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Items: 1 to 50 of 219

1.

Effects of Rifamycin Coadministration on Bedaquiline Desmethylation in Healthy Adult Volunteers.

Healan AM, Salata RA, Griffiss JM, Proskin HM, O'Riordan MA, Gray WA, Blumer JL.

Clin Pharmacol Drug Dev. 2019 May;8(4):436-442. doi: 10.1002/cpdd.639. Epub 2018 Nov 30.

PMID:
30500116
2.

Mycobactericidal activity of bedaquiline plus rifabutin or rifampin in ex vivo whole blood cultures of healthy volunteers: A randomized controlled trial.

Wallis RS, Good CE, O'Riordan MA, Blumer JL, Jacobs MR, Griffiss JM, Healan A, Salata RA.

PLoS One. 2018 May 2;13(5):e0196756. doi: 10.1371/journal.pone.0196756. eCollection 2018.

3.

A Phase 1 Pharmacokinetic and Safety Study of Extended-Duration, High-dose Cefixime for Cephalosporin-resistant Neisseria gonorrhoeae in the Pharynx.

Barbee LA, Nayak SU, Blumer JL, OʼRiordan MA, Gray W, Zenilman JM, Golden MR, Griffiss JM.

Sex Transm Dis. 2018 Oct;45(10):677-683. doi: 10.1097/OLQ.0000000000000844.

PMID:
29624558
4.

Impact of Rifabutin or Rifampin on Bedaquiline Safety, Tolerability, and Pharmacokinetics Assessed in a Randomized Clinical Trial with Healthy Adult Volunteers.

Healan AM, Griffiss JM, Proskin HM, O'Riordan MA, Gray WA, Salata RA, Blumer JL.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e00855-17. doi: 10.1128/AAC.00855-17. Print 2018 Jan.

5.

Intravenous Zanamivir in Hospitalized Patients With Influenza.

Bradley JS, Blumer JL, Romero JR, Michaels MG, Munoz FM, Kimberlin DW, Pahud B, DeBiasi RL, Yamamoto G, Roberts G, Hossain M, Shortino D, Yates PJ, Adams B, Peppercorn A.

Pediatrics. 2017 Nov;140(5). pii: e20162727. doi: 10.1542/peds.2016-2727.

6.

A Multicenter, Randomized, Observer-blinded, Active-controlled Study Evaluating the Safety and Effectiveness of Ceftaroline Compared With Ceftriaxone Plus Vancomycin in Pediatric Patients With Complicated Community-acquired Bacterial Pneumonia.

Blumer JL, Ghonghadze T, Cannavino C, O'Neal T, Jandourek A, Friedland HD, Bradley JS.

Pediatr Infect Dis J. 2016 Jul;35(7):760-6. doi: 10.1097/INF.0000000000001160.

PMID:
27078119
7.

Accuracy of the Spacelabs 90217 ambulatory blood pressure monitor in a pediatric population.

Redwine KM, James LP, O'Riordan M, Sullivan JE, Blumer JL; Network of Pediatric Pharmacology Research Units.

Blood Press Monit. 2015 Oct;20(5):295-8. doi: 10.1097/MBP.0000000000000132.

8.
9.

Pharmacokinetics, Safety and Tolerability of Single Dose Dalbavancin in Children 12-17 Years of Age.

Bradley JS, Puttagunta S, Rubino CM, Blumer JL, Dunne M, Sullivan JE.

Pediatr Infect Dis J. 2015 Jul;34(7):748-52. doi: 10.1097/INF.0000000000000646.

PMID:
25551831
10.

Eszopiclone for insomnia associated with attention-deficit/hyperactivity disorder.

Sangal RB, Blumer JL, Lankford DA, Grinnell TA, Huang H.

Pediatrics. 2014 Oct;134(4):e1095-103. doi: 10.1542/peds.2013-4221.

11.

A population pharmacokinetic modeling approach shows that serum penicillin G concentrations are below inhibitory concentrations by two weeks after benzathine penicillin G injection in the majority of young adults.

Neely M, Kaplan EL, Blumer JL, Faix DJ, Broderick MP.

Antimicrob Agents Chemother. 2014 Nov;58(11):6735-41. doi: 10.1128/AAC.02744-14. Epub 2014 Sep 2.

12.

Serum penicillin G levels are lower than expected in adults within two weeks of administration of 1.2 million units.

