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Items: 1 to 50 of 104

1.

Phototherapy and extracorporeal membrane oxygenation facilitate removal of carbon monoxide in rats.

Zazzeron L, Fischbach A, Franco W, Farinelli WA, Ichinose F, Bloch DB, Anderson RR, Zapol WM.

Sci Transl Med. 2019 Oct 9;11(513). pii: eaau4217. doi: 10.1126/scitranslmed.aau4217.

PMID:
31597752
2.

Blood Pressure-Associated Genetic Variants in the Natriuretic Peptide Receptor 1 Gene Modulate Guanylate Cyclase Activity.

Vandenwijngaert S, Ledsky CD, Lahrouchi N, Khan MAF, Wunderer F, Ames L, Honda T, Diener JL, Bezzina CR, Buys ES, Bloch DB, Newton-Cheh C; CHARGE+ Exome Chip Blood Pressure Consortium, the CHD Exome+ Consortium, the Exome BP Consortium, the GoT2D Consortium, the T2D-GENES Consortium and the UK Biobank CardioMetabolic Consortium BP Working Group.

Circ Genom Precis Med. 2019 Aug;12(8):e002472. doi: 10.1161/CIRCGEN.119.002472. Epub 2019 Aug 20.

PMID:
31430210
3.

Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia.

Petersen B, Busch CJ, Schleifer G, Schaack D, Lasitschka F, Bloch KD, Bloch DB, Ichinose F.

Respir Res. 2019 Jun 3;20(1):109. doi: 10.1186/s12931-019-1062-6.

4.

Low guanylyl cyclase activity in Weddell seals: implications for peripheral vasoconstriction and perfusion of the brain during diving.

Hindle AG, Allen KN, Batten AJ, Hückstädt LA, Turner-Maier J, Schulberg SA, Johnson J, Karlsson E, Lindblad-Toh K, Costa DP, Bloch DB, Zapol WM, Buys ES.

Am J Physiol Regul Integr Comp Physiol. 2019 Jun 1;316(6):R704-R715. doi: 10.1152/ajpregu.00283.2018. Epub 2019 Mar 20.

PMID:
30892912
5.

Hepcidin Deficiency Protects Against Atherosclerosis.

Malhotra R, Wunderer F, Barnes HJ, Bagchi A, Buswell MD, O'Rourke CD, Slocum CL, Ledsky CD, Peneyra KM, Sigurslid H, Corman B, Johansson KB, Rhee DK, Bloch KD, Bloch DB.

Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):178-187. doi: 10.1161/ATVBAHA.118.312215.

PMID:
30587002
6.

Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome.

Schleifer G, Marutani E, Ferrari M, Sharma R, Skinner O, Goldberger O, Grange RMH, Peneyra K, Malhotra R, Wepler M, Ichinose F, Bloch DB, Mootha VK, Zapol WM.

Am J Physiol Lung Cell Mol Physiol. 2019 Feb 1;316(2):L391-L399. doi: 10.1152/ajplung.00419.2018. Epub 2018 Dec 6.

7.

Cross-linked hemoglobin bis-tetramers from bioorthogonal coupling do not induce vasoconstriction in the circulation.

Wang A, Singh S, Yu B, Bloch DB, Zapol WM, Kluger R.

Transfusion. 2019 Jan;59(1):359-370. doi: 10.1111/trf.15003. Epub 2018 Nov 15.

PMID:
30444016
8.

Inhaled nitric oxide.

Yu B, Ichinose F, Bloch DB, Zapol WM.

Br J Pharmacol. 2019 Jan;176(2):246-255. doi: 10.1111/bph.14512. Epub 2018 Nov 16. Review.

PMID:
30288739
9.

ALK3 undergoes ligand-independent homodimerization and BMP-induced heterodimerization with ALK2.

Traeger L, Gallitz I, Sekhri R, Bäumer N, Kuhlmann T, Kemming C, Holtkamp M, Müller JC, Karst U, Canonne-Hergaux F, Muckenthaler MU, Bloch DB, Olschewski A, Bartnikas TB, Steinbicker AU.

