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Items: 1 to 50 of 128

1.

TNF receptor 1 deficiency increases regulatory T cell function in nonobese diabetic mice.

Chee J, Angstetra E, Mariana L, Graham KL, Carrington EM, Bluethmann H, Santamaria P, Allison J, Kay TW, Krishnamurthy B, Thomas HE.

J Immunol. 2011 Aug 15;187(4):1702-12. doi: 10.4049/jimmunol.1100511. Epub 2011 Jul 6.

2.

Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.

Rhein V, Song X, Wiesner A, Ittner LM, Baysang G, Meier F, Ozmen L, Bluethmann H, Dröse S, Brandt U, Savaskan E, Czech C, Götz J, Eckert A.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):20057-62. doi: 10.1073/pnas.0905529106. Epub 2009 Nov 6.

3.

Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.

Lambertsen KL, Clausen BH, Babcock AA, Gregersen R, Fenger C, Nielsen HH, Haugaard LS, Wirenfeldt M, Nielsen M, Dagnaes-Hansen F, Bluethmann H, Faergeman NJ, Meldgaard M, Deierborg T, Finsen B.

J Neurosci. 2009 Feb 4;29(5):1319-30. doi: 10.1523/JNEUROSCI.5505-08.2009.

4.

Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model.

Constantin CE, Mair N, Sailer CA, Andratsch M, Xu ZZ, Blumer MJ, Scherbakov N, Davis JB, Bluethmann H, Ji RR, Kress M.

J Neurosci. 2008 May 7;28(19):5072-81. doi: 10.1523/JNEUROSCI.4476-07.2008.

5.

Trace amine-associated receptor 1 modulates dopaminergic activity.

Lindemann L, Meyer CA, Jeanneau K, Bradaia A, Ozmen L, Bluethmann H, Bettler B, Wettstein JG, Borroni E, Moreau JL, Hoener MC.

J Pharmacol Exp Ther. 2008 Mar;324(3):948-56. Epub 2007 Dec 14.

PMID:
18083911
6.

Cutting edge: Modulation of intestinal autoimmunity and IL-2 signaling by sphingosine kinase 2 independent of sphingosine 1-phosphate.

Samy ET, Meyer CA, Caplazi P, Langrish CL, Lora JM, Bluethmann H, Peng SL.

J Immunol. 2007 Nov 1;179(9):5644-8.

7.

Interleukin-1 receptor type 1 is essential for control of cerebral but not systemic listeriosis.

Deckert M, Virna S, Sakowicz-Burkiewicz M, Lütjen S, Soltek S, Bluethmann H, Schlüter D.

Am J Pathol. 2007 Mar;170(3):990-1002.

8.

Obligatory requirement for antibody in recovery from a primary poxvirus infection.

Chaudhri G, Panchanathan V, Bluethmann H, Karupiah G.

J Virol. 2006 Jul;80(13):6339-44. Erratum in: J Virol. 2006 Sep;80(17):8844.

9.

A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction.

Yee BK, Keist R, von Boehmer L, Studer R, Benke D, Hagenbuch N, Dong Y, Malenka RC, Fritschy JM, Bluethmann H, Feldon J, Möhler H, Rudolph U.

Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17154-9. Epub 2005 Nov 11.

11.

Enhancement of the NMDA receptor function by reduction of glycine transporter-1 expression.

Gabernet L, Pauly-Evers M, Schwerdel C, Lentz M, Bluethmann H, Vogt K, Alberati D, Mohler H, Boison D.

Neurosci Lett. 2005 Jan 3;373(1):79-84.

PMID:
15555781
12.
13.

Impaired platelet activation in familial high density lipoprotein deficiency (Tangier disease).

Nofer JR, Herminghaus G, Brodde M, Morgenstern E, Rust S, Engel T, Seedorf U, Assmann G, Bluethmann H, Kehrel BE.

J Biol Chem. 2004 Aug 6;279(32):34032-7. Epub 2004 May 25.

14.

The gamma 2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses.

Schweizer C, Balsiger S, Bluethmann H, Mansuy IM, Fritschy JM, Mohler H, Lüscher B.

Mol Cell Neurosci. 2003 Oct;24(2):442-50.

PMID:
14572465
15.

PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.

Richards JG, Higgins GA, Ouagazzal AM, Ozmen L, Kew JN, Bohrmann B, Malherbe P, Brockhaus M, Loetscher H, Czech C, Huber G, Bluethmann H, Jacobsen H, Kemp JA.

J Neurosci. 2003 Oct 1;23(26):8989-9003.

16.
17.

Requirement for tumor necrosis factor receptor 2 expression on vascular cells to induce experimental cerebral malaria.

