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Items: 1 to 50 of 142

1.

Cancer cachexia in thoracic malignancy: a narrative review.

Kidd AC, Skrzypski M, Jamal-Hanjani M, Blyth KG.

Curr Opin Support Palliat Care. 2019 Dec;13(4):316-322. doi: 10.1097/SPC.0000000000000465.

PMID:
31592847
2.

Inter-observer variation in image interpretation and the prognostic importance of non-expansile lung in malignant pleural effusion.

Martin GA, Kidd AC, Tsim S, Halford P, Bibby A, Maskell NA, Blyth KG.

Respirology. 2019 Aug 21. doi: 10.1111/resp.13681. [Epub ahead of print]

PMID:
31433545
3.

Pre-EDIT: A Randomized Feasibility Trial of Elastance-Directed Intrapleural Catheter or Talc Pleurodesis in Malignant Pleural Effusion.

Martin GA, Tsim S, Kidd AC, Foster JE, McLoone P, Chalmers A, Blyth KG.

Chest. 2019 Jul 30. pii: S0012-3692(19)31384-4. doi: 10.1016/j.chest.2019.07.010. [Epub ahead of print]

PMID:
31374208
4.

A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing.

Hassan S, Purdie KJ, Wang J, Harwood CA, Proby CM, Pourreyron C, Mladkova N, Nagano A, Dhayade S, Athineos D, Caley M, Mannella V, Blyth K, Inman GJ, Leigh IM.

Int J Mol Sci. 2019 Jul 12;20(14). pii: E3428. doi: 10.3390/ijms20143428.

5.

Baseline predictors of negative and incomplete pleural cytology in patients with suspected pleural malignancy - Data supporting 'Direct to LAT' in selected groups.

Tsim S, Paterson S, Cartwright D, Fong CJ, Alexander L, Kelly C, Holme J, Evison M, Blyth KG.

Lung Cancer. 2019 Jul;133:123-129. doi: 10.1016/j.lungcan.2019.05.017. Epub 2019 May 16.

PMID:
31200818
6.

Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization.

Rudzka DA, Spennati G, McGarry DJ, Chim YH, Neilson M, Ptak A, Munro J, Kalna G, Hedley A, Moralli D, Green C, Mason S, Blyth K, Mullin M, Yin H, Olson MF.

J Cell Sci. 2019 May 31;132(11). pii: jcs224071. doi: 10.1242/jcs.224071.

7.

Loss of RAF kinase inhibitor protein is involved in myelomonocytic differentiation and aggravates RAS-driven myeloid leukemogenesis.

Caraffini V, Geiger O, Rosenberger A, Hatzl S, Perfler B, Berg JL, Lim C, Strobl H, Kashofer K, Schauer S, Beham-Schmid C, Hoefler G, Geissler K, Quehenberger F, Kolch W, Athineos D, Blyth K, Wölfler A, Sill H, Zebisch A.

Haematologica. 2019 May 16. pii: haematol.2018.209650. doi: 10.3324/haematol.2018.209650. [Epub ahead of print]

8.

Imaging in pleural mesothelioma: A review of the 14th International Conference of the International Mesothelioma Interest Group.

Armato SG 3rd, Francis RJ, Katz SI, Ak G, Opitz I, Gudmundsson E, Blyth KG, Gupta A.

Lung Cancer. 2019 Apr;130:108-114. doi: 10.1016/j.lungcan.2018.11.033. Epub 2018 Nov 28. Review.

PMID:
30885330
9.

Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.

Liko D, Mitchell L, Campbell KJ, Ridgway RA, Jones C, Dudek K, King A, Bryson S, Stevenson D, Blyth K, Strathdee D, Morton JP, Bird TG, Knight JRP, Willis AE, Sansom OJ.

Cell Death Differ. 2019 Dec;26(12):2535-2550. doi: 10.1038/s41418-019-0316-7. Epub 2019 Mar 11.

PMID:
30858608
10.

Author Correction: Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori.

Johnson SA, Ormsby MJ, McIntosh A, Tait SWG, Blyth K, Wall DM.

Cancer Gene Ther. 2019 Feb 20. doi: 10.1038/s41417-019-0086-x. [Epub ahead of print]

PMID:
30783214
11.

Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study.

Cunningham Y, Wyke S, Blyth KG, Rigg D, Macdonald S, Macleod U, Harrow S, Robb KA, Whitaker KL.

