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Items: 50

1.

Chemical genomic screening of a Saccharomyces cerevisiae genomewide mutant collection reveals genes required for defense against four antimicrobial peptides derived from proteins found in human saliva.

Lis M, Bhatt S, Schoenly NE, Lee AY, Nislow C, Bobek LA.

Antimicrob Agents Chemother. 2013 Feb;57(2):840-7. doi: 10.1128/AAC.01439-12. Epub 2012 Dec 3.

3.

Antimicrobial peptide MUC7 12-mer activates the calcium/calcineurin pathway in Candida albicans.

Lis M, Liu TT, Barker KS, Rogers PD, Bobek LA.

FEMS Yeast Res. 2010 Aug 1;10(5):579-86. doi: 10.1111/j.1567-1364.2010.00638.x. Epub 2010 May 29.

4.

Exploring the mode of action of antimicrobial peptide MUC7 12-mer by fitness profiling of Saccharomyces cerevisiae genomewide mutant collection.

Lis M, Fuss JR, Bobek LA.

Antimicrob Agents Chemother. 2009 Sep;53(9):3762-9. doi: 10.1128/AAC.00668-09. Epub 2009 Jul 13.

5.

Proteomic and metabolic characterization of a Candida albicans mutant resistant to the antimicrobial peptide MUC7 12-mer.

Lis M, Bobek LA.

FEMS Immunol Med Microbiol. 2008 Oct;54(1):80-91. doi: 10.1111/j.1574-695X.2008.00450.x. Epub 2008 Aug 1.

6.

A comparative analysis of bone formation induced by human demineralized freeze-dried bone and enamel matrix derivative in rat calvaria critical-size bone defects.

Intini G, Andreana S, Buhite RJ, Bobek LA.

J Periodontol. 2008 Jul;79(7):1217-24. doi: 10.1902/jop.2008.070435 .

PMID:
18597604
7.

Factors affecting antimicrobial activity of MUC7 12-mer, a human salivary mucin-derived peptide.

Wei GX, Campagna AN, Bobek LA.

Ann Clin Microbiol Antimicrob. 2007 Nov 11;6:14.

8.

Calcium sulfate and platelet-rich plasma make a novel osteoinductive biomaterial for bone regeneration.

Intini G, Andreana S, Intini FE, Buhite RJ, Bobek LA.

J Transl Med. 2007 Mar 7;5:13.

9.

Functional analysis of human MUC7 mucin gene 5'-flanking region in lung epithelial cells.

Li S, Bobek LA.

Am J Respir Cell Mol Biol. 2006 Nov;35(5):593-601. Epub 2006 Jun 15.

10.

Effect of MUC7 peptides on the growth of bacteria and on Streptococcus mutans biofilm.

Wei GX, Campagna AN, Bobek LA.

J Antimicrob Chemother. 2006 Jun;57(6):1100-9. Epub 2006 Apr 4.

PMID:
16595638
11.

Modulation of MUC7 mucin expression by exogenous factors in airway cells in vitro and in vivo.

Li S, Intini G, Bobek LA.

Am J Respir Cell Mol Biol. 2006 Jul;35(1):95-102. Epub 2006 Mar 2.

13.

In vitro synergic antifungal effect of MUC7 12-mer with histatin-5 12-mer or miconazole.

Wei GX, Bobek LA.

J Antimicrob Chemother. 2004 May;53(5):750-8. Epub 2004 Apr 8.

PMID:
15073161
14.

Efficacy of human salivary mucin MUC7-derived peptide and histatin 5 in a murine model of candidiasis.

Intini G, Aguirre A, Bobek LA.

Int J Antimicrob Agents. 2003 Dec;22(6):594-600.

PMID:
14659657
15.

Human salivary MUC7 mucin peptides: effect of size, charge and cysteine residues on antifungal activity.

Situ H, Wei G, Smith CJ, Mashhoon S, Bobek LA.

Biochem J. 2003 Oct 1;375(Pt 1):175-82.

16.
17.

Divergent solid-phase synthesis and candidacidal activity of MUC7 D1, a 51-residue histidine-rich N-terminal domain of human salivary mucin MUC7.

Satyanarayana J, Situ H, Narasimhamurthy S, Bhayani N, Bobek LA, Levine MJ.

J Pept Res. 2000 Nov;56(5):275-82.

PMID:
11095181
18.

Role of alpha-helical conformation of histatin-5 in candidacidal activity examined by proline variants.

Situ H, Balasubramanian SV, Bobek LA.

Biochim Biophys Acta. 2000 Jul 26;1475(3):377-82.

PMID:
10913839
19.
21.

Tissue-specific expression of human salivary mucin gene, MUC7, in transgenic mice.

Bobek LA, Li H, Rojstaczer N, Jones C, Gross KW, Levine MJ.

Transgenic Res. 1998 May;7(3):195-204.

PMID:
10461391
23.
24.

Construction and characterization of human salivary histatin-5 multimers.

Situ H, Tsai H, Bobek LA.

J Dent Res. 1999 Feb;78(2):690-8.