Free Radic Biol Med. 2018 Dec;129:127-137. doi: 10.1016/j.freeradbiomed.2018.09.021. Epub 2018 Sep 15.

PMID:
30227271
10.

Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites.

Nagasaka Y, Fernandez BO, Steinbicker AU, Spagnolli E, Malhotra R, Bloch DB, Bloch KD, Zapol WM, Feelisch M.

Nitric Oxide. 2018 Nov 1;80:52-60. doi: 10.1016/j.niox.2018.08.006. Epub 2018 Aug 13.

11.

MicroRNA-425 and microRNA-155 cooperatively regulate atrial natriuretic peptide expression and cGMP production.

Vandenwijngaert S, Ledsky CD, Agha O, Wu C, Hu D, Bagchi A, Domian IJ, Buys ES, Newton-Cheh C, Bloch DB.

PLoS One. 2018 Apr 26;13(4):e0196697. doi: 10.1371/journal.pone.0196697. eCollection 2018.

12.

A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells.

Nakagawa A, Ferrari M, Schleifer G, Cooper MK, Liu C, Yu B, Berra L, Klings ES, Safo RS, Chen Q, Musayev FN, Safo MK, Abdulmalik O, Bloch DB, Zapol WM.

Mol Pharm. 2018 May 7;15(5):1954-1963. doi: 10.1021/acs.molpharmaceut.8b00108. Epub 2018 Apr 18.

13.

Development of a portable mini-generator to safely produce nitric oxide for the treatment of infants with pulmonary hypertension.

Yu B, Ferrari M, Schleifer G, Blaesi AH, Wepler M, Zapol WM, Bloch DB.

Nitric Oxide. 2018 May 1;75:70-76. doi: 10.1016/j.niox.2018.02.006. Epub 2018 Feb 24.

14.

Increased Bone Morphogenetic Protein Signaling in the Cutaneous Vasculature of Patients with Calciphylaxis.

Nigwekar SU, Jiramongkolchai P, Wunderer F, Bloch E, Ichinose R, Nazarian RM, Thadhani RI, Malhotra R, Bloch DB.

Am J Nephrol. 2017;46(5):429-438. doi: 10.1159/000484418. Epub 2017 Nov 9.

15.

The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase.

Muenster S, Lieb WS, Fabry G, Allen KN, Kamat SS, Guy AH, Dordea AC, Teixeira L, Tainsh RE, Yu B, Zhu W, Ashpole NE, Malhotra R, Brouckaert P, Bloch DB, Scherrer-Crosbie M, Stamer WD, Kuehn MH, Pasquale LR, Buys ES.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4826-4835. doi: 10.1167/iovs.17-22168.

16.

Detection of Sp110 by Flow Cytometry and Application to Screening Patients for Veno-occlusive Disease with Immunodeficiency.

Marquardsen FA, Baldin F, Wunderer F, Al-Herz W, Mikhael R, Lefranc G, Baz Z, Rezaee F, Hanna R, Kfir-Erenfeld S, Stepensky P, Meyer B, Jauch A, Bigler MB, Burgener AV, Higgins R, Navarini AA, Church JA, Chou J, Geha R, Notarangelo LD, Hess C, Berger CT, Bloch DB, Recher M.

J Clin Immunol. 2017 Oct;37(7):707-714. doi: 10.1007/s10875-017-0431-5. Epub 2017 Aug 21.

17.

Iron Loading Exaggerates the Inflammatory Response to the Toll-like Receptor 4 Ligand Lipopolysaccharide by Altering Mitochondrial Homeostasis.

Hoeft K, Bloch DB, Graw JA, Malhotra R, Ichinose F, Bagchi A.

Anesthesiology. 2017 Jul;127(1):121-135. doi: 10.1097/ALN.0000000000001653.

18.

