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Switching medication products during the treatment of psychiatric illness.

Blier P, Margolese HC, Wilson EA, Boucher M.

Int J Psychiatry Clin Pract. 2019 Feb 8:1-12. doi: 10.1080/13651501.2018.1508724. [Epub ahead of print]


Leveraging Machine Learning Approaches for Predicting Antidepressant Treatment Response Using Electroencephalography (EEG) and Clinical Data.

Jaworska N, de la Salle S, Ibrahim MH, Blier P, Knott V.

Front Psychiatry. 2019 Jan 14;9:768. doi: 10.3389/fpsyt.2018.00768. eCollection 2018.


Optimized regimens of combined medications for the treatment of major depressive disorder: a double-blind, randomized-controlled trial.

Zuilhof Z, Norris S, Blondeau C, Tessier P, Blier P.

Neuropsychiatr Dis Treat. 2018 Nov 22;14:3209-3218. doi: 10.2147/NDT.S175203. eCollection 2018.


Energy metabolism and survival of the juvenile recruits of the American lobster (Homarus americanus) exposed to a gradient of elevated seawater pCO2.

Menu-Courey K, Noisette F, Piedalue S, Daoud D, Blair T, Blier PU, Azetsu-Scott K, Calosi P.

Mar Environ Res. 2019 Jan;143:111-123. doi: 10.1016/j.marenvres.2018.10.002. Epub 2018 Oct 9.


Synergistic effect of aripiprazole and escitalopram in increasing serotonin but not norepinephrine neurotransmission in the rat hippocampus.

Ebrahimzadeh M, El Mansari M, Blier P.

Neuropharmacology. 2019 Mar 1;146:12-18. doi: 10.1016/j.neuropharm.2018.11.006. Epub 2018 Nov 8.


Hybridization between char species (Salvelinus alpinus and Salvelinus fontinalis): a fast track for novel allometric trajectories.

Dupont Cyr BA, Dufresne F, Christen F, Desrosiers V, Proulx É, Le François NR, Vandenberg GW, Blier PU.

Biol Open. 2018 Oct 19;7(10). pii: bio033332. doi: 10.1242/bio.033332.


Involvement of 5-HT1A and 5-HT2A Receptors but Not α 2-Adrenoceptors in the Acute Electrophysiological Effects of Cariprazine in the Rat Brain In Vivo.

Herman A, El Mansari M, Adham N, Kiss B, Farkas B, Blier P.

Mol Pharmacol. 2018 Dec;94(6):1363-1370. doi: 10.1124/mol.118.113290. Epub 2018 Oct 15. Erratum in: Mol Pharmacol. 2019 Feb;95(2):235.


Large muscles are beneficial but not required for improving thermogenic capacity in small birds.

Milbergue MS, Blier PU, Vézina F.

Sci Rep. 2018 Sep 18;8(1):14009. doi: 10.1038/s41598-018-32041-w.


Effects of fasting and refeeding on protein and glucose metabolism in Arctic charr.

Cassidy AA, Blier PU, Le François NR, Dionne P, Morin PJ, Lamarre SG.

Comp Biochem Physiol A Mol Integr Physiol. 2018 Dec;226:66-74. doi: 10.1016/j.cbpa.2018.08.010. Epub 2018 Aug 23.


Mitochondrial phenotype during torpor: Modulation of mitochondrial electron transport system in the Chilean mouse-opossum Thylamys elegans.

Cortes PA, Bozinovic F, Blier PU.

Comp Biochem Physiol A Mol Integr Physiol. 2018 Jul;221:7-14. doi: 10.1016/j.cbpa.2017.12.014. Epub 2018 Mar 15.


Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production.

Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU.

Free Radic Biol Med. 2018 Feb 20;116:11-18. doi: 10.1016/j.freeradbiomed.2017.12.037. Epub 2017 Dec 30.


The comparative effectiveness of electroencephalographic indices in predicting response to escitalopram therapy in depression: A pilot study.

Baskaran A, Farzan F, Milev R, Brenner CA, Alturi S, Pat McAndrews M, Blier P, Evans K, Foster JA, Frey BN, Giacobbe P, Lam RW, Leri F, MacQueen GM, Müller DJ, Parikh SV, Rotzinger S, Soares CN, Strother SC, Turecki G, Kennedy SH; CAN-BIND Investigators Team.

J Affect Disord. 2018 Feb;227:542-549. doi: 10.1016/j.jad.2017.10.028. Epub 2017 Nov 3.


