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Items: 1 to 50 of 63

1.

Molecular genetic and biochemical characterization of a putative family of zinc metalloproteins in Caenorhabditis elegans.

Chaudhuri P, Imam HT, Essig Y, Krasauskas J, Webb SM, Blindauer CA, Stürzenbaum SR.

Metallomics. 2018 Dec 12;10(12):1814-1823. doi: 10.1039/c8mt00169c.

2.

Crosstalk between zinc and free fatty acids in plasma.

Coverdale JPC, Khazaipoul S, Arya S, Stewart AJ, Blindauer CA.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Apr;1864(4):532-542. doi: 10.1016/j.bbalip.2018.09.007. Epub 2018 Sep 25. Review.

3.

The type 4 metallothionein from Brassica napus seeds folds in a metal-dependent fashion and favours zinc over other metals.

Mierek-Adamska A, Dąbrowska GB, Blindauer CA.

Metallomics. 2018 Oct 17;10(10):1430-1443. doi: 10.1039/c8mt00161h.

PMID:
30176031
4.

Ischemia-modified albumin: Crosstalk between fatty acid and cobalt binding.

Coverdale JPC, Katundu KGH, Sobczak AIS, Arya S, Blindauer CA, Stewart AJ.

Prostaglandins Leukot Essent Fatty Acids. 2018 Aug;135:147-157. doi: 10.1016/j.plefa.2018.07.014. Epub 2018 Jul 20. Review.

5.

Bacterial zinc uptake regulator proteins and their regulons.

Mikhaylina A, Ksibe AZ, Scanlan DJ, Blindauer CA.

Biochem Soc Trans. 2018 Aug 20;46(4):983-1001. doi: 10.1042/BST20170228. Epub 2018 Jul 31. Review.

6.

Native electrospray mass spectrometry approaches to probe the interaction between zinc and an anti-angiogenic peptide from histidine-rich glycoprotein.

Martin EM, Kondrat FDL, Stewart AJ, Scrivens JH, Sadler PJ, Blindauer CA.

Sci Rep. 2018 Jun 5;8(1):8646. doi: 10.1038/s41598-018-26924-1.

7.

Differential reactivity of closely related zinc(II)-binding metallothioneins from the plant Arabidopsis thaliana.

Imam HT, Blindauer CA.

J Biol Inorg Chem. 2018 Jan;23(1):137-154. doi: 10.1007/s00775-017-1516-6. Epub 2017 Dec 7.

8.

The potent anti-cancer activity of Dioclea lasiocarpa lectin.

Gondim ACS, Romero-Canelón I, Sousa EHS, Blindauer CA, Butler JS, Romero MJ, Sanchez-Cano C, Sousa BL, Chaves RP, Nagano CS, Cavada BS, Sadler PJ.

J Inorg Biochem. 2017 Oct;175:179-189. doi: 10.1016/j.jinorgbio.2017.07.011. Epub 2017 Jul 16.

9.

Metallothionein from Wild Populations of the African Catfish Clarias gariepinus: From Sequence, Protein Expression and Metal Binding Properties to Transcriptional Biomarker of Metal Pollution.

M'kandawire E, Mierek-Adamska A, Stürzenbaum SR, Choongo K, Yabe J, Mwase M, Saasa N, Blindauer CA.

Int J Mol Sci. 2017 Jul 18;18(7). pii: E1548. doi: 10.3390/ijms18071548.

10.

Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins.

Handing KB, Shabalin IG, Kassaar O, Khazaipoul S, Blindauer CA, Stewart AJ, Chruszcz M, Minor W.

Chem Sci. 2016 Nov 1;7(11):6635-6648. doi: 10.1039/c6sc02267g. Epub 2016 Aug 15.

11.

Sediment Metal Contamination in the Kafue River of Zambia and Ecological Risk Assessment.

M'kandawire E, Choongo K, Yabe J, Mwase M, Saasa N, Nakayama SMM, Bortey-Sam N, Blindauer CA.

Bull Environ Contam Toxicol. 2017 Jul;99(1):108-116. doi: 10.1007/s00128-017-2089-3. Epub 2017 Apr 22.

PMID:
28434067
12.

O2 -independent demethylation of trimethylamine N-oxide by Tdm of Methylocella silvestris.

