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Items: 1 to 50 of 108

1.

PEPTIDES AND ASTROGLIA IMPROVE THE REGENERATIVE CAPACITY OF ALGINATE GELS IN THE INJURED SPINAL CORD.

Schackel T, Kumar P, Günther M, Liu S, Brunner M, Sandner B, Puttagunta R, Mueller R, Weidner N, Blesch A.

Tissue Eng Part A. 2018 Oct 23. doi: 10.1089/ten.TEA.2018.0082. [Epub ahead of print]

PMID:
30351234
2.

Targeted tissue engineering: hydrogels with linear capillary channels for axonal regeneration after spinal cord injury.

Liu S, Blesch A.

Neural Regen Res. 2018 Apr;13(4):641-642. doi: 10.4103/1673-5374.230286. No abstract available.

3.

Sensorimotor Activity Partially Ameliorates Pain and Reduces Nociceptive Fiber Density in the Chronically Injured Spinal Cord.

Sliwinski C, Nees TA, Puttagunta R, Weidner N, Blesch A.

J Neurotrauma. 2018 Sep 15;35(18):2222-2238. doi: 10.1089/neu.2017.5431. Epub 2018 Jun 29.

PMID:
29706124
4.

Systemic epothilone D improves hindlimb function after spinal cord contusion injury in rats.

Sandner B, Puttagunta R, Motsch M, Bradke F, Ruschel J, Blesch A, Weidner N.

Exp Neurol. 2018 Aug;306:250-259. doi: 10.1016/j.expneurol.2018.01.018. Epub 2018 Feb 2.

PMID:
29408734
5.

Cortical electrical stimulation in female rats with a cervical spinal cord injury to promote axonal outgrowth.

Jack AS, Hurd C, Forero J, Nataraj A, Fenrich K, Blesch A, Fouad K.

J Neurosci Res. 2018 May;96(5):852-862. doi: 10.1002/jnr.24209. Epub 2017 Dec 14.

PMID:
29239014
6.

Depolarization and electrical stimulation enhance in vitro and in vivo sensory axon growth after spinal cord injury.

Goganau I, Sandner B, Weidner N, Fouad K, Blesch A.

Exp Neurol. 2018 Feb;300:247-258. doi: 10.1016/j.expneurol.2017.11.011. Epub 2017 Nov 26.

PMID:
29183676
7.

Enhancing excitatory activity of somatosensory cortex alleviates neuropathic pain through regulating homeostatic plasticity.

Xiong W, Ping X, Ripsch MS, Chavez GSC, Hannon HE, Jiang K, Bao C, Jadhav V, Chen L, Chai Z, Ma C, Wu H, Feng J, Blesch A, White FA, Jin X.

Sci Rep. 2017 Oct 6;7(1):12743. doi: 10.1038/s41598-017-12972-6.

8.

Regulated viral BDNF delivery in combination with Schwann cells promotes axonal regeneration through capillary alginate hydrogels after spinal cord injury.

Liu S, Sandner B, Schackel T, Nicholson L, Chtarto A, Tenenbaum L, Puttagunta R, Müller R, Weidner N, Blesch A.

Acta Biomater. 2017 Sep 15;60:167-180. doi: 10.1016/j.actbio.2017.07.024. Epub 2017 Jul 19.

PMID:
28735026
9.

Neuropathic pain after spinal cord injury: the impact of sensorimotor activity.

Nees TA, Finnerup NB, Blesch A, Weidner N.

Pain. 2017 Mar;158(3):371-376. doi: 10.1097/j.pain.0000000000000783. Review. No abstract available.

PMID:
27941498
10.

Human ESC-Derived Interneurons Improve Major Consequences of Spinal Cord Injury.

Blesch A.

Cell Stem Cell. 2016 Oct 6;19(4):423-424. doi: 10.1016/j.stem.2016.09.008.

11.

A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program.

Chandran V, Coppola G, Nawabi H, Omura T, Versano R, Huebner EA, Zhang A, Costigan M, Yekkirala A, Barrett L, Blesch A, Michaelevski I, Davis-Turak J, Gao F, Langfelder P, Horvath S, He Z, Benowitz L, Fainzilber M, Tuszynski M, Woolf CJ, Geschwind DH.

Neuron. 2016 Mar 2;89(5):956-70. doi: 10.1016/j.neuron.2016.01.034. Epub 2016 Feb 18.

12.

Early-onset treadmill training reduces mechanical allodynia and modulates calcitonin gene-related peptide fiber density in lamina III/IV in a mouse model of spinal cord contusion injury.

Nees TA, Tappe-Theodor A, Sliwinski C, Motsch M, Rupp R, Kuner R, Weidner N, Blesch A.

