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Items: 1 to 50 of 535

1.

Detection and characterization of bacterial polysaccharides in drug-resistant enterococci.

Ali L, Blum HE, Sakιnç T.

Glycoconj J. 2019 Oct;36(5):429-438. doi: 10.1007/s10719-019-09881-3. Epub 2019 Jun 22.

PMID:
31230165
2.

The human microbiome.

Blum HE.

Adv Med Sci. 2017 Sep;62(2):414-420. doi: 10.1016/j.advms.2017.04.005. Epub 2017 Jul 13. Review.

PMID:
28711782
3.

Gallensteine, Cholestase und Leberschädigung: Hepatobiliäre Erkrankungen.

Blum HE.

Dtsch Med Wochenschr. 2016 Nov;141(23):1676. Epub 2016 Nov 17. German. No abstract available.

PMID:
27855455
4.

History and Global Burden of Viral Hepatitis.

Blum HE.

Dig Dis. 2016;34(4):293-302. doi: 10.1159/000444466. Epub 2016 May 11.

PMID:
27170381
5.

Identification and functional characterization of the putative polysaccharide biosynthesis protein (CapD) of Enterococcus faecium U0317.

Ali L, Spiess M, Wobser D, Rodriguez M, Blum HE, Sakιnç T.

Infect Genet Evol. 2016 Jan;37:215-24. doi: 10.1016/j.meegid.2015.11.020. Epub 2015 Nov 30.

PMID:
26611826
6.

The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice.

Trierweiler C, Hockenjos B, Zatloukal K, Thimme R, Blum HE, Wagner EF, Hasselblatt P.

Cell Death Differ. 2016 Apr;23(4):576-82. doi: 10.1038/cdd.2015.121. Epub 2015 Oct 16.

7.

Screening for hepatocellular carcinoma by Egyptian physicians.

Hassany SM, Moustafa EF, Taher ME, Abdeltwab AA, Blum HE.

World J Gastrointest Oncol. 2015 Sep 15;7(9):161-71. doi: 10.4251/wjgo.v7.i9.161.

8.

Hepatitis B Virus-Infected HepG2hNTCP Cells Serve as a Novel Immunological Tool To Analyze the Antiviral Efficacy of CD8+ T Cells In Vitro.

Hoh A, Heeg M, Ni Y, Schuch A, Binder B, Hennecke N, Blum HE, Nassal M, Protzer U, Hofmann M, Urban S, Thimme R.

J Virol. 2015 Jul;89(14):7433-8. doi: 10.1128/JVI.00605-15. Epub 2015 May 13.

9.

[Is scientific misconduct preventable? stem cell scandal 2014: study was faked].

Blum HE.

Dtsch Med Wochenschr. 2015 Mar;140(5):364-5. doi: 10.1055/s-0041-100613. Epub 2015 Mar 3. German. No abstract available.

PMID:
25734681
10.

Tetramer enrichment reveals the presence of phenotypically diverse hepatitis C virus-specific CD8+ T cells in chronic infection.

Nitschke K, Flecken T, Schmidt J, Gostick E, Marget M, Neumann-Haefelin C, Blum HE, Price DA, Thimme R.

J Virol. 2015 Jan;89(1):25-34. doi: 10.1128/JVI.02242-14. Epub 2014 Oct 15.

11.

Advances in individualized and regenerative medicine.

Blum HE.

Adv Med Sci. 2014 Mar;59(1):7-12. doi: 10.1016/j.advms.2013.12.001. Epub 2014 Mar 22. Review.

PMID:
24797966
12.

[What contribution makes DNA sequencing in clinical practice? - before widespread application DNA sequencing has to be optimized].

Blum HE.

Dtsch Med Wochenschr. 2014 May;139(18):932. doi: 10.1055/s-0033-1353901. Epub 2014 Apr 23. German. No abstract available.

PMID:
24760713
13.

Cell therapies and regenerative medicine.

Blum HE.

Hepatol Int. 2014 Apr;8(2):158-65. doi: 10.1007/s12072-013-9512-6. Epub 2014 Jan 19.

PMID:
26202498
14.

[Stimulus-triggered acquisition of pluripotency: a new perspective in reprogramming of differentiated somatic cells].

Blum HE.

