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Items: 27


Toxicokinetics of 8:2 fluorotelomer alcohol (8:2-FTOH) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration.

Huang MC, Robinson VG, Waidyanatha S, Dzierlenga AL, DeVito MJ, Eifrid MA, Gibbs ST, Blystone CR.

Toxicol Rep. 2019 Aug 20;6:924-932. doi: 10.1016/j.toxrep.2019.08.009. eCollection 2019.


Toxicokinetics and bioavailability of sulfolane, a ground water contaminant, following oral and intravenous administration in rodents: A dose, species, and sex comparison.

Waidyanatha S, Black SR, Fennell TR, Watson SL, Patel PR, Cooper SD, Blake J, Robinson VG, Fernando RA, Blystone CR.

Toxicol Appl Pharmacol. 2019 Sep 15;379:114690. doi: 10.1016/j.taap.2019.114690. Epub 2019 Jul 22.


Toxicokinetics of perfluorobutane sulfonate (PFBS), perfluorohexane-1-sulphonic acid (PFHxS), and perfluorooctane sulfonic acid (PFOS) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration.

Huang MC, Dzierlenga AL, Robinson VG, Waidyanatha S, DeVito MJ, Eifrid MA, Granville CA, Gibbs ST, Blystone CR.

Toxicol Rep. 2019 Jun 28;6:645-655. doi: 10.1016/j.toxrep.2019.06.016. eCollection 2019.


Disposition and metabolism of sulfolane in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans.

Waidyanatha S, Black SR, Blystone CR, Patel PR, Watson SL, Snyder RW, Fennell TR.

Xenobiotica. 2019 Jul 5:1-12. doi: 10.1080/00498254.2019.1630786. [Epub ahead of print]


NTP Research Report on Baseline Characteristics of Diversity Outbred (J:DO) Mice Relevant to Toxicology Studies: Research Report 6 [Internet].

Harrill AH, Borghoff S, Zorrilla L, Blystone C, Kissling GE, Malarkey D, Shockley K, Travlos G, DeVito MJ.

Durham (NC): National Toxicology Program; 2018 Jun.


Human and animal evidence of potential transgenerational inheritance of health effects: An evidence map and state-of-the-science evaluation.

Walker VR, Boyles AL, Pelch KE, Holmgren SD, Shapiro AJ, Blystone CR, Devito MJ, Newbold RR, Blain R, Hartman P, Thayer KA, Rooney AA.

Environ Int. 2018 Jun;115:48-69. doi: 10.1016/j.envint.2017.12.032. Epub 2018 Mar 14. Review.


Immunotoxic and hepatotoxic effects of perfluoro-n-decanoic acid (PFDA) on female Harlan Sprague-Dawley rats and B6C3F1/N mice when administered by oral gavage for 28 days.

Frawley RP, Smith M, Cesta MF, Hayes-Bouknight S, Blystone C, Kissling GE, Harris S, Germolec D.

J Immunotoxicol. 2018 Dec;15(1):41-52. doi: 10.1080/1547691X.2018.1445145.


Exposure to butyl paraben during gestation and lactation in Hsd:Sprague dawley SD rats via dosed feed.

Roberts GK, Waidyanatha S, Kissling GE, Fletcher BL, Silinski MAR, Fennell TR, Cunny HC, Robinson VG, Blystone CR.

Toxicol Rep. 2016 Sep 11;3:774-783. doi: 10.1016/j.toxrep.2016.09.004. eCollection 2016.


A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice.

Cora MC, Gwinn W, Wilson R, King D, Waidyanatha S, Kissling GE, Brar SS, Olivera D, Blystone C, Travlos G.

Toxicol Pathol. 2017 Jul;45(5):614-623. doi: 10.1177/0192623317714343. Epub 2017 Jun 15.


Structure-activity relationships for perfluoroalkane-induced in vitro interference with rat liver mitochondrial respiration.

Wallace KB, Kissling GE, Melnick RL, Blystone CR.

Toxicol Lett. 2013 Oct 9;222(3):257-64. doi: 10.1016/j.toxlet.2013.07.025. Epub 2013 Aug 14.


Evaluation of the association between persistent organic pollutants (POPs) and diabetes in epidemiological studies: a national toxicology program workshop review.

Taylor KW, Novak RF, Anderson HA, Birnbaum LS, Blystone C, Devito M, Jacobs D, Köhrle J, Lee DH, Rylander L, Rignell-Hydbom A, Tornero-Velez R, Turyk ME, Boyles AL, Thayer KA, Lind L.

Environ Health Perspect. 2013 Jul;121(7):774-83. doi: 10.1289/ehp.1205502. Epub 2013 May 7. Review.


Metabolism and disposition of [14C]n-butyl-p-hydroxybenzoate in male and female Harlan Sprague Dawley rats following oral administration and dermal application.

Mathews JM, Brown SS, Patel PR, Black SR, Banks TT, Etheridge AS, Fennell TR, Snyder RW, Blystone CR, Waidyanatha S.

Xenobiotica. 2013 Feb;43(2):169-81. doi: 10.3109/00498254.2012.702935. Epub 2012 Jul 25.


Toxicity and carcinogenicity of androstenedione in F344/N rats and B6C3F1 mice.

