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Validation and impact of a simplified clinical decision rule for diagnosing pulmonary embolism in primary care: design of the PECAN prospective diagnostic cohort management study.

van Maanen R, Rutten FH, Klok FA, Huisman MV, Blom JW, Moons KGM, Geersing GJ.

BMJ Open. 2019 Oct 10;9(10):e031639. doi: 10.1136/bmjopen-2019-031639.


Changes in patient satisfaction related to their perceived health state during implementation of improved integrated care for older persons.

Poot AJ, Wopereis DM, den Elzen WPJ, Gussekloo J, Blom JW.

PLoS One. 2019 May 16;14(5):e0216028. doi: 10.1371/journal.pone.0216028. eCollection 2019.


Effects of a clinical medication review focused on personal goals, quality of life, and health problems in older persons with polypharmacy: A randomised controlled trial (DREAMeR-study).

Verdoorn S, Kwint HF, Blom JW, Gussekloo J, Bouvy ML.

PLoS Med. 2019 May 8;16(5):e1002798. doi: 10.1371/journal.pmed.1002798. eCollection 2019 May.


Systolic Blood Pressure and Cognitive Decline in Older Adults With Hypertension.

Streit S, Poortvliet RKE, Elzen WPJD, Blom JW, Gussekloo J.

Ann Fam Med. 2019 Mar;17(2):100-107. doi: 10.1370/afm.2367.


Incidence of sight-threatening diabetic retinopathy in people with Type 2 diabetes mellitus and numbers needed to screen: a systematic review.

Groeneveld Y, Tavenier D, Blom JW, Polak BCP.

Diabet Med. 2019 Jan 24. doi: 10.1111/dme.13908. [Epub ahead of print] Review.


Evidence supporting the best clinical management of patients with multimorbidity and polypharmacy: a systematic guideline review and expert consensus.

Muth C, Blom JW, Smith SM, Johnell K, Gonzalez-Gonzalez AI, Nguyen TS, Brueckle MS, Cesari M, Tinetti ME, Valderas JM.

J Intern Med. 2019 Mar;285(3):272-288. doi: 10.1111/joim.12842. Epub 2018 Dec 10. Erratum in: J Intern Med. 2019 Oct;286(4):487.


Development of a Patient-Reported Outcome Measure for Geriatric Care: The Older Persons and Informal Caregivers Survey Short Form.

Santoso AMM, Lutomski JE, Hofman CS, Metzelthin SF, Blom JW, van der Wees PJ, Olde Rikkert MGM, Melis RJF; TOPICS-MDS Consortium.

Value Health. 2018 Oct;21(10):1198-1204. doi: 10.1016/j.jval.2018.02.011. Epub 2018 Apr 11.


Effects of discontinuation of chronic medication in primary care: a systematic review of deprescribing trials.

Thio SL, Nam J, van Driel ML, Dirven T, Blom JW.

Br J Gen Pract. 2018 Oct;68(675):e663-e672. doi: 10.3399/bjgp18X699041.


The effectiveness of functional task exercise and physical therapy as prevention of functional decline in community dwelling older people with complex health problems.

Siemonsma PC, Blom JW, Hofstetter H, van Hespen ATH, Gussekloo J, Drewes YM, van Meeteren NLU.

BMC Geriatr. 2018 Jul 17;18(1):164. doi: 10.1186/s12877-018-0859-3.


Wishes and needs of community-dwelling older persons concerning general practice: A qualitative study.

van Blijswijk SCE, de Waard CS, van Peet PG, Keizer D, von Faber M, de Waal MWM, den Elzen WPJ, Gussekloo J, Blom JW.

PLoS One. 2018 Jul 17;13(7):e0200614. doi: 10.1371/journal.pone.0200614. eCollection 2018.


Prediction of functional decline in community-dwelling older persons in general practice: a cohort study.

van Blijswijk SCE, Blom JW, de Craen AJM, den Elzen WPJ, Gussekloo J.

BMC Geriatr. 2018 Jun 11;18(1):140. doi: 10.1186/s12877-018-0826-z.


The frail older person does not exist: development of frailty profiles with latent class analysis.

Looman WM, Fabbricotti IN, Blom JW, Jansen APD, Lutomski JE, Metzelthin SF, Huijsman R; TOPICS-MDS Research Consortium.

BMC Geriatr. 2018 Apr 4;18(1):84. doi: 10.1186/s12877-018-0776-5.


Deprescribing preventive cardiovascular medication in patients with predicted low cardiovascular disease risk in general practice - the ECSTATIC study: a cluster randomised non-inferiority trial.

Luymes CH, Poortvliet RKE, van Geloven N, de Waal MWM, Drewes YM, Blom JW, Smidt N, Assendelft WJJ, van den Hout WB, de Ruijter W, Numans ME.