Zhu Y, Ksibe AZ, Schäfer H, Blindauer CA, Bugg TD, Chen Y.

FEBS J. 2016 Nov;283(21):3979-3993. doi: 10.1111/febs.13902. Epub 2016 Oct 20.

13.

Stability Enhancing N-Terminal PEGylation of Oxytocin Exploiting Different Polymer Architectures and Conjugation Approaches.

Collins J, Kempe K, Wilson P, Blindauer CA, McIntosh MP, Davis TP, Whittaker MR, Haddleton DM.

Biomacromolecules. 2016 Aug 8;17(8):2755-66. doi: 10.1021/acs.biomac.6b00919. Epub 2016 Jul 15.

14.

Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase.

Usha V, Lloyd AJ, Roper DI, Dowson CG, Kozlov G, Gehring K, Chauhan S, Imam HT, Blindauer CA, Besra GS.

Sci Rep. 2016 Mar 15;6:23191. doi: 10.1038/srep23191.

15.

Fatty Acid-Mediated Inhibition of Metal Binding to the Multi-Metal Site on Serum Albumin: Implications for Cardiovascular Disease.

Blindauer CA, Khazaipoul S, Yu R, Stewart AJ.

Curr Top Med Chem. 2016;16(27):3021-3032. Review.

PMID:
26881707
16.

Unexpected Interactions of the Cyanobacterial Metallothionein SmtA with Uranium.

Acharya C, Blindauer CA.

Inorg Chem. 2016 Feb 15;55(4):1505-15. doi: 10.1021/acs.inorgchem.5b02327. Epub 2016 Jan 25.

PMID:
26808269
17.

Earthworm Lumbricus rubellus MT-2: Metal Binding and Protein Folding of a True Cadmium-MT.

Kowald GR, Stürzenbaum SR, Blindauer CA.

Int J Mol Sci. 2016 Jan 5;17(1). pii: E65. doi: 10.3390/ijms17010065.

18.

Prion infection in cells is abolished by a mutated manganese transporter but shows no relation to zinc.

Pass R, Frudd K, Barnett JP, Blindauer CA, Brown DR.

Mol Cell Neurosci. 2015 Sep;68:186-93. doi: 10.1016/j.mcn.2015.08.004. Epub 2015 Aug 5.

PMID:
26253862
19.

The reduced Co(2+) -binding ability of ischaemia-modified albumin is unlikely to be because of oxidative modification of the N-terminus.

Stewart AJ, Blindauer CA.

Liver Int. 2015 Dec;35(12):2622-3. doi: 10.1111/liv.12873. Epub 2015 Jun 3. No abstract available.

PMID:
25998319
20.

Characterization of folding cores in the cyclophilin A-cyclosporin A complex.

Heal JW, Wells SA, Blindauer CA, Freedman RB, Römer RA.

Biophys J. 2015 Apr 7;108(7):1739-1746. doi: 10.1016/j.bpj.2015.02.017.

21.

Advances in the molecular understanding of biological zinc transport.

Blindauer CA.

Chem Commun (Camb). 2015 Mar 18;51(22):4544-63. doi: 10.1039/c4cc10174j.

PMID:
25627157
22.

Plasma free fatty acid levels influence Zn(2+) -dependent histidine-rich glycoprotein-heparin interactions via an allosteric switch on serum albumin.

Kassaar O, Schwarz-Linek U, Blindauer CA, Stewart AJ.

J Thromb Haemost. 2015 Jan;13(1):101-10. doi: 10.1111/jth.12771. Epub 2014 Nov 22.

23.

Identification of major zinc-binding proteins from a marine cyanobacterium: insight into metal uptake in oligotrophic environments.

Barnett JP, Scanlan DJ, Blindauer CA.

Metallomics. 2014 Jul;6(7):1254-68. doi: 10.1039/c4mt00048j.

PMID:
24870224
24.

Protein disulfide-isomerase interacts with a substrate protein at all stages along its folding pathway.

Irvine AG, Wallis AK, Sanghera N, Rowe ML, Ruddock LW, Howard MJ, Williamson RA, Blindauer CA, Freedman RB.

PLoS One. 2014 Jan 20;9(1):e82511. doi: 10.1371/journal.pone.0082511. eCollection 2014.

