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Items: 33


Low-Grade Surface Osteosarcoma of the Temporal Bone in Paediatric Patients: A Case Report and Literature Review.

Villemure-Poliquin N, Trudel M, Labonté S, Blouin V, Fradet G.

Clin Med Insights Pediatr. 2019 Jun 26;13:1179556519855381. doi: 10.1177/1179556519855381. eCollection 2019.


Stability of the adeno-associated virus 8 reference standard material.

Penaud-Budloo M, Broucque F, Harrouet K, Bouzelha M, Saleun S, Douthe S, D'Costa S, Ogram S, Adjali O, Blouin V, Lock M, Snyder RO, Ayuso E.

Gene Ther. 2019 May;26(5):211-215. doi: 10.1038/s41434-019-0072-9. Epub 2019 Mar 29.


Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls.

François A, Bouzelha M, Lecomte E, Broucque F, Penaud-Budloo M, Adjali O, Moullier P, Blouin V, Ayuso E.

Mol Ther Methods Clin Dev. 2018 Jul 27;10:223-236. doi: 10.1016/j.omtm.2018.07.004. eCollection 2018 Sep 21.


Accurate Identification and Quantification of DNA Species by Next-Generation Sequencing in Adeno-Associated Viral Vectors Produced in Insect Cells.

Penaud-Budloo M, Lecomte E, Guy-Duché A, Saleun S, Roulet A, Lopez-Roques C, Tournaire B, Cogné B, Léger A, Blouin V, Lindenbaum P, Moullier P, Ayuso E.

Hum Gene Ther Methods. 2017 Jun;28(3):148-162. doi: 10.1089/hgtb.2016.185. Epub 2017 Apr 21.


AAV-ID: A Rapid and Robust Assay for Batch-to-Batch Consistency Evaluation of AAV Preparations.

Pacouret S, Bouzelha M, Shelke R, Andres-Mateos E, Xiao R, Maurer A, Mevel M, Turunen H, Barungi T, Penaud-Budloo M, Broucque F, Blouin V, Moullier P, Ayuso E, Vandenberghe LH.

Mol Ther. 2017 Jun 7;25(6):1375-1386. doi: 10.1016/j.ymthe.2017.04.001. Epub 2017 Apr 17.


Efficient CNS targeting in adult mice by intrathecal infusion of single-stranded AAV9-GFP for gene therapy of neurological disorders.

Bey K, Ciron C, Dubreil L, Deniaud J, Ledevin M, Cristini J, Blouin V, Aubourg P, Colle MA.

Gene Ther. 2017 May;24(5):325-332. doi: 10.1038/gt.2017.18. Epub 2017 Apr 20.


A fragmented adeno-associated viral dual vector strategy for treatment of diseases caused by mutations in large genes leads to expression of hybrid transcripts.

McClements ME, Charbel Issa P, Blouin V, MacLaren RE.

J Genet Syndr Gene Ther. 2016 Nov 14;7(5). pii: 311. doi: 10.4172/2157-7412.1000311.


An AAVrh10-CAG-CYP21-HA vector allows persistent correction of 21-hydroxylase deficiency in a Cyp21-/- mouse model.

Perdomini M, Dos Santos C, Goumeaux C, Blouin V, Bougnères P.

Gene Ther. 2017 May;24(5):275-281. doi: 10.1038/gt.2017.10. Epub 2017 Feb 6.


Seipin deficiency alters brown adipose tissue thermogenesis and insulin sensitivity in a non-cell autonomous mode.

Dollet L, Magré J, Joubert M, Le May C, Ayer A, Arnaud L, Pecqueur C, Blouin V, Cariou B, Prieur X.

Sci Rep. 2016 Oct 17;6:35487. doi: 10.1038/srep35487.


Vitrectomy Before Intravitreal Injection of AAV2/2 Vector Promotes Efficient Transduction of Retinal Ganglion Cells in Dogs and Nonhuman Primates.

Tshilenge KT, Ameline B, Weber M, Mendes-Madeira A, Nedellec S, Biget M, Provost N, Libeau L, Blouin V, Deschamps JY, Le Meur G, Colle MA, Moullier P, Pichard V, Rolling F.