Pre-treatment EEG signal variability is associated with treatment success in depression.

Jaworska N, Wang H, Smith DM, Blier P, Knott V, Protzner AB.

Neuroimage Clin. 2017 Oct 31;17:368-377. doi: 10.1016/j.nicl.2017.10.035. eCollection 2018.


Partial inhibition of catecholamine activity and enhanced responsiveness to NMDA after sustained administration of vortioxetine.

Ebrahimzadeh M, El Mansari M, Blier P.

Neuropharmacology. 2018 Jan;128:425-432. doi: 10.1016/j.neuropharm.2017.10.036. Epub 2017 Nov 13.


Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex.

Kake-Guena SA, Touisse K, Warren BE, Scott KY, Dufresne F, Blier PU, Lemieux H.

J Therm Biol. 2017 Oct;69:23-31. doi: 10.1016/j.jtherbio.2017.05.005. Epub 2017 May 22.


Functional Recovery in Major Depressive Disorder: Providing Early Optimal Treatment for the Individual Patient.

Oluboka OJ, Katzman MA, Habert J, McIntosh D, MacQueen GM, Milev RV, McIntyre RS, Blier P.

Int J Neuropsychopharmacol. 2018 Feb 1;21(2):128-144. doi: 10.1093/ijnp/pyx081.


Potential Application of Eicosapentaenoic Acid Monoacylglyceride in the Management of Colorectal Cancer.

Morin C, Rodríguez E, Blier PU, Fortin S.

Mar Drugs. 2017 Sep 4;15(9). pii: E283. doi: 10.3390/md15090283.


What modulates animal longevity? Fast and slow aging in bivalves as a model for the study of lifespan.

Blier PU, Abele D, Munro D, Degletagne C, Rodriguez E, Hagen T.

Semin Cell Dev Biol. 2017 Oct;70:130-140. doi: 10.1016/j.semcdb.2017.07.046. Epub 2017 Aug 1. Review.


MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.

Lopez JP, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C, Han MH, Foster J, Frey BN, Soares CN, Müller DJ, Farzan F, Leri F, MacQueen GM, Feilotter H, Tyryshkin K, Evans KR, Giacobbe P, Blier P, Lam RW, Milev R, Parikh SV, Rotzinger S, Strother SC, Lewis CM, Aitchison KJ, Wittenberg GM, Mechawar N, Nestler EJ, Uher R, Kennedy SH, Turecki G.

Nat Commun. 2017 May 22;8:15497. doi: 10.1038/ncomms15497.


Eicosapentaenoic acid monoglyceride resolves inflammation in an ex vivo model of human peripheral blood mononuclear cell.

Morin C, Charbonneau L, Ouellet N, Ouellet H, Blier PU, Dufresne F, Fortin S.

Eur J Pharmacol. 2017 Jul 15;807:205-211. doi: 10.1016/j.ejphar.2017.05.018. Epub 2017 May 10.


Evolved genetic and phenotypic differences due to mitochondrial-nuclear interactions.

Baris TZ, Wagner DN, Dayan DI, Du X, Blier PU, Pichaud N, Oleksiak MF, Crawford DL.

PLoS Genet. 2017 Mar 31;13(3):e1006517. doi: 10.1371/journal.pgen.1006517. eCollection 2017 Mar.


Progress on the Neuroscience-Based Nomenclature (NbN) for Psychotropic Medications.

Blier P, Oquendo MA, Kupfer DJ.

Neuropsychopharmacology. 2017 Sep;42(10):1927-1928. doi: 10.1038/npp.2017.33. Epub 2017 Feb 9. No abstract available.


Effects of levomilnacipran ER on noradrenergic symptoms, anxiety symptoms, and functional impairment in adults with major depressive disorder: Post hoc analysis of 5 clinical trials.

Blier P, Gommoll C, Chen C, Kramer K.

J Affect Disord. 2017 Mar 1;210:273-279. doi: 10.1016/j.jad.2016.11.011. Epub 2016 Nov 15.


Juvenile Fibromyalgia: A Primary Pain, or Pain Processing, Disorder.

Zemel L, Blier PR.

Semin Pediatr Neurol. 2016 Aug;23(3):231-241. doi: 10.1016/j.spen.2016.10.007. Epub 2016 Oct 14. Review.


Inverse agonists - What do they mean for psychiatry?

Nutt D, Stahl S, Blier P, Drago F, Zohar J, Wilson S.

Eur Neuropsychopharmacol. 2017 Jan;27(1):87-90. doi: 10.1016/j.euroneuro.2016.11.013. Epub 2016 Dec 7.


