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Items: 1 to 50 of 102

1.

SerpinA3 in the Early Recognition of Acute Kidney Injury to Chronic Kidney Disease (CKD) transition in the rat and its Potentiality in the Recognition of Patients with CKD.

Sánchez-Navarro A, Mejía-Vilet JM, Pérez-Villalva R, Carrillo-Pérez DL, Marquina-Castillo B, Gamba G, Bobadilla NA.

Sci Rep. 2019 Jul 17;9(1):10350. doi: 10.1038/s41598-019-46601-1.

2.

Spironolactone reduces oxidative stress in living donor kidney transplantation: a randomized controlled trial.

Morales-Buenrostro LE, Ortega-Trejo JA, Pérez-Villalva R, Marino LA, González-Bobadilla Y, Juárez H, Zamora-Mejía FM, González N, Espinoza R, Barrera-Chimal J, Bobadilla NA.

Am J Physiol Renal Physiol. 2019 Sep 1;317(3):F519-F528. doi: 10.1152/ajprenal.00606.2018. Epub 2019 Jun 26.

PMID:
31241992
3.

Reduced endothelial nitric oxide synthase activation contributes to cardiovascular injury during chronic kidney disease progression.

Amador-Martínez I, Pérez-Villalva R, Uribe N, Cortés-González C, Bobadilla NA, Barrera-Chimal J.

Am J Physiol Renal Physiol. 2019 Aug 1;317(2):F275-F285. doi: 10.1152/ajprenal.00020.2019. Epub 2019 May 22.

PMID:
31116605
4.

Pirfenidone prevents acute kidney injury in the rat.

Lima-Posada I, Fontana F, Pérez-Villalva R, Berman-Parks N, Bobadilla NA.

BMC Nephrol. 2019 May 8;20(1):158. doi: 10.1186/s12882-019-1364-4.

5.

Integrative View of the Mechanisms that Induce Acute Kidney Injury and its Transition to Chronic Kidney Disease.

García-Ortuño LE, Bobadilla NA.

Rev Invest Clin. 2018;70(6):261-268. doi: 10.24875/RIC.18002546. Review.

6.

Delayed spironolactone administration prevents the transition from acute kidney injury to chronic kidney disease through improving renal inflammation.

Barrera-Chimal J, Rocha L, Amador-Martínez I, Pérez-Villalva R, González R, Cortés-González C, Uribe N, Ramírez V, Berman N, Gamba G, Bobadilla NA.

Nephrol Dial Transplant. 2019 May 1;34(5):794-801. doi: 10.1093/ndt/gfy246.

PMID:
30107561
7.

The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway.

Bazúa-Valenti S, Rojas-Vega L, Castañeda-Bueno M, Barrera-Chimal J, Bautista R, Cervantes-Pérez LG, Vázquez N, Plata C, Murillo-de-Ozores AR, González-Mariscal L, Ellison DH, Riccardi D, Bobadilla NA, Gamba G.

J Am Soc Nephrol. 2018 Jul;29(7):1838-1848. doi: 10.1681/ASN.2017111155. Epub 2018 May 30.

8.

Inactivation of SPAK kinase reduces body weight gain in mice fed a high-fat diet by improving energy expenditure and insulin sensitivity.

Torre-Villalvazo I, Cervantes-Pérez LG, Noriega LG, Jiménez JV, Uribe N, Chávez-Canales M, Tovar-Palacio C, Marfil-Garza BA, Torres N, Bobadilla NA, Tovar AR, Gamba G.

Am J Physiol Endocrinol Metab. 2018 Jan 1;314(1):E53-E65. doi: 10.1152/ajpendo.00108.2017. Epub 2017 Oct 24.

9.

Geraniin is a diuretic by inhibiting the Na+-K+-2Cl- cotransporter NKCC2.

Moreno E, Gayosso JA, Montejano JR, Almaguer G, Vázquez N, Cruz C, Mercado A, Bobadilla NA, Gamba G, Sierra A, Ramírez V.

Am J Physiol Renal Physiol. 2018 Feb 1;314(2):F240-F250. doi: 10.1152/ajprenal.00221.2017. Epub 2017 Oct 18.

10.

Gender Differences in the Acute Kidney Injury to Chronic Kidney Disease Transition.