Psychooncology. 2019 Apr;28(4):718-725. doi: 10.1002/pon.5005. Epub 2019 Feb 12.

12.

Improving the metabolic fidelity of cancer models with a physiological cell culture medium.

Vande Voorde J, Ackermann T, Pfetzer N, Sumpton D, Mackay G, Kalna G, Nixon C, Blyth K, Gottlieb E, Tardito S.

Sci Adv. 2019 Jan 2;5(1):eaau7314. doi: 10.1126/sciadv.aau7314. eCollection 2019 Jan.

13.

Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels.

Novo D, Heath N, Mitchell L, Caligiuri G, MacFarlane A, Reijmer D, Charlton L, Knight J, Calka M, McGhee E, Dornier E, Sumpton D, Mason S, Echard A, Klinkert K, Secklehner J, Kruiswijk F, Vousden K, Macpherson IR, Blyth K, Bailey P, Yin H, Carlin LM, Morton J, Zanivan S, Norman JC.

Nat Commun. 2018 Nov 29;9(1):5069. doi: 10.1038/s41467-018-07339-y.

14.

Predicting survival following surgical resection of lung cancer using clinical and pathological variables: The development and validation of the LNC-PATH score.

Balata H, Foden P, Edwards T, Chaturvedi A, Elshafi M, Tempowski A, Teng B, Whittemore P, Blyth KG, Kidd A, Ellames D, Flint LA, Robson J, Teh E, Jones R, Batchelor T, Crosbie P, Booton R, Evison M.

Lung Cancer. 2018 Nov;125:29-34. doi: 10.1016/j.lungcan.2018.08.026. Epub 2018 Aug 31.

PMID:
30429034
15.

Somatic cancer genetics in the UK: real-world data from phase I of the Cancer Research UK Stratified Medicine Programme.

Lindsay CR, Shaw EC, Blackhall F, Blyth KG, Brenton JD, Chaturvedi A, Clarke N, Dick C, Evans TRJ, Hall G, Hanby AM, Harrison DJ, Johnston SRD, Mason MD, Morton D, Newton-Bishop J, Nicholson AG, Oien KA, Popat S, Rassl D, Sharpe R, Taniere P, Walker I, Wallace WA, West NP, Butler R, Gonzalez de Castro D, Griffiths M, Johnson PWM.

ESMO Open. 2018 Sep 5;3(6):e000408. doi: 10.1136/esmoopen-2018-000408. eCollection 2018.

16.

Correction: Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori.

Johnson SA, Ormsby MJ, McIntosh A, Tait SWG, Blyth K, Wall DM.

Cancer Gene Ther. 2018 Dec;25(11-12):339. doi: 10.1038/s41417-018-0047-9.

PMID:
30232385
17.

Providing safe and effective pleural medicine services in the UK: an aspirational statement from UK pleural physicians.

Evison M, Blyth KG, Bhatnagar R, Corcoran J, Saba T, Duncan T, Hallifax R, Ahmed L, West A, Pepperell JCT, Roberts M, Sivasothy P, Psallidas I, Clive AO, Latham J, Stanton AE, Maskell N, Rahman N.

BMJ Open Respir Res. 2018 Aug 3;5(1):e000307. doi: 10.1136/bmjresp-2018-000307. eCollection 2018.

18.

Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori.

Johnson SA, Ormsby MJ, McIntosh A, Tait SWG, Blyth K, Wall DM.

Cancer Gene Ther. 2019 Jul;26(7-8):183-194. doi: 10.1038/s41417-018-0039-9. Epub 2018 Aug 13. Erratum in: Cancer Gene Ther. 2018 Sep 19;:. Cancer Gene Ther. 2019 Feb 20;:.

19.

An Inconvenient Truth Concerning Surgery for Mesothelioma.

de Fonseka D, Slade M, Blyth KG, Edwards J, Evison M, Roberts M, Rahman N, Woolhouse I, Maskell NA.

J Clin Oncol. 2018 Sep 10;36(26):2745-2746. doi: 10.1200/JCO.2018.78.6590. Epub 2018 Jun 14. No abstract available.

PMID:
29902107
20.

Pre-EDIT: protocol for a randomised feasibility trial of elastance-directed intrapleural catheter or talc pleurodesis (EDIT) in malignant pleural effusion.