PMID:
10029468
25.

Human salivary histatins: promising anti-fungal therapeutic agents.

Tsai H, Bobek LA.

Crit Rev Oral Biol Med. 1998;9(4):480-97. Review.

PMID:
9825223
26.

Transfection of COS cells with human cystatin cDNA and its effect on HSV-1 replication.

Weaver-Hiltke TR, Bobek LA.

Ann N Y Acad Sci. 1998 Apr 15;842:204-8. No abstract available.

PMID:
9599312
27.

Human salivary histatin-5 exerts potent fungicidal activity against Cryptococcus neoformans.

Tsai H, Bobek LA.

Biochim Biophys Acta. 1997 Oct 20;1336(3):367-9.

PMID:
9367163
29.

MUC7 gene expression and genetic polymorphism.

Biesbrock AR, Bobek LA, Levine MJ.

Glycoconj J. 1997 Jun;14(4):415-22.

PMID:
9249138
30.

Candidacidal activity of recombinant human salivary histatin-5 and variants.

Tsai H, Raj PA, Bobek LA.

Infect Immun. 1996 Dec;64(12):5000-7.

31.

Preliminary X-ray crystallographic analysis of human salivary cystatin.

Ramasubbu N, Weaver T, Tseng CC, Bobek LA, Levine MJ.

Acta Crystallogr D Biol Crystallogr. 1996 Jul 1;52(Pt 4):869-70.

PMID:
15299654
32.

Structure and chromosomal localization of the human salivary mucin gene, MUC7.

Bobek LA, Liu J, Sait SN, Shows TB, Bobek YA, Levine MJ.

Genomics. 1996 Feb 1;31(3):277-82.

PMID:
8838308
33.

Biological activities and secondary structures of variant forms of human salivary cystatin SN produced in Escherichia coli.

Bobek LA, Ramasubbu N, Wang X, Weaver TR, Levine MJ.

Gene. 1994 Dec 30;151(1-2):303-8.

PMID:
7828895
34.
35.

Efficient production of biologically active human salivary cystatins in Escherichia coli.

Bobek LA, Wang X, Levine MJ.

Gene. 1993 Jan 30;123(2):203-10.

PMID:
8428660
36.

Expression of human salivary histatin and cystatin/histatin chimeric cDNAs in Escherichia coli.

Bobek LA, Tsai H, Levine MJ.

Crit Rev Oral Biol Med. 1993;4(3-4):581-90.

PMID:
8374011
37.

Structural features of the low-molecular-mass human salivary mucin.

Reddy MS, Bobek LA, Haraszthy GG, Biesbrock AR, Levine MJ.

Biochem J. 1992 Oct 15;287 ( Pt 2):639-43.

38.

Identification and analysis of the gap region in the 23S ribosomal RNA from Actinobacillus actinomycetemcomitans.

Haraszthy VI, Sunday GJ, Bobek LA, Motley TS, Preus H, Zambon JJ.

J Dent Res. 1992 Sep;71(9):1561-8.

PMID:
1381732
39.

Cystatins--inhibitors of cysteine proteinases.

Bobek LA, Levine MJ.

Crit Rev Oral Biol Med. 1992;3(4):307-32. Review. Erratum in: Crit Rev Oral Biol Med 1993;4(2):251.

PMID:
1391414
40.
41.
42.
43.

The gene family encoding eggshell proteins of Schistosoma japonicum.

Henkle KJ, Cook GA, Foster LA, Engman DM, Bobek LA, Cain GD, Donelson JE.

Mol Biochem Parasitol. 1990 Aug;42(1):69-82.

PMID:
2172818
44.

Schistosoma haematobium: analysis of eggshell protein genes and their expression.

Bobek LA, LoVerde PT, Rekosh DM.

Exp Parasitol. 1989 Jan;68(1):17-30.

PMID:
2917627
45.

Developmentally regulated gene expression in Schistosoma.

LoVerde PT, Rekosh DM, Bobek LA.

Exp Parasitol. 1989 Jan;68(1):116-20. Review. No abstract available.

PMID:
2645161
46.
47.

Organization of the ribosomal RNA genes in Schistosoma mansoni.

van Keulen H, Loverde PT, Bobek LA, Rekosh DM.

Mol Biochem Parasitol. 1985 May;15(2):215-30.

PMID:
4010707
48.

There are at least two yeast viral double-stranded RNAs of the same size: an explanation for viral exclusion.

Field LJ, Bobek LA, Brennan VE, Reilly JD, Bruenn JA.

Cell. 1982 Nov;31(1):193-200.

PMID:
6760984
49.

Cloning of cDNA to a yeast viral double-stranded RNA and comparison of three viral RNAs.

Bobek LA, Bruenn JA, Field LJ, Gross KW.

Gene. 1982 Sep;19(2):225-30.

PMID:
6757056
50.

Yeast deRNA viral transcriptase pause products: identification of the transcript strand.

Brennan VE, Bobek LA, Bruenn JA.

Nucleic Acids Res. 1981 Oct 10;9(19):5049-59.

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