BMC Med. 2018 Jan 11;16(1):5. doi: 10.1186/s12916-017-0988-0.


Unravelling complex primary-care programs to maintain independent living in older people: a systematic overview.

Smit LC, Schuurmans MJ, Blom JW, Fabbricotti IN, Jansen APD, Kempen GIJM, Koopmans R, Looman WM, Melis RJF, Metzelthin SF, Moll van Charante EP, Muntinga ME, Ruikes FGH, Spoorenberg SLW, Suijker JJ, Wynia K, Gussekloo J, De Wit NJ, Bleijenberg N.

J Clin Epidemiol. 2018 Apr;96:110-119. doi: 10.1016/j.jclinepi.2017.12.013. Epub 2017 Dec 28.


Functional Impairment and Risk of Venous Thrombosis in Older Adults.

Engbers MJ, Blom JW, Cushman M, Rosendaal FR, van Hylckama Vlieg A.

J Am Geriatr Soc. 2017 Sep;65(9):2003-2008. doi: 10.1111/jgs.14964. Epub 2017 Jun 9.


Incidental findings in research: A focus group study about the perspective of the research participant.

de Boer AW, Drewes YM, de Mutsert R, Numans ME, den Heijer M, Dekkers OM, de Roos A, Lamb HJ, Blom JW, Reis R.

J Magn Reson Imaging. 2018 Jan;47(1):230-237. doi: 10.1002/jmri.25739. Epub 2017 May 4.


Treatment duration of febrile urinary tract infection: a pragmatic randomized, double-blind, placebo-controlled non-inferiority trial in men and women.

van Nieuwkoop C, van der Starre WE, Stalenhoef JE, van Aartrijk AM, van der Reijden TJ, Vollaard AM, Delfos NM, van 't Wout JW, Blom JW, Spelt IC, Leyten EM, Koster T, Ablij HC, van der Beek MT, Knol MJ, van Dissel JT.

BMC Med. 2017 Apr 3;15(1):70. doi: 10.1186/s12916-017-0835-3.


Statin Use and Self-Reported Hindering Muscle Complaints in Older Persons: A Population Based Study.

van der Ploeg MA, Poortvliet RK, van Blijswijk SC, den Elzen WP, van Peet PG, de Ruijter W, Blom JW, Gussekloo J.

PLoS One. 2016 Dec 2;11(12):e0166857. doi: 10.1371/journal.pone.0166857. eCollection 2016.


[Coping strategies of older people with low mood].

von Faber M, van der Weele GM, van der Geest G, Blom JW, van der Zouwe N, Reis R, van der Mast RC, Gussekloo J.

Tijdschr Gerontol Geriatr. 2016 Dec;47(6):249-257. Epub 2016 Nov 9. Dutch.


Problems experienced by informal caregivers with older care recipients with and without cognitive impairment.

Van Bruggen S, Gussekloo J, Bode C, Touwen DP, Engberts DP, Blom JW.

Home Health Care Serv Q. 2016 Jan-Mar;35(1):11-24. doi: 10.1080/01621424.2016.1145166. Epub 2016 Mar 28.


Drug prescription rates in secondary cardiovascular prevention in old age: Do vulnerability and severity of the history of cardiovascular disease matter?

van Peet PG, Gussekloo J, den Elzen WP, Blom JW, de Waal MW, de Ruijter W.

Scand J Prim Health Care. 2015;33(4):260-8. doi: 10.3109/02813432.2015.1117281.


Older people coping with low mood: a qualitative study.

von Faber M, van der Geest G, van der Weele GM, Blom JW, van der Mast RC, Reis R, Gussekloo J.

Int Psychogeriatr. 2016 Apr;28(4):603-12. doi: 10.1017/S1041610215002264. Epub 2015 Dec 17.


Advantages and disadvantages of unstructured cardiovascular risk factor screening for follow-up in primary care.

de Boer AW, de Mutsert R, den Heijer M, Rosendaal FR, Jukema JW, Blom JW, Numans ME; NEO study group.

Eur J Prev Cardiol. 2016 Jul;23(11):1195-201. doi: 10.1177/2047487315618794. Epub 2015 Nov 24.


Survey Mode Biases Reporting of Activities of Daily Living and Instrumental Activities of Daily Living.

Lutomski JE, Krabbe PF, Bleijenberg N, Blom JW, Buurman BM, Kempen GI, Muntinga ME, Steyerberg EW, Olde Rikkert MG, Melis RJ.

J Am Geriatr Soc. 2015 Nov;63(11):2419-21. doi: 10.1111/jgs.13797. No abstract available.