Hum Gene Ther Methods. 2016 Jun;27(3):122-34. doi: 10.1089/hgtb.2016.034.


Practical utilization of recombinant AAV vector reference standards: focus on vector genomes titration by free ITR qPCR.

D'Costa S, Blouin V, Broucque F, Penaud-Budloo M, François A, Perez IC, Le Bec C, Moullier P, Snyder RO, Ayuso E.

Mol Ther Methods Clin Dev. 2016 Mar 30;5:16019. doi: 10.1038/mtm.2016.19. eCollection 2016.


Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing.

Lecomte E, Tournaire B, Cogné B, Dupont JB, Lindenbaum P, Martin-Fontaine M, Broucque F, Robin C, Hebben M, Merten OW, Blouin V, François A, Redon R, Moullier P, Léger A.

Mol Ther Nucleic Acids. 2015 Oct 27;4:e260. doi: 10.1038/mtna.2015.32.


Use of Adeno-Associated Virus to Enrich Cardiomyocytes Derived from Human Stem Cells.

Guan X, Wang Z, Czerniecki S, Mack D, François V, Blouin V, Moullier P, Childers MK.

Hum Gene Ther Clin Dev. 2015 Sep;26(3):194-201. doi: 10.1089/humc.2015.052. Epub 2015 Aug 7.


Use of adeno-associated virus to enrich cardiomyocytes derived from human stem cells.

Guan X, Wang Z, Czerniecki S, Mack D, François V, Blouin V, Moullier P, Childers M.

Hum Gene Ther Clin Dev. 2015 Jul 15. [Epub ahead of print]


Efficient central nervous system AAVrh10-mediated intrathecal gene transfer in adult and neonate rats.

Hordeaux J, Dubreil L, Deniaud J, Iacobelli F, Moreau S, Ledevin M, Le Guiner C, Blouin V, Le Duff J, Mendes-Madeira A, Rolling F, Cherel Y, Moullier P, Colle MA.

Gene Ther. 2015 Apr;22(4):316-24. doi: 10.1038/gt.2014.121. Epub 2015 Jan 15.


Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material.

Ayuso E, Blouin V, Lock M, McGorray S, Leon X, Alvira MR, Auricchio A, Bucher S, Chtarto A, Clark KR, Darmon C, Doria M, Fountain W, Gao G, Gao K, Giacca M, Kleinschmidt J, Leuchs B, Melas C, Mizukami H, Müller M, Noordman Y, Bockstael O, Ozawa K, Pythoud C, Sumaroka M, Surosky R, Tenenbaum L, van der Linden I, Weins B, Wright JF, Zhang X, Zentilin L, Bosch F, Snyder RO, Moullier P.

Hum Gene Ther. 2014 Nov;25(11):977-87. doi: 10.1089/hum.2014.057.


Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates.

Chuah MK, Petrus I, De Bleser P, Le Guiner C, Gernoux G, Adjali O, Nair N, Willems J, Evens H, Rincon MY, Matrai J, Di Matteo M, Samara-Kuko E, Yan B, Acosta-Sanchez A, Meliani A, Cherel G, Blouin V, Christophe O, Moullier P, Mingozzi F, VandenDriessche T.

Mol Ther. 2014 Sep;22(9):1605-13. doi: 10.1038/mt.2014.114. Epub 2014 Jun 23.


Different protein composition and functional properties of adeno-associated virus-6 vector manufactured from the culture medium and cell lysates.

Denard J, Jenny C, Blouin V, Moullier P, Svinartchouk F.

Mol Ther Methods Clin Dev. 2014 Jul 30;1:14031. doi: 10.1038/mtm.2014.31. eCollection 2014.


Prony series spectra of structural relaxation in N-BK7 for finite element modeling.

Koontz E, Blouin V, Wachtel P, Musgraves JD, Richardson K.

J Phys Chem A. 2012 Dec 20;116(50):12198-205. doi: 10.1021/jp307717q. Epub 2012 Dec 6.