The International College of Neuro-Psychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 3: The Clinical Guidelines.

Fountoulakis KN, Grunze H, Vieta E, Young A, Yatham L, Blier P, Kasper S, Moeller HJ.

Int J Neuropsychopharmacol. 2017 Feb 1;20(2):180-195. doi: 10.1093/ijnp/pyw109. Review.


Can multi-generational exposure to ocean warming and acidification lead to the adaptation of life history and physiology in a marine metazoan?

Gibbin EM, Chakravarti LJ, Jarrold MD, Christen F, Turpin V, Massamba N'Siala G, Blier PU, Calosi P.

J Exp Biol. 2017 Feb 15;220(Pt 4):551-563. doi: 10.1242/jeb.149989. Epub 2016 Nov 30.


Thermal sensitivity and phenotypic plasticity of cardiac mitochondrial metabolism in European perch, Perca fluviatilis.

Ekström A, Sandblom E, Blier PU, Dupont Cyr BA, Brijs J, Pichaud N.

J Exp Biol. 2017 Feb 1;220(Pt 3):386-396. doi: 10.1242/jeb.150698. Epub 2016 Nov 16.


The International College of Neuro-Psychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 2: Review, Grading of the Evidence, and a Precise Algorithm.

Fountoulakis KN, Yatham L, Grunze H, Vieta E, Young A, Blier P, Kasper S, Moeller HJ.

Int J Neuropsychopharmacol. 2017 Feb 1;20(2):121-179. doi: 10.1093/ijnp/pyw100. Review.


The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines.

Fountoulakis KN, Young A, Yatham L, Grunze H, Vieta E, Blier P, Moeller HJ, Kasper S.

Int J Neuropsychopharmacol. 2017 Feb 1;20(2):98-120. doi: 10.1093/ijnp/pyw091. Review.


Can trans-generational experiments be used to enhance species resilience to ocean warming and acidification?

Chakravarti LJ, Jarrold MD, Gibbin EM, Christen F, Massamba-N'Siala G, Blier PU, Calosi P.

Evol Appl. 2016 Jul 6;9(9):1133-1146. eCollection 2016 Oct.


The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 4: Unmet Needs in the Treatment of Bipolar Disorder and Recommendations for Future Research.

Fountoulakis KN, Vieta E, Young A, Yatham L, Grunze H, Blier P, Moeller HJ, Kasper S.

Int J Neuropsychopharmacol. 2017 Feb 1;20(2):196-205. doi: 10.1093/ijnp/pyw072. Review.


A Neuroscience-Based Nomenclature (NbN) for Psychotropic Agents.

Frazer A, Blier P.

Int J Neuropsychopharmacol. 2016 Aug 12;19(8). pii: pyw066. doi: 10.1093/ijnp/pyw066. Print 2016 Aug. No abstract available.


Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 3. Pharmacological Treatments.

Kennedy SH, Lam RW, McIntyre RS, Tourjman SV, Bhat V, Blier P, Hasnain M, Jollant F, Levitt AJ, MacQueen GM, McInerney SJ, McIntosh D, Milev RV, Müller DJ, Parikh SV, Pearson NL, Ravindran AV, Uher R; CANMAT Depression Work Group.

Can J Psychiatry. 2016 Sep;61(9):540-60. doi: 10.1177/0706743716659417. Epub 2016 Aug 2. Review. Erratum in: Can J Psychiatry. 2017 May;62(5):356.


Gene by environmental interactions affecting oxidative phosphorylation and thermal sensitivity.

Baris TZ, Blier PU, Pichaud N, Crawford DL, Oleksiak MF.

Am J Physiol Regul Integr Comp Physiol. 2016 Jul 1;311(1):R157-65. doi: 10.1152/ajpregu.00008.2016. Epub 2016 May 25.


Neuroscience-based Nomenclature (NbN) for Journal of Psychopharmacology.

Nutt DJ, Blier P.

J Psychopharmacol. 2016 May;30(5):413-5. doi: 10.1177/0269881116642903. No abstract available.


Altered monoamine system activities after prenatal and adult stress: A role for stress resilience?

Oosterhof CA, El Mansari M, Merali Z, Blier P.

Brain Res. 2016 Jul 1;1642:409-418. doi: 10.1016/j.brainres.2016.04.032. Epub 2016 Apr 14.


Discovering biomarkers for antidepressant response: protocol from the Canadian biomarker integration network in depression (CAN-BIND) and clinical characteristics of the first patient cohort.