Self-Reported Hindering Health Complaints of Community-Dwelling Older Persons: A Cross-Sectional Study.

van Blijswijk SC, Chan OY, van Houwelingen AH, Gussekloo J, den Elzen WP, Blom JW.

PLoS One. 2015 Nov 16;10(11):e0142416. doi: 10.1371/journal.pone.0142416. eCollection 2015.


Overweight can be used as a tool to guide case-finding for cardiovascular risk assessment.

de Boer AW, de Mutsert R, den Heijer M, Jukema JW, Rosendaal FR, Blom JW, Assendelft WJ; NEO study group.

Fam Pract. 2015 Dec;32(6):646-51. doi: 10.1093/fampra/cmv080. Epub 2015 Oct 17.


Change in calculated cardiovascular risk due to guideline revision: A cross-sectional study in the Netherlands.

Luymes CH, de Ruijter W, Poortvliet RK, Putter H, van Duijn HJ, Numans ME, Drewes YM, Blom JW, Assendelft WJ.

Eur J Gen Pract. 2015;21(4):217-23. doi: 10.3109/13814788.2015.1064389. Epub 2015 Jul 31.


Clinical features of venous insufficiency and the risk of venous thrombosis in older people.

Engbers MJ, Karasu A, Blom JW, Cushman M, Rosendaal FR, van Hylckama Vlieg A.

Br J Haematol. 2015 Nov;171(3):417-23. doi: 10.1111/bjh.13579. Epub 2015 Jul 27.


Correction: Predictive Value of a Profile of Routine Blood Measurements on Mortality in Older Persons in the General Population: The Leiden 85-Plus Study.

van Houwelingen AH, den Elzen WP, Mooijaart SP, Heijmans M, Blom JW, de Craen AJ, Gussekloo J.

PLoS One. 2015 Jun 9;10(6):e0129985. doi: 10.1371/journal.pone.0129985. eCollection 2015. No abstract available.


Consequences of interaction of functional, somatic, mental and social problems in community-dwelling older people.

van Houwelingen AH, den Elzen WP, le Cessie S, Blom JW, Gussekloo J.

PLoS One. 2015 Apr 21;10(4):e0121013. doi: 10.1371/journal.pone.0121013. eCollection 2015.


Comparing the health state preferences of older persons, informal caregivers and healthcare professionals: a vignette study.

Hofman CS, Makai P, Blom JW, Boter H, Buurman BM, Olde Rikkert MG, Donders R, Melis RJ.

PLoS One. 2015 Mar 4;10(3):e0119197. doi: 10.1371/journal.pone.0119197. eCollection 2015.


Reporting of patient-centred outcomes in heart failure trials: are patient preferences being ignored?

Blom JW, El Azzi M, Wopereis DM, Glynn L, Muth C, van Driel ML.

Heart Fail Rev. 2015 Jul;20(4):385-92. doi: 10.1007/s10741-015-9476-9. Review.


The Ariadne principles: how to handle multimorbidity in primary care consultations.

Muth C, van den Akker M, Blom JW, Mallen CD, Rochon J, Schellevis FG, Becker A, Beyer M, Gensichen J, Kirchner H, Perera R, Prados-Torres A, Scherer M, Thiem U, van den Bussche H, Glasziou PP.

BMC Med. 2014 Dec 8;12:223. doi: 10.1186/s12916-014-0223-1.


Variability in vulnerability assessment of older people by individual general practitioners: a cross-sectional study.

Drewes YM, Blom JW, Assendelft WJ, Stijnen T, den Elzen WP, Gussekloo J.

PLoS One. 2014 Nov 7;9(11):e108666. doi: 10.1371/journal.pone.0108666. eCollection 2014.


A postal screener for pain and need for treatment in older persons in primary care.

de Waal MW, den Elzen WP, Achterberg WP, Gussekloo J, Blom JW.

J Am Geriatr Soc. 2014 Oct;62(10):1832-7. doi: 10.1111/jgs.13064. Epub 2014 Oct 3.


Comparison of quadriceps strength and handgrip strength in their association with health outcomes in older adults in primary care.

Chan OY, van Houwelingen AH, Gussekloo J, Blom JW, den Elzen WP.

Age (Dordr). 2014;36(5):9714. doi: 10.1007/s11357-014-9714-4. Epub 2014 Oct 4.


Prognostic value of pro-adrenomedullin, procalcitonin and C-reactive protein in predicting outcome of febrile urinary tract infection.

van der Starre WE, Zunder SM, Vollaard AM, van Nieuwkoop C, Stalenhoef JE, Delfos NM, Van't Wout JW, Spelt IC, Blom JW, Leyten EM, Koster T, Ablij HC, van Dissel JT.

Clin Microbiol Infect. 2014 Oct;20(10):1048-54. doi: 10.1111/1469-0691.12645.