Pain. 2016 Mar;157(3):687-97. doi: 10.1097/j.pain.0000000000000422.

PMID:
26588690
13.

Cell-seeded alginate hydrogel scaffolds promote directed linear axonal regeneration in the injured rat spinal cord.

Günther MI, Weidner N, Müller R, Blesch A.

Acta Biomater. 2015 Nov;27:140-150. doi: 10.1016/j.actbio.2015.09.001. Epub 2015 Sep 5.

PMID:
26348141
14.

AngleJ: A new tool for the automated measurement of neurite growth orientation in tissue sections.

Günther MI, Günther M, Schneiders M, Rupp R, Blesch A.

J Neurosci Methods. 2015 Aug 15;251:143-50. doi: 10.1016/j.jneumeth.2015.05.021. Epub 2015 Jun 5.

PMID:
26051555
15.

Large animal and primate models of spinal cord injury for the testing of novel therapies.

Kwon BK, Streijger F, Hill CE, Anderson AJ, Bacon M, Beattie MS, Blesch A, Bradbury EJ, Brown A, Bresnahan JC, Case CC, Colburn RW, David S, Fawcett JW, Ferguson AR, Fischer I, Floyd CL, Gensel JC, Houle JD, Jakeman LB, Jeffery ND, Jones LA, Kleitman N, Kocsis J, Lu P, Magnuson DS, Marsala M, Moore SW, Mothe AJ, Oudega M, Plant GW, Rabchevsky AS, Schwab JM, Silver J, Steward O, Xu XM, Guest JD, Tetzlaff W.

Exp Neurol. 2015 Jul;269:154-68. doi: 10.1016/j.expneurol.2015.04.008. Epub 2015 Apr 19.

PMID:
25902036
16.

Axonal amphoterin mRNA is regulated by translational control and enhances axon outgrowth.

Merianda TT, Coleman J, Kim HH, Kumar Sahoo P, Gomes C, Brito-Vargas P, Rauvala H, Blesch A, Yoo S, Twiss JL.

J Neurosci. 2015 Apr 8;35(14):5693-706. doi: 10.1523/JNEUROSCI.3397-14.2015.

17.

Limited Functional Effects of Subacute Syngeneic Bone Marrow Stromal Cell Transplantation After Rat Spinal Cord Contusion Injury.

Sandner B, Ciatipis M, Motsch M, Soljanik I, Weidner N, Blesch A.

Cell Transplant. 2016;25(1):125-39. doi: 10.3727/096368915X687679. Epub 2015 Mar 25.

PMID:
25812176
18.

Axonal regeneration. Systemic administration of epothilone B promotes axon regeneration after spinal cord injury.

Ruschel J, Hellal F, Flynn KC, Dupraz S, Elliott DA, Tedeschi A, Bates M, Sliwinski C, Brook G, Dobrindt K, Peitz M, Brüstle O, Norenberg MD, Blesch A, Weidner N, Bunge MB, Bixby JL, Bradke F.

Science. 2015 Apr 17;348(6232):347-52. doi: 10.1126/science.aaa2958. Epub 2015 Mar 12.

19.
20.

Neural stem cells in models of spinal cord injury.

Tuszynski MH, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Lu P.

Exp Neurol. 2014 Nov;261:494-500. doi: 10.1016/j.expneurol.2014.07.011. Epub 2014 Jul 28.

PMID:
25079369
21.

Thoracic rat spinal cord contusion injury induces remote spinal gliogenesis but not neurogenesis or gliogenesis in the brain.

Franz S, Ciatipis M, Pfeifer K, Kierdorf B, Sandner B, Bogdahn U, Blesch A, Winner B, Weidner N.

PLoS One. 2014 Jul 22;9(7):e102896. doi: 10.1371/journal.pone.0102896. eCollection 2014.

22.

[Novel aspects of diagnostics and therapy of spinal cord diseases].

Rupp R, Blesch A, Schad L, Draganski B, Weidner N.

Nervenarzt. 2014 Aug;85(8):946-54. doi: 10.1007/s00115-014-4037-3. Review. German.

PMID:
25001239
23.

Neural stem cell dissemination after grafting to CNS injury sites.

Tuszynski MH, Wang Y, Graham L, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Lu P.

Cell. 2014 Jan 30;156(3):388-9. doi: 10.1016/j.cell.2014.01.016. No abstract available.

24.

Long-term viral brain-derived neurotrophic factor delivery promotes spasticity in rats with a cervical spinal cord hemisection.

Fouad K, Bennett DJ, Vavrek R, Blesch A.