25.

A canonical EF-loop directs Ca(2+) -sensitivity in phospholipase C-η2.

Popovics P, Lu J, Nadia Kamil L, Morgan K, Millar RP, Schmid R, Blindauer CA, Stewart AJ.

J Cell Biochem. 2014 Mar;115(3):557-65. doi: 10.1002/jcb.24690.

PMID:
24123053
26.

Allosteric modulation of zinc speciation by fatty acids.

Barnett JP, Blindauer CA, Kassaar O, Khazaipoul S, Martin EM, Sadler PJ, Stewart AJ.

Biochim Biophys Acta. 2013 Dec;1830(12):5456-64. doi: 10.1016/j.bbagen.2013.05.028. Epub 2013 May 29. Review.

27.

Diversity and distribution of plant metallothioneins: a review of structure, properties and functions.

Leszczyszyn OI, Imam HT, Blindauer CA.

Metallomics. 2013 Sep;5(9):1146-69. doi: 10.1039/c3mt00072a. Review.

PMID:
23694960
28.

Lessons on the critical interplay between zinc binding and protein structure and dynamics.

Blindauer CA.

J Inorg Biochem. 2013 Apr;121:145-55. doi: 10.1016/j.jinorgbio.2013.01.005. Epub 2013 Jan 14. Review. Erratum in: J Inorg Biochem. 2013 Jun;123:88.

PMID:
23376625
29.

Resolution of a paradox by native mass spectrometry: facile occupation of all four metal binding sites in the dimeric zinc sensor SmtB.

Kondrat FD, Kowald GR, Scarff CA, Scrivens JH, Blindauer CA.

Chem Commun (Camb). 2013 Jan 28;49(8):813-5. doi: 10.1039/c2cc38387j.

PMID:
23235389
31.

Allosteric inhibition of cobalt binding to albumin by fatty acids: implications for the detection of myocardial ischemia.

Lu J, Stewart AJ, Sadler PJ, Pinheiro TJ, Blindauer CA.

J Med Chem. 2012 May 10;55(9):4425-30. doi: 10.1021/jm3003137. Epub 2012 May 2.

PMID:
22519414
32.

Mining genomes of marine cyanobacteria for elements of zinc homeostasis.

Barnett JP, Millard A, Ksibe AZ, Scanlan DJ, Schmid R, Blindauer CA.

Front Microbiol. 2012 Apr 11;3:142. doi: 10.3389/fmicb.2012.00142. eCollection 2012.

33.

Direct peptide bioconjugation/PEGylation at tyrosine with linear and branched polymeric diazonium salts.

Jones MW, Mantovani G, Blindauer CA, Ryan SM, Wang X, Brayden DJ, Haddleton DM.

J Am Chem Soc. 2012 May 2;134(17):7406-13. doi: 10.1021/ja211855q. Epub 2012 Apr 21.

PMID:
22494012
34.

Protein fractionation and detection for metalloproteomics: challenges and approaches.

Barnett JP, Scanlan DJ, Blindauer CA.

Anal Bioanal Chem. 2012 Apr;402(10):3311-22. doi: 10.1007/s00216-012-5743-y. Review.

PMID:
22302168
35.

Fractionation and identification of metalloproteins from a marine cyanobacterium.

Barnett JP, Scanlan DJ, Blindauer CA.

Anal Bioanal Chem. 2012 Apr;402(10):3371-7. doi: 10.1007/s00216-011-5708-6. Epub 2012 Jan 19.

PMID:
22258207
36.

A molecular mechanism for modulating plasma Zn speciation by fatty acids.

Lu J, Stewart AJ, Sleep D, Sadler PJ, Pinheiro TJ, Blindauer CA.

J Am Chem Soc. 2012 Jan 25;134(3):1454-7. doi: 10.1021/ja210496n. Epub 2012 Jan 12.

37.

The Tat protein export pathway and its role in cyanobacterial metalloprotein biosynthesis.

Barnett JP, Robinson C, Scanlan DJ, Blindauer CA.

FEMS Microbiol Lett. 2011 Dec;325(1):1-9. doi: 10.1111/j.1574-6968.2011.02391.x. Epub 2011 Sep 20. Review.

38.