Lima-Posada I, Portas-Cortés C, Pérez-Villalva R, Fontana F, Rodríguez-Romo R, Prieto R, Sánchez-Navarro A, Rodríguez-González GL, Gamba G, Zambrano E, Bobadilla NA.

Sci Rep. 2017 Sep 25;7(1):12270. doi: 10.1038/s41598-017-09630-2.

11.

Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II.

Cervantes-Perez LG, Castaneda-Bueno M, Jimenez JV, Vazquez N, Rojas-Vega L, Alessi DR, Bobadilla NA, Gamba G.

J Hypertens. 2018 Feb;36(2):361-367. doi: 10.1097/HJH.0000000000001554.

12.

Randomized Controlled Trial of Mineralocorticoid Receptor Blockade in Children with Chronic Kidney Allograft Nephropathy.

Medeiros M, Velásquez-Jones L, Hernández AM, Ramón-García G, Valverde S, Fuentes Y, Vargas A, Patiño M, Pérez-Villalva R, Ortega-Trejo JA, Barrera-Chimal J, Bobadilla NA.

Clin J Am Soc Nephrol. 2017 Aug 7;12(8):1291-1300. doi: 10.2215/CJN.05300516. Epub 2017 May 23.

13.

HSP72 is an early biomarker to detect cisplatin and acetaminophen nephrotoxicity.

Pérez-Villalva R, Barrera-Chimal J, Aguilar-Carrasco JC, Lima-Posada I, Cruz C, Ramírez V, González-Bobadilla Y, Uribe N, Trumper L, Bobadilla NA.

Biomarkers. 2017 Sep;22(6):548-556. doi: 10.1080/1354750X.2017.1315616. Epub 2017 Apr 19.

PMID:
28393561
14.

Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone Protects Against Acute Kidney Injury-Mediated Chronic Kidney Disease: Role of Oxidative Stress.

Lattenist L, Lechner SM, Messaoudi S, Le Mercier A, El Moghrabi S, Prince S, Bobadilla NA, Kolkhof P, Jaisser F, Barrera-Chimal J.

Hypertension. 2017 May;69(5):870-878. doi: 10.1161/HYPERTENSIONAHA.116.08526. Epub 2017 Mar 20.

PMID:
28320854
15.

Mineralocorticoid Receptor Antagonism: A Promising Therapeutic Approach to Treat Ischemic AKI.

Barrera-Chimal J, Bobadilla NA, Jaisser F.

Nephron. 2016;134(1):10-3. doi: 10.1159/000445080. Epub 2016 Mar 19. Review.

16.

Kidney function in sugarcane cutters in Nicaragua--A longitudinal study of workers at risk of Mesoamerican nephropathy.

Wesseling C, Aragón A, González M, Weiss I, Glaser J, Bobadilla NA, Roncal-Jiménez C, Correa-Rotter R, Johnson RJ, Barregard L.

Environ Res. 2016 May;147:125-32. doi: 10.1016/j.envres.2016.02.002. Epub 2016 Feb 8.

17.

Sub-chronic exposure to fluoride impacts the response to a subsequent nephrotoxic treatment with gentamicin.

Cárdenas-González M, Jacobo Estrada T, Rodríguez-Muñoz R, Barrera-Chimal J, Bobadilla NA, Barbier OC, Del Razo LM.

J Appl Toxicol. 2016 Feb;36(2):309-19. doi: 10.1002/jat.3186. Epub 2015 Jun 17.

PMID:
26779593
18.

Changes in milk composition in obese rats consuming a high-fat diet.

Bautista CJ, Montaño S, Ramirez V, Morales A, Nathanielsz PW, Bobadilla NA, Zambrano E.

Br J Nutr. 2016 Feb 14;115(3):538-46. doi: 10.1017/S0007114515004547. Epub 2015 Nov 26.

PMID:
26608475
19.

AT1 receptor antagonism before ischemia prevents the transition of acute kidney injury to chronic kidney disease.

Rodríguez-Romo R, Benítez K, Barrera-Chimal J, Pérez-Villalva R, Gómez A, Aguilar-León D, Rangel-Santiago JF, Huerta S, Gamba G, Uribe N, Bobadilla NA.