Dtsch Med Wochenschr. 2014 Feb;139(9):441-3. doi: 10.1055/s-0034-1369847. Epub 2014 Feb 20. Review. German. No abstract available.

PMID:
24557999
15.

Current state of nonsurgical therapies for cholangiocarcinoma.

Brass V, Kuhlmann JB, Blum HE.

Hepat Oncol. 2014 Jan;1(1):135-142. doi: 10.2217/hep.13.9. Epub 2013 Dec 20. Review.

16.

Generation of stable 3'-mRNA cleavage fragments induced by siRNA in cells with high-levels of duck hepatitis B virus replication.

Lan L, Mao Q, Blum HE.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):834-9. doi: 10.1016/j.bbrc.2013.12.048. Epub 2013 Dec 14.

PMID:
24342609
17.

Immunodominance and functional alterations of tumor-associated antigen-specific CD8+ T-cell responses in hepatocellular carcinoma.

Flecken T, Schmidt N, Hild S, Gostick E, Drognitz O, Zeiser R, Schemmer P, Bruns H, Eiermann T, Price DA, Blum HE, Neumann-Haefelin C, Thimme R.

Hepatology. 2014 Apr;59(4):1415-26. doi: 10.1002/hep.26731. Epub 2014 Feb 20.

18.

[Sofosbuvir: alternative in hepatitis C infection?].

Blum HE.

Dtsch Med Wochenschr. 2013 Aug;138(33):1646-7. doi: 10.1055/s-0032-1329055. Epub 2013 Aug 2. German. No abstract available.

PMID:
23913349
19.

Reforming the EU environment for clinical trials: what are the challenges?

Fears R, Blum HE, Kelleher D, Meunier F, Souhami R.

QJM. 2013 Sep;106(9):787-9. doi: 10.1093/qjmed/hct149. Epub 2013 Jul 27. No abstract available.

PMID:
23893498
20.

Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies.

Fofana I, Zona L, Thumann C, Heydmann L, Durand SC, Lupberger J, Blum HE, Pessaux P, Gondeau C, Reynolds GM, McKeating JA, Grunert F, Thompson J, Zeisel MB, Baumert TF.

J Virol. 2013 Sep;87(18):10405-10. doi: 10.1128/JVI.01691-13. Epub 2013 Jul 17.

21.

[Pathology: pacemaker of advances in medicine].

Schirmacher P, Blum HE.

Dtsch Med Wochenschr. 2013 May;138(20):1043. doi: 10.1055/s-0033-1343166. Epub 2013 May 13. German. No abstract available.

PMID:
23670258
22.

T-cell responses in hepatitis B and C virus infection: similarities and differences.

Schmidt J, Blum HE, Thimme R.

Emerg Microbes Infect. 2013 Mar;2(3):e15. doi: 10.1038/emi.2013.14. Epub 2013 Mar 27. Review.

23.

Locoregional therapy for cholangiocarcinoma.

Kuhlmann JB, Blum HE.

Curr Opin Gastroenterol. 2013 May;29(3):324-8. doi: 10.1097/MOG.0b013e32835d9dea. Review.

PMID:
23337933
24.

Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope.

Schmidt J, Iversen AK, Tenzer S, Gostick E, Price DA, Lohmann V, Distler U, Bowness P, Schild H, Blum HE, Klenerman P, Neumann-Haefelin C, Thimme R.

PLoS Pathog. 2012;8(11):e1003042. doi: 10.1371/journal.ppat.1003042. Epub 2012 Nov 29.

25.

CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ.

Kang YH, Seigel B, Bengsch B, Fleming VM, Billerbeck E, Simmons R, Walker L, Willberg CB, Barnes EJ, Bhagwanani A, Oo YH, Blum HE, Adams DH, Thimme R, Klenerman P.

Front Immunol. 2012 Nov 20;3:346. doi: 10.3389/fimmu.2012.00346. eCollection 2012.

26.

Selenium levels in patients with hepatitis C virus-related chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma: a pilot study.

Bettinger D, Schultheiss M, Hennecke N, Panther E, Knüppel E, Blum HE, Thimme R, Spangenberg HC.

Hepatology. 2013 Jun;57(6):2543-4. doi: 10.1002/hep.26142. No abstract available.

