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Items: 37


The Next MacGyver: A Platform to Study Intestinal Organoids Using High-Throughput Computer-Driven Microinjection.

Blutt SE.

Cell Mol Gastroenterol Hepatol. 2018 Jul 23;6(3):352-353. doi: 10.1016/j.jcmgh.2018.06.010. eCollection 2018. No abstract available.


Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases.

Blutt SE, Crawford SE, Ramani S, Zou WY, Estes MK.

Cell Mol Gastroenterol Hepatol. 2017 Dec 9;5(3):241-251. doi: 10.1016/j.jcmgh.2017.12.001. eCollection 2018 Mar. Review.


Human organoid cultures: transformative new tools for human virus studies.

Ramani S, Crawford SE, Blutt SE, Estes MK.

Curr Opin Virol. 2018 Apr;29:79-86. doi: 10.1016/j.coviro.2018.04.001. Epub 2018 Apr 12. Review.


Novel Segment- and Host-Specific Patterns of Enteroaggregative Escherichia coli Adherence to Human Intestinal Enteroids.

Rajan A, Vela L, Zeng XL, Yu X, Shroyer N, Blutt SE, Poole NM, Carlin LG, Nataro JP, Estes MK, Okhuysen PC, Maresso AW.

MBio. 2018 Feb 20;9(1). pii: e02419-17. doi: 10.1128/mBio.02419-17.


Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation.

Zou WY, Blutt SE, Zeng XL, Chen MS, Lo YH, Castillo-Azofeifa D, Klein OD, Shroyer NF, Donowitz M, Estes MK.

Cell Rep. 2018 Jan 23;22(4):1003-1015. doi: 10.1016/j.celrep.2017.12.093. Epub 2018 Jan 28.


Gastrointestinal microphysiological systems.

Blutt SE, Broughman JR, Zou W, Zeng XL, Karandikar UC, In J, Zachos NC, Kovbasnjuk O, Donowitz M, Estes MK.

Exp Biol Med (Maywood). 2017 Oct;242(16):1633-1642. doi: 10.1177/1535370217710638. Epub 2017 May 23. Review.


Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections.

Zou WY, Blutt SE, Crawford SE, Ettayebi K, Zeng XL, Saxena K, Ramani S, Karandikar UC, Zachos NC, Estes MK.

Methods Mol Biol. 2017 Mar 31. doi: 10.1007/7651_2017_1. [Epub ahead of print]


A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection.

Saxena K, Simon LM, Zeng XL, Blutt SE, Crawford SE, Sastri NP, Karandikar UC, Ajami NJ, Zachos NC, Kovbasnjuk O, Donowitz M, Conner ME, Shaw CA, Estes MK.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E570-E579. doi: 10.1073/pnas.1615422114. Epub 2017 Jan 9.


Replication of human noroviruses in stem cell-derived human enteroids.

Ettayebi K, Crawford SE, Murakami K, Broughman JR, Karandikar U, Tenge VR, Neill FH, Blutt SE, Zeng XL, Qu L, Kou B, Opekun AR, Burrin D, Graham DY, Ramani S, Atmar RL, Estes MK.

Science. 2016 Sep 23;353(6306):1387-1393. Epub 2016 Aug 25.


Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology.

Zachos NC, Kovbasnjuk O, Foulke-Abel J, In J, Blutt SE, de Jonge HR, Estes MK, Donowitz M.

J Biol Chem. 2016 Feb 19;291(8):3759-66. doi: 10.1074/jbc.R114.635995. Epub 2015 Dec 16. Review.


Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology.

Saxena K, Blutt SE, Ettayebi K, Zeng XL, Broughman JR, Crawford SE, Karandikar UC, Sastri NP, Conner ME, Opekun AR, Graham DY, Qureshi W, Sherman V, Foulke-Abel J, In J, Kovbasnjuk O, Zachos NC, Donowitz M, Estes MK.

J Virol. 2015 Oct 7;90(1):43-56. doi: 10.1128/JVI.01930-15. Print 2016 Jan 1.


Human enteroids as an ex-vivo model of host-pathogen interactions in the gastrointestinal tract.

Foulke-Abel J, In J, Kovbasnjuk O, Zachos NC, Ettayebi K, Blutt SE, Hyser JM, Zeng XL, Crawford SE, Broughman JR, Estes MK, Donowitz M.

Exp Biol Med (Maywood). 2014 Sep;239(9):1124-34. doi: 10.1177/1535370214529398. Epub 2014 Apr 9. Review.


The gastrointestinal frontier: IgA and viruses.

Blutt SE, Conner ME.

Front Immunol. 2013 Nov 28;4:402. doi: 10.3389/fimmu.2013.00402. Review.


FoxP3+ regulatory T cells are not important for rotavirus clearance or the early antibody response to rotavirus.

Miller AD, Blutt SE, Conner ME.

Microbes Infect. 2014 Jan;16(1):67-72. doi: 10.1016/j.micinf.2013.09.004. Epub 2013 Oct 2.


Lymphotoxin alpha-deficient mice clear persistent rotavirus infection after local generation of mucosal IgA.

Lopatin U, Blutt SE, Conner ME, Kelsall BL.