Translational research to reduce trans-fat intakes in Northern Québec (Nunavik) Inuit communities: a success story?

Counil É, Gauthier MJ, Blouin V, Grey M, Angiyou E, Kauki T, Dewailly É.

Int J Circumpolar Health. 2012 Jul 20;71:18833. doi: 10.3402/ijch.v71i0.18833.


MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV.

Sudres M, Ciré S, Vasseur V, Brault L, Da Rocha S, Boisgérault F, Le Bec C, Gross DA, Blouin V, Ryffel B, Galy A.

Mol Ther. 2012 Aug;20(8):1571-81. doi: 10.1038/mt.2012.101. Epub 2012 May 29.


Production and purification of recombinant adeno-associated vectors.

Wang L, Blouin V, Brument N, Bello-Roufai M, Francois A.

Methods Mol Biol. 2011;807:361-404. doi: 10.1007/978-1-61779-370-7_16.


Adeno-associated virus capsid serotype identification: Analytical methods development and application.

Van Vliet K, Mohiuddin Y, McClung S, Blouin V, Rolling F, Moullier P, Agbandje-McKenna M, Snyder RO.

J Virol Methods. 2009 Aug;159(2):167-77. doi: 10.1016/j.jviromet.2009.03.020. Epub 2009 Mar 26.


The role of the adeno-associated virus capsid in gene transfer.

Van Vliet KM, Blouin V, Brument N, Agbandje-McKenna M, Snyder RO.

Methods Mol Biol. 2008;437:51-91. doi: 10.1007/978-1-59745-210-6_2. Review.


Proteolytic mapping of the adeno-associated virus capsid.

Van Vliet K, Blouin V, Agbandje-McKenna M, Snyder RO.

Mol Ther. 2006 Dec;14(6):809-21. Epub 2006 Sep 27.


Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines.

Toublanc E, Benraiss A, Bonnin D, Blouin V, Brument N, Cartier N, Epstein AL, Moullier P, Salvetti A.

J Gene Med. 2004 May;6(5):555-64.


Improving rAAV production and purification: towards the definition of a scaleable process.

Blouin V, Brument N, Toublanc E, Raimbaud I, Moullier P, Salvetti A.

J Gene Med. 2004 Feb;6 Suppl 1:S223-8. Review.


A versatile and scalable two-step ion-exchange chromatography process for the purification of recombinant adeno-associated virus serotypes-2 and -5.

Brument N, Morenweiser R, Blouin V, Toublanc E, Raimbaud I, Chérel Y, Folliot S, Gaden F, Boulanger P, Kroner-Lux G, Moullier P, Rolling F, Salvetti A.

Mol Ther. 2002 Nov;6(5):678-86.


Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus.

Favre D, Blouin V, Provost N, Spisek R, Porrot F, Bohl D, Marmé F, Chérel Y, Salvetti A, Hurtrel B, Heard JM, Rivière Y, Moullier P.

J Virol. 2002 Nov;76(22):11605-11.


Recombinant adeno-associated virus type 2 mediates highly efficient gene transfer in regenerating rat skeletal muscle.

Abadie J, Blouin V, Guigand L, Wyers M, Cherel Y.

Gene Ther. 2002 Aug;9(15):1037-43.


Immediate and long-term safety of recombinant adeno-associated virus injection into the nonhuman primate muscle.

Favre D, Provost N, Blouin V, Blancho G, Chérel Y, Salvetti A, Moullier P.

Mol Ther. 2001 Dec;4(6):559-66.


Hyaluronidase enhances recombinant adeno-associated virus (rAAV)-mediated gene transfer in the rat skeletal muscle.

Favre D, Cherel Y, Provost N, Blouin V, Ferry N, Moullier P, Salvetti A.

Gene Ther. 2000 Aug;7(16):1417-20.


[Evaluation of recombinant retrovirus and adenovirus for gene transfer to normal and pathologic intestinal tissue].

Laine F, Blouin V, Ferry N.

Gastroenterol Clin Biol. 1999 Feb;23(2):221-8. French.

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