Front Neurol. 2013 Nov 19;4:187. doi: 10.3389/fneur.2013.00187. eCollection 2013.

25.

Partial restoration of cardiovascular function by embryonic neural stem cell grafts after complete spinal cord transection.

Hou S, Tom VJ, Graham L, Lu P, Blesch A.

J Neurosci. 2013 Oct 23;33(43):17138-49. doi: 10.1523/JNEUROSCI.2851-13.2013.

26.

Bone morphogenetic proteins prevent bone marrow stromal cell-mediated oligodendroglial differentiation of transplanted adult neural progenitor cells in the injured spinal cord.

Sandner B, Rivera FJ, Caioni M, Nicholson L, Eckstein V, Bogdahn U, Aigner L, Blesch A, Weidner N.

Stem Cell Res. 2013 Sep;11(2):758-71. doi: 10.1016/j.scr.2013.05.003. Epub 2013 May 16.

27.

Demonstrating efficacy in preclinical studies of cellular therapies for spinal cord injury - how much is enough?

Kwon BK, Soril LJ, Bacon M, Beattie MS, Blesch A, Bresnahan JC, Bunge MB, Dunlop SA, Fehlings MG, Ferguson AR, Hill CE, Karimi-Abdolrezaee S, Lu P, McDonald JW, Müller HW, Oudega M, Rosenzweig ES, Reier PJ, Silver J, Sykova E, Xu XM, Guest JD, Tetzlaff W.

Exp Neurol. 2013 Oct;248:30-44. doi: 10.1016/j.expneurol.2013.05.012. Epub 2013 May 29. Erratum in: Exp Neurol. 2013 Oct;248:299-300.

PMID:
23727091
28.

Characterization of supraspinal vasomotor pathways and autonomic dysreflexia after spinal cord injury in F344 rats.

Hou S, Lu P, Blesch A.

Auton Neurosci. 2013 Jun;176(1-2):54-63. doi: 10.1016/j.autneu.2013.02.001. Epub 2013 Mar 7.

PMID:
23466042
29.

Gene therapy, neurotrophic factors and spinal cord regeneration.

Blesch A, Fischer I, Tuszynski MH.

Handb Clin Neurol. 2012;109:563-74. doi: 10.1016/B978-0-444-52137-8.00035-8. Review.

PMID:
23098737
30.

Axonal transport of neural membrane protein 35 mRNA increases axon growth.

Merianda TT, Vuppalanchi D, Yoo S, Blesch A, Twiss JL.

J Cell Sci. 2013 Jan 1;126(Pt 1):90-102. doi: 10.1242/jcs.107268. Epub 2012 Oct 24.

31.

Dependence of regenerated sensory axons on continuous neurotrophin-3 delivery.

Hou S, Nicholson L, van Niekerk E, Motsch M, Blesch A.

J Neurosci. 2012 Sep 19;32(38):13206-20.

32.

BDNF: the career of a multifaceted neurotrophin in spinal cord injury.

Weishaupt N, Blesch A, Fouad K.

Exp Neurol. 2012 Dec;238(2):254-64. doi: 10.1016/j.expneurol.2012.09.001. Epub 2012 Sep 12. Review.

PMID:
22982152
33.

Long-distance growth and connectivity of neural stem cells after severe spinal cord injury.

Lu P, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Tuszynski MH.

Cell. 2012 Sep 14;150(6):1264-73. doi: 10.1016/j.cell.2012.08.020.

34.

Intrahippocampal transplantation of mesenchymal stromal cells promotes neuroplasticity.

Coquery N, Blesch A, Stroh A, Fernández-Klett F, Klein J, Winter C, Priller J.

Cytotherapy. 2012 Oct;14(9):1041-53. doi: 10.3109/14653249.2012.694418. Epub 2012 Jul 5.

PMID:
22762522
35.

Motor axonal regeneration after partial and complete spinal cord transection.

Lu P, Blesch A, Graham L, Wang Y, Samara R, Banos K, Haringer V, Havton L, Weishaupt N, Bennett D, Fouad K, Tuszynski MH.

J Neurosci. 2012 Jun 13;32(24):8208-18. doi: 10.1523/JNEUROSCI.0308-12.2012.

36.

Neurotrophic factors in combinatorial approaches for spinal cord regeneration.

McCall J, Weidner N, Blesch A.

Cell Tissue Res. 2012 Jul;349(1):27-37. doi: 10.1007/s00441-012-1388-6. Epub 2012 Apr 12. Review.

37.

Neural stem cells for spinal cord repair.

Sandner B, Prang P, Rivera FJ, Aigner L, Blesch A, Weidner N.

Cell Tissue Res. 2012 Jul;349(1):349-62. doi: 10.1007/s00441-012-1363-2. Epub 2012 Mar 3. Review.