J Virol. 2013 Jan;87(1):524-30. doi: 10.1128/JVI.01801-12. Epub 2012 Oct 24.


IgA is important for clearance and critical for protection from rotavirus infection.

Blutt SE, Miller AD, Salmon SL, Metzger DW, Conner ME.

Mucosal Immunol. 2012 Nov;5(6):712-9. doi: 10.1038/mi.2012.51. Epub 2012 Jun 27.


Host response to probiotics determined by nutritional status of rotavirus-infected neonatal mice.

Preidis GA, Saulnier DM, Blutt SE, Mistretta TA, Riehle KP, Major AM, Venable SF, Barrish JP, Finegold MJ, Petrosino JF, Guerrant RL, Conner ME, Versalovic J.

J Pediatr Gastroenterol Nutr. 2012 Sep;55(3):299-307.


Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine.

Preidis GA, Saulnier DM, Blutt SE, Mistretta TA, Riehle KP, Major AM, Venable SF, Finegold MJ, Petrosino JF, Conner ME, Versalovic J.

FASEB J. 2012 May;26(5):1960-9. doi: 10.1096/fj.10-177980. Epub 2012 Jan 20.


Immune mediators of rotavirus antigenemia clearance in mice.

Marcelin G, Miller AD, Blutt SE, Conner ME.

J Virol. 2011 Aug;85(15):7937-41. doi: 10.1128/JVI.00844-10. Epub 2011 May 18.


Differential requirements for T cells in viruslike particle- and rotavirus-induced protective immunity.

Blutt SE, Warfield KL, Estes MK, Conner ME.

J Virol. 2008 Mar;82(6):3135-8. doi: 10.1128/JVI.01727-07. Epub 2008 Jan 9.


Rotavirus antigenemia in children is associated with viremia.

Blutt SE, Matson DO, Crawford SE, Staat MA, Azimi P, Bennett BL, Piedra PA, Conner ME.

PLoS Med. 2007 Apr;4(4):e121.


Expression of rotavirus NSP4 alters the actin network organization through the actin remodeling protein cofilin.

Berkova Z, Crawford SE, Blutt SE, Morris AP, Estes MK.

J Virol. 2007 Apr;81(7):3545-53. Epub 2007 Jan 17.


Rotavirus: to the gut and beyond!

Blutt SE, Conner ME.

Curr Opin Gastroenterol. 2007 Jan;23(1):39-43. Review.


Rotavirus infection enhances lipopolysaccharide-induced intussusception in a mouse model.

Warfield KL, Blutt SE, Crawford SE, Kang G, Conner ME.

J Virol. 2006 Dec;80(24):12377-86. Epub 2006 Sep 27.


Active viremia in rotavirus-infected mice.

Blutt SE, Fenaux M, Warfield KL, Greenberg HB, Conner ME.

J Virol. 2006 Jul;80(13):6702-5.


Host, viral, and vaccine factors that determine protective efficacy induced by rotavirus and virus-like particles (VLPs).

Blutt SE, Warfield KL, O'Neal CM, Estes MK, Conner ME.

Vaccine. 2006 Feb 20;24(8):1170-9. Epub 2005 Sep 9.


The VP7 outer capsid protein of rotavirus induces polyclonal B-cell activation.

Blutt SE, Crawford SE, Warfield KL, Lewis DE, Estes MK, Conner ME.

J Virol. 2004 Jul;78(13):6974-81.


Kinetics of rotavirus infection in mice are not altered in a ground-based model of spaceflight.

Blutt SE, Conner ME.

Aviat Space Environ Med. 2004 Mar;75(3):215-9.


Rotavirus antigenaemia and viraemia: a common event?

Blutt SE, Kirkwood CD, ParreƱo V, Warfield KL, Ciarlet M, Estes MK, Bok K, Bishop RF, Conner ME.

Lancet. 2003 Nov 1;362(9394):1445-9.


Early response to rotavirus infection involves massive B cell activation.

Blutt SE, Warfield KL, Lewis DE, Conner ME.

J Immunol. 2002 Jun 1;168(11):5716-21.


VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment.

Ciarlet M, Crawford SE, Cheng E, Blutt SE, Rice DA, Bergelson JM, Estes MK.

J Virol. 2002 Feb;76(3):1109-23.


Novel nonsecosteroidal vitamin D receptor modulator inhibits the growth of LNCaP xenograft tumors in athymic mice without increased serum calcium.

Polek TC, Murthy S, Blutt SE, Boehm MF, Zou A, Weigel NL, Allegretto EA.

Prostate. 2001 Nov 1;49(3):224-33.


A calcitriol analogue, EB1089, inhibits the growth of LNCaP tumors in nude mice.

Blutt SE, Polek TC, Stewart LV, Kattan MW, Weigel NL.

Cancer Res. 2000 Feb 15;60(4):779-82.


Calcitriol-induced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2.

Blutt SE, McDonnell TJ, Polek TC, Weigel NL.

Endocrinology. 2000 Jan;141(1):10-7.


Vitamin D and prostate cancer.

Blutt SE, Weigel NL.

Proc Soc Exp Biol Med. 1999 Jun;221(2):89-98. Review.


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