Martin GA, Tsim S, Kidd AC, Foster JE, McLoone P, Chalmers A, Blyth KG.

BMJ Open Respir Res. 2018 May 29;5(1):e000293. doi: 10.1136/bmjresp-2018-000293. eCollection 2018.

21.

Author Correction: CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity.

Walton JB, Farquharson M, Mason S, Port J, Kruspig B, Dowson S, Stevenson D, Murphy D, Matzuk M, Kim J, Coffelt S, Blyth K, McNeish IA.

Sci Rep. 2018 Apr 13;8(1):6231. doi: 10.1038/s41598-018-24099-3.

22.

Increased formate overflow is a hallmark of oxidative cancer.

Meiser J, Schuster A, Pietzke M, Vande Voorde J, Athineos D, Oizel K, Burgos-Barragan G, Wit N, Dhayade S, Morton JP, Dornier E, Sumpton D, Mackay GM, Blyth K, Patel KJ, Niclou SP, Vazquez A.

Nat Commun. 2018 Apr 10;9(1):1368. doi: 10.1038/s41467-018-03777-w.

23.

Early Contrast Enhancement: A novel magnetic resonance imaging biomarker of pleural malignancy.

Tsim S, Humphreys CA, Cowell GW, Stobo DB, Noble C, Woodward R, Kelly CA, Alexander L, Foster JE, Dick C, Blyth KG.

Lung Cancer. 2018 Apr;118:48-56. doi: 10.1016/j.lungcan.2018.01.014. Epub 2018 Feb 3.

24.

Survival prediction in mesothelioma using a scalable Lasso regression model: instructions for use and initial performance using clinical predictors.

Kidd AC, McGettrick M, Tsim S, Halligan DL, Bylesjo M, Blyth KG.

BMJ Open Respir Res. 2018 Jan 30;5(1):e000240. doi: 10.1136/bmjresp-2017-000240. eCollection 2018.

25.

Progress and challenges in Mesothelioma: From bench to bedside.

Blyth KG, Murphy DJ.

Respir Med. 2018 Jan;134:31-41. doi: 10.1016/j.rmed.2017.11.015. Epub 2017 Nov 26. Review.

PMID:
29413505
26.

A retrospective cohort study in severe asthma describing commonly measured biomarkers: Eosinophil count and IgE levels.

Haughney J, Morice A, Blyth KG, Lee AJ, Coutts A, McKnight E, Pavord I.

Respir Med. 2018 Jan;134:117-123. doi: 10.1016/j.rmed.2017.12.001. Epub 2017 Dec 5.

PMID:
29413497
27.

MCL-1 is a prognostic indicator and drug target in breast cancer.

Campbell KJ, Dhayade S, Ferrari N, Sims AH, Johnson E, Mason SM, Dickson A, Ryan KM, Kalna G, Edwards J, Tait SWG, Blyth K.

Cell Death Dis. 2018 Jan 16;9(2):19. doi: 10.1038/s41419-017-0035-2.

28.

Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells.

Dornier E, Rabas N, Mitchell L, Novo D, Dhayade S, Marco S, Mackay G, Sumpton D, Pallares M, Nixon C, Blyth K, Macpherson IR, Rainero E, Norman JC.

Nat Commun. 2017 Dec 21;8(1):2255. doi: 10.1038/s41467-017-02101-2.

29.

RIPK3 promotes adenovirus type 5 activity.

Weigert M, Binks A, Dowson S, Leung EYL, Athineos D, Yu X, Mullin M, Walton JB, Orange C, Ennis D, Blyth K, Tait SWG, McNeish IA.

Cell Death Dis. 2017 Dec 13;8(12):3206. doi: 10.1038/s41419-017-0110-8.

30.

CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity.

Walton JB, Farquharson M, Mason S, Port J, Kruspig B, Dowson S, Stevenson D, Murphy D, Matzuk M, Kim J, Coffelt S, Blyth K, McNeish IA.

Sci Rep. 2017 Dec 4;7(1):16827. doi: 10.1038/s41598-017-17119-1. Erratum in: Sci Rep. 2018 Apr 13;8(1):6231.

31.

Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity.

