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Items: 11


The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44.

Zhao C, Thompson BJ, Chen K, Gao F, Blouw B, Marella M, Zimmerman S, Kimbler T, Garrovillo S, Bahn J, Huang L, Huang Z, Shepard HM, Rosengren S, Thanos CD, Maneval DC.

Oncotarget. 2019 Nov 12;10(61):6561-6576. doi: 10.18632/oncotarget.27302. eCollection 2019 Nov 12.


Remodeling the Tumor Microenvironment Sensitizes Breast Tumors to Anti-Programmed Death-Ligand 1 Immunotherapy.

Clift R, Souratha J, Garrovillo SA, Zimmerman S, Blouw B.

Cancer Res. 2019 Aug 15;79(16):4149-4159. doi: 10.1158/0008-5472.CAN-18-3060. Epub 2019 Jun 27.


Dissecting the Stromal Signaling and Regulation of Myeloid Cells and Memory Effector T Cells in Pancreatic Cancer.

Blair AB, Kim VM, Muth ST, Saung MT, Lokker N, Blouw B, Armstrong TD, Jaffee EM, Tsujikawa T, Coussens LM, He J, Burkhart RA, Wolfgang CL, Zheng L.

Clin Cancer Res. 2019 Sep 1;25(17):5351-5363. doi: 10.1158/1078-0432.CCR-18-4192. Epub 2019 Jun 11.


Dynamic Contrast-enhanced MRI Detects Responses to Stroma-directed Therapy in Mouse Models of Pancreatic Ductal Adenocarcinoma.

Cao J, Pickup S, Clendenin C, Blouw B, Choi H, Kang D, Rosen M, O'Dwyer PJ, Zhou R.

Clin Cancer Res. 2019 Apr 1;25(7):2314-2322. doi: 10.1158/1078-0432.CCR-18-2276. Epub 2018 Dec 26.


Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression.

Li X, Shepard HM, Cowell JA, Zhao C, Osgood RJ, Rosengren S, Blouw B, Garrovillo SA, Pagel MD, Whatcott CJ, Han H, Von Hoff DD, Taverna DM, LaBarre MJ, Maneval DC, Thompson CB.

Clin Cancer Res. 2018 Oct 1;24(19):4798-4807. doi: 10.1158/1078-0432.CCR-17-3284. Epub 2018 Jul 3.


The invadopodia scaffold protein Tks5 is required for the growth of human breast cancer cells in vitro and in vivo.

Blouw B, Patel M, Iizuka S, Abdullah C, You WK, Huang X, Li JL, Diaz B, Stallcup WB, Courtneidge SA.

PLoS One. 2015 Mar 31;10(3):e0121003. doi: 10.1371/journal.pone.0121003. eCollection 2015.


The induction of HIF-1 reduces astrocyte activation by amyloid beta peptide.

Schubert D, Soucek T, Blouw B.

Eur J Neurosci. 2009 Apr;29(7):1323-34. doi: 10.1111/j.1460-9568.2009.06712.x. Epub 2009 Mar 23.


A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo.

Blouw B, Seals DF, Pass I, Diaz B, Courtneidge SA.

Eur J Cell Biol. 2008 Sep;87(8-9):555-67. doi: 10.1016/j.ejcb.2008.02.008. Epub 2008 Apr 15.


Loss of vascular endothelial growth factor expression reduces vascularization, but not growth, of tumors lacking the Von Hippel-Lindau tumor suppressor gene.

Blouw B, Haase VH, Song H, Bergers G, Johnson RS.

Oncogene. 2007 Jul 5;26(31):4531-40. Epub 2007 Feb 5.


Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage.

Helton R, Cui J, Scheel JR, Ellison JA, Ames C, Gibson C, Blouw B, Ouyang L, Dragatsis I, Zeitlin S, Johnson RS, Lipton SA, Barlow C.

J Neurosci. 2005 Apr 20;25(16):4099-107. Erratum in: J Neurosci. 2005 May 11;25(19):1 p following 4888.


The hypoxic response of tumors is dependent on their microenvironment.

Blouw B, Song H, Tihan T, Bosze J, Ferrara N, Gerber HP, Johnson RS, Bergers G.

Cancer Cell. 2003 Aug;4(2):133-46.

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