Lam RW, Milev R, Rotzinger S, Andreazza AC, Blier P, Brenner C, Daskalakis ZJ, Dharsee M, Downar J, Evans KR, Farzan F, Foster JA, Frey BN, Geraci J, Giacobbe P, Feilotter HE, Hall GB, Harkness KL, Hassel S, Ismail Z, Leri F, Liotti M, MacQueen GM, McAndrews MP, Minuzzi L, Müller DJ, Parikh SV, Placenza FM, Quilty LC, Ravindran AV, Salomons TV, Soares CN, Strother SC, Turecki G, Vaccarino AL, Vila-Rodriguez F, Kennedy SH; CAN-BIND Investigator Team.

BMC Psychiatry. 2016 Apr 16;16:105. doi: 10.1186/s12888-016-0785-x.


Neurobiology of depression and mechanism of action of depression treatments.

Blier P.

J Clin Psychiatry. 2016 Mar;77(3):e319. doi: 10.4088/JCP.13097tx3c.


The noradrenergic paradox: implications in the management of depression and anxiety.

Montoya A, Bruins R, Katzman MA, Blier P.

Neuropsychiatr Dis Treat. 2016 Mar 1;12:541-57. doi: 10.2147/NDT.S91311. eCollection 2016. Review.


MAG-EPA reduces severity of DSS-induced colitis in rats.

Morin C, Blier PU, Fortin S.

Am J Physiol Gastrointest Liver Physiol. 2016 May 15;310(10):G808-21. doi: 10.1152/ajpgi.00136.2015. Epub 2016 Mar 24.


Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies.

Wolff JN, Pichaud N, Camus MF, Côté G, Blier PU, Dowling DK.

J Evol Biol. 2016 Apr;29(4):736-47. doi: 10.1111/jeb.12822. Epub 2016 Jan 20.


Data mining EEG signals in depression for their diagnostic value.

Mohammadi M, Al-Azab F, Raahemi B, Richards G, Jaworska N, Smith D, de la Salle S, Blier P, Knott V.

BMC Med Inform Decis Mak. 2015 Dec 23;15:108. doi: 10.1186/s12911-015-0227-6.


Mitochondrial phenotype of marsupial torpor: Fuel metabolic switch in the Chilean mouse-opossum Thylamys elegans.

Cortés PA, Bacigalupe LD, Mondaca F, Desrosiers V, Blier PU.

J Exp Zool A Ecol Genet Physiol. 2016 Jan;325(1):41-51. doi: 10.1002/jez.1994. Epub 2015 Nov 10.


The separate and combined effects of monoamine oxidase A inhibition and nicotine on resting state EEG.

Smith DM, Fisher D, Blier P, Ilivitsky V, Knott V.

J Psychopharmacol. 2016 Jan;30(1):56-62. doi: 10.1177/0269881115613518. Epub 2015 Nov 4.


A review of the current nomenclature for psychotropic agents and an introduction to the Neuroscience-based Nomenclature.

Zohar J, Stahl S, Moller HJ, Blier P, Kupfer D, Yamawaki S, Uchida H, Spedding M, Goodwin GM, Nutt D.

Eur Neuropsychopharmacol. 2015 Dec;25(12):2318-25. doi: 10.1016/j.euroneuro.2015.08.019. Epub 2015 Sep 7. Review.


Brexpiprazole Alters Monoaminergic Systems following Repeated Administration: an in Vivo Electrophysiological Study.

Oosterhof CA, El Mansari M, Bundgaard C, Blier P.

Int J Neuropsychopharmacol. 2015 Oct 1;19(3):pyv111. doi: 10.1093/ijnp/pyv111.


Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation.

Etiévant A, Oosterhof C, Bétry C, Abrial E, Novo-Perez M, Rovera R, Scarna H, Devader C, Mazella J, Wegener G, Sánchez C, Dkhissi-Benyahya O, Gronfier C, Coizet V, Beaulieu JM, Blier P, Lucas G, Haddjeri N.

EBioMedicine. 2015 Jul 7;2(8):898-908. doi: 10.1016/j.ebiom.2015.06.023. eCollection 2015 Aug.


Long-term administration of the antidepressant vilazodone modulates rat brain monoaminergic systems.

El Mansari M, Crnic A, Oosterhof C, Blier P.

Neuropharmacology. 2015 Dec;99:696-704. doi: 10.1016/j.neuropharm.2015.09.007. Epub 2015 Sep 8.


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