PMID:
23172787
27.

Factors that determine the antiviral efficacy of HCV-specific CD8(+) T cells ex vivo.

Seigel B, Bengsch B, Lohmann V, Bartenschlager R, Blum HE, Thimme R.

Gastroenterology. 2013 Feb;144(2):426-36. doi: 10.1053/j.gastro.2012.10.047. Epub 2012 Nov 7.

PMID:
23142136
28.

Renal grafts from anti-hepatitis B core-positive donors: a quantitative review of the literature.

Mahboobi N, Tabatabaei SV, Blum HE, Alavian SM.

Transpl Infect Dis. 2012 Oct;14(5):445-51. doi: 10.1111/j.1399-3062.2012.00782.x. Epub 2012 Sep 12. Review.

PMID:
22970743
29.

CD40 inhibits replication of hepatitis C virus in primary human hepatocytes by c-Jun N terminal kinase activation independent from the interferon pathway.

Rau SJ, Hildt E, Himmelsbach K, Thimme R, Wakita T, Blum HE, Fischer R.

Hepatology. 2013 Jan;57(1):23-36. doi: 10.1002/hep.25966.

PMID:
22814930
30.

The transcription factor c-Jun protects against liver damage following activated β-Catenin signaling.

Trierweiler C, Blum HE, Hasselblatt P.

PLoS One. 2012;7(7):e40638. doi: 10.1371/journal.pone.0040638. Epub 2012 Jul 6.

31.

[Direct antiviral treatment strategies in chronic hepatitis C].

Neumann-Haefelin C, Blum HE, Thimme R.

Dtsch Med Wochenschr. 2012 Jun;137(25-26):1360-5. doi: 10.1055/s-0032-1305064. Epub 2012 May 31. Review. German.

PMID:
22653493
32.

Human hepatitis B virus production in avian cells is characterized by enhanced RNA splicing and the presence of capsids containing shortened genomes.

Köck J, Rösler C, Zhang J, Blum HE, Nassal M, Thoma C.

PLoS One. 2012;7(5):e37248. doi: 10.1371/journal.pone.0037248. Epub 2012 May 18.

33.

Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26).

Bengsch B, Seigel B, Flecken T, Wolanski J, Blum HE, Thimme R.

J Immunol. 2012 Jun 1;188(11):5438-47. doi: 10.4049/jimmunol.1103801. Epub 2012 Apr 25.

34.

Low perforin expression of early differentiated HCV-specific CD8+ T cells limits their hepatotoxic potential.

Jo J, Bengsch B, Seigel B, Rau SJ, Schmidt J, Bisse E, Aichele P, Aichele U, Joeckel L, Royer C, Sá Ferreira K, Borner C, Baumert TF, Blum HE, Lohmann V, Fischer R, Thimme R.

J Hepatol. 2012 Jul;57(1):9-16. doi: 10.1016/j.jhep.2012.02.030. Epub 2012 Mar 14.

PMID:
22425625
35.

Differential antigen specificity of hepatitis C virus-specific interleukin 17- and interferon γ-producing CD8(+) T cells during chronic infection.

Grafmueller S, Billerbeck E, Blum HE, Neumann-Haefelin C, Thimme R.

J Infect Dis. 2012 Apr 1;205(7):1142-6. doi: 10.1093/infdis/jis018. Epub 2012 Feb 20.

PMID:
22351943
36.

Diarrhea predicts a positive response to sorafenib in patients with advanced hepatocellular carcinoma.

Bettinger D, Schultheiss M, Knüppel E, Thimme R, Blum HE, Spangenberg HC.

Hepatology. 2012 Aug;56(2):789-90. doi: 10.1002/hep.25637. Epub 2012 Jul 6. No abstract available.

PMID:
22307848
37.

Treatment of unresectable cholangiocarcinoma: conventional transarterial chemoembolization compared with drug eluting bead-transarterial chemoembolization and systemic chemotherapy.

Kuhlmann JB, Euringer W, Spangenberg HC, Breidert M, Blum HE, Harder J, Fischer R.

Eur J Gastroenterol Hepatol. 2012 Apr;24(4):437-43. doi: 10.1097/MEG.0b013e3283502241.

PMID:
22261548
38.