C. elegans metallothioneins: response to and defence against ROS toxicity.

Zeitoun-Ghandour S, Leszczyszyn OI, Blindauer CA, Geier FM, Bundy JG, Stürzenbaum SR.

Mol Biosyst. 2011 Aug;7(8):2397-406. doi: 10.1039/c1mb05114h. Epub 2011 Jun 7.

PMID:
21647514
39.

Bacterial metallothioneins: past, present, and questions for the future.

Blindauer CA.

J Biol Inorg Chem. 2011 Oct;16(7):1011-24. doi: 10.1007/s00775-011-0790-y. Epub 2011 May 19. Review.

PMID:
21594652
40.

Cytosolic metal handling in plants: determinants for zinc specificity in metal transporters and metallothioneins.

Blindauer CA, Schmid R.

Metallomics. 2010 Aug;2(8):510-29. doi: 10.1039/c004880a. Epub 2010 Jul 7.

PMID:
21072336
41.

Tools for metal ion sorting: in vitro evidence for partitioning of zinc and cadmium in C. elegans metallothionein isoforms.

Leszczyszyn OI, Zeitoun-Ghandour S, Stürzenbaum SR, Blindauer CA.

Chem Commun (Camb). 2011 Jan 7;47(1):448-50. doi: 10.1039/c0cc02188a. Epub 2010 Sep 28.

PMID:
20877848
42.

Zinc transfer from the embryo-specific metallothionein E(C) from wheat: a case study.

Leszczyszyn OI, Blindauer CA.

Phys Chem Chem Phys. 2010 Nov 7;12(41):13408-18. doi: 10.1039/c0cp00680g. Epub 2010 Sep 27.

PMID:
20877787
43.

The two Caenorhabditis elegans metallothioneins (CeMT-1 and CeMT-2) discriminate between essential zinc and toxic cadmium.

Zeitoun-Ghandour S, Charnock JM, Hodson ME, Leszczyszyn OI, Blindauer CA, Stürzenbaum SR.

FEBS J. 2010 Jun;277(11):2531-42. doi: 10.1111/j.1742-4658.2010.07667.x.

44.

The isolated Cys2His2 site in EC metallothionein mediates metal-specific protein folding.

Leszczyszyn OI, White CR, Blindauer CA.

Mol Biosyst. 2010 Sep;6(9):1592-603. doi: 10.1039/c002348e.

PMID:
20467686
45.

Metallothioneins: unparalleled diversity in structures and functions for metal ion homeostasis and more.

Blindauer CA, Leszczyszyn OI.

Nat Prod Rep. 2010 May;27(5):720-41. doi: 10.1039/b906685n. Epub 2010 Mar 25. Review.

PMID:
20442962
46.

Plasma fatty acid levels may regulate the Zn(2+)-dependent activities of histidine-rich glycoprotein.

Stewart AJ, Blindauer CA, Sadler PJ.

Biochimie. 2009 Nov-Dec;91(11-12):1518-22. doi: 10.1016/j.biochi.2009.08.002. Epub 2009 Aug 11.

PMID:
19679159
47.

Structure, properties, and engineering of the major zinc binding site on human albumin.

Blindauer CA, Harvey I, Bunyan KE, Stewart AJ, Sleep D, Harrison DJ, Berezenko S, Sadler PJ.

J Biol Chem. 2009 Aug 21;284(34):23116-24. doi: 10.1074/jbc.M109.003459. Epub 2009 Jun 11.

48.

Albumin as a zinc carrier: properties of its high-affinity zinc-binding site.

Lu J, Stewart AJ, Sadler PJ, Pinheiro TJ, Blindauer CA.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1317-21. doi: 10.1042/BST0361317. Review.

PMID:
19021548
49.

Zinc-handling in cyanobacteria: an update.

Blindauer CA.

Chem Biodivers. 2008 Oct;5(10):1990-2013. doi: 10.1002/cbdv.200890183. Review.

PMID:
18972521
50.

Metallothioneins with unusual residues: histidines as modulators of zinc affinity and reactivity.

Blindauer CA.

J Inorg Biochem. 2008 Mar;102(3):507-21. doi: 10.1016/j.jinorgbio.2007.10.032. Epub 2007 Nov 28.

PMID:
18171588

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