Kidney Int. 2016 Feb;89(2):363-73.

PMID:
26509589
20.

Heat shock protein 72 (Hsp72) specific induction and temporal stability in urine samples as a reliable biomarker of acute kidney injury (AKI).

Ortega-Trejo JA, Pérez-Villalva R, Barrera-Chimal J, Carrillo-Pérez DL, Morales-Buenrostro LE, Gamba G, Flores ME, Bobadilla NA.

Biomarkers. 2015;20(6-7):453-9. doi: 10.3109/1354750X.2015.1096305. Epub 2015 Oct 21.

PMID:
26488549
21.

Mild ischemic injury leads to long-term alterations in the kidney: amelioration by spironolactone administration.

Barrera-Chimal J, Pérez-Villalva R, Ortega JA, Sánchez A, Rodríguez-Romo R, Durand M, Jaisser F, Bobadilla NA.

Int J Biol Sci. 2015 Jun 6;11(8):892-900. doi: 10.7150/ijbs.11729. eCollection 2015.

22.

The amniotic band syndrome in the rat is associated with the activation of transforming growth factor-β.

Romero-Valdovinos M, Galván-Montaño A, Olivo-Díaz A, Maravilla P, Bobadilla NA, Vadillo-Ortega F, Flisser A.

Am J Pathol. 2015 Aug;185(8):2076-82. doi: 10.1016/j.ajpath.2015.04.006. Epub 2015 Jun 6.

PMID:
26055209
23.

Epigenetic regulation in the acute kidney injury to chronic kidney disease transition.

Rodríguez-Romo R, Berman N, Gómez A, Bobadilla NA.

Nephrology (Carlton). 2015 Oct;20(10):736-743. doi: 10.1111/nep.12521. Review.

PMID:
26015167
24.

Antigen-induced airway hyperresponsiveness and obstruction is related to caveolin-1 expression in airway smooth muscle in a guinea pig asthma model.

Álvarez-Santos M, Ramos-Ramírez P, Gutiérrez-Aguilar F, Sánchez-Hernández S, Lascurain R, Olmos-Zuñiga R, Jasso-Victoria R, Bobadilla NA, Bazan-Perkins B.

Clin Transl Allergy. 2015 Mar 26;5:14. doi: 10.1186/s13601-015-0058-7. eCollection 2015.

25.

Ovarian hormones and prolactin increase renal NaCl cotransporter phosphorylation.

Rojas-Vega L, Reyes-Castro LA, Ramírez V, Bautista-Pérez R, Rafael C, Castañeda-Bueno M, Meade P, de Los Heros P, Arroyo-Garza I, Bernard V, Binart N, Bobadilla NA, Hadchouel J, Zambrano E, Gamba G.

Am J Physiol Renal Physiol. 2015 Apr 15;308(8):F799-808. doi: 10.1152/ajprenal.00447.2014. Epub 2015 Jan 13.

26.

Hsp72 is a novel biomarker to predict acute kidney injury in critically ill patients.

Morales-Buenrostro LE, Salas-Nolasco OI, Barrera-Chimal J, Casas-Aparicio G, Irizar-Santana S, Pérez-Villalva R, Bobadilla NA.

PLoS One. 2014 Oct 14;9(10):e109407. doi: 10.1371/journal.pone.0109407. eCollection 2014.

27.

Tubular urinary biomarkers do not identify aetiology of acute kidney injury in kidney transplant recipients.

Ramirez-Sandoval JC, Barrera-Chimal J, Simancas PE, Correa-Rotter R, Bobadilla NA, Morales-Buenrostro LE.

Nephrology (Carlton). 2014 Jun;19(6):352-8. doi: 10.1111/nep.12240.

PMID:
24666430
28.

Urinary neutrophil gelatinase-associated lipocalin predicts graft loss after acute kidney injury in kidney transplant.

Ramírez-Sandoval JC, Barrera-Chimal J, Simancas PE, Rojas-Montaño A, Correa-Rotter R, Bobadilla NA, Morales-Buenrostro LE.

Biomarkers. 2014 Feb;19(1):63-9. doi: 10.3109/1354750X.2013.867536. Epub 2013 Dec 11.

PMID:
24325180
29.

