375-377. doi: 10.1016/j.jacc.2018.11.021. No abstract available.


Aging, cardiotoxicity, and chemotherapy.

Bocchi EA, Avila MS, Ayub-Ferreira SM.

Aging (Albany NY). 2019 Jan 22;11(2):295-296. doi: 10.18632/aging.101776. No abstract available.


Hypotensive Effect of Heated Water-Based Exercise Persists After 12-Week Cessation of Training in Patients With Resistant Hypertension.

Guimãraes GV, Fernandes-Silva MM, Drager LF, de Barros Cruz LG, Castro RE, Ciolac EG, Bocchi EA.

Can J Cardiol. 2018 Dec;34(12):1641-1647. doi: 10.1016/j.cjca.2018.09.013. Epub 2018 Oct 5.


Archaea Symbiont of T. cruzi Infection May Explain Heart Failure in Chagas Disease.

Higuchi ML, Kawakami JT, Ikegami RN, Reis MM, Pereira JJ, Ianni BM, Buck P, Oliveira LMDS, Santos MHH, Hajjar LA, Bocchi EA.

Front Cell Infect Microbiol. 2018 Nov 21;8:412. doi: 10.3389/fcimb.2018.00412. eCollection 2018.


Comparative cost-effectiveness of surgery, angioplasty, or medical therapy in patients with multivessel coronary artery disease: MASS II trial.

Brandão SMG, Rezende PC, Rocca HB, Ju YT, de Lima ACP, Takiuti ME, Hueb W, Bocchi EA.

Cost Eff Resour Alloc. 2018 Nov 3;16:55. doi: 10.1186/s12962-018-0158-z. eCollection 2018. Review.


Diretriz Brasileira de Insuficiência Cardíaca Crônica e Aguda.

Comitê Coordenador da Diretriz de Insuficiência Cardíaca, Rohde LEP, Montera MW, Bocchi EA, Clausell NO, Albuquerque DC, Rassi S, Colafranceschi AS, Freitas AF Junior, Ferraz AS, Biolo A, Barretto ACP, Ribeiro ALP, Polanczyk CA, Gualandro DM, Almeida DR, Silva ERR, Figueiredo EL, Mesquita ET, Marcondes-Braga FG, Cruz FDD, Ramires FJA, Atik FA, Bacal F, Souza GEC, Almeida GLG Junior, Ribeiro GCA, Villacorta H Junior, Vieira JL, Souza JD Neto, Rossi JM Neto, Figueiredo JA Neto, Moura LAZ, Goldraich LA, Beck-da-Silva L, Danzmann LC, Canesin MF, Bittencourt MI, Garcia MI, Bonatto MG, Simões MV, Moreira MCV, Silva MMF, Olivera MT Junior, Silvestre OM, Schwartzmann PV, Bestetti RB, Rocha RM, Simões R, Pereira SB, Mangini S, Alves SMM, Ferreira SMA, Issa VS, Barzilai VS, Martins WA.

Arq Bras Cardiol. 2018 Sep;111(3):436-539. doi: 10.5935/abc.20180190. Portuguese. No abstract available. Erratum in: Arq Bras Cardiol. 2019 Jan;112(1):116.


Reply: Sacubitril/valsartan for Chagas' heart disease heart failure?

Bocchi EA, Rassi S, Veiga Guimarães G; Argentine, Chile, and Brazil SHIFT Investigators.

ESC Heart Fail. 2018 Dec;5(6):1072-1073. doi: 10.1002/ehf2.12344. Epub 2018 Oct 9. No abstract available.


Reply: Can Carvedilol Prevent Chemotherapy-Related Cardiotoxicity?: A Dream to Be Balanced With Tolerability.

Avila MS, Ayub Ferreira SM, Bocchi EA.

J Am Coll Cardiol. 2018 Sep 4;72(10):1182-1183. doi: 10.1016/j.jacc.2018.07.003. No abstract available.


Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure.

Scanavacca M, Bocchi EA.

Arq Bras Cardiol. 2018 Apr;110(4):300-302. doi: 10.5935/abc.20180066. English, Portuguese. No abstract available.