Stoelcker B, Hehlgans T, Weigl K, Bluethmann H, Grau GE, Männel DN.

Infect Immun. 2002 Oct;70(10):5857-9.

18.

Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity.

Ballard TM, Pauly-Evers M, Higgins GA, Ouagazzal AM, Mutel V, Borroni E, Kemp JA, Bluethmann H, Kew JN.

J Neurosci. 2002 Aug 1;22(15):6713-23.

19.

Thymus medulla consisting of epithelial islets each derived from a single progenitor.

Rodewald HR, Paul S, Haller C, Bluethmann H, Blum C.

Nature. 2001 Dec 13;414(6865):763-8.

PMID:
11742403
20.

Interleukin-6 (IL6) and cellular response to facial nerve injury: effects on lymphocyte recruitment, early microglial activation and axonal outgrowth in IL6-deficient mice.

Galiano M, Liu ZQ, Kalla R, Bohatschek M, Koppius A, Gschwendtner A, Xu S, Werner A, Kloss CU, Jones LL, Bluethmann H, Raivich G.

Eur J Neurosci. 2001 Jul;14(2):327-41.

PMID:
11553283
21.
22.

Aged mice exhibit in vivo defective peripheral clonal deletion of D(b)/H-Y reactive CD8(+) T cells.

Hsu HC, Zhou T, Shi J, Yang PA, Liu D, Zhang HG, Bluethmann H, Mountz JD.

Mech Ageing Dev. 2001 Mar;122(3):305-26.

PMID:
11311318
23.

MHC-II-independent CD4+ T cells induce colitis in immunodeficient RAG-/- hosts.

Trobonjaca Z, Leithäuser F, Möller P, Bluethmann H, Koezuka Y, MacDonald HR, Reimann J.

J Immunol. 2001 Mar 15;166(6):3804-12.

24.

Molecular and neuronal substrate for the selective attenuation of anxiety.

Löw K, Crestani F, Keist R, Benke D, Brünig I, Benson JA, Fritschy JM, Rülicke T, Bluethmann H, Möhler H, Rudolph U.

Science. 2000 Oct 6;290(5489):131-4. Erratum in: Science 2000 Nov 3;290(5493):936c.

25.
26.

Enterotoxin adjuvants have direct effects on T cells and antigen-presenting cells that result in either interleukin-4-dependent or -independent immune responses.

Yamamoto M, Kiyono H, Kweon MN, Yamamoto S, Fujihashi K, Kurazono H, Imaoka K, Bluethmann H, Takahashi I, Takeda Y, Azuma M, McGhee JR.

J Infect Dis. 2000 Jul;182(1):180-90. Epub 2000 Jun 30.

PMID:
10882596
27.

Metallothionein induction by restraint stress: role of glucocorticoids and IL-6.

Hernández J, Carrasco J, Belloso E, Giralt M, Bluethmann H, Kee Lee D, Andrews GK, Hidalgo J.

Cytokine. 2000 Jun;12(6):791-6.

PMID:
10843766
28.

Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site.

Kew JN, Koester A, Moreau JL, Jenck F, Ouagazzal AM, Mutel V, Richards JG, Trube G, Fischer G, Montkowski A, Hundt W, Reinscheid RK, Pauly-Evers M, Kemp JA, Bluethmann H.

J Neurosci. 2000 Jun 1;20(11):4037-49.

29.

Alternate mucosal immune system: organized Peyer's patches are not required for IgA responses in the gastrointestinal tract.

Yamamoto M, Rennert P, McGhee JR, Kweon MN, Yamamoto S, Dohi T, Otake S, Bluethmann H, Fujihashi K, Kiyono H.

J Immunol. 2000 May 15;164(10):5184-91.

30.

Tumor necrosis factor induces tumor necrosis via tumor necrosis factor receptor type 1-expressing endothelial cells of the tumor vasculature.

Stoelcker B, Ruhland B, Hehlgans T, Bluethmann H, Luther T, Männel DN.

Am J Pathol. 2000 Apr;156(4):1171-6.

31.

Stress-induced enhancement of skin immune function: A role for gamma interferon.

Dhabhar FS, Satoskar AR, Bluethmann H, David JR, McEwen BS.

Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2846-51.

32.

Interleukin-4-deficient BALB/c mice develop an enhanced Th1-like response but control cardiac inflammation following Borrelia burgdorferi infection.

Satoskar AR, Elizondo J, Monteforte GM, Stamm LM, Bluethmann H, Katavolos P, Telford SR 3rd.

FEMS Microbiol Lett. 2000 Feb 15;183(2):319-25.

33.

Antiviral B cell memory in the absence of mature follicular dendritic cell networks and classical germinal centers in TNFR1-/- mice.