Endothelial dysfunction inhibits the ability of haptoglobin to prevent hemoglobin-induced hypertension.

Graw JA, Yu B, Rezoagli E, Warren HS, Buys ES, Bloch DB, Zapol WM.

Am J Physiol Heart Circ Physiol. 2017 Jun 1;312(6):H1120-H1127. doi: 10.1152/ajpheart.00851.2016. Epub 2017 Mar 17.

19.

Vitamin K-Dependent Carboxylation of Matrix Gla Protein Influences the Risk of Calciphylaxis.

Nigwekar SU, Bloch DB, Nazarian RM, Vermeer C, Booth SL, Xu D, Thadhani RI, Malhotra R.

J Am Soc Nephrol. 2017 Jun;28(6):1717-1722. doi: 10.1681/ASN.2016060651. Epub 2017 Jan 3.

20.

Pulmonary Phototherapy to Treat Carbon Monoxide Poisoning in Rats.

Zazzeron L, Liu C, Franco W, Nakagawa A, Farinelli WA, Bloch DB, Anderson RR, Zapol WM.

Shock. 2017 Jun;47(6):735-742. doi: 10.1097/SHK.0000000000000797.

21.

Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.

Wang L, Brooks AN, Fan J, Wan Y, Gambe R, Li S, Hergert S, Yin S, Freeman SS, Levin JZ, Fan L, Seiler M, Buonamici S, Smith PG, Chau KF, Cibulskis CL, Zhang W, Rassenti LZ, Ghia EM, Kipps TJ, Fernandes S, Bloch DB, Kotliar D, Landau DA, Shukla SA, Aster JC, Reed R, DeLuca DS, Brown JR, Neuberg D, Getz G, Livak KJ, Meyerson MM, Kharchenko PV, Wu CJ.

Cancer Cell. 2016 Nov 14;30(5):750-763. doi: 10.1016/j.ccell.2016.10.005. Epub 2016 Nov 3.

22.

Soluble epoxide hydrolase deficiency or inhibition enhances murine hypoxic pulmonary vasoconstriction after lipopolysaccharide challenge.

Wepler M, Beloiartsev A, Buswell MD, Panigrahy D, Malhotra R, Buys ES, Radermacher P, Ichinose F, Bloch DB, Zapol WM.

Am J Physiol Lung Cell Mol Physiol. 2016 Dec 1;311(6):L1213-L1221. doi: 10.1152/ajplung.00394.2016. Epub 2016 Nov 4.

23.

Electric Plasma-generated Nitric Oxide: Hemodynamic Effects in Patients with Pulmonary Hypertension.

Berra L, Rodriguez-Lopez J, Rezoagli E, Yu B, Fisher DF, Semigran MJ, Bloch DB, Channick RN, Zapol WM.

Am J Respir Crit Care Med. 2016 Nov 1;194(9):1168-1170. No abstract available.

24.

Detection and removal of impurities in nitric oxide generated from air by pulsed electrical discharge.

Yu B, Blaesi AH, Casey N, Raykhtsaum G, Zazzeron L, Jones R, Morrese A, Dobrynin D, Malhotra R, Bloch DB, Goldstein LE, Zapol WM.

Nitric Oxide. 2016 Nov 30;60:16-23. doi: 10.1016/j.niox.2016.08.005. Epub 2016 Aug 31.

25.

Exposure of Stored Packed Erythrocytes to Nitric Oxide Prevents Transfusion-associated Pulmonary Hypertension.

Muenster S, Beloiartsev A, Yu B, Du E, Abidi S, Dao M, Fabry G, Graw JA, Wepler M, Malhotra R, Fernandez BO, Feelisch M, Bloch KD, Bloch DB, Zapol WM.

Anesthesiology. 2016 Nov;125(5):952-963.

26.

Pulmonary and Systemic Vascular Resistances After Cardiopulmonary Bypass: Role of Hemolysis.