Thromboembolic findings in patients with heart failure at autopsy.

de Macedo IS, Dinardi LFL, Pereira TV, de Almeida LKR, Barbosa TS, Benvenuti LA, Ayub-Ferreira SM, Bocchi EA, Issa VS.

Cardiovasc Pathol. 2018 Jul - Aug;35:23-28. doi: 10.1016/j.carpath.2018.04.004. Epub 2018 Apr 13.


Cost-Effectiveness Benefits of a Disease Management Program:The REMADHE Trial Results.

Bocchi EA, da Cruz FDD, BrandÃo SM, Issa V, Ayub-Ferreira SM, la Rocca HB, Wijk SS.

J Card Fail. 2018 Oct;24(10):627-637. doi: 10.1016/j.cardfail.2018.04.008. Epub 2018 Apr 30.


Impact of Delayed Whole Blood Processing Time on Plasma Levels of miR- 1 and miR-423-5p up to 24 Hours.

Borges DP, Cunha-Neto E, Bocchi EA, Rigaud VOC.

Microrna. 2018;7(2):115-119. doi: 10.2174/2211536607666180322093119.


Carvedilol for Prevention of Chemotherapy-Related Cardiotoxicity: The CECCY Trial.

Avila MS, Ayub-Ferreira SM, de Barros Wanderley MR Jr, das Dores Cruz F, Gonçalves Brandão SM, Rigaud VOC, Higuchi-Dos-Santos MH, Hajjar LA, Kalil Filho R, Hoff PM, Sahade M, Ferrari MSM, de Paula Costa RL, Mano MS, Bittencourt Viana Cruz CB, Abduch MC, Lofrano Alves MS, Guimaraes GV, Issa VS, Bittencourt MS, Bocchi EA.

J Am Coll Cardiol. 2018 May 22;71(20):2281-2290. doi: 10.1016/j.jacc.2018.02.049. Epub 2018 Mar 11.


Clinical findings and prognosis of patients hospitalized for acute decompensated heart failure: Analysis of the influence of Chagas etiology and ventricular function.

Terhoch CB, Moreira HF, Ayub-Ferreira SM, Conceição-Souza GE, Salemi VMC, Chizzola PR, Oliveira MT Jr, Lage SHG, Bocchi EA, Issa VS.

PLoS Negl Trop Dis. 2018 Feb 12;12(2):e0006207. doi: 10.1371/journal.pntd.0006207. eCollection 2018 Feb.


Utility and quality-adjusted life-years in coronary artery disease: Five-year follow-up of the MASS II trial.

Brandão SMG, Hueb W, Ju YT, Lima ACP, Polanczyk CA, Cruz LN, Garcia RMR, Takiuti ME, Bocchi EA.

Medicine (Baltimore). 2017 Dec;96(50):e9113. doi: 10.1097/MD.0000000000009113.


Safety profile and efficacy of ivabradine in heart failure due to Chagas heart disease: a post hoc analysis of the SHIFT trial.

Bocchi EA, Rassi S, Guimarães GV; Argentina, Chile, and Brazil SHIFT Investigators.

ESC Heart Fail. 2018 Jun;5(3):249-256. doi: 10.1002/ehf2.12240. Epub 2017 Dec 20.


Chronic Chagas Heart Disease Management: From Etiology to Cardiomyopathy Treatment.

Bocchi EA, Bestetti RB, Scanavacca MI, Cunha Neto E, Issa VS.

J Am Coll Cardiol. 2017 Sep 19;70(12):1510-1524. doi: 10.1016/j.jacc.2017.08.004. Review.


Long-term Results of a Cardiology Postgraduate Program.

Bocchi EA, Borges DP, Rigaud VO.

Arq Bras Cardiol. 2017 Jun;108(6):491-500. doi: 10.5935/abc.20170083. English, Portuguese. No abstract available.


Decreased glycolytic metabolism in non-compaction cardiomyopathy by 18F-fluoro-2-deoxyglucose positron emission tomography: new insights into pathophysiological mechanisms and clinical implications.

Tavares de Melo MD, Giorgi MCP, Assuncao AN Jr, Dantas RN Jr, Araujo Filho JA, Parga Filho JR, Bierrenbach ALS, de Lima CR, Soares J Jr, Meneguetti JC, Mady C, Hajjar LA, Kalil Filho R, Bocchi EA, Salemi VMC.