Broderick MP, Hansen CJ, Russell KL, Kaplan EL, Blumer JL, Faix DJ.

PLoS One. 2011;6(10):e25308. doi: 10.1371/journal.pone.0025308. Epub 2011 Oct 4.

13.

Assessing time to pulmonary function benefit following antibiotic treatment of acute cystic fibrosis exacerbations.

VanDevanter DR, O'Riordan MA, Blumer JL, Konstan MW.

Respir Res. 2010 Oct 6;11:137. doi: 10.1186/1465-9921-11-137.

14.

Pharmacokinetics and tolerability of single-dose intravenous ertapenem in infants, children, and adolescents.

Abdel-Rahman SM, Kearns GL, Topelberg S, Jacobs RF, Mistry GC, Majumdar A, Xu Y, Wagner JA, Kitchen CJ, Groff M, Herman G, Blumer JL.

Pediatr Infect Dis J. 2010 Dec;29(12):1072-6. doi: 10.1097/INF.0b013e3181e82608.

15.

Tinea capitis: predictive value of symptoms and time to cure with griseofulvin treatment.

Lorch Dauk KC, Comrov E, Blumer JL, O'Riordan MA, Furman LM.

Clin Pediatr (Phila). 2010 Mar;49(3):280-6. doi: 10.1177/0009922809338313. Epub 2009 Jun 1.

PMID:
19487765
16.

Controlled clinical trial of zolpidem for the treatment of insomnia associated with attention-deficit/ hyperactivity disorder in children 6 to 17 years of age.

Blumer JL, Findling RL, Shih WJ, Soubrane C, Reed MD.

Pediatrics. 2009 May;123(5):e770-6. doi: 10.1542/peds.2008-2945.

PMID:
19403468
17.

Pharmacokinetics of azithromycin in plasma and sinus mucosal tissue following administration of extended-release or immediate-release formulations in adult patients with chronic rhinosinusitis.

Fang AF, Palmer JN, Chiu AG, Blumer JL, Crownover PH, Campbell MD, Damle BD.

Int J Antimicrob Agents. 2009 Jul;34(1):67-71. doi: 10.1016/j.ijantimicag.2009.01.014.

PMID:
19307106
18.

Acetaminophen-associated hepatic injury: evaluation of acetaminophen protein adducts in children and adolescents with acetaminophen overdose.

James LP, Capparelli EV, Simpson PM, Letzig L, Roberts D, Hinson JA, Kearns GL, Blumer JL, Sullivan JE; Network of Pediatric Pharmacology Research Units, National Institutes of Child Health and Human Development.

Clin Pharmacol Ther. 2008 Dec;84(6):684-90. doi: 10.1038/clpt.2008.190. Epub 2008 Oct 15.

19.

A randomized comparative study of levofloxacin versus amoxicillin/clavulanate for treatment of infants and young children with recurrent or persistent acute otitis media.

Noel GJ, Blumer JL, Pichichero ME, Hedrick JA, Schwartz RH, Balis DA, Melkote R, Bagchi P, Arguedas A.

Pediatr Infect Dis J. 2008 Jun;27(6):483-9. doi: 10.1097/INF.0b013e318168d2cb.

PMID:
18449063
20.

Potential pharmacokinetic basis for zolpidem dosing in children with sleep difficulties.

Blumer JL, Reed MD, Steinberg F, O'Riordan MA, Rosen CL, Springer MA, Christensen M, Glaze D; NICHD PPRU Network.

Clin Pharmacol Ther. 2008 Apr;83(4):551-8. Epub 2007 Oct 24.

PMID:
17957186
21.

Comparative safety profile of levofloxacin in 2523 children with a focus on four specific musculoskeletal disorders.

Noel GJ, Bradley JS, Kauffman RE, Duffy CM, Gerbino PG, Arguedas A, Bagchi P, Balis DA, Blumer JL.

Pediatr Infect Dis J. 2007 Oct;26(10):879-91.

PMID:
17901792
22.

Comparative study of levofloxacin in the treatment of children with community-acquired pneumonia.

Bradley JS, Arguedas A, Blumer JL, Sáez-Llorens X, Melkote R, Noel GJ.

Pediatr Infect Dis J. 2007 Oct;26(10):868-78.

PMID:
17901791
23.

Single-dose pharmacokinetics of intravenous itraconazole and hydroxypropyl-beta-cyclodextrin in infants, children, and adolescents.