What do patients consider to be the most important outcomes for effectiveness studies on migraine treatment? Results of a Delphi study.

Smelt AF, Louter MA, Kies DA, Blom JW, Terwindt GM, van der Heijden GJ, De Gucht V, Ferrari MD, Assendelft WJ.

PLoS One. 2014 Jun 16;9(6):e98933. doi: 10.1371/journal.pone.0098933. eCollection 2014.


Level of satisfaction of older persons with their general practitioner and practice: role of complexity of health problems.

Poot AJ, den Elzen WP, Blom JW, Gussekloo J.

PLoS One. 2014 Apr 7;9(4):e94326. doi: 10.1371/journal.pone.0094326. eCollection 2014.


Triptan use after starting prophylactic migraine treatment: a retrospective cohort study in a primary care population.

Smelt AF, Assendelft WJ, van Dijk CE, Blom JW.

Cephalalgia. 2014 Oct;34(11):927-32. doi: 10.1177/0333102414521511. Epub 2014 Feb 12.


Homocysteine levels and treatment effect in the PROspective Study of Pravastatin in the Elderly at Risk.

Drewes YM, Poortvliet RK, Blom JW, de Ruijter W, Westendorp RG, Stott DJ, Blom HJ, Ford I, Sattar N, Wouter Jukema J, Assendelft WJ, de Craen AJ, Gussekloo J.

J Am Geriatr Soc. 2014 Feb;62(2):213-21. doi: 10.1111/jgs.12660. Epub 2014 Jan 21.


The contribution of immobility risk factors to the incidence of venous thrombosis in an older population.

Engbers MJ, Blom JW, Cushman M, Rosendaal FR, van Hylckama Vlieg A.

J Thromb Haemost. 2014;12(3):290-6. doi: 10.1111/jth.12480.


Diabetes and the course of febrile urinary tract infection.

van der Starre WE, Borgdorff H, Vollaard AM, Delfos NM, van 't Wout JW, Spelt IC, Blom JW, Leyten EM, Koster T, Ablij HC, van Dissel JT, van Nieuwkoop C.

Diabetes Care. 2013 Dec;36(12):e193-4. doi: 10.2337/dc13-0903. No abstract available.


Disability transitions in the oldest old in the general population. The Leiden 85-plus study.

van Houwelingen AH, Cameron ID, Gussekloo J, Putter H, Kurrle S, de Craen AJ, Maier AB, den Elzen WP, Blom JW.

Age (Dordr). 2014 Feb;36(1):483-93. doi: 10.1007/s11357-013-9574-3. Epub 2013 Aug 30.


What is a clinically relevant change on the HIT-6 questionnaire? An estimation in a primary-care population of migraine patients.

Smelt AF, Assendelft WJ, Terwee CB, Ferrari MD, Blom JW.

Cephalalgia. 2014 Jan;34(1):29-36. doi: 10.1177/0333102413497599. Epub 2013 Jul 10.


Predictive value of a profile of routine blood measurements on mortality in older persons in the general population: the Leiden 85-plus Study.

van Houwelingen AH, den Elzen WP, Mooijaart SP, Heijmans M, Blom JW, de Craen AJ, Gussekloo J.

PLoS One. 2013;8(3):e58050. doi: 10.1371/journal.pone.0058050. Epub 2013 Mar 4. Erratum in: PLoS One. 2015;10(6):e0129985.


Low blood pressure predicts increased mortality in very old age even without heart failure: the Leiden 85-plus Study.

Poortvliet RK, Blom JW, de Craen AJ, Mooijaart SP, Westendorp RG, Assendelft WJ, Gussekloo J, de Ruijter W.

Eur J Heart Fail. 2013 May;15(5):528-33. doi: 10.1093/eurjhf/hfs203. Epub 2012 Dec 17.


Blood pressure trends and mortality: the Leiden 85-plus Study.

Poortvliet RK, de Ruijter W, de Craen AJ, Mooijaart SP, Westendorp RG, Assendelft WJ, Gussekloo J, Blom JW.

J Hypertens. 2013 Jan;31(1):63-70. doi: 10.1097/HJH.0b013e32835aa351.


Acceptance of preventive treatment in migraine patients: results of a survey.

Smelt AF, Eijsenga SJ, Assendelft WJ, Blom JW.

Eur J Gen Pract. 2012 Sep;18(3):143-8. doi: 10.3109/13814788.2012.708332.


Proximity to death is associated with frequency of GP contacts in the oldest old: the Leiden 85-plus study.

Blom JW, Lemmens SP, Assendelft WJ, Eekhof JA, Gussekloo J.

Age Ageing. 2012 Nov;41(6):814-7. doi: 10.1093/ageing/afs062. Epub 2012 May 4.


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