Eur Heart J Cardiovasc Imaging. 2017 May 1;18(8):915-921. doi: 10.1093/ehjci/jex036.


Inflammatory biomarkers and effect of exercise on functional capacity in patients with heart failure: Insights from a randomized clinical trial.

Fernandes-Silva MM, Guimarães GV, Rigaud VO, Lofrano-Alves MS, Castro RE, de Barros Cruz LG, Bocchi EA, Bacal F.

Eur J Prev Cardiol. 2017 May;24(8):808-817. doi: 10.1177/2047487317690458. Epub 2017 Jan 30.


Diagnostic discrepancies in clinical practice: An autopsy study in patients with heart failure.

Issa VS, Dinardi LF, Pereira TV, de Almeida LK, Barbosa TS, Benvenutti LA, Ayub-Ferreira SM, Bocchi EA.

Medicine (Baltimore). 2017 Jan;96(4):e5978. doi: 10.1097/MD.0000000000005978.


Circulating miR-1 as a potential biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients.

Rigaud VO, Ferreira LR, Ayub-Ferreira SM, Ávila MS, Brandão SM, Cruz FD, Santos MH, Cruz CB, Alves MS, Issa VS, Guimarães GV, Cunha-Neto E, Bocchi EA.

Oncotarget. 2017 Jan 24;8(4):6994-7002. doi: 10.18632/oncotarget.14355.


Neurohumoral and Endothelial Responses to Heated Water-Based Exercise in Resistant Hypertensive Patients.

Cruz LG, Bocchi EA, Grassi G, Guimaraes GV.

Circ J. 2017 Feb 24;81(3):339-345. doi: 10.1253/circj.CJ-16-0870. Epub 2016 Dec 29.


Impact of Exhaled Breath Acetone in the Prognosis of Patients with Heart Failure with Reduced Ejection Fraction (HFrEF). One Year of Clinical Follow-up.

Marcondes-Braga FG, Batista GL, Gutz IG, Saldiva PH, Mangini S, Issa VS, Ayub-Ferreira SM, Bocchi EA, Pereira AC, Bacal F.

PLoS One. 2016 Dec 28;11(12):e0168790. doi: 10.1371/journal.pone.0168790. eCollection 2016.


Sleep-Disordered Breathing Exacerbates Muscle Vasoconstriction and Sympathetic Neural Activation in Patients with Systolic Heart Failure.

Lobo DM, Trevizan PF, Toschi-Dias E, Oliveira PA, Piveta RB, Almeida DR, Mady C, Bocchi EA, Lorenzi-Filho G, Middlekauff HR, Negrão CE.

Circ Heart Fail. 2016 Nov;9(11). pii: e003065. doi: 10.1161/CIRCHEARTFAILURE.116.003065.


Control of sinus tachycardia as an additional therapy in patients with decompensated heart failure (CONSTATHE-DHF): A randomized, double-blind, placebo-controlled trial.

Lofrano-Alves MS, Issa VS, Biselli B, Chizzola P, Ayub-Ferreira SM, Bocchi EA.

J Heart Lung Transplant. 2016 Oct;35(10):1260-1264. doi: 10.1016/j.healun.2016.06.005. Epub 2016 Jun 7. No abstract available.


Systemic effects of controlled exposure to diesel exhaust: a meta-analysis from randomized controlled trials.

Vieira JL, Macedo FY, Benjo AM, Guimarães GV, Contreras JP, Bocchi EA.

Ann Med. 2017 Mar;49(2):165-175. doi: 10.1080/07853890.2016.1252054. Epub 2016 Nov 18.


Diretriz de Assistência Circulatória Mecânica da Sociedade Brasileira de Cardiologia.

Ayub-Ferreira SM, Souza JD Neto, Almeida DR, Biselli B, Avila MS, Colafranceschi AS, Stefanello B, Carvalho BM, Polanczyk CA, Galantini DR, Bocchi EA, Chamlian EG, Hojaij EM, Gaiotto FA, Pinton FA, Jatene FB, Ramires F, Atik FA, Figueira F, Bacal F, Galas F, Brito FS, Conceição-Souza GE, Ribeiro G, Ja P Jr, Souza JM, Rossi JM Neto, Lima J, Mejía JC, Fernandes JR, Baumworcel L, Moura L, Hajjar LA, Beck-da-Silva L, Rohde L, Seguro L, Pinheiro ML, Park M, Fernandes MR, Montera MW, Alves M, Mrb W Jr, Hossne N, Fernandes P, Lemos P, Schneidewind RO, Uchoa RB, Honorato R, Mangini S, Falcão S, Lopes S, Strabelli T, Guimarães T, Campanili T, Issa VS.