Rezoagli E, Ichinose F, Strelow S, Roy N, Shelton K, Matsumine R, Chen L, Bittner EA, Bloch DB, Zapol WM, Berra L.

J Cardiothorac Vasc Anesth. 2017 Apr;31(2):505-515. doi: 10.1053/j.jvca.2016.06.009. Epub 2016 Jun 8.

PMID:
27590461
27.

Haptoglobin or Hemopexin Therapy Prevents Acute Adverse Effects of Resuscitation After Prolonged Storage of Red Cells.

Graw JA, Mayeur C, Rosales I, Liu Y, Sabbisetti VS, Riley FE, Rechester O, Malhotra R, Warren HS, Colvin RB, Bonventre JV, Bloch DB, Zapol WM.

Circulation. 2016 Sep 27;134(13):945-60. doi: 10.1161/CIRCULATIONAHA.115.019955. Epub 2016 Aug 11.

28.

Decreased Soluble Guanylate Cyclase Contributes to Cardiac Dysfunction Induced by Chronic Doxorubicin Treatment in Mice.

Vandenwijngaert S, Swinnen M, Walravens AS, Beerens M, Gillijns H, Caluwé E, Tainsh RE, Nathan DI, Allen K, Brouckaert P, Bartunek J, Scherrer-Crosbie M, Bloch KD, Bloch DB, Janssens SP, Buys ES.

Antioxid Redox Signal. 2017 Feb 1;26(4):153-164. doi: 10.1089/ars.2015.6542. Epub 2016 Sep 8.

29.

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation.

O'Rourke C, Shelton G, Hutcheson JD, Burke MF, Martyn T, Thayer TE, Shakartzi HR, Buswell MD, Tainsh RE, Yu B, Bagchi A, Rhee DK, Wu C, Derwall M, Buys ES, Yu PB, Bloch KD, Aikawa E, Bloch DB, Malhotra R.

J Vis Exp. 2016 May 31;(111). doi: 10.3791/54017.

30.

Androgen-sensitive hypertension associated with soluble guanylate cyclase-α1 deficiency is mediated by 20-HETE.

Dordea AC, Vandenwijngaert S, Garcia V, Tainsh RE, Nathan DI, Allen K, Raher MJ, Tainsh LT, Zhang F, Lieb WS, Mikelman S, Kirby A, Stevens C, Thoonen R, Hindle AG, Sips PY, Falck JR, Daly MJ, Brouckaert P, Bloch KD, Bloch DB, Malhotra R, Schwartzman ML, Buys ES.

Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1790-800. doi: 10.1152/ajpheart.00877.2015. Epub 2016 May 3.

31.

Novel MicroRNA Regulators of Atrial Natriuretic Peptide Production.

Wu C, Arora P, Agha O, Hurst LA, Allen K, Nathan DI, Hu D, Jiramongkolchai P, Smith JG, Melander O, Trenson S, Janssens SP, Domian I, Wang TJ, Bloch KD, Buys ES, Bloch DB, Newton-Cheh C.

Mol Cell Biol. 2016 Jun 29;36(14):1977-87. doi: 10.1128/MCB.01114-15. Print 2016 Jul 15.

32.

Acute Metabolic Influences on the Natriuretic Peptide System in Humans.

Arora P, Wu C, Hamid T, Arora G, Agha O, Allen K, Tainsh RET, Hu D, Ryan RA, Domian IJ, Buys ES, Bloch DB, Prabhu SD, Bloch KD, Newton-Cheh C, Wang TJ.

J Am Coll Cardiol. 2016 Feb 23;67(7):804-812. doi: 10.1016/j.jacc.2015.11.049.

33.

BMP type I receptor ALK2 is required for angiotensin II-induced cardiac hypertrophy.

Shahid M, Spagnolli E, Ernande L, Thoonen R, Kolodziej SA, Leyton PA, Cheng J, Tainsh RE, Mayeur C, Rhee DK, Wu MX, Scherrer-Crosbie M, Buys ES, Zapol WM, Bloch KD, Bloch DB.