Abdel-Rahman SM, Jacobs RF, Massarella J, Kauffman RE, Bradley JS, Kimko HC, Kearns GL, Shalayda K, Curtin C, Maldonado SD, Blumer JL.

Antimicrob Agents Chemother. 2007 Aug;51(8):2668-73. Epub 2007 May 21.

24.

Population pharmacokinetic model for gatifloxacin in pediatric patients.

Rubino CM, Capparelli EV, Bradley JS, Blumer JL, Kearns GL, Reed M, Jacobs RF, Cirincione B, Grasela DM.

Antimicrob Agents Chemother. 2007 Apr;51(4):1246-52. Epub 2007 Jan 12.

25.

A multicenter study of the pharmacokinetics of lisinopril in pediatric patients with hypertension.

Hogg RJ, Delucchi A, Sakihara G, Wells TG, Tenney F, Batisky DL, Blumer JL, Vogt BA, Lo MW, Hand E, Panebianco D, Rippley R, Shaw W, Shahinfar S.

Pediatr Nephrol. 2007 May;22(5):695-701. Epub 2007 Jan 10.

PMID:
17216247
26.

Comparative effects of single-dose ceftriaxone versus three oral antibiotic regimens on stool colonization by resistant bacilli in children.

Toltzis P, Dul M, O'Riordan MA, Toltzis H, Blumer JL.

Pediatr Infect Dis J. 2007 Jan;26(1):25-30.

PMID:
17195701
27.

The pharmacokinetics and safety of micafungin, a novel echinocandin, in premature infants.

Heresi GP, Gerstmann DR, Reed MD, van den Anker JN, Blumer JL, Kovanda L, Keirns JJ, Buell DN, Kearns GL.

Pediatr Infect Dis J. 2006 Dec;25(12):1110-5.

PMID:
17133155
28.

Evolution of a new drug formulation: the rationale for high-dose, short-course therapy with azithromycin.

Blumer JL.

Int J Antimicrob Agents. 2005 Dec;26 Suppl 3:S143-7. Review.

PMID:
16543075
31.

Cytokines and toxicity in acetaminophen overdose.

James LP, Simpson PM, Farrar HC, Kearns GL, Wasserman GS, Blumer JL, Reed MD, Sullivan JE, Hinson JA.

J Clin Pharmacol. 2005 Oct;45(10):1165-71.

PMID:
16172181
32.

Fluticasone propionate plasma concentration and systemic effect: effect of delivery device and duration of administration.

Whelan GJ, Blumer JL, Martin RJ, Szefler SJ; Asthma Clinical Research Network and the Pediatric Pharmacology Research Unit Network.

J Allergy Clin Immunol. 2005 Sep;116(3):525-30.

PMID:
16159619
33.

Pharmacokinetics of famotidine in infants.

Wenning LA, Murphy MG, James LP, Blumer JL, Marshall JD, Baier J, Scheimann AO, Panebianco DL, Zhong L, Eisenhandler R, Yeh KC, Kearns GL.

Clin Pharmacokinet. 2005;44(4):395-406.

PMID:
15828852
34.

Pharmacokinetics of gatifloxacin in infants and children.

Capparelli EV, Reed MD, Bradley JS, Kearns GL, Jacobs RF, Damle BD, Blumer JL, Grasela DM.

Antimicrob Agents Chemother. 2005 Mar;49(3):1106-12.

35.

Impact of amoxicillin on pneumococcal colonization compared with other therapies for acute otitis media.

Toltzis P, Dul M, O'Riordan MA, Toltzis H, Blumer JL.

Pediatr Infect Dis J. 2005 Jan;24(1):24-8.

PMID:
15665706
36.

Levofloxacin pharmacokinetics in children.

Chien S, Wells TG, Blumer JL, Kearns GL, Bradley JS, Bocchini JA Jr, Natarajan J, Maldonado S, Noel GJ.

J Clin Pharmacol. 2005 Feb;45(2):153-60.

PMID:
15647407
37.

Quetiapine in nine youths with autistic disorder.

Findling RL, McNamara NK, Gracious BL, O'Riordan MA, Reed MD, Demeter C, Blumer JL.

J Child Adolesc Psychopharmacol. 2004 Summer;14(2):287-94.

PMID:
15319025
38.

Rationale for single and high dose treatment regimens with azithromycin.

Gordon EM, Blumer JL.