Arq Bras Cardiol. 2016 Aug;107(2 Suppl 2):1-33. doi: 10.5935/abc.20160128. Portuguese. No abstract available.


Reply: Bad Air Revisited.

Vieira JL, Guimarães GV, Bocchi EA.

JACC Heart Fail. 2016 Jun;4(6):517-8. doi: 10.1016/j.jchf.2016.02.014. No abstract available.


Functional Class in Children with Idiopathic Dilated Cardiomyopathy. A pilot Study.

Tavares AC, Bocchi EA, Guimarães GV.

Arq Bras Cardiol. 2016 Jun;106(6):502-9. doi: 10.5935/abc.20160066. Epub 2016 May 6. English, Portuguese.


Effects of reducing exposure to air pollution on submaximal cardiopulmonary test in patients with heart failure: Analysis of the randomized, double-blind and controlled FILTER-HF trial.

Vieira JL, Guimaraes GV, de Andre PA, Saldiva PH, Bocchi EA.

Int J Cardiol. 2016 Jul 15;215:92-7. doi: 10.1016/j.ijcard.2016.04.071. Epub 2016 Apr 13.


Comment on "MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac Dysfunction".

Oliveira-Carvalho V, Bocchi EA.

Oxid Med Cell Longev. 2016;2016:7939626. doi: 10.1155/2016/7939626. Epub 2016 Feb 7. No abstract available.


Respiratory Filter Reduces the Cardiovascular Effects Associated With Diesel Exhaust Exposure: A Randomized, Prospective, Double-Blind, Controlled Study of Heart Failure: The FILTER-HF Trial.

Vieira JL, Guimaraes GV, de Andre PA, Cruz FD, Saldiva PH, Bocchi EA.

JACC Heart Fail. 2016 Jan;4(1):55-64. doi: 10.1016/j.jchf.2015.07.018.


Postexercise Hypotension after Heart Transplant: Water- versus Land-Based Exercise.

Castro RE, Guimarães GV, Da Silva JM, Bocchi EA, Ciolac EG.

Med Sci Sports Exerc. 2016 May;48(5):804-10. doi: 10.1249/MSS.0000000000000846.


Role of Trimetazidine in Ischemic Preconditioning in Patients With Symptomatic Coronary Artery Disease.

Costa LM, Rezende PC, Garcia RM, Uchida AH, Seguro LF, Scudeler TL, Bocchi EA, Krieger JE, Hueb W, Ramires JA, Filho RK.

Medicine (Baltimore). 2015 Aug;94(33):e1161. doi: 10.1097/MD.0000000000001161.


Reverse auction: a potential strategy for reduction of pharmacological therapy cost.

Brandão SM, Issa VS, Ayub-Ferreira SM, Storer S, Gonçalves BG, Santos VG, Carvas Junior N, Guimarães GV, Bocchi EA.

Arq Bras Cardiol. 2015 Sep;105(3):265-75. doi: 10.5935/abc.20150076. Epub 2015 Jul 21. English, Portuguese.


Circulating mir-208a fails as a biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients.

Oliveira-Carvalho V, Ferreira LR, Bocchi EA.

J Appl Toxicol. 2015 Sep;35(9):1071-2. doi: 10.1002/jat.3185. Epub 2015 Jun 5. No abstract available.


Effect of Combining Ivabradine and β-Blockers: Focus on the Use of Carvedilol in the SHIFT Population.

Bocchi EA, Böhm M, Borer JS, Ford I, Komajda M, Swedberg K, Tavazzi L; SHIFT investigators.

Cardiology. 2015;131(4):218-24. doi: 10.1159/000380812. Epub 2015 May 12.


Left ventricular assist device followed by heart transplantation.

Biselli B, Ayub-Ferreira SM, Avila MS, Gaiotto FA, Jatene FB, Bocchi EA.