Loveridge CJ, van 't Hof RJ, Charlesworth G, King A, Tan EH, Rose L, Daroszewska A, Prior A, Ahmad I, Welsh M, Mui EJ, Ford C, Salji M, Sansom O, Blyth K, Leung HY.

Sci Rep. 2017 Oct 16;7(1):13241. doi: 10.1038/s41598-017-13346-8.

32.

Runx1 Deficiency Protects Against Adverse Cardiac Remodeling After Myocardial Infarction.

McCarroll CS, He W, Foote K, Bradley A, Mcglynn K, Vidler F, Nixon C, Nather K, Fattah C, Riddell A, Bowman P, Elliott EB, Bell M, Hawksby C, MacKenzie SM, Morrison LJ, Terry A, Blyth K, Smith GL, McBride MW, Kubin T, Braun T, Nicklin SA, Cameron ER, Loughrey CM.

Circulation. 2018 Jan 2;137(1):57-70. doi: 10.1161/CIRCULATIONAHA.117.028911. Epub 2017 Oct 13.

33.

Estimating past inhalation exposure to asbestos: A tool for risk attribution and disease screening.

Cherrie JW, McElvenny D, Blyth KG.

Int J Hyg Environ Health. 2018 Jan;221(1):27-32. doi: 10.1016/j.ijheh.2017.09.013. Epub 2017 Oct 7.

PMID:
29030093
34.

Empyema necessitans and a persistent air leak associated with rupture of an anaerobic lung abscess due to bacteroides.

Sharma V, Blyth KG.

Thorax. 2018 Jan;73(1):91-93. doi: 10.1136/thoraxjnl-2017-210462. Epub 2017 Aug 28. No abstract available. Erratum in: Thorax. 2018 Apr;73(4):404.

PMID:
28847872
35.

Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency.

Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, Roca A, Lopez J, Ichim G, Proïcs E, Rubio-Patiño C, Fort L, Yatim N, Woodham E, Orozco S, Taraborrelli L, Peltzer N, Lecis D, Machesky L, Walczak H, Albert ML, Milling S, Oberst A, Ricci JE, Ryan KM, Blyth K, Tait SWG.

Nat Cell Biol. 2017 Sep;19(9):1116-1129. doi: 10.1038/ncb3596. Epub 2017 Aug 28.

36.

Corrigendum: Modulating the therapeutic response of tumours to dietary serine and glycine starvation.

Maddocks ODK, Athineos D, Cheung EC, Lee P, Zhang T, van den Broek NJF, Mackay GM, Labuschagne CF, Gay D, Kruiswijk F, Blagih J, Vincent DF, Campbell KJ, Ceteci F, Sansom OJ, Blyth K, Vousden KH.

Nature. 2017 Aug 2;548(7665):122. doi: 10.1038/nature23471.

PMID:
28770843
37.

Introducing SEARCHBreast: a virtual resource to facilitate sharing of surplus animal material developed for breast cancer research.

Morrissey B, Holen I, Chelala C, Carter P, Jones L, Blyth K, Speirs V.

NPJ Breast Cancer. 2016 Jun 29;2:16020. doi: 10.1038/npjbcancer.2016.20. eCollection 2016.

38.

Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium.

Reid SE, Kay EJ, Neilson LJ, Henze AT, Serneels J, McGhee EJ, Dhayade S, Nixon C, Mackey JB, Santi A, Swaminathan K, Athineos D, Papalazarou V, Patella F, Román-Fernández Á, ElMaghloob Y, Hernandez-Fernaud JR, Adams RH, Ismail S, Bryant DM, Salmeron-Sanchez M, Machesky LM, Carlin LM, Blyth K, Mazzone M, Zanivan S.

EMBO J. 2017 Aug 15;36(16):2373-2389. doi: 10.15252/embj.201694912. Epub 2017 Jul 10.

39.

Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function.

van Tuyn J, Jaber-Hijazi F, MacKenzie D, Cole JJ, Mann E, Pawlikowski JS, Rai TS, Nelson DM, McBryan T, Ivanov A, Blyth K, Wu H, Milling S, Adams PD.

J Invest Dermatol. 2017 Oct;137(10):2197-2207. doi: 10.1016/j.jid.2017.05.030. Epub 2017 Jun 22.

40.

Predicting lung cancer recurrence from circulating tumour DNA. Commentary on 'Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution'.

Murphy DJ, Blyth KG.