Pediatr Infect Dis J. 2004 Feb;23(2 Suppl):S102-7. Review.

PMID:
14770072
39.

What safety data are needed for a medication to treat gastroesophageal reflux in premature infants? In children younger than 1 year of age? How to design a long-term safety registry for children?

Blumer JL, Heyman MB, Vandenplas Y, Ward RM.

J Pediatr Gastroenterol Nutr. 2003 Nov-Dec;37 Suppl 1:S69-71. Review. No abstract available.

PMID:
14685082
40.

Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis.

Dunne MW, Khurana C, Mohs AA, Rodriguez A, Arrieta A, McLinn S, Krogstad JA, Blatter M, Schwartz R, Vargas SL, Emparanza P, Fernandez P, Gooch WM 3rd, Aspin M, Podgore J, Roine I, Blumer JL, Ehrlich GD, Chow J.

Antimicrob Agents Chemother. 2003 Aug;47(8):2663-5.

41.

An open-label pilot study of St. John's wort in juvenile depression.

Findling RL, McNamara NK, O'Riordan MA, Reed MD, Demeter CA, Branicky LA, Blumer JL.

J Am Acad Child Adolesc Psychiatry. 2003 Aug;42(8):908-14.

PMID:
12874492
42.

Intravenous and oral itraconazole versus intravenous and oral fluconazole for long-term antifungal prophylaxis in allogeneic hematopoietic stem-cell transplant recipients. A multicenter, randomized trial.

Winston DJ, Maziarz RT, Chandrasekar PH, Lazarus HM, Goldman M, Blumer JL, Leitz GJ, Territo MC.

Ann Intern Med. 2003 May 6;138(9):705-13.

PMID:
12729424
43.

Cefotaxime-resistant bacteria colonizing older people admitted to an acute care hospital.

Bonomo RA, Donskey CJ, Blumer JL, Hujer AM, Hoyenm CK, Jacobs MR, Whalen CC, Salata RA.

J Am Geriatr Soc. 2003 Apr;51(4):519-22.

44.

Developing strategies for psychopharmacological studies in preschool children.

Greenhill LL, Jensen PS, Abikoff H, Blumer JL, Deveaugh-Geiss J, Fisher C, Hoagwood K, Kratochvil CJ, Lahey BB, Laughren T, Leckman J, Petti TA, Pope K, Shaffer D, Vitiello B, Zeanah C.

J Am Acad Child Adolesc Psychiatry. 2003 Apr;42(4):406-14. Review.

PMID:
12649627
45.

Pharmacokinetics of quinapril in children: assessment during substitution for chronic angiotensin-converting enzyme inhibitor treatment.

Blumer JL, Daniels SR, Dreyer WJ, Batisky D, Walson PD, Roman D, Ouellet D.

J Clin Pharmacol. 2003 Feb;43(2):128-32.

PMID:
12616664
46.

Cefepime use in a pediatric intensive care unit reduces colonization with resistant bacilli.

Toltzis P, Dul M, O'Riordan MA, Salvator A, Rosolowski B, Toltzis H, Blumer JL.

Pediatr Infect Dis J. 2003 Feb;22(2):109-14.

PMID:
12586972
47.

Pharmacokinetic and tolerability assessment of a pediatric oral formulation of pentoxifylline in kawasaki disease.

Best BM, Burns JC, DeVincenzo J, Phelps SJ, Blumer JL, Wilson JT, Capparelli EV, Connor JD; Pediatric Pharmacology Research Unit Network.

Curr Ther Res Clin Exp. 2003 Feb;64(2):96-115. doi: 10.1016/S0011-393X(03)00018-3.

48.

Famotidine disposition in children and adolescents with chronic renal insufficiency.

Maples HD, James LP, Stowe CD, Jones DP, Hak EB, Blumer JL, Vogt B, Wilson JT, Kearns GL, Wells TG; Network of Pediatric Pharmacology Research Units.

J Clin Pharmacol. 2003 Jan;43(1):7-14.

PMID:
12520622
49.

The emergence of rational therapeutics from the traditions of clinical practice.

Blumer JL.

Curr Ther Res Clin Exp. 2003;64:1-3. doi: 10.1016/j.curtheres.2003.09.007. No abstract available.

50.

Antibiotics and breast-feeding: a critical review of the literature.

Chung AM, Reed MD, Blumer JL.

Paediatr Drugs. 2002;4(12):817-37. Review.

PMID:
12431134

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