Arq Bras Cardiol. 2015 Mar;104(3):e22-4. doi: 10.5935/abc.20140198. Epub 2015 Mar 1. English, Portuguese. No abstract available.


Determinants of peak VO2 in heart transplant recipients.

Oliveira Carvalho V, Guimarães GV, Vieira ML, Catai AM, Oliveira-Carvalho V, Ayub-Ferreira SM, Bocchi EA.

Rev Bras Cir Cardiovasc. 2015 Jan-Mar;30(1):9-15. doi: 10.5935/1678-9741.20140055. Erratum in: Rev Bras Cir Cardiovasc. 2015 Mar-Apr;30(2):287. Campos-Vieira, Marcelo Luiz [corrected to Vieira, Marcelo Luiz Campos].


Exercise training improves ambulatory blood pressure but not arterial stiffness in heart transplant recipients.

Pascoalino LN, Ciolac EG, Tavares AC, Castro RE, Ayub-Ferreira SM, Bacal F, Issa VS, Bocchi EA, Guimarães GV.

J Heart Lung Transplant. 2015 May;34(5):693-700. doi: 10.1016/j.healun.2014.11.013. Epub 2014 Nov 14.


Infectious agents and inflammation in donated hearts and dilated cardiomyopathies related to cardiovascular diseases, Chagas' heart disease, primary and secondary dilated cardiomyopathies.

Mangini S, Higuchi Mde L, Kawakami JT, Reis MM, Ikegami RN, Palomino SA, Pomerantzeff PM, Fiorelli AI, Marcondes-Braga FG, Bacal F, Ferreira SM, Issa VS, Souza GE, Chizzola PR, Bocchi EA.

Int J Cardiol. 2015 Jan 15;178:55-62. doi: 10.1016/j.ijcard.2014.10.133. Epub 2014 Oct 23.


Prescribing and Regulating Exercise with RPE after Heart Transplant: A Pilot Study.

Ciolac EG, Castro RE, Greve JM, Bacal F, Bocchi EA, Guimarães GV.

Med Sci Sports Exerc. 2015 Jul;47(7):1321-7. doi: 10.1249/MSS.0000000000000553.


Myocardial gene expression of T-bet, GATA-3, Ror-γt, FoxP3, and hallmark cytokines in chronic Chagas disease cardiomyopathy: an essentially unopposed TH1-type response.

Nogueira LG, Santos RH, Fiorelli AI, Mairena EC, Benvenuti LA, Bocchi EA, Stolf NA, Kalil J, Cunha-Neto E.

Mediators Inflamm. 2014;2014:914326. doi: 10.1155/2014/914326. Epub 2014 Jul 24.


Immunohistochemical quantification of inflammatory cells in endomyocardial biopsy fragments after heart transplantation: a new potential method to improve the diagnosis of rejection after heart transplantation.

Bocchi EA, Tanigawa RY, Brandão SM, Cruz F, Issa V, Ayub-Ferreira S, Chizzola P, Souza G, Fiorelli AI, Bacal F, Pomerantzeff PM, Honorato R, Lourenço-Filho D, Guimarães G, Benvenuti LA.

Transplant Proc. 2014 Jun;46(5):1489-96. doi: 10.1016/j.transproceed.2013.12.062.


MicroRNAs miR-1, miR-133a, miR-133b, miR-208a and miR-208b are dysregulated in Chronic Chagas disease Cardiomyopathy.

Ferreira LR, Frade AF, Santos RH, Teixeira PC, Baron MA, Navarro IC, Benvenuti LA, Fiorelli AI, Bocchi EA, Stolf NA, Chevillard C, Kalil J, Cunha-Neto E.

Int J Cardiol. 2014 Aug 20;175(3):409-17. doi: 10.1016/j.ijcard.2014.05.019. Epub 2014 May 17.


NHETS - Necropsy Heart Transplantation Study.

Valette TN, Ayub-Ferreira SM, Benvenuti LA, Issa VS, Bacal F, Chizzola PR, Souza GE, Fiorelli AI, Santos RH, Bocchi EA.

Arq Bras Cardiol. 2014 May;102(5):505-9. Epub 2014 Apr 17. English, Portuguese.

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