Intra-renal transfection of heat shock protein 90 alpha or beta (Hsp90α or Hsp90β) protects against ischemia/reperfusion injury.

Barrera-Chimal J, Pérez-Villalva R, Ortega JA, Uribe N, Gamba G, Cortés-González C, Bobadilla NA.

Nephrol Dial Transplant. 2014 Feb;29(2):301-12. doi: 10.1093/ndt/gft415. Epub 2013 Oct 28.

PMID:
24166465
30.

N-terminal serine dephosphorylation is required for KCC3 cotransporter full activation by cell swelling.

Melo Z, de los Heros P, Cruz-Rangel S, Vázquez N, Bobadilla NA, Pasantes-Morales H, Alessi DR, Mercado A, Gamba G.

J Biol Chem. 2013 Nov 1;288(44):31468-76. doi: 10.1074/jbc.M113.475574. Epub 2013 Sep 16.

31.

Proximal renal tubular injury in rats sub-chronically exposed to low fluoride concentrations.

Cárdenas-González MC, Del Razo LM, Barrera-Chimal J, Jacobo-Estrada T, López-Bayghen E, Bobadilla NA, Barbier O.

Toxicol Appl Pharmacol. 2013 Nov 1;272(3):888-94. doi: 10.1016/j.taap.2013.07.026. Epub 2013 Aug 7.

PMID:
23933529
32.

The authors reply.

Barrera-Chimal J, Bobadilla NA.

Kidney Int. 2013 Aug;84(2):415-6. doi: 10.1038/ki.2013.166. No abstract available.

33.

Mineralocorticoid receptor blockade reduced oxidative stress in renal transplant recipients: a double-blind, randomized pilot study.

Ojeda-Cervantes M, Barrera-Chimal J, Alberú J, Pérez-Villalva R, Morales-Buenrostro LE, Bobadilla NA.

Am J Nephrol. 2013;37(5):481-90. doi: 10.1159/000350539. Epub 2013 Apr 30.

PMID:
23635604
34.

[Is aldosterone a modulator of vascular tone?].

Sánchez-Pozos K, Bobadilla NA.

Rev Invest Clin. 2012 Nov-Dec;64(6 Pt 1):546-57. Review. Spanish.

PMID:
23513612
35.

Insulin increases the functional activity of the renal NaCl cotransporter.

Chávez-Canales M, Arroyo JP, Ko B, Vázquez N, Bautista R, Castañeda-Bueno M, Bobadilla NA, Hoover RS, Gamba G.

J Hypertens. 2013 Feb;31(2):303-11. doi: 10.1097/HJH.0b013e32835bbb83.

36.

Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury.

Barrera-Chimal J, Pérez-Villalva R, Rodríguez-Romo R, Reyna J, Uribe N, Gamba G, Bobadilla NA.

Kidney Int. 2013 Jan;83(1):93-103. doi: 10.1038/ki.2012.352. Epub 2012 Sep 26.

37.

Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process.

Castañeda-Bueno M, Cervantes-Pérez LG, Vázquez N, Uribe N, Kantesaria S, Morla L, Bobadilla NA, Doucet A, Alessi DR, Gamba G.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):7929-34. doi: 10.1073/pnas.1200947109. Epub 2012 May 1.

38.

Recovery from ischemic acute kidney injury by spironolactone administration.

Sánchez-Pozos K, Barrera-Chimal J, Garzón-Muvdi J, Pérez-Villalva R, Rodríguez-Romo R, Cruz C, Gamba G, Bobadilla NA.

Nephrol Dial Transplant. 2012 Aug;27(8):3160-9. doi: 10.1093/ndt/gfs014. Epub 2012 Apr 19.

PMID:
22516623
39.

Are recently reported biomarkers helpful for early and accurate diagnosis of acute kidney injury?

Barrera-Chimal J, Bobadilla NA.

Biomarkers. 2012 Aug;17(5):385-93. doi: 10.3109/1354750X.2012.680070. Epub 2012 Apr 19. Review.

PMID:
22515481
40.

WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family.

Pacheco-Alvarez D, Vázquez N, Castañeda-Bueno M, de-Los-Heros P, Cortes-González C, Moreno E, Meade P, Bobadilla NA, Gamba G.