Am J Physiol Heart Circ Physiol. 2016 Apr 15;310(8):H984-94. doi: 10.1152/ajpheart.00879.2015. Epub 2016 Feb 12.

34.

Progesterone receptor membrane component-1 regulates hepcidin biosynthesis.

Li X, Rhee DK, Malhotra R, Mayeur C, Hurst LA, Ager E, Shelton G, Kramer Y, McCulloh D, Keefe D, Bloch KD, Bloch DB, Peterson RT.

J Clin Invest. 2016 Jan;126(1):389-401. doi: 10.1172/JCI83831. Epub 2015 Dec 14.

35.

Targeting BMP signalling in cardiovascular disease and anaemia.

Morrell NW, Bloch DB, ten Dijke P, Goumans MJ, Hata A, Smith J, Yu PB, Bloch KD.

Nat Rev Cardiol. 2016 Feb;13(2):106-20. doi: 10.1038/nrcardio.2015.156. Epub 2015 Oct 13. Review.

36.

S-Nitrosylation of Calcium-Handling Proteins in Cardiac Adrenergic Signaling and Hypertrophy.

Irie T, Sips PY, Kai S, Kida K, Ikeda K, Hirai S, Moazzami K, Jiramongkolchai P, Bloch DB, Doulias PT, Armoundas AA, Kaneki M, Ischiropoulos H, Kranias E, Bloch KD, Stamler JS, Ichinose F.

Circ Res. 2015 Oct 9;117(9):793-803. doi: 10.1161/CIRCRESAHA.115.307157. Epub 2015 Aug 10.

37.

Pulmonary Phototherapy for Treating Carbon Monoxide Poisoning.

Zazzeron L, Liu C, Franco W, Nakagawa A, Farinelli WA, Bloch DB, Anderson RR, Zapol WM.

Am J Respir Crit Care Med. 2015 Nov 15;192(10):1191-9. doi: 10.1164/rccm.201503-0609OC.

38.

Producing nitric oxide by pulsed electrical discharge in air for portable inhalation therapy.

Yu B, Muenster S, Blaesi AH, Bloch DB, Zapol WM.

Sci Transl Med. 2015 Jul 1;7(294):294ra107. doi: 10.1126/scitranslmed.aaa3097.

PMID:
26136478
39.

Inhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency.

Malhotra R, Burke MF, Martyn T, Shakartzi HR, Thayer TE, O'Rourke C, Li P, Derwall M, Spagnolli E, Kolodziej SA, Hoeft K, Mayeur C, Jiramongkolchai P, Kumar R, Buys ES, Yu PB, Bloch KD, Bloch DB.

PLoS One. 2015 Jan 20;10(1):e0117098. doi: 10.1371/journal.pone.0117098. eCollection 2015.

40.

DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells.

Chen HH, Welling M, Bloch DB, Muñoz J, Mientjes E, Chen X, Tramp C, Wu J, Yabuuchi A, Chou YF, Buecker C, Krainer A, Willemsen R, Heck AJ, Geijsen N.

Stem Cell Reports. 2014 Nov 11;3(5):892-904. doi: 10.1016/j.stemcr.2014.09.003. Epub 2014 Oct 11.

41.

Oral administration of a bone morphogenetic protein type I receptor inhibitor prevents the development of anemia of inflammation.

Mayeur C, Kolodziej SA, Wang A, Xu X, Lee A, Yu PB, Shen J, Bloch KD, Bloch DB.

Haematologica. 2015 Feb;100(2):e68-71. doi: 10.3324/haematol.2014.111484. Epub 2014 Oct 17. No abstract available.

42.

Anti-kelch-like 12 and anti-hexokinase 1: novel autoantibodies in primary biliary cirrhosis.