Blystone CR, Elmore SA, Witt KL, Malarkey DE, Foster PM.

Food Chem Toxicol. 2011 Sep;49(9):2116-24. doi: 10.1016/j.fct.2011.05.026. Epub 2011 May 30.


In utero exposure to an AR antagonist plus an inhibitor of fetal testosterone synthesis induces cumulative effects on F1 male rats.

Hotchkiss AK, Rider CV, Furr J, Howdeshell KL, Blystone CR, Wilson VS, Gray LE Jr.

Reprod Toxicol. 2010 Sep;30(2):261-70. doi: 10.1016/j.reprotox.2010.06.001. Epub 2010 Jun 15.


Determination of the di-(2-ethylhexyl) phthalate NOAEL for reproductive development in the rat: importance of the retention of extra animals to adulthood.

Blystone CR, Kissling GE, Bishop JB, Chapin RE, Wolfe GW, Foster PM.

Toxicol Sci. 2010 Aug;116(2):640-6. doi: 10.1093/toxsci/kfq147. Epub 2010 May 19.


Cumulative and antagonistic effects of a mixture of the antiandrogens vinclozolin and iprodione in the pubertal male rat.

Blystone CR, Lambright CS, Cardon MC, Furr J, Rider CV, Hartig PC, Wilson VS, Gray LE Jr.

Toxicol Sci. 2009 Sep;111(1):179-88. doi: 10.1093/toxsci/kfp137. Epub 2009 Jun 29.


High throughput adjustable 96-well plate assay for androgen receptor binding: a practical approach for EDC screening using the chimpanzee AR.

Hartig PC, Cardon MC, Blystone CR, Gray LE Jr, Wilson VS.

Toxicol Lett. 2008 Sep 26;181(2):126-31. doi: 10.1016/j.toxlet.2008.07.008. Epub 2008 Jul 18.


A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner.

Howdeshell KL, Wilson VS, Furr J, Lambright CR, Rider CV, Blystone CR, Hotchkiss AK, Gray LE Jr.

Toxicol Sci. 2008 Sep;105(1):153-65. doi: 10.1093/toxsci/kfn077. Epub 2008 Apr 14.


Diverse mechanisms of anti-androgen action: impact on male rat reproductive tract development.

Wilson VS, Blystone CR, Hotchkiss AK, Rider CV, Gray LE Jr.

Int J Androl. 2008 Apr;31(2):178-87. doi: 10.1111/j.1365-2605.2007.00861.x. Review.


Fifteen years after "Wingspread"--environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go.

Hotchkiss AK, Rider CV, Blystone CR, Wilson VS, Hartig PC, Ankley GT, Foster PM, Gray CL, Gray LE.

Toxicol Sci. 2008 Oct;105(2):235-59. doi: 10.1093/toxsci/kfn030. Epub 2008 Feb 16. Review.


Iprodione delays male rat pubertal development, reduces serum testosterone levels, and decreases ex vivo testicular testosterone production.

Blystone CR, Lambright CS, Furr J, Wilson VS, Gray LE Jr.

Toxicol Lett. 2007 Nov 1;174(1-3):74-81. Epub 2007 Aug 31.


Sensitivity of fetal rat testicular steroidogenesis to maternal prochloraz exposure and the underlying mechanism of inhibition.

Blystone CR, Lambright CS, Howdeshell KL, Furr J, Sternberg RM, Butterworth BC, Durhan EJ, Makynen EA, Ankley GT, Wilson VS, Leblanc GA, Gray LE Jr.

Toxicol Sci. 2007 Jun;97(2):512-9. Epub 2007 Mar 15.


Prochloraz inhibits testosterone production at dosages below those that affect androgen-dependent organ weights or the onset of puberty in the male Sprague Dawley rat.

Blystone CR, Furr J, Lambright CS, Howdeshell KL, Ryan BC, Wilson VS, Leblanc GA, Gray LE Jr.

Toxicol Sci. 2007 May;97(1):65-74. Epub 2007 Jan 18.


Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat.

Goetz AK, Ren H, Schmid JE, Blystone CR, Thillainadarajah I, Best DS, Nichols HP, Strader LF, Wolf DC, Narotsky MG, Rockett JC, Dix DJ.

Toxicol Sci. 2007 Jan;95(1):227-39. Epub 2006 Oct 3.


Effect of conazole fungicides on reproductive development in the female rat.

Rockett JC, Narotsky MG, Thompson KE, Thillainadarajah I, Blystone CR, Goetz AK, Ren H, Best DS, Murrell RN, Nichols HP, Schmid JE, Wolf DC, Dix DJ.

Reprod Toxicol. 2006 Nov;22(4):647-58. Epub 2006 Jun 12.


Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides.

Tully DB, Bao W, Goetz AK, Blystone CR, Ren H, Schmid JE, Strader LF, Wood CR, Best DS, Narotsky MG, Wolf DC, Rockett JC, Dix DJ.

Toxicol Appl Pharmacol. 2006 Sep 15;215(3):260-73. Epub 2006 Apr 27.


Activation of EphB2 and its ligands promotes vascular smooth muscle cell proliferation.

Woods TC, Blystone CR, Yoo J, Edelman ER.

J Biol Chem. 2002 Jan 18;277(3):1924-7. Epub 2001 Nov 12.

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