Cell Death Differ. 2017 Sep;24(9):1473-1474. doi: 10.1038/cdd.2017.97. Epub 2017 Jun 16. No abstract available.

41.

Dobutamine stress MRI in pulmonary hypertension: relationships between stress pulmonary artery relative area change, RV performance, and 10-year survival.

Blyth KG, Bellofiore A, Jayasekera G, Foster JE, Steedman T, Chesler NC, Peacock AJ.

Pulm Circ. 2017 Apr-Jun;7(2):465-475. doi: 10.1177/2045893217704838. Epub 2017 Mar 27.

42.

Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten-Deficient Mouse Model of Prostate Carcinogenesis.

Loveridge CJ, Mui EJ, Patel R, Tan EH, Ahmad I, Welsh M, Galbraith J, Hedley A, Nixon C, Blyth K, Sansom O, Leung HY.

Cancer Res. 2017 Jun 15;77(12):3158-3168. doi: 10.1158/0008-5472.CAN-16-2565. Epub 2017 May 17.

43.

Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo.

Hock AK, Cheung EC, Humpton TJ, Monteverde T, Paulus-Hock V, Lee P, McGhee E, Scopelliti A, Murphy DJ, Strathdee D, Blyth K, Vousden KH.

Sci Rep. 2017 May 12;7(1):1837. doi: 10.1038/s41598-017-01741-0.

44.

Modulating the therapeutic response of tumours to dietary serine and glycine starvation.

Maddocks ODK, Athineos D, Cheung EC, Lee P, Zhang T, van den Broek NJF, Mackay GM, Labuschagne CF, Gay D, Kruiswijk F, Blagih J, Vincent DF, Campbell KJ, Ceteci F, Sansom OJ, Blyth K, Vousden KH.

Nature. 2017 Apr 19;544(7650):372-376. doi: 10.1038/nature22056. Erratum in: Nature. 2017 Aug 2;548(7665):122.

PMID:
28425994
45.

In vivo models in breast cancer research: progress, challenges and future directions.

Holen I, Speirs V, Morrissey B, Blyth K.

Dis Model Mech. 2017 Apr 1;10(4):359-371. doi: 10.1242/dmm.028274. Review.

46.

Dose De-escalation of Intrapleural Tissue Plasminogen Activator Therapy for Pleural Infection. The Alteplase Dose Assessment for Pleural Infection Therapy Project.

Popowicz N, Bintcliffe O, De Fonseka D, Blyth KG, Smith NA, Piccolo F, Martin G, Wong D, Edey A, Maskell N, Lee YCG.

Ann Am Thorac Soc. 2017 Jun;14(6):929-936. doi: 10.1513/AnnalsATS.201609-673OC.

PMID:
28324671
47.

The enigmatic role of RUNX1 in female-related cancers - current knowledge & future perspectives.

Riggio AI, Blyth K.

FEBS J. 2017 Aug;284(15):2345-2362. doi: 10.1111/febs.14059. Epub 2017 Apr 10. Review.

48.

Runx Genes in Breast Cancer and the Mammary Lineage.

Rooney N, Riggio AI, Mendoza-Villanueva D, Shore P, Cameron ER, Blyth K.

Adv Exp Med Biol. 2017;962:353-368. doi: 10.1007/978-981-10-3233-2_22. Review.

PMID:
28299668
49.

Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.

Hernandez-Fernaud JR, Ruengeler E, Casazza A, Neilson LJ, Pulleine E, Santi A, Ismail S, Lilla S, Dhayade S, MacPherson IR, McNeish I, Ennis D, Ali H, Kugeratski FG, Al Khamici H, van den Biggelaar M, van den Berghe PV, Cloix C, McDonald L, Millan D, Hoyle A, Kuchnio A, Carmeliet P, Valenzuela SM, Blyth K, Yin H, Mazzone M, Norman JC, Zanivan S.

Nat Commun. 2017 Feb 15;8:14206. doi: 10.1038/ncomms14206.

50.

Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation.

Bulusu V, Tumanov S, Michalopoulou E, van den Broek NJ, MacKay G, Nixon C, Dhayade S, Schug ZT, Vande Voorde J, Blyth K, Gottlieb E, Vazquez A, Kamphorst JJ.

Cell Rep. 2017 Jan 17;18(3):647-658. doi: 10.1016/j.celrep.2016.12.055.

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