Norman GL, Yang CY, Ostendorff HP, Shums Z, Lim MJ, Wang J, Awad A, Hirschfield GM, Milkiewicz P, Bloch DB, Rothschild KJ, Bowlus CL, Adamopoulos IE, Leung PS, Janssen HJ, Cheung AC, Coltescu C, Gershwin ME.

Liver Int. 2015 Feb;35(2):642-51. doi: 10.1111/liv.12690. Epub 2014 Oct 10.

43.

Reply: To PMID 24431286.

Khosroshahi A, Cheryk LA, Bloch DB, Stone JH.

Arthritis Rheumatol. 2014 Nov;66(11):3247-8. doi: 10.1002/art.38751. No abstract available.

44.

LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression.

Bloch DB, Li P, Bloch EG, Berenson DF, Galdos RL, Arora P, Malhotra R, Wu C, Yang W.

PLoS One. 2014 Apr 22;9(4):e94784. doi: 10.1371/journal.pone.0094784. eCollection 2014.

45.

The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6.

Mayeur C, Lohmeyer LK, Leyton P, Kao SM, Pappas AE, Kolodziej SA, Spagnolli E, Yu B, Galdos RL, Yu PB, Peterson RT, Bloch DB, Bloch KD, Steinbicker AU.

Blood. 2014 Apr 3;123(14):2261-8. doi: 10.1182/blood-2013-02-480095. Epub 2014 Feb 5.

46.

Brief Report: spuriously low serum IgG4 concentrations caused by the prozone phenomenon in patients with IgG4-related disease.

Khosroshahi A, Cheryk LA, Carruthers MN, Edwards JA, Bloch DB, Stone JH.

Arthritis Rheumatol. 2014 Jan;66(1):213-7. doi: 10.1002/art.38193.

47.

International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies.

Agmon-Levin N, Damoiseaux J, Kallenberg C, Sack U, Witte T, Herold M, Bossuyt X, Musset L, Cervera R, Plaza-Lopez A, Dias C, Sousa MJ, Radice A, Eriksson C, Hultgren O, Viander M, Khamashta M, Regenass S, Andrade LE, Wiik A, Tincani A, Rönnelid J, Bloch DB, Fritzler MJ, Chan EK, Garcia-De La Torre I, Konstantinov KN, Lahita R, Wilson M, Vainio O, Fabien N, Sinico RA, Meroni P, Shoenfeld Y.

Ann Rheum Dis. 2014 Jan;73(1):17-23. doi: 10.1136/annrheumdis-2013-203863. Epub 2013 Oct 14.

48.

Deletion of the sequence encoding the tail domain of the bone morphogenetic protein type 2 receptor reveals a bone morphogenetic protein 7-specific gain of function.

Leyton PA, Beppu H, Pappas A, Martyn TM, Derwall M, Baron DM, Galdos R, Bloch DB, Bloch KD.

PLoS One. 2013 Oct 8;8(10):e76947. doi: 10.1371/journal.pone.0076947. eCollection 2013.

49.

Atrial natriuretic peptide is negatively regulated by microRNA-425.

Arora P, Wu C, Khan AM, Bloch DB, Davis-Dusenbery BN, Ghorbani A, Spagnolli E, Martinez A, Ryan A, Tainsh LT, Kim S, Rong J, Huan T, Freedman JE, Levy D, Miller KK, Hata A, Del Monte F, Vandenwijngaert S, Swinnen M, Janssens S, Holmes TM, Buys ES, Bloch KD, Newton-Cheh C, Wang TJ.

J Clin Invest. 2013 Aug;123(8):3378-82. doi: 10.1172/JCI67383. Epub 2013 Jul 15.

50.

Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury.

Masuzawa A, Black KM, Pacak CA, Ericsson M, Barnett RJ, Drumm C, Seth P, Bloch DB, Levitsky S, Cowan DB, McCully JD.

Am J Physiol Heart Circ Physiol. 2013 Apr 1;304(7):H966-82. doi: 10.1152/ajpheart.00883.2012. Epub 2013 Jan 25.

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