Karrer U, López-Macías C, Oxenius A, Odermatt B, Bachmann MF, Kalinke U, Bluethmann H, Hengartner H, Zinkernagel RM.

J Immunol. 2000 Jan 15;164(2):768-78.

34.

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

Rudolph U, Crestani F, Benke D, Brünig I, Benson JA, Fritschy JM, Martin JR, Bluethmann H, Möhler H.

Nature. 1999 Oct 21;401(6755):796-800. Erratum in: Nature 2000 Apr 6;404(6778):629.

PMID:
10548105
35.

The lectin-like domain of tumor necrosis factor-alpha increases membrane conductance in microvascular endothelial cells and peritoneal macrophages.

Hribar M, Bloc A, van der Goot FG, Fransen L, De Baetselier P, Grau GE, Bluethmann H, Matthay MA, Dunant Y, Pugin J, Lucas R.

Eur J Immunol. 1999 Oct;29(10):3105-11.

36.

Postsynaptic clustering of gamma-aminobutyric acid type A receptors by the gamma3 subunit in vivo.

Baer K, Essrich C, Benson JA, Benke D, Bluethmann H, Fritschy JM, Lüscher B.

Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12860-5.

37.

TNF is essential for the cell-mediated protective immunity induced by the radiation-attenuated schistosome vaccine.

Street M, Coulson PS, Sadler C, Warnock LJ, McLaughlin D, Bluethmann H, Wilson RA.

J Immunol. 1999 Oct 15;163(8):4489-94.

38.

Neonatal lethality in mice deficient in XCE, a novel member of the endothelin-converting enzyme and neutral endopeptidase family.

Schweizer A, Valdenaire O, Köster A, Lang Y, Schmitt G, Lenz B, Bluethmann H, Rohrer J.

J Biol Chem. 1999 Jul 16;274(29):20450-6.

39.

Mutations affecting either generation or survival of cells influence the pool size of mature B cells.

Rolink AG, Brocker T, Bluethmann H, Kosco-Vilbois MH, Andersson J, Melchers F.

Immunity. 1999 May;10(5):619-28.

40.

Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.

Weber P, Bartsch U, Rasband MN, Czaniera R, Lang Y, Bluethmann H, Margolis RU, Levinson SR, Shrager P, Montag D, Schachner M.

J Neurosci. 1999 Jun 1;19(11):4245-62.

42.

Severity of symptoms and demyelination in MOG-induced EAE depends on TNFR1.

Eugster HP, Frei K, Bachmann R, Bluethmann H, Lassmann H, Fontana A.

Eur J Immunol. 1999 Feb;29(2):626-32.

43.

Development and function of autospecific dual TCR+ T lymphocytes.

Paterson RK, Bluethmann H, Tseng P, Dunlap A, Finkel TH.

Int Immunol. 1999 Jan;11(1):113-9.

PMID:
10050679
44.

Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice.

Penkowa M, Moos T, Carrasco J, Hadberg H, Molinero A, Bluethmann H, Hidalgo J.

Glia. 1999 Feb 15;25(4):343-57.

PMID:
10028917
45.

Multivalent structure of an alphabetaT cell receptor.

Fernández-Miguel G, Alarcón B, Iglesias A, Bluethmann H, Alvarez-Mon M, Sanz E, de la Hera A.

Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1547-52.

46.

Induction of specific T cell tolerance by Fas ligand-expressing antigen-presenting cells.

Zhang HG, Su X, Liu D, Liu W, Yang P, Wang Z, Edwards CK, Bluethmann H, Mountz JD, Zhou T.

J Immunol. 1999 Feb 1;162(3):1423-30.

47.

Prolonged contraction-relaxation cycle of fast-twitch muscles in parvalbumin knockout mice.

Schwaller B, Dick J, Dhoot G, Carroll S, Vrbova G, Nicotera P, Pette D, Wyss A, Bluethmann H, Hunziker W, Celio MR.

Am J Physiol. 1999 Feb;276(2):C395-403. doi: 10.1152/ajpcell.1999.276.2.C395.

PMID:
9950767
48.

IL-6 deficiency leads to increased emotionality in mice: evidence in transgenic mice carrying a null mutation for IL-6.

Armario A, Hernández J, Bluethmann H, Hidalgo J.

J Neuroimmunol. 1998 Dec 1;92(1-2):160-9.

PMID:
9916891
49.

In vivo hepatocyte proliferation is inducible through a TNF and IL-6-independent pathway.

Ledda-Columbano GM, Curto M, Piga R, Zedda AI, Menegazzi M, Sartori C, Shinozuka H, Bluethmann H, Poli V, Ciliberto G, Columbano A.

Oncogene. 1998 Aug 27;17(8):1039-44.

50.

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