Identification of naturally processed hepatitis C virus-derived major histocompatibility complex class I ligands.

Wölk B, Trautwein C, Büchele B, Kersting N, Blum HE, Rammensee HG, Cerny A, Stevanovic S, Moradpour D, Brass V.

PLoS One. 2012;7(1):e29286. doi: 10.1371/journal.pone.0029286. Epub 2012 Jan 3.

39.

VEGF Trap for the treatment of malignant ascites.

Becker G, Blum HE.

Lancet Oncol. 2012 Feb;13(2):115-6. doi: 10.1016/S1470-2045(11)70394-1. Epub 2011 Dec 20. No abstract available.

PMID:
22192728
40.

Reversible autonomic dysfunction during antiviral treatment in patients with chronic hepatitis C virus infection: Anti-HCV therapy and autonomic function.

Osztovits J, Horvath E, Tax J, Csihi L, Horvath T, Littvay L, Toth T, Abonyi M, Lakatos PL, Kollai M, Feher J, Szalay F, Blum HE.

Hepat Mon. 2011 Feb;11(2):114-8.

41.

Hepatocellular carcinoma: HCC.

Blum HE.

Hepat Mon. 2011 Feb;11(2):69-70. No abstract available.

42.

The transcription factor c-Jun protects against sustained hepatic endoplasmic reticulum stress thereby promoting hepatocyte survival.

Fuest M, Willim K, MacNelly S, Fellner N, Resch GP, Blum HE, Hasselblatt P.

Hepatology. 2012 Feb;55(2):408-18. doi: 10.1002/hep.24699. Epub 2011 Dec 16.

PMID:
21953113
43.

Clinical response to Auron Misheil Therapy in a man with advanced multifocal hepatocellular carcinoma: A case report.

Scheele JS, Harder J, Stankovic Z, Räpple D, Dorn A, Spangenberg HC, Blum HE.

J Med Case Rep. 2011 Sep 24;5:478. doi: 10.1186/1752-1947-5-478.

44.

Gastrointestinal and liver diseases: genetic and epigenetic markers.

Blum HE.

Gut. 2011 Dec;60(12):1630-4. doi: 10.1136/gut.2010.213462. Epub 2011 Sep 2. Review. No abstract available.

PMID:
21890815
45.

Weight loss and severe jaundice in a patient with hyperthyroidism.

Breidert M, Offensperger S, Blum HE, Fischer R.

Z Gastroenterol. 2011 Sep;49(9):1267-9. doi: 10.1055/s-0029-1246059. Epub 2011 Sep 1.

PMID:
21887664
46.

Analysis of bulk and virus-specific CD8+ T cells reveals advanced differentiation of CD8+ T cells in patients with common variable immunodeficiency.

Kuntz M, Goldacker S, Blum HE, Pircher H, Stampf S, Peter HH, Thimme R, Warnatz K.

Clin Immunol. 2011 Nov;141(2):177-86. doi: 10.1016/j.clim.2011.07.006. Epub 2011 Aug 5.

PMID:
21873117
47.

Opioid-induced constipation in advanced illness: safety and efficacy of methylnaltrexone bromide.

Bader S, Jaroslawski K, Blum HE, Becker G.

Clin Med Insights Oncol. 2011;5:201-11. doi: 10.4137/CMO.S4867. Epub 2011 Jul 14.

48.

[Rheumatology today - a dynamic discipline for the patients' good].

Schulze-Koops H, Blum HE.

Dtsch Med Wochenschr. 2011 Aug;136(33):1651. doi: 10.1055/s-0031-1281567. Epub 2011 Aug 10. German. No abstract available.

PMID:
21833883
49.

A severe case of odynophagia.

Kuhlmann JB, Blum HE, Kreisel W, Fischer R.

BMJ. 2011 Jul 13;343:d3137. doi: 10.1136/bmj.d3137. No abstract available.

PMID:
21752845
50.

[A rare cause of an indistinct liver lesion in an elderly woman].

Semmo N, Seuthe B, Er F, Spangenberg HC, Blum HE.

Dtsch Med Wochenschr. 2011 Jun;136(23):1251-4. doi: 10.1055/s-0031-1280545. Epub 2011 May 31. German.

PMID:
21630171

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