Cell Physiol Biochem. 2012;29(1-2):291-302. doi: 10.1159/000337610. Epub 2012 Mar 1.

41.

Gene expression analysis reveals the cell cycle and kinetochore genes participating in ischemia reperfusion injury and early development in kidney.

Kim TM, Ramírez V, Barrera-Chimal J, Bobadilla NA, Park PJ, Vaidya VS.

PLoS One. 2011;6(9):e25679. doi: 10.1371/journal.pone.0025679. Epub 2011 Sep 28.

42.

The hyperpolarization-activated cyclic nucleotide-gated HCN2 channel transports ammonium in the distal nephron.

Carrisoza-Gaytán R, Rangel C, Salvador C, Saldaña-Meyer R, Escalona C, Satlin LM, Liu W, Zavilowitz B, Trujillo J, Bobadilla NA, Escobar LI.

Kidney Int. 2011 Oct;80(8):832-40. doi: 10.1038/ki.2011.230. Epub 2011 Jul 27.

43.

WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters.

Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP.

J Biol Chem. 2011 Aug 26;286(34):30171-80. doi: 10.1074/jbc.M111.222893. Epub 2011 Jul 6.

44.

Fibrinogen β-derived Bβ(15-42) peptide protects against kidney ischemia/reperfusion injury.

Krishnamoorthy A, Ajay AK, Hoffmann D, Kim TM, Ramirez V, Campanholle G, Bobadilla NA, Waikar SS, Vaidya VS.

Blood. 2011 Aug 18;118(7):1934-42. doi: 10.1182/blood-2011-02-338061. Epub 2011 Jun 17.

45.

Similar effects of all WNK3 variants on SLC12 cotransporters.

Cruz-Rangel S, Melo Z, Vázquez N, Meade P, Bobadilla NA, Pasantes-Morales H, Gamba G, Mercado A.

Am J Physiol Cell Physiol. 2011 Sep;301(3):C601-8. doi: 10.1152/ajpcell.00070.2011. Epub 2011 May 25.

46.

Hsp72 is an early and sensitive biomarker to detect acute kidney injury.

Barrera-Chimal J, Pérez-Villalva R, Cortés-González C, Ojeda-Cervantes M, Gamba G, Morales-Buenrostro LE, Bobadilla NA.

EMBO Mol Med. 2011 Jan;3(1):5-20. doi: 10.1002/emmm.201000105. Epub 2010 Dec 14.

47.

Rare mutations in SLC12A1 and SLC12A3 protect against hypertension by reducing the activity of renal salt cotransporters.

Acuña R, Martínez-de-la-Maza L, Ponce-Coria J, Vázquez N, Ortal-Vite P, Pacheco-Alvarez D, Bobadilla NA, Gamba G.

J Hypertens. 2011 Mar;29(3):475-83. doi: 10.1097/HJH.0b013e328341d0fd.

PMID:
21157372
48.

Opposite effect of Hsp90α and Hsp90β on eNOS ability to produce nitric oxide or superoxide anion in human embryonic kidney cells.

Cortes-González C, Barrera-Chimal J, Ibarra-Sánchez M, Gilbert M, Gamba G, Zentella A, Flores ME, Bobadilla NA.

Cell Physiol Biochem. 2010;26(4-5):657-68. doi: 10.1159/000322333. Epub 2010 Oct 29.

49.

A single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters.

Castañeda-Bueno M, Vázquez N, Bustos-Jaimes I, Hernández D, Rodríguez-Lobato E, Pacheco-Alvarez D, Cariño-Cortés R, Moreno E, Bobadilla NA, Gamba G.

Am J Physiol Renal Physiol. 2010 Nov;299(5):F1111-9. doi: 10.1152/ajprenal.00412.2010. Epub 2010 Aug 18.

50.

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies.

Vaidya VS, Ozer JS, Dieterle F, Collings FB, Ramirez V, Troth S, Muniappa N, Thudium D, Gerhold D, Holder DJ, Bobadilla NA, Marrer E, Perentes E, Cordier A, Vonderscher J, Maurer G, Goering PL, Sistare FD, Bonventre JV.

Nat Biotechnol. 2010 May;28(5):478-85. doi: 10.1038/nbt.1623.

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