PMID:
22388657
38.

Optimization of adult sensory neuron electroporation to study mechanisms of neurite growth.

McCall J, Nicholson L, Weidner N, Blesch A.

Front Mol Neurosci. 2012 Feb 8;5:11. doi: 10.3389/fnmol.2012.00011. eCollection 2012.

39.

Axonal transcription factors signal retrogradely in lesioned peripheral nerve.

Ben-Yaakov K, Dagan SY, Segal-Ruder Y, Shalem O, Vuppalanchi D, Willis DE, Yudin D, Rishal I, Rother F, Bader M, Blesch A, Pilpel Y, Twiss JL, Fainzilber M.

EMBO J. 2012 Mar 21;31(6):1350-63. doi: 10.1038/emboj.2011.494. Epub 2012 Jan 13.

40.

Conditioning lesions before or after spinal cord injury recruit broad genetic mechanisms that sustain axonal regeneration: superiority to camp-mediated effects.

Blesch A, Lu P, Tsukada S, Alto LT, Roet K, Coppola G, Geschwind D, Tuszynski MH.

Exp Neurol. 2012 May;235(1):162-73. doi: 10.1016/j.expneurol.2011.12.037. Epub 2011 Dec 29.

41.

Gene therapy approaches to enhancing plasticity and regeneration after spinal cord injury.

Franz S, Weidner N, Blesch A.

Exp Neurol. 2012 May;235(1):62-9. doi: 10.1016/j.expneurol.2011.01.015. Epub 2011 Jan 31. Review.

42.

TNF: a key neuroinflammatory mediator of neurotoxicity and neurodegeneration in models of Parkinson's disease.

McCoy MK, Ruhn KA, Blesch A, Tansey MG.

Adv Exp Med Biol. 2011;691:539-40. doi: 10.1007/978-1-4419-6612-4_56. No abstract available.

PMID:
21153359
43.

Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease.

Harms AS, Barnum CJ, Ruhn KA, Varghese S, Treviño I, Blesch A, Tansey MG.

Mol Ther. 2011 Jan;19(1):46-52. doi: 10.1038/mt.2010.217. Epub 2010 Oct 19.

44.

Local and remote growth factor effects after primate spinal cord injury.

Brock JH, Rosenzweig ES, Blesch A, Moseanko R, Havton LA, Edgerton VR, Tuszynski MH.

J Neurosci. 2010 Jul 21;30(29):9728-37. doi: 10.1523/JNEUROSCI.1924-10.2010.

45.

Regeneration of long-tract axons through sites of spinal cord injury using templated agarose scaffolds.

Gros T, Sakamoto JS, Blesch A, Havton LA, Tuszynski MH.

Biomaterials. 2010 Sep;31(26):6719-29. doi: 10.1016/j.biomaterials.2010.04.035. Epub 2010 Jun 17.

PMID:
20619785
46.

Effects of cavernous nerve reconstruction on expression of nitric oxide synthase isoforms in rats.

Schlenker B, Matiasek K, Saur D, Gratzke C, Bauer RM, Herouy Y, Arndt C, Blesch A, Hartung R, Stief CG, Weidner N, May F.

BJU Int. 2010 Dec;106(11):1726-31. doi: 10.1111/j.1464-410X.2010.09364.x.

47.

Conserved 3'-untranslated region sequences direct subcellular localization of chaperone protein mRNAs in neurons.

Vuppalanchi D, Coleman J, Yoo S, Merianda TT, Yadhati AG, Hossain J, Blesch A, Willis DE, Twiss JL.

J Biol Chem. 2010 Jun 4;285(23):18025-38. doi: 10.1074/jbc.M109.061333. Epub 2010 Mar 22.

48.

A dual promoter lentiviral vector for the in vivo evaluation of gene therapeutic approaches to axon regeneration after spinal cord injury.

Löw K, Blesch A, Herrmann J, Tuszynski MH.

Gene Ther. 2010 May;17(5):577-91. doi: 10.1038/gt.2010.14. Epub 2010 Mar 4.

PMID:
20200564
49.

Promoting directional axon growth from neural progenitors grafted into the injured spinal cord.

Bonner JF, Blesch A, Neuhuber B, Fischer I.

J Neurosci Res. 2010 May 1;88(6):1182-92. doi: 10.1002/jnr.22288.

50.

Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury.

Kadoya K, Tsukada S, Lu P, Coppola G, Geschwind D, Filbin MT, Blesch A, Tuszynski MH.

Neuron. 2009 Oct 29;64(2):165-72. doi: 10.1016/